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Volumn 11, Issue 12, 1996, Pages 1155-1160

Efficacy of ursodeoxycholic acid in combination with interferon-α in treating chronic hepatitis C: Results of a long-term follow-up trial

Author keywords

chronic hepatitis C; HCV RNA; interferon; ursodeoxycholic acid

Indexed keywords

ALPHA INTERFERON; RECOMBINANT ALPHA2A INTERFERON; URSODEOXYCHOLIC ACID;

EID: 0030482377     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.1996.tb01844.x     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 0024511734 scopus 로고
    • An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis
    • Kuo G, Choo QL, Alter HJ et al. An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 1989; 244: 362-4.
    • (1989) Science , vol.244 , pp. 362-364
    • Kuo, G.1    Choo, Q.L.2    Alter, H.J.3
  • 2
    • 0025037547 scopus 로고
    • Inter-relationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus
    • Kiyosawa K, Sodeyama T, Tanaka E et al. Inter-relationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: Analysis by detection of antibody to hepatitis C virus. Hepatology 1990; 12: 671-5.
    • (1990) Hepatology , vol.12 , pp. 671-675
    • Kiyosawa, K.1    Sodeyama, T.2    Tanaka, E.3
  • 3
    • 0020560639 scopus 로고
    • Non-A, non-B hepatitis. I. Recognition, epidemiology, and clinical features
    • Dienstag JL. Non-A, non-B hepatitis. I. Recognition, epidemiology, and clinical features. Gastroenterology 1983; 85: 439-62.
    • (1983) Gastroenterology , vol.85 , pp. 439-462
    • Dienstag, J.L.1
  • 4
    • 0022868893 scopus 로고
    • Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon: A preliminary report
    • Hoofnagle JH, Mullen KD, Jones DB et al. Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon: A preliminary report. N. Engl. J. Med. 1986; 315: 1575-8.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1575-1578
    • Hoofnagle, J.H.1    Mullen, K.D.2    Jones, D.B.3
  • 5
    • 0024368522 scopus 로고
    • Treatment of chronic hepatitis C with recombinant interferon alpha: A multicenter randomized, controlled trial
    • Davis GL, Balart LA, Schiff ER et al. Treatment of chronic hepatitis C with recombinant interferon alpha: A multicenter randomized, controlled trial. N. Engl. J. Med. 1989; 321: 1501-6.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1501-1506
    • Davis, G.L.1    Balart, L.A.2    Schiff, E.R.3
  • 6
    • 0024981607 scopus 로고
    • Recombinant interferon alpha therapy for chronic hepatitis C: A randomized, double-blind, placebo-controlled trial
    • Di Bisceglie AM, Martin P, Kassianides C et al. Recombinant interferon alpha therapy for chronic hepatitis C: A randomized, double-blind, placebo-controlled trial. N. Engl. J. Med. 1989; 321: 1506-10.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1506-1510
    • Di Bisceglie, A.M.1    Martin, P.2    Kassianides, C.3
  • 7
    • 0025915674 scopus 로고
    • Interferon for non-A, non-B chronic hepatitis: A meta-analysis of randomized clinical trials
    • Tine F, Margin S, Craxi A, Pagliaro L. Interferon for non-A, non-B chronic hepatitis: A meta-analysis of randomized clinical trials. J. Hepatol. 1991; 13: 192-9.
    • (1991) J. Hepatol. , vol.13 , pp. 192-199
    • Tine, F.1    Margin, S.2    Craxi, A.3    Pagliaro, L.4
  • 8
    • 0025732689 scopus 로고
    • Recombinant human α-interferon in patients with chronic non-A, non-B hepatitis: A multicenter randomized controlled trial from France
    • Marcellin P, Boyer N, Giostra E et al. Recombinant human α-interferon in patients with chronic non-A, non-B hepatitis: A multicenter randomized controlled trial from France. Hepatology 1991; 13: 393-7.
    • (1991) Hepatology , vol.13 , pp. 393-397
    • Marcellin, P.1    Boyer, N.2    Giostra, E.3
  • 9
    • 0025876404 scopus 로고
    • A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis
    • Poupon RE, Balkau B, Eschwege E, Poupon R, the UDCA-PBC Study Group. A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. N. Engl. J. Med. 1991; 324: 1548-54.
