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Volumn 66, Issue 5, 1998, Pages 1898-1903

Identification of the aspartate-β-semialdehyde dehydrogenase gene of Legionella pneumophila and characterization of a null mutant

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE SEMIALDEHYDE DEHYDROGENASE; DIAMINOPIMELIC ACID; LIVE VACCINE;

EID: 0031901409     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.5.1898-1903.1998     Document Type: Article
Times cited : (55)

References (45)
  • 1
    • 0029980810 scopus 로고    scopus 로고
    • The phagosome containing Legionella pneumophila within the protozoan Harmannella vermiformis is surrounded by the rough endoplasmic reticulum
    • Abu Kwaik, Y. 1996. The phagosome containing Legionella pneumophila within the protozoan Harmannella vermiformis is surrounded by the rough endoplasmic reticulum. Appl. Environ. Microbiol. 62:2022-2028.
    • (1996) Appl. Environ. Microbiol. , vol.62 , pp. 2022-2028
    • Abu Kwaik, Y.1
  • 2
    • 0345180087 scopus 로고    scopus 로고
    • Induced expression of a 20-kDa encoding gene of Legionella pneumophila during intracellular infection
    • Abu Kwaik, Y. 1998. Induced expression of a 20-kDa encoding gene of Legionella pneumophila during intracellular infection. Infect. Immun. 66: 203-212.
    • (1998) Infect. Immun. , vol.66 , pp. 203-212
    • Abu Kwaik, Y.1
  • 3
    • 0027417230 scopus 로고
    • Phenotypic modulation by Legionella pneumophila upon infection of macrophages
    • Abu Kwaik, Y., B. I. Eisenstein, and N. C. Engleberg. 1993. Phenotypic modulation by Legionella pneumophila upon infection of macrophages. Infect. Immun. 61:1320-1329.
    • (1993) Infect. Immun. , vol.61 , pp. 1320-1329
    • Abu Kwaik, Y.1    Eisenstein, B.I.2    Engleberg, N.C.3
  • 4
    • 0028348039 scopus 로고
    • Protein expression by the protozoan Hartmannella vermiformis upon contact with its bacterial parasite Legionella pneumophila
    • Abu Kwaik, Y., B. S. Fields, and N. C. Engleberg. 1994. Protein expression by the protozoan Hartmannella vermiformis upon contact with its bacterial parasite Legionella pneumophila. Infect. Immun. 62:1860-1866.
    • (1994) Infect. Immun. , vol.62 , pp. 1860-1866
    • Abu Kwaik, Y.1    Fields, B.S.2    Engleberg, N.C.3
  • 5
    • 0345612100 scopus 로고    scopus 로고
    • Transcriptional regulation of the macrophage-induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant
    • Abu Kwaik, Y., L.-Y. Gao, O. S. Harb, and B. J. Stone. 1997. Transcriptional regulation of the macrophage-induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant. Mol. Microbiol. 24:629-642.
    • (1997) Mol. Microbiol. , vol.24 , pp. 629-642
    • Abu Kwaik, Y.1    Gao, L.-Y.2    Harb, O.S.3    Stone, B.J.4
  • 6
    • 0345612098 scopus 로고    scopus 로고
    • The use of differential display-PCR to isolate and characterize a Legionella pneumophila locus induced during the intracellular infection of macrophages
    • Abu Kwaik, Y., and L. L. Pederson. 1996. The use of differential display-PCR to isolate and characterize a Legionella pneumophila locus induced during the intracellular infection of macrophages. Mol. Microbiol. 21:543-556.
    • (1996) Mol. Microbiol. , vol.21 , pp. 543-556
    • Abu Kwaik, Y.1    Pederson, L.L.2
  • 7
    • 0026680572 scopus 로고
    • PhoA gene fusions in Legionella pneumophila generated in vivo using a new transposon, MudphoA
    • Albano, A. A., J. Arroyo, B. I. Eisenstein, and N. C. Engleberg. 1992. PhoA gene fusions in Legionella pneumophila generated in vivo using a new transposon, MudphoA. Mol. Microbiol. 6:1829-1839.
    • (1992) Mol. Microbiol. , vol.6 , pp. 1829-1839
    • Albano, A.A.1    Arroyo, J.2    Eisenstein, B.I.3    Engleberg, N.C.4
  • 8
    • 0020534178 scopus 로고
    • Peptidoglycan of Legionella pneumophila: Apparent resistance to lysozyme hydrolysis correlates with a high degree of peptide cross-linking
    • Amano, K.-I., and J. C. Williams. 1983. Peptidoglycan of Legionella pneumophila: apparent resistance to lysozyme hydrolysis correlates with a high degree of peptide cross-linking. J. Bacteriol. 153:520-526.
