메뉴 건너뛰기




Volumn 92, Issue 6, 1998, Pages 795-809

Leukotriene antagonism in asthma and rhinitis

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; LEUKOTRIENE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; PRANLUKAST; ZAFIRLUKAST; ZILEUTON;

EID: 0031876485     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0954-6111(98)90380-8     Document Type: Review
Times cited : (21)

References (150)
  • 1
    • 0003384466 scopus 로고
    • Allergic rhinitis
    • Busse WW, Holgate ST, eds. Oxford, U.K.: Blackwell Scientific
    • Creticos P. Allergic rhinitis. In: Busse WW, Holgate ST, eds. Asthma and Rhinitis. Oxford, U.K.: Blackwell Scientific, 1995; 1394-1414.
    • (1995) Asthma and Rhinitis , pp. 1394-1414
    • Creticos, P.1
  • 2
    • 0027497746 scopus 로고
    • Treatment of allergic rhinitis with intranasal corticosteroids in patients with mild asthma: Effect on lower airways responsiveness
    • Watson WTA, Becker AB, Simons FER. Treatment of allergic rhinitis with intranasal corticosteroids in patients with mild asthma: effect on lower airways responsiveness. J Allergy Clin Immunol 1993; 91: 97-101.
    • (1993) J Allergy Clin Immunol , vol.91 , pp. 97-101
    • Watson, W.T.A.1    Becker, A.B.2    Simons, F.E.R.3
  • 3
    • 0023500861 scopus 로고
    • Asthma, asthma-like symptoms, chronic bronchitis and the degree of bronchial hyperresponsiveness in epidemiological surveys
    • Enarson DA, Vedal S, Schulzer M, Chan-Yeung M. Asthma, asthma-like symptoms, chronic bronchitis and the degree of bronchial hyperresponsiveness in epidemiological surveys. Am Rev Respir Dis 1987; 136: 613-617.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 613-617
    • Enarson, D.A.1    Vedal, S.2    Schulzer, M.3    Chan-Yeung, M.4
  • 9
    • 0028956973 scopus 로고
    • Drug therapy - Inhaled glucocorticoids for asthma
    • Barnes PJ. Drug therapy - inhaled glucocorticoids for asthma. N Engl J Med 1995; 332: 868-875
    • (1995) N Engl J Med , vol.332 , pp. 868-875
    • Barnes, P.J.1
  • 10
    • 0002956172 scopus 로고
    • International report on the diagnosis and management of rhinitis
    • International Rhinitis Working Group. International report on the diagnosis and management of rhinitis. Allergy 1994; 49 (Suppl): s1-s34.
    • (1994) Allergy , vol.49 , Issue.SUPPL.
  • 11
    • 0031024694 scopus 로고    scopus 로고
    • Effects of montelukast (MK-0476), a potent cysteinyl leukotriene receptor antagonist, on bronchodilation in asthmatic subjects treated with and without inhaled corticosteroids
    • Reiss TF, Sorkness CA, Stricker W et al. Effects of montelukast (MK-0476), a potent cysteinyl leukotriene receptor antagonist, on bronchodilation in asthmatic subjects treated with and without inhaled corticosteroids. Thorax 1997; 52: 45-48.
    • (1997) Thorax , vol.52 , pp. 45-48
    • Reiss, T.F.1    Sorkness, C.A.2    Stricker, W.3
  • 12
    • 84980124399 scopus 로고
    • The liberation of a slow reacting smooth muscle stimulating substance of anaphylaxis
    • Kelleway CH, Trethewie WR. The liberation of a slow reacting smooth muscle stimulating substance of anaphylaxis. Quart J Exp Physiol 1940; 30: 124-145.
    • (1940) Quart J Exp Physiol , vol.30 , pp. 124-145
    • Kelleway, C.H.1    Trethewie, W.R.2
  • 13
    • 0019314753 scopus 로고
    • Structure of slow reacting substance of anaphylaxis from guinea pig lung
    • Morris HR, Taylor GW, Piper PJ. Structure of slow reacting substance of anaphylaxis from guinea pig lung. Nature 1980; 285: 104-106.
    • (1980) Nature , vol.285 , pp. 104-106
    • Morris, H.R.1    Taylor, G.W.2    Piper, P.J.3
  • 14
    • 0019308374 scopus 로고
    • Slow reacting substance of anaphylaxis: Identification of leukotriene C-1 and D from human and rat sources
    • Lewis RA. Austen KF, Drazen JM. Slow reacting substance of anaphylaxis: identification of leukotriene C-1 and D from human and rat sources. Proc Natl Acad Sci U.S.A. 1980; 77: 3712-3714.
    • (1980) Proc Natl Acad Sci U.S.A. , vol.77 , pp. 3712-3714
    • Lewis, R.A.1    Austen, K.F.2    Drazen, J.M.3
  • 15
    • 0018837606 scopus 로고
    • Leukotrienes and slow reacting substance of anaphylaxis (SRS-A)
    • Samuelsson B, Hammarstrom S, Murphy RC. Leukotrienes and slow reacting substance of anaphylaxis (SRS-A). Allergy 1980; 35: 375-381.
