메뉴 건너뛰기




Volumn 21, Issue 1, 1998, Pages 17-25

A repressor function for telomerase activity in telomerase-negative immortal cells

Author keywords

Cell hybrid; Senescence, telomere; Telomerase

Indexed keywords

TELOMERASE;

EID: 0031908803     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199801)21:1<17::AID-MC4>3.0.CO;2-M     Document Type: Article
Times cited : (25)

References (50)
  • 1
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37:614-636, 1965.
    • (1965) Exp Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 2
    • 0019305047 scopus 로고
    • Limited lifespan in somatic cell hybrids and cybrids
    • Bunn CL, Tarrant GM. Limited lifespan in somatic cell hybrids and cybrids. Exp Cell Res 127:385-396, 1980.
    • (1980) Exp Cell Res , vol.127 , pp. 385-396
    • Bunn, C.L.1    Tarrant, G.M.2
  • 3
    • 0019150024 scopus 로고
    • Replicative potentials of various fusion products between WI-38 and SV40 transformed WI-38 cells and their components
    • Muggleton-Harris AL, De Simone DW. Replicative potentials of various fusion products between WI-38 and SV40 transformed WI-38 cells and their components. Somat Cell Mol Genet 6:689-698, 1980.
    • (1980) Somat Cell Mol Genet , vol.6 , pp. 689-698
    • Muggleton-Harris, A.L.1    De Simone, D.W.2
  • 4
    • 0020610446 scopus 로고
    • Evidence for the recessive nature of cellular immortality
    • Pereira-Smith OM, Smith JR. Evidence for the recessive nature of cellular immortality. Science 221:964-966, 1983.
    • (1983) Science , vol.221 , pp. 964-966
    • Pereira-Smith, O.M.1    Smith, J.R.2
  • 5
    • 0025020081 scopus 로고
    • Introduction of cellular senescence in immortalized cells by human chromosome 1
    • Sugawara O, Oshimura M, Koi M, Anneb LA, Barrett JC. Introduction of cellular senescence in immortalized cells by human chromosome 1. Science 247:707-710, 1990.
    • (1990) Science , vol.247 , pp. 707-710
    • Sugawara, O.1    Oshimura, M.2    Koi, M.3    Anneb, L.A.4    Barrett, J.C.5
  • 6
    • 0011208723 scopus 로고
    • Genetic analysis of indefinite division in human cells: Identification of four complementation groups
    • Pereira-Smith OM, Smith JR. Genetic analysis of indefinite division in human cells: Identification of four complementation groups. Proc Natl Acad Sci USA 85:6042-6046, 1988.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6042-6046
    • Pereira-Smith, O.M.1    Smith, J.R.2
  • 7
    • 0027231784 scopus 로고
    • Tumor cell growth arrest caused by chromosomal transferable DNA fragments from chromosome 11
    • Koi M, Johnson LA, Kalikin LM, Little PFR, Nakamura Y, Feinberg AP. Tumor cell growth arrest caused by chromosomal transferable DNA fragments from chromosome 11. Science 260:361-364, 1993.
    • (1993) Science , vol.260 , pp. 361-364
    • Koi, M.1    Johnson, L.A.2    Kalikin, L.M.3    Little, P.F.R.4    Nakamura, Y.5    Feinberg, A.P.6
  • 8
    • 0025953702 scopus 로고
    • Genetic analysis of indefinite division in human cells: Evidence for a cell senescence-related gene(s) on human chromosome 4
    • Ning Y, Weber JL, Killary AM, Ledbetter DH, Smith JR, Pereira-Smith OM. Genetic analysis of indefinite division in human cells: Evidence for a cell senescence-related gene(s) on human chromosome 4. Proc Natl Acad Sci USA 88:5635-5639, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5635-5639
    • Ning, Y.1    Weber, J.L.2    Killary, A.M.3    Ledbetter, D.H.4    Smith, J.R.5    Pereira-Smith, O.M.6
  • 9
    • 0027382325 scopus 로고
    • Chromosome 7 suppresses indefinite division of non-tumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1
