Effect of lanreotide on local kidney IGF-I and renal growth in experimental diabetes in the rat

Experimental Nephrology

Volumn 4, Issue 5, 1996, Pages 295-303

  Grønbæk, Henning ^a   Nielsen, Birgitte ^a   Frystyk, Jan ^a   Flyvbjerg, Allan ^a   Ørskov, Hans ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Experimental diabetes, rats; IGF I; Lanreotide; Renal growth; Somatostatin analogue

Indexed keywords

ANGIOPEPTIN; INSULIN; INSULIN ZINC SUSPENSION; SOMATOMEDIN; SOMATOSTATIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; KIDNEY HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DNA; HYPERTROPHY; INSULIN; INSULIN-LIKE GROWTH FACTOR I; KIDNEY; KIDNEY CORTEX; KIDNEY GLOMERULUS; KIDNEY MEDULLA; MALE; ORGAN SIZE; PEPTIDES, CYCLIC; PROTEINS; RATS; RATS, WISTAR; SOMATOSTATIN;

EID: 0029803052     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Flyvbjerg A, Thorlacius-Ussing O, Næraa R, Ingerslev J, Yrskov H: Kidney tissue somatomedin C and initial renal growth in diabetic and uninephrectomized rats. Diabetologia 1988;31:310-314.
2. Flyvbjerg A, Mogensen CE, Østerby R, Ørskov H: Renal hypertrophy in experimental diabetes. J Diabetes Complications 1991;5:62-64.
3. Flyvbjerg A, Frystyk J, Thorlacius-Ussing O, Ørskov H: Somatostatin analogue administration prevents increase in kidney somatomedin C and initial renal growth in diabetic and uninephrectomized rats. Diabetologia 1989;32: 261-265.
4. Landau D, Chin E, Bondy C, Domene H, Roberts CT, Grønbæk H, Flyvbjerg A, LeRoith D: Expression of insulin-like growth factor binding proteins in the rat kidney: Effects of long-term diabetes. Endocrinology 1995;136: 1835-1842.
5. Andersson GL, Skottner A, Jennische E: Immunocytochemical and biochemical localization of insulin-like growth factor I in the kidney of rats before and after uninephrectomy. Acta Endocrinol (Copenh) 1988;119:555-560.
6. Flyvbjerg A: The role of insulin-like growth factor I in initial renal hypertrophy in experimental diabetes; in Flyvbjerg A, Ørskov H, Alberti KGMM (eds): Growth Hormone and Insulin-like Growth Factor I in Human and Experimental Diabetes. Chichester, Wiley, 1993, pp 271-306.
7. Grønbæk H, Nilsen B, Østerby R, Harris AG, Øskov H, Flyvbjerg A: Effect of octreotide and insulin on manifest renal and glomerular hypertrophy and urinary albumin excretion in long-term experimental diabetes in rats. Diabetologia 1995;2:135-144.
8. Ørskov H, Flyvbjerg A, Frystyk J, Grønbæk H, Foegh M, Harris AG: IGF-1 and acute renal hypertrophy: Inhibition by somatostatin analogues. Transplant Proc 1993;25:2061-2062.
9. Seyer-Hansen K, Hansen J, Gundersen HJG: Renal hypertrophy in experimental diabetes: A morphometric study. Diabetologia 1980;18: 501-505.
10. Flyvbjerg A: The growth hormone/insulin-like growth factor axis in the kidney: Aspects in relation to chronic renal failure. J Pediatr Endocrinol 1994;7:85-92.
11. Gundersen HJG, Bagger P, Bendtsen TF, Evans SM, Korbo L, Marcussen N, Møller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A, West MJ: The new stereological tools: Dissector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 1988;96:857-881.
12. Gundersen HJG, Bendtsen TF, Korbo L, Marcussen N, Möller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sørensen FB, Vesterby A, West MJ: Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 1988;96:379-394.
13. D'Ereole AJ, Stiles AD, Underwood LE: Tissue concentrations of somatomedin C: Further evidence for multiple sites of synthesis and paracrine our autocrine mechanisms of action. Proc Natl Acad Sci USA 1984;81:935-939.
14. Grønbæk H, Frystyk J, Ørskov H, Flyvbjerg A: Effect of sodium selenite on growth, insulin-like growth factor binding proteins, and insulin-like growth factor I in rats. J Endocrinol 1995;145:105-112.