    • (1991) N. Engl. J. Med. , vol.324 , pp. 1548-1554
    • Poupon, R.E.1    Balkau, B.2    Eschwege, E.3    Poupon, R.4
  • 10
    • 0026062522 scopus 로고
    • Effects of ursodeoxycholic acid on serum liver enzymes and bile acid metabolism in chronic active hepatitis: A dose-response study
    • Crosignani A, Battezzati PM, Setchell KDR et al. Effects of ursodeoxycholic acid on serum liver enzymes and bile acid metabolism in chronic active hepatitis: A dose-response study. Hepatology 1991; 13: 339-44.
    • (1991) Hepatology , vol.13 , pp. 339-344
    • Crosignani, A.1    Battezzati, P.M.2    Setchell, K.D.R.3
  • 12
    • 0025251873 scopus 로고
    • Treatment of chronic liver disease with ursodeoxycholic acid
    • Guslandi M. Treatment of chronic liver disease with ursodeoxycholic acid. J. Int. Med. Res. 1990; 18: 497-505.
    • (1990) J. Int. Med. Res. , vol.18 , pp. 497-505
    • Guslandi, M.1
  • 13
    • 0024834972 scopus 로고
    • Effect of different doses of ursodeoxycholic acid in chronic liver disease
    • Podda M, Ghezzi C, Battezzati PM et al. Effect of different doses of ursodeoxycholic acid in chronic liver disease. Dig. Dis. Sci. 1989; 34 (Suppl.): S59-65.
    • (1989) Dig. Dis. Sci. , vol.34 , Issue.SUPPL.
    • Podda, M.1    Ghezzi, C.2    Battezzati, P.M.3
  • 14
    • 0025782642 scopus 로고
    • Effects of ursodeoxycholic acid (UDCA) on serum liver damage indices in patients with chronic active hepatitis. A double-blind controlled study
    • Rolandi E, Franceschini R, Cataldi A, Cicchetti V, Carati L, Barreca T. Effects of ursodeoxycholic acid (UDCA) on serum liver damage indices in patients with chronic active hepatitis. A double-blind controlled study. Eur. J. Clin. Pharmacol. 1991; 40: 473-6.
    • (1991) Eur. J. Clin. Pharmacol. , vol.40 , pp. 473-476
    • Rolandi, E.1    Franceschini, R.2    Cataldi, A.3    Cicchetti, V.4    Carati, L.5    Barreca, T.6
  • 15
    • 0027715655 scopus 로고
    • Ursodiol in the long-term treatment of chronic hepatitis: A double-blind multicenter clinical trial
    • Bellentani S, Podda M, Tiribelli C et al. Ursodiol in the long-term treatment of chronic hepatitis: A double-blind multicenter clinical trial. J. Hepatol. 1993; 19: 459-64.
    • (1993) J. Hepatol. , vol.19 , pp. 459-464
    • Bellentani, S.1    Podda, M.2    Tiribelli, C.3
  • 16
    • 0028814835 scopus 로고
    • Recombinant interferon-α and ursodeoxycholic acid versus interferon-α alone in the treatment of chronic hepatitis C: A randomized clinical trial with long-term follow-up
    • Angelico M, Gandin C, Pescarmona E et al. Recombinant interferon-α and ursodeoxycholic acid versus interferon-α alone in the treatment of chronic hepatitis C: A randomized clinical trial with long-term follow-up. Am. J. Gastroenterol. 1995; 90: 263-9.
    • (1995) Am. J. Gastroenterol. , vol.90 , pp. 263-269
    • Angelico, M.1    Gandin, C.2    Pescarmona, E.3
  • 17
    • 0028960364 scopus 로고
    • Interferon and ursodeoxycholic acid combined therapy in the treatment of chronic viral C hepatitis: Results from a controlled randomized trial in 80 patients
    • Boucher E, Jouanolle H, Andre P et al. Interferon and ursodeoxycholic acid combined therapy in the treatment of chronic viral C hepatitis: Results from a controlled randomized trial in 80 patients. Hepatology 1995; 21: 322-7.