    • Ogata T, Ayusawa D, Namba M, Takahashi E, Oshimura M, Oishi M. Chromosome 7 suppresses indefinite division of non-tumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1. Mol Cell Biol 13:6036-6043, 1993.
    • (1993) Mol Cell Biol , vol.13 , pp. 6036-6043
    • Ogata, T.1    Ayusawa, D.2    Namba, M.3    Takahashi, E.4    Oshimura, M.5    Oishi, M.6
  • 10
    • 0028883950 scopus 로고
    • Restoration of the cellular senescence program and repression of telomerase by human chromosome 3
    • Ohmura H, Tahara H, Suzuki M, et al. Restoration of the cellular senescence program and repression of telomerase by human chromosome 3. Jpn J Cancer Res 86:899-904, 1995.
    • (1995) Jpn J Cancer Res , vol.86 , pp. 899-904
    • Ohmura, H.1    Tahara, H.2    Suzuki, M.3
  • 12
    • 0025184730 scopus 로고
    • Multiple chromosomes carrying tumor suppressor activity for a uterine endometrial cell line indicated by microcell-mediated chromosome transfer
    • Yamada H, Wake N, Fujimoto S, Barrett JC, Oshimura M. Multiple chromosomes carrying tumor suppressor activity for a uterine endometrial cell line indicated by microcell-mediated chromosome transfer. Oncogene 5:1141-1147, 1990.
    • (1990) Oncogene , vol.5 , pp. 1141-1147
    • Yamada, H.1    Wake, N.2    Fujimoto, S.3    Barrett, J.C.4    Oshimura, M.5
  • 13
    • 0028270967 scopus 로고
    • In vitro growth suppression and morphological change in a human renal cell carcinoma cell line by the introduction of normal chromosome 3 via microcell fusion
    • Yoshida MA, Shimizu M, Ikeuchi T, Tonomura A, Yokota J, Oshimura M. In vitro growth suppression and morphological change in a human renal cell carcinoma cell line by the introduction of normal chromosome 3 via microcell fusion. Mol Carcinog 9:114-121, 1994.
    • (1994) Mol Carcinog , vol.9 , pp. 114-121
    • Yoshida, M.A.1    Shimizu, M.2    Ikeuchi, T.3    Tonomura, A.4    Yokota, J.5    Oshimura, M.6
  • 14
    • 0030979581 scopus 로고    scopus 로고
    • Multiple pathways to cellular senescence: Role of telomerase repressers
    • Oshimura M, Barrett JC. Multiple pathways to cellular senescence: Role of telomerase repressers. Eur J Cancer 33:703-709, 1997.
    • (1997) Eur J Cancer , vol.33 , pp. 703-709
    • Oshimura, M.1    Barrett, J.C.2
  • 15
    • 0029091869 scopus 로고
    • Normal human chromosome 2 induces cellular senescence in the human cervical carcinoma cell line SiHa
    • Uejima H, Mitsuya K, Kugoh H, Horikawa I, Oshimura M. Normal human chromosome 2 induces cellular senescence in the human cervical carcinoma cell line SiHa. Genes Chromosomes Cancer 14:120-127, 1995.
    • (1995) Genes Chromosomes Cancer , vol.14 , pp. 120-127
    • Uejima, H.1    Mitsuya, K.2    Kugoh, H.3    Horikawa, I.4    Oshimura, M.5
  • 16
    • 0025472467 scopus 로고
    • Telomeres, telomerase and senescence
    • Greider CW. Telomeres, telomerase and senescence. Bioassays 12:363-369, 1990.
    • (1990) Bioassays , vol.12 , pp. 363-369
    • Greider, C.W.1
  • 17
    • 0025787643 scopus 로고
    • Telomere loss: Mitotic clock or genetic time bomb
    • Harley CB. Telomere loss: Mitotic clock or genetic time bomb. Mutat Res 256:271-282, 1991.
    • (1991) Mutat Res , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 18
    • 0026682717 scopus 로고
    • Telomere positional effects and the regulation of cellular senescence
    • Wright WE, Shay JW. Telomere positional effects and the regulation of cellular senescence. Trends Genet 8:193-197, 1992.
    • (1992) Trends Genet , vol.8 , pp. 193-197
    • Wright, W.E.1    Shay, J.W.2
  • 19
    • 0026541384 scopus 로고
    • Human telomeres are attached to the nuclear matrix