15. Lowry OH, Rosebrough NJ, Farr AL, Randall RL: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:165-175.
16. LaBarca C, Paigen K: A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 1980;102:344-352.
17. Flyvbjerg A, Frystyk J, Østerby R, Ørskov H: Kidney IGF-I and renal hypertrophy in GH-deficient diabetic dwarf rats. Am J Physiol 1992;262:E956-E962.
18. Flyvberg A, Ørskov H: Kidney tissue insulin-like growth factor I and initial renal growth in diabetic rats: Relation to severity of diabetes. Acta Endocrinol (Copenh) 1990;122:374-378.
19. Flyvbjerg A, Bornfeldt KE, Marshall SM, Arnqvist HJ, Ørskov H: Kidney IGF-I mRNA in initial renal hypertrophy in experimental diabetes in rats. Diabetologia 1990;33:334-338.
20. Bach LA, Stevenson JL, Allen TJ, Jerums G, Herington AC: Kidney insulin-like growth factor-I mRNA levels are increased in postpubertal diabetic rats. J Endocrinol 1991;129:5-10.
21. De Vroede MA, Tseng LY, Katsoyannis PG, Nissley SP, Rechler MM: Modulation of insulin-like growth factor I binding to human fibroblast monolayer cultures by insulin-like growth factor carrier proteins released to the incubation media. J Clin Invest 1986;77:602-613.
22. Jones JI, Gockerman A, Busby WH, Jr, Wright G, Clemmons DR: Insulin-like growth factor 1 binding protein stimulates cell migration and binds to the a5b1 integrin by means of its ArgGly-Asp sequence. Proc Natl Acad Sci USA 1993;90:10553-10557.
23. Flyvbjerg A, Kessler U, Dorka B, Funk B, Ørskov H, Kiess W: Transient increase in renal insulin-like growth factor binding proteins during initial kidney hypertrophy in experimental diabetes in rats. Diabetologia 1992;35:589-593.
24. Bortz JD, Rotwein P, DeVol D, Bechtel PJ, Hansen VA, Hammerman MR: Focal expression of insulin-like growth factor I in rat kidney collecting duct. J Cell Biol 1988;107:811-819.
25. Grønbæk H, Flyvbjerg A, Foegh ML, Ørskov H: The effect of angiopeptin, a somatostatin analogue, on circulating IGFBPs and initial renal hypertrophy in experimental diabetes in rats (abstract). 4th Int Symp on Insulin, IGFs, and Their Receptors, Woods Hole, 1993.
26. Weiss O, Rubinger D, Nephesh I, Moshe R, Raz I: The influence of octreotide on IGF system gene expression in the kidney of diabetic rats (abstract). Diabetologia 1995;38:206.
27. Vora J, Owens DR, Luzio SD, Atiea J, Ryder R, Hayes TM: Renal response to intravenous somatostatin in insulin-dependent diabetic patients and normal subjects. J Clin Endocrinol Metab 1987;64:975-979.
28. Pedersen MM, Christensen SE, Christiansen JS, Pedersen EB, Mogensen CE, Ørskov H: Acute effects of a somatostatin analogue on kidney function in type 1 diabetic patients. Diabetic Med 1990;7:304-309.
29. Serri O, Beauregard H, Brazeau P, Abribat T, Lambert J, Harris A, Vachon L: Somatostatin analogue, octreotide, reduces increased glomerular filtration rate and kidney size in insulin-dependent diabetes. JAMA 1991;265:888-892.
30. Hirschberg RR, Kopple JD: Increase in renal plasma flow and glomerular filtration rate during growth hormone treatment may be mediated by insulin-like growth factor I. Am J Nephrol 1988;8:249-254.
31. Flyvbjerg A, Marshall SM, Frystyk J, Hansen KW, Harris AG, Ørskov H: Octreotide administration in diabetic rats: Effects on renal hypertrophy and urinary albumin excretion. Kidney Int 1992;41:805-812.
32. Seyer-Hansen K: Renal hypertrophy in experimental diabetes: Relation to severity of diabetes. Diabetologia 1977;13:141-143.
33. Grønbæk H, Nielsen B, Frystyk J, Ørskov H, Flyvbjerg A: Effect of octreotide on experimental diabetic renal and glomerular growth: Importance of early intervention. J Endocrinol 1995;147:95-102.
34. Seyer-Hansen K: Renal hypertrophy in streptozotocin diabetic rats. Clin Sci Mol Med 1976; 51:551-555.