    • (1983) J. Bacteriol. , vol.153 , pp. 520-526
    • Amano, K.-I.1    Williams, J.C.2
  • 9
    • 0027956315 scopus 로고
    • Shuttle mutagencsis of Legionella pneumophila: Identification of a gene associated with host cell cytopathicity
    • Arroyo, J., M. C. Hurley, M. Wolf, M. S. McClain, B. I. Eisenstein, and N. C. Engleberg. 1994. Shuttle mutagencsis of Legionella pneumophila: identification of a gene associated with host cell cytopathicity. Infect. Immun. 62: 4075-4080.
    • (1994) Infect. Immun. , vol.62 , pp. 4075-4080
    • Arroyo, J.1    Hurley, M.C.2    Wolf, M.3    McClain, M.S.4    Eisenstein, B.I.5    Engleberg, N.C.6
  • 10
    • 0029944435 scopus 로고    scopus 로고
    • Leucine auxotrophy restricts the growth of Mycobacteriuin bovis BCG in macrophages
    • Bange, F., A. M. Brown, and W. R. Jacobs, Jr. 1996. Leucine auxotrophy restricts the growth of Mycobacteriuin bovis BCG in macrophages. Infect. Immun. 64:1794-1799.
    • (1996) Infect. Immun. , vol.64 , pp. 1794-1799
    • Bange, F.1    Brown, A.M.2    Jacobs Jr., W.R.3
  • 11
    • 0028785518 scopus 로고
    • Intraphagocytic growth induces an antibiotic-resistant phenotype of Legionella pneumophila
    • Barker, J., H. Scaife, and M. R. W. Brown. 1995. Intraphagocytic growth induces an antibiotic-resistant phenotype of Legionella pneumophila. Antimicrob. Agents Chemother. 39:2684-2688.
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 2684-2688
    • Barker, J.1    Scaife, H.2    Brown, M.R.W.3
  • 12
    • 0018875146 scopus 로고
    • Asparlate-β-semialdehyde dehydrogenase from Escherichia coli purification and general properties
    • Biellmann, J., P. Eid, C. Hirth, and H. Jornvall. 1980. Asparlate-β-semialdehyde dehydrogenase from Escherichia coli purification and general properties. Eur. J. Biochem. 104:53-58.
    • (1980) Eur. J. Biochem. , vol.104 , pp. 53-58
    • Biellmann, J.1    Eid, P.2    Hirth, C.3    Jornvall, H.4
  • 13
    • 0030033030 scopus 로고    scopus 로고
    • Interaction of Legionella pneumophila with Acanthamoeba castellanii: Uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion
    • Bozue, J. A., and W. Johnson. 1996. Interaction of Legionella pneumophila With Acanthamoeba castellanii: uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion. Infect. Immun. 64:668-673.
    • (1996) Infect. Immun. , vol.64 , pp. 668-673
    • Bozue, J.A.1    Johnson, W.2
  • 14
    • 0028807632 scopus 로고
    • Prevalence of pneumonia due to Legionella pneumophila and Mycoplasma pneumoniae in a population admitted to a department of internal medicine
    • Bozzoni, M., L. Radice, A. Frosi, S. Vezzoli, A. Cuboni, and F. Vezzoli. 1995. Prevalence of pneumonia due to Legionella pneumophila and Mycoplasma pneumoniae in a population admitted to a department of internal medicine. Respiration 62:331-335.
    • (1995) Respiration , vol.62 , pp. 331-335
    • Bozzoni, M.1    Radice, L.2    Frosi, A.3    Vezzoli, S.4    Cuboni, A.5    Vezzoli, F.6
  • 15
    • 0030990845 scopus 로고    scopus 로고
    • Specific detection of Salmonella typhimurium proteins synthesized intracellularly
    • Burns-Keliher, L. L., A. Portteus, and R. Curtiss III. 1997. Specific detection of Salmonella typhimurium proteins synthesized intracellularly. J. Bacteriol. 179:3604-3612.