    • (1995) Hepatology , vol.21 , pp. 322-327
    • Boucher, E.1    Jouanolle, H.2    Andre, P.3
  • 18
    • 0023277545 scopus 로고
    • Single-step RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987; 162: 156-9.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 19
    • 0001442557 scopus 로고
    • Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes
    • Saiki RK, Walsh PS, Levenson CH, Erlich HA. Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes. Proc. Natl Acad. Sci. USA 1989; 86: 6230-4.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 6230-6234
    • Saiki, R.K.1    Walsh, P.S.2    Levenson, C.H.3    Erlich, H.A.4
  • 20
    • 0028139547 scopus 로고
    • Specific detection of positive and negative stranded hepatitis C viral RNA using chemical RNA modification
    • Gunji T, Kato N, Hijikata M, Hayashi K, Saitoh S, Shimotohno K. Specific detection of positive and negative stranded hepatitis C viral RNA using chemical RNA modification. Arch. Virol. 1994; 134: 293-302.
    • (1994) Arch. Virol. , vol.134 , pp. 293-302
    • Gunji, T.1    Kato, N.2    Hijikata, M.3    Hayashi, K.4    Saitoh, S.5    Shimotohno, K.6
  • 21
    • 0024973417 scopus 로고
    • Avoiding false positives with PCR
    • Kwok S, Higuchi R. Avoiding false positives with PCR. Nature 1989; 339: 237-8.
    • (1989) Nature , vol.339 , pp. 237-238
    • Kwok, S.1    Higuchi, R.2
  • 22
    • 0025355882 scopus 로고
    • Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction
    • Gilliland G, Perrin S, Blanchard K, Bunn HF. Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction. Proc. Natl Acad. Sci. USA 1990; 87: 2725-9.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 2725-2729
    • Gilliland, G.1    Perrin, S.2    Blanchard, K.3    Bunn, H.F.4
  • 23
    • 0026563204 scopus 로고
    • Typing hepatitis C virus by polymerase chain reaction with type-specific primers: Application to clinical surveys and tracing infections sources
    • Okamoto H, Sugiyama Y, Okada S et al. Typing hepatitis C virus by polymerase chain reaction with type-specific primers: Application to clinical surveys and tracing infections sources. J. Gen. Virol. 1992; 73: 673-9.
    • (1992) J. Gen. Virol. , vol.73 , pp. 673-679
    • Okamoto, H.1    Sugiyama, Y.2    Okada, S.3
  • 25
    • 0021178162 scopus 로고
    • Influence of hydroxylation and conjugation of bile salts on their membrane damaging properties: Studies on isolated hepatocytes and lipid membrane vesicles
    • Scholmerich J, Becher MS, Schmidt K et al. Influence of hydroxylation and conjugation of bile salts on their membrane damaging properties: Studies on isolated hepatocytes and lipid membrane vesicles. Hepatology 1984; 4: 661-6.
    • (1984) Hepatology , vol.4 , pp. 661-666
    • Scholmerich, J.1    Becher, M.S.2    Schmidt, K.3
  • 26
    • 0026086134 scopus 로고
    • Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat
    • Heuman DM, Mills AS, McCall J, Hylemon PB, Pandak WM, Vlahcevic ZR. Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat. Gastroenterology 1991; 100: 203-11.
    • (1991) Gastroenterology , vol.100 , pp. 203-211
    • Heuman, D.M.1    Mills, A.S.2    McCall, J.3    Hylemon, P.B.4    Pandak, W.M.5    Vlahcevic, Z.R.6
  • 27
    • 0027404908 scopus 로고
    • Quantitative analysis of hepatitis C virus RNA in serum during interferon alpha therapy
    • Hagiwara H, Hayashi N, Mita E et al. Quantitative analysis of hepatitis C virus RNA in serum during interferon alpha therapy. Gastroenterology 1993; 104: 877-83.
    • (1993) Gastroenterology , vol.104 , pp. 877-883
    • Hagiwara, H.1    Hayashi, N.2    Mita, E.3
  • 28
    • 0027370657 scopus 로고
    • Hepatic and extrahepatic HCV-RNA strands in chronic hepatitis C: Different patterns of response to IFN treatment
    • Gil B, Quian C, Riezu-Boj JI, Civeira MP, Prieto J. Hepatic and extrahepatic HCV-RNA strands in chronic hepatitis C: Different patterns of response to IFN treatment. Hepatology 1993; 18: 1050-4.