    • De Lange T. Human telomeres are attached to the nuclear matrix. EMBO J 11:717-724, 1992.
    • (1992) EMBO J , vol.11 , pp. 717-724
    • De Lange, T.1
  • 20
    • 0024788528 scopus 로고
    • Structure and function of telomeres
    • Zakian VA. Structure and function of telomeres. Annu Rev Genet 23:579-604, 1989.
    • (1989) Annu Rev Genet , vol.23 , pp. 579-604
    • Zakian, V.A.1
  • 21
    • 0015844590 scopus 로고
    • A theory of marginotomy
    • Olovnikov AM. A theory of marginotomy. J Theor Biol 41:181-190, 1973.
    • (1973) J Theor Biol , vol.41 , pp. 181-190
    • Olovnikov, A.M.1
  • 22
    • 0015515155 scopus 로고
    • Origin of concatemeric T4 DNA
    • Watson JD. Origin of concatemeric T4 DNA. Nature 239:197-201, 1972.
    • (1972) Nature , vol.239 , pp. 197-201
    • Watson, J.D.1
  • 23
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43:405-413, 1985.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 24
    • 0024325562 scopus 로고
    • The human telomere terminal transferase is a ribo- Nucleoprotein that synthesizes TTAGGG repeats
    • Morin GB. The human telomere terminal transferase is a ribo- nucleoprotein that synthesizes TTAGGG repeats. Cell 59:521-529,1989.
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1
  • 25
    • 0029066169 scopus 로고
    • Telomerase activity in normal and malignant hematopoietic cells
    • Broccoli D, Young JW, De Lange T. Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci USA 92:9082-9086, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9082-9086
    • Broccoli, D.1    Young, J.W.2    De Lange, T.3
  • 26
    • 0028938262 scopus 로고
    • Telomerase activity in normal leukocytes and in hematologic malignancies
    • Counter CM, Gupta J, Harley CB, Leber B, Bacchetti S. Telomerase activity in normal leukocytes and in hematologic malignancies. Blood 85:2315-2320, 1995.
    • (1995) Blood , vol.85 , pp. 2315-2320
    • Counter, C.M.1    Gupta, J.2    Harley, C.B.3    Leber, B.4    Bacchetti, S.5
  • 27
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter CM, Avillon AA, LeFeuvre E, et al. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11:1921-1929, 1992.
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avillon, A.A.2    LeFeuvre, E.3
  • 28
    • 0027263711 scopus 로고
    • E6 of human papilomavirus 16 can overcome the M1 stage of immortalization in human mammary epithelial cells but not in human fibroblasts
    • Shay JW, Wright WE, Brasyskyte D, Van der Haegen BA. E6 of human papilomavirus 16 can overcome the M1 stage of immortalization in human mammary epithelial cells but not in human fibroblasts. Oncogene 8:1407-1413, 1993.
    • (1993) Oncogene , vol.8 , pp. 1407-1413
    • Shay, J.W.1    Wright, W.E.2    Brasyskyte, D.3    Van der Haegen, B.A.4
  • 29
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan TM, Englezou A, Gupta J, Bacchetti S, Reddel RR. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J 14:4240-4248, 1995.
    • (1995) EMBO J , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 30
    • 0030570417 scopus 로고    scopus 로고
    • Spontaneous immortalization of cultured skin fibroblasts obtained from a high dose atomic bomb survivor
    • Honda T, Sadamori N, Oshimura M, et al. Spontaneous immortalization of cultured skin fibroblasts obtained from a high dose atomic bomb survivor. Mutat Res 354:15-26, 1996.
    • (1996) Mutat Res , vol.354 , pp. 15-26
    • Honda, T.1    Sadamori, N.2    Oshimura, M.3
  • 31
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse R, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 266:2011-2015, 1994.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, R.3