    • (1997) J. Bacteriol. , vol.179 , pp. 3604-3612
    • Burns-Keliher, L.L.1    Portteus, A.2    Curtiss III, R.3
  • 16
    • 0024208699 scopus 로고
    • Site-specific mutagenesis in Legionella pneumophila by allelic exchange using counterselectable ColE1 vectors
    • Cianciotto, N. P., R. Long, B. I. Eisenstein, and N. C. Engleberg. 1988. Site-specific mutagenesis in Legionella pneumophila by allelic exchange using counterselectable ColE1 vectors. FEMS Microbiol. Lett. 56:203-208.
    • (1988) FEMS Microbiol. Lett. , vol.56 , pp. 203-208
    • Cianciotto, N.P.1    Long, R.2    Eisenstein, B.I.3    Engleberg, N.C.4
  • 17
    • 0027155664 scopus 로고
    • Legionnaires' disease
    • Edelstein, P. H. 1993. Legionnaires' disease. Clin. Infect. Dis. 16:741-749.
    • (1993) Clin. Infect. Dis. , vol.16 , pp. 741-749
    • Edelstein, P.H.1
  • 18
    • 0030200018 scopus 로고    scopus 로고
    • The molecular ecology of legionellae
    • Fields, B. S. 1996. The molecular ecology of legionellae. Trends Microbiol. 4:286-290.
    • (1996) Trends Microbiol. , vol.4 , pp. 286-290
    • Fields, B.S.1
  • 19
    • 0025608576 scopus 로고
    • Characterization of an axenic strain of Hartmannella vermiformis obtained from an investigation of nosocomial legionellosis
    • Fields, B. S., T. A. Nerad, T. K. Sawyer, C. H. King, J. M. Barbaree, W. T. Martin, W. E. Morrill, and G. N. Sanden. 1990. Characterization of an axenic strain of Hartmannella vermiformis obtained from an investigation of nosocomial legionellosis. J. Protozool. 37:581-583.
    • (1990) J. Protozool. , vol.37 , pp. 581-583
    • Fields, B.S.1    Nerad, T.A.2    Sawyer, T.K.3    King, C.H.4    Barbaree, J.M.5    Martin, W.T.6    Morrill, W.E.7    Sanden, G.N.8
  • 20
    • 0011736531 scopus 로고
    • Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
    • Fields, P. I., R. V. Swanson, C. G. Haidaris, and F. Heffron. 1986. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc. Natl. Acad. Sci. USA 83:5189-5193 .
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5189-5193
    • Fields, P.I.1    Swanson, R.V.2    Haidaris, C.G.3    Heffron, F.4
  • 21
    • 0030833998 scopus 로고    scopus 로고
    • Utilization of similar mechanisms by Legionella pneumophila to parasitize two evolutionarily distant hosts, mammalian and protozoan cells
    • Gao, L.-V., O. S. Harb, and Y. Abu Kwaik. 1997. Utilization of similar mechanisms by Legionella pneumophila to parasitize two evolutionarily distant hosts, mammalian and protozoan cells. Infect. Immun. 65:4738-4746.
    • (1997) Infect. Immun. , vol.65 , pp. 4738-4746
    • Gao, L.-V.1    Harb, O.S.2    Abu Kwaik, Y.3
  • 22
    • 0031951819 scopus 로고    scopus 로고
    • Identification of macrophage-specific infectivity loci (mil) of Legionella pneumophila that are not required for infectivity of protozoa
    • Gao, L.-Y., O. S. Harb, and Y. Abu Kwaik. 1998. Identification of macrophage-specific infectivity loci (mil) of Legionella pneumophila that are not required for infectivity of protozoa. Infect. Immun. 66:883-892.
    • (1998) Infect. Immun. , vol.66 , pp. 883-892
    • Gao, L.-Y.1    Harb, O.S.2    Abu Kwaik, Y.3
  • 24
    • 0018689273 scopus 로고
    • Identification of diaminopimelic acid in the Legionnaires' disease bacterium
    • Guerrant, G. O., M. S. Lambart, and C. W. Moss. 1979. Identification of diaminopimelic acid in the Legionnaires' disease bacterium. J. Clin. Microbiol. 10:815-818.
    • (1979) J. Clin. Microbiol. , vol.10 , pp. 815-818
    • Guerrant, G.O.1    Lambart, M.S.2    Moss, C.W.3
  • 25
    • 0031985851 scopus 로고    scopus 로고
    • Heterogeneity in the attachment and uptake mechanisms of the Legionnaires' disease bacterium, Legionella pneumophila, by protozoan hosts
    • Harb, O. S., C. Venkataraman, B. J. Haack, L.-Y. Gao, and Y. Abu Kwaik. 1998. Heterogeneity in the attachment and uptake mechanisms of the Legionnaires' disease bacterium, Legionella pneumophila, by protozoan hosts. Appl. Environ. Microbiol. 64:126-132.