    • (1980) Allergy , vol.35 , pp. 375-381
    • Samuelsson, B.1    Hammarstrom, S.2    Murphy, R.C.3
  • 16
    • 13144252822 scopus 로고    scopus 로고
    • Lipid mediators - Leukotrienes, Prostanoids and platelet activating factor
    • Kay AB, ed. Oxford: Blackwell Science
    • Nasser SN, Lee TH. Lipid mediators - Leukotrienes, Prostanoids and platelet activating factor. In: Kay AB, ed. Allergy and Allergic Diseases. Oxford: Blackwell Science, 1996: 380-418.
    • (1996) Allergy and Allergic Diseases , pp. 380-418
    • Nasser, S.N.1    Lee, T.H.2
  • 17
    • 0025022489 scopus 로고
    • Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
    • Dixon RAF, Diehl RE, Opas E. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 1990; 343: 282-284.
    • (1990) Nature , vol.343 , pp. 282-284
    • Dixon, R.A.F.1    Diehl, R.E.2    Opas, E.3
  • 18
    • 0027243266 scopus 로고
    • Leukotriene synthesis in U937 cells expressing recombinant 5-lipoxygenase
    • Kargman S, Rousseau P, Reid GK. Leukotriene synthesis in U937 cells expressing recombinant 5-lipoxygenase. J Lipid Mediators 1993; 7: 31-35.
    • (1993) J Lipid Mediators , vol.7 , pp. 31-35
    • Kargman, S.1    Rousseau, P.2    Reid, G.K.3
  • 19
    • 0021248579 scopus 로고
    • Release of leukotrienes by human monocytes on stimulation of their phagocytic receptor for particulate activators
    • Williams JD, Czop JK, Austen KF. Release of leukotrienes by human monocytes on stimulation of their phagocytic receptor for particulate activators. J Immunol 1984; 132: 3034-3040.
    • (1984) J Immunol , vol.132 , pp. 3034-3040
    • Williams, J.D.1    Czop, J.K.2    Austen, K.F.3
  • 20
    • 0009477876 scopus 로고
    • Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: Predominant production of leukotriene C4
    • Weller PF, Lee CW, Foster DW, Corey EJ, Austen KF, Lewis RA. Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4. Proc Natl Acad Sci U.S.A. 1983; 80: 7626-7630.
    • (1983) Proc Natl Acad Sci U.S.A. , vol.80 , pp. 7626-7630
    • Weller, P.F.1    Lee, C.W.2    Foster, D.W.3    Corey, E.J.4    Austen, K.F.5    Lewis, R.A.6
  • 21
    • 0022878291 scopus 로고
    • Endothelial cell leukotriene C4 synthesis results from intercellular transfer of leukotriene A4 synthesized by polymorphonuclear leukocytes
    • Feinmark SJ, Cannon PJ. Endothelial cell leukotriene C4 synthesis results from intercellular transfer of leukotriene A4 synthesized by polymorphonuclear leukocytes. J Biol Chem 1986; 261: 16466-16472.
    • (1986) J Biol Chem , vol.261 , pp. 16466-16472
    • Feinmark, S.J.1    Cannon, P.J.2
  • 22
    • 0029181674 scopus 로고
    • Prostanoid and leukotriene receptors - A progress report from the IUPHAR Working Parties on Classification and Nomenclature
    • Coleman RA, Eglen RM, Jones RL et al. Prostanoid and leukotriene receptors - a progress report from the IUPHAR Working Parties on Classification and Nomenclature. Adv Prostaglandin Thromboxane Leukotriene Res 1995; 23: 283-285.
    • (1995) Adv Prostaglandin Thromboxane Leukotriene Res , vol.23 , pp. 283-285
    • Coleman, R.A.1    Eglen, R.M.2    Jones, R.L.3
  • 23
    • 0000951027 scopus 로고
    • Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro
    • Drazen JM, Austen KF, Lewis RA. Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro. Proc Natl Acad Sci U.S.A. 1980; 77: 4354-4358.
    • (1980) Proc Natl Acad Sci U.S.A. , vol.77 , pp. 4354-4358
    • Drazen, J.M.1    Austen, K.F.2    Lewis, R.A.3
  • 24
    • 0021141207 scopus 로고
    • Selective transduction of human polymorphonuclear leukocyte functions by subsets of receptors for leukotriene B4
    • Goldman DW, Goetzl EJ. Selective transduction of human polymorphonuclear leukocyte functions by subsets of receptors for leukotriene B4. J Allergy Clin Immunol 1984; 74: 373-377.
    • (1984) J Allergy Clin Immunol , vol.74 , pp. 373-377
    • Goldman, D.W.1    Goetzl, E.J.2
  • 25
    • 0000747598 scopus 로고
    • Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: In vivo effects with relevance to the acute inflammatory response
    • Dahlén S-E, Björk J, Hedqvist P et al. Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci U.S.A. 1981; 78: 