  • 32
    • 0028981380 scopus 로고
    • INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts
    • INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts. Mol Cell Biol 15:4745-4753, 1995.
    • (1995) Mol Cell Biol , vol.15 , pp. 4745-4753
    • Rogan, E.M.1    Bryan, T.M.2    Hukku, B.3
  • 34
  • 35
    • 0029655485 scopus 로고    scopus 로고
    • Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines
    • Strahl C, Blackburn EH. Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines. Mol Cell Biol 16:53-65, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 53-65
    • Strahl, C.1    Blackburn, E.H.2
  • 37
    • 0029023065 scopus 로고
    • Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity
    • Wright WE, Shay JW, Piatyszek MA. Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity. Nucleic Acids Res 23:3794-3795, 1995.
    • (1995) Nucleic Acids Res , vol.23 , pp. 3794-3795
    • Wright, W.E.1    Shay, J.W.2    Piatyszek, M.A.3
  • 38
    • 0021269995 scopus 로고
    • Structure of the growing telomeres of trypanosomes
    • Van der Ploeg LHT, Liu AYC, Borst P. Structure of the growing telomeres of trypanosomes. Cell 36:459-468, 1984.
    • (1984) Cell , vol.36 , pp. 459-468
    • Van der Ploeg, L.H.T.1    Liu, A.Y.C.2    Borst, P.3
  • 39
    • 0029001463 scopus 로고
    • Isolation and mapping of 196 new DNA markers on human chromosome 1
    • Kugoh H, Nakagawa Y, Mitsuya K, et al. Isolation and mapping of 196 new DNA markers on human chromosome 1. Genomics 27:207-210, 1995.
    • (1995) Genomics , vol.27 , pp. 207-210
    • Kugoh, H.1    Nakagawa, Y.2    Mitsuya, K.3
  • 41
    • 0028890828 scopus 로고
    • Genetic complementation of the immortal phenotype in group D cell lines by introduction of chromosome 7
    • Ogata T, Oshimura M, Namba M, Fujii M, Oishi M, Ayusawa D. Genetic complementation of the immortal phenotype in group D cell lines by introduction of chromosome 7. Jpn J Cancer Res 86:35-40, 1995.
    • (1995) Jpn J Cancer Res , vol.86 , pp. 35-40
    • Ogata, T.1    Oshimura, M.2    Namba, M.3    Fujii, M.4    Oishi, M.5    Ayusawa, D.6
  • 45
    • 2642701248 scopus 로고
    • Chromosome patterns in hybrid cells
    • Academic Press, New York, San Francisco, London
    • Ringertz NR, Savage RE. Chromosome patterns in hybrid cells. In: Cell Hybrids. Academic Press, New York, San Francisco, London, 1976, pp. 162-179.
    • (1976) Cell Hybrids , pp. 162-179
    • Ringertz, N.R.1    Savage, R.E.2
  • 47
    • 0029145379 scopus 로고
    • Evidence for a critical tetomere length in senescent human fibroblasts
    • Allsopp RC, Harley CB. Evidence for a critical tetomere length in senescent human fibroblasts. Exp Cell Res 219:130-136, 1995.
    • (1995) Exp Cell Res , vol.219 , pp. 130-136
    • Allsopp, R.C.1    Harley, C.B.2
  • 48
    • 0030004489 scopus 로고    scopus 로고
    • Experimental elongation of telomeres expands the lifespan of immortal × nor- Mal cell hybrids
    • Wright WE, Brasiskyte D, Piatyszek MA, Shay JW. Experimental elongation of telomeres expands the lifespan of immortal × nor- mal cell hybrids. EMBO J 15:1734-1741, 1996.
    • (1996) EMBO J , vol.15 , pp. 1734-1741
    • Wright, W.E.1    Brasiskyte, D.2    Piatyszek, M.A.3    Shay, J.W.4
  • 50
    • 0025115349 scopus 로고
    • Structure and variability of human chromosome ends
    • De Lange T, Shiue L, Myers RM, et al. Structure and variability of human chromosome ends. Mol Cell Biol 10:518-527, 1990.
    • (1990) Mol Cell Biol , vol.10 , pp. 518-527
    • De Lange, T.1    Shiue, L.2    Myers, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.