    • (1998) Appl. Environ. Microbiol. , vol.64 , pp. 126-132
    • Harb, O.S.1    Venkataraman, C.2    Haack, B.J.3    Gao, L.-Y.4    Abu Kwaik, Y.5
  • 26
    • 0021253525 scopus 로고
    • Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing
    • Henikoff, S. 1984. Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. Gene 28:351-359.
    • (1984) Gene , vol.28 , pp. 351-359
    • Henikoff, S.1
  • 27
    • 0027218434 scopus 로고
    • Vaccination strategies against intracellular microbes
    • Hess, J., and H. E. Kaufmann. 1993. Vaccination strategies against intracellular microbes. FEMS Immunol. Med. Microhiol. 7:95-104.
    • (1993) FEMS Immunol. Med. Microhiol. , vol.7 , pp. 95-104
    • Hess, J.1    Kaufmann, H.E.2
  • 28
    • 0019407618 scopus 로고
    • Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
    • Hoiseth, S. K., and B. A. D. Stocker. 1981. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature 291:238-239.
    • (1981) Nature , vol.291 , pp. 238-239
    • Hoiseth, S.K.1    Stocker, B.A.D.2
  • 29
    • 0020591330 scopus 로고
    • Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes
    • Horwitz, M. A. 1983. Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J. Exp. Med. 158:1319-1331.
    • (1983) J. Exp. Med. , vol.158 , pp. 1319-1331
    • Horwitz, M.A.1
  • 30
    • 0027462422 scopus 로고
    • Immunity to intracellular bacteria
    • Kaufmann, S. H. E. 1993. Immunity to intracellular bacteria. Annu. Rev. Immunol. 11:129-163.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 129-163
    • Kaufmann, S.H.E.1
  • 31
    • 0026061006 scopus 로고
    • Effects of cytochalasin D and methylamine on intracellular growth of Legionella pneumophila in amoebae and human monocyte-like cells
    • King, C. H., B. S. Fields, E. B. Shotts, Jr., and E. H. White. 1991. Effects of cytochalasin D and methylamine on intracellular growth of Legionella pneumophila in amoebae and human monocyte-like cells. Infect. Immun. 59:758-763.
    • (1991) Infect. Immun. , vol.59 , pp. 758-763
    • King, C.H.1    Fields, B.S.2    Shotts Jr., E.B.3    White, E.H.4
  • 32
    • 0029586825 scopus 로고
    • Epidemiology of community-acquired pneumonia
    • Marston, B. J. 1995. Epidemiology of community-acquired pneumonia. Infect. Dis. Clin. Pract 4:S232-S239.
    • (1995) Infect. Dis. Clin. Pract , vol.4
    • Marston, B.J.1
  • 33
    • 0023906750 scopus 로고
    • Isolation and characterization of auxotrophic mutants of Legionella pneumophila that fail to multiply in human monocytes
    • Mintz, C. S., C. Jianxing, and H. A. Shuman. 1988. Isolation and characterization of auxotrophic mutants of Legionella pneumophila that fail to multiply in human monocytes. Infect. Immun. 56:1449-1455.
    • (1988) Infect. Immun. , vol.56 , pp. 1449-1455
    • Mintz, C.S.1    Jianxing, C.2    Shuman, H.A.3
  • 34
    • 0021840153 scopus 로고
    • Adhesion, penetration and intracellular replication of Legionella pneumophila: An in vitro model of pathogencsis
    • Oldham, L. J., and F. G. Rodgers. 1985. Adhesion, penetration and intracellular replication of Legionella pneumophila: an in vitro model of pathogencsis. J. Gen. Microbiol. 131:697-706.
    • (1985) J. Gen. Microbiol. , vol.131 , pp. 697-706
    • Oldham, L.J.1    Rodgers, F.G.2
  • 35
    • 0030738990 scopus 로고    scopus 로고
    • Lack of resistance to erythromycin, rifampicin and ciprofloxacin in 98 clinical isolates of Legionella pneumophila
    • Onody, C., P. Matsiota-Bernard, and C. Nauciel. 1997. Lack of resistance to erythromycin, rifampicin and ciprofloxacin in 98 clinical isolates of Legionella pneumophila. J. Antimicrob. Chemother. 39:815-816.