    • (1993) Hepatology , vol.18 , pp. 1050-1054
    • Gil, B.1    Quian, C.2    Riezu-Boj, J.I.3    Civeira, M.P.4    Prieto, J.5
  • 29
    • 0026575826 scopus 로고
    • Temporal relationships of hepatitis C virus RNA and antibody responses following experimental infection of chimpanzees
    • Beach MJ, Meeks EL, Mimms LT et al. Temporal relationships of hepatitis C virus RNA and antibody responses following experimental infection of chimpanzees. J. Med. Virol. 1992; 36: 226-37.
    • (1992) J. Med. Virol. , vol.36 , pp. 226-237
    • Beach, M.J.1    Meeks, E.L.2    Mimms, L.T.3
  • 30
    • 0027276247 scopus 로고
    • Significance of serum hepatitis C virus RNA levels in chronic hepatitis C
    • Lau JYN, Davis GL, Kniffen J et al. Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 1993; 341: 1501-4.
    • (1993) Lancet , vol.341 , pp. 1501-1504
    • Lau, J.Y.N.1    Davis, G.L.2    Kniffen, J.3
  • 31
    • 0021335877 scopus 로고
    • Ursodeoxycholic acid: Review of its pharmacological properties and therapeutic efficacy
    • Ward A, Broyden RN, Heel RC et al. Ursodeoxycholic acid: Review of its pharmacological properties and therapeutic efficacy. Drugs 1984; 27: 95-131.
    • (1984) Drugs , vol.27 , pp. 95-131
    • Ward, A.1    Broyden, R.N.2    Heel, R.C.3
  • 32
    • 0025098908 scopus 로고
    • Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: Effect of ursodeoxycholic acid
    • Calmus Y, Gane P, Rouger P, Poupon R. Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: Effect of ursodeoxycholic acid. Hepatology 1990; 11: 12-15.
    • (1990) Hepatology , vol.11 , pp. 12-15
    • Calmus, Y.1    Gane, P.2    Rouger, P.3    Poupon, R.4
  • 33
    • 0027932658 scopus 로고
    • Bile acids modulate hepatocyte HLA class I expression in human hepatocytes by a transcriptional mechanism
    • Hillaire H, Boucher E, Calmus Y et al. Bile acids modulate hepatocyte HLA class I expression in human hepatocytes by a transcriptional mechanism. Gastroenterology 1994; 107: 781-8.
    • (1994) Gastroenterology , vol.107 , pp. 781-788
    • Hillaire, H.1    Boucher, E.2    Calmus, Y.3
  • 34
    • 0026787739 scopus 로고
    • Intrahepatic lymphocyte subpopulations and HLA class I antigen expression by hepatocytes in chronic hepatitis C
    • Onji M, Kikuchi T, Kumon I et al. Intrahepatic lymphocyte subpopulations and HLA class I antigen expression by hepatocytes in chronic hepatitis C. Hepatogastroenterology 1992; 39: 340-3.
    • (1992) Hepatogastroenterology , vol.39 , pp. 340-343
    • Onji, M.1    Kikuchi, T.2    Kumon, I.3
  • 35
    • 0026506654 scopus 로고
    • Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology
    • Negro F, Pacchioni D, Shimizu Y. Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology. Proc. Natl Acad. Sci. USA 1992; 89: 2247-51.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 2247-2251
    • Negro, F.1    Pacchioni, D.2    Shimizu, Y.3
  • 36
    • 0027963209 scopus 로고
    • A multicenter randomized controlled dose study of ursodeoxycholic acid for chronic hepatitis C
    • Takano S, Ito Y, Yokosuka O et al. A multicenter randomized controlled dose study of ursodeoxycholic acid for chronic hepatitis C. Hepatology 1994; 20: 558-64.
    • (1994) Hepatology , vol.20 , pp. 558-564
    • Takano, S.1    Ito, Y.2    Yokosuka, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.