    • (1997) J. Antimicrob. Chemother. , vol.39 , pp. 815-816
    • Onody, C.1    Matsiota-Bernard, P.2    Nauciel, C.3
  • 36
    • 0029041303 scopus 로고
    • Use of structural comparisons to select mutagenic targets in aspartate-β-semialdchyde dehydrogenase
    • Ouvang, J., and R. E. Viola. 1995. Use of structural comparisons to select mutagenic targets in aspartate-β-semialdchyde dehydrogenase. Biochemistry 34:6394-6399.
    • (1995) Biochemistry , vol.34 , pp. 6394-6399
    • Ouvang, J.1    Viola, R.E.2
  • 37
    • 0001592640 scopus 로고
    • A unidirectional deletion technique for the generation of clones for sequencing
    • Ozkaynak, E., and S. D. Putney. 1987. A unidirectional deletion technique for the generation of clones for sequencing. BioTechniques 5:770-773.
    • (1987) BioTechniques , vol.5 , pp. 770-773
    • Ozkaynak, E.1    Putney, S.D.2
  • 38
    • 10344230938 scopus 로고    scopus 로고
    • Biosynthesis of diaminopimelate, the precursor of lysine and a component of peplidoglycan, is an essential function of Mycobacterium smegmatis
    • Pavelka, M. S., Jr., and W. R. Jacobs, Jr. 1996. Biosynthesis of diaminopimelate, the precursor of lysine and a component of peplidoglycan, is an essential function of Mycobacterium smegmatis. J. Bacteriol. 178:6496-6507.
    • (1996) J. Bacteriol. , vol.178 , pp. 6496-6507
    • Pavelka Jr., M.S.1    Jacobs Jr., W.R.2
  • 41
    • 0032036425 scopus 로고    scopus 로고
    • Expression of multiple pili by Legionella pneumophila: Identification and characterization of a type IV pilin gene and its role in adherence to mammalian and protozoan cells
    • Stone, B. J., and Y. Abu Kwaik. 1998. Expression of multiple pili by Legionella pneumophila: identification and characterization of a type IV pilin gene and its role in adherence to mammalian and protozoan cells. Infect. Immun. 66:1768-1775.
    • (1998) Infect. Immun. , vol.66 , pp. 1768-1775
    • Stone, B.J.1    Abu Kwaik, Y.2
  • 42
    • 0029944643 scopus 로고    scopus 로고
    • Dc novo synthesis of Legionella pneumophila antigens during intracellular growth in phagocytic cells
    • Susa, M., J. Hacker, and R. Marre. 1996. Dc novo synthesis of Legionella pneumophila antigens during intracellular growth in phagocytic cells. Infect. Immun. 64:1679-1684.
    • (1996) Infect. Immun. , vol.64 , pp. 1679-1684
    • Susa, M.1    Hacker, J.2    Marre, R.3
  • 43
    • 0028802446 scopus 로고
    • Emerging problems in antimicrobial resistance
    • Tenover, F. C. 1995. Emerging problems in antimicrobial resistance. J. Intraven. Nurs. 18:297-300.
    • (1995) J. Intraven. Nurs. , vol.18 , pp. 297-300
    • Tenover, F.C.1
  • 44
    • 0017794395 scopus 로고
    • Amino acid biosynthesis and its regulation
    • Umbarger, H. E. 1978. Amino acid biosynthesis and its regulation. Annu. Rev. Biochem. 47:533-606.
    • (1978) Annu. Rev. Biochem. , vol.47 , pp. 533-606
    • Umbarger, H.E.1
  • 45
    • 0030750209 scopus 로고    scopus 로고
    • Identification of a Gal/GalNAc lectin in the protozoan Hartmanella vermiformis as a potential receptor for attachment and invasion by the Legionnaires' disease bacterium, Legionella pneumophila
    • Venkataraman, C., B. J. Haack, S. Bondada, and Y. Abu Kwaik. 1997. Identification of a Gal/GalNAc lectin in the protozoan Hartmanella vermiformis as a potential receptor for attachment and invasion by the Legionnaires' disease bacterium, Legionella pneumophila. J. Exp. Med. 186:537-547.
    • (1997) J. Exp. Med. , vol.186 , pp. 537-547
    • Venkataraman, C.1    Haack, B.J.2    Bondada, S.3    Abu Kwaik, Y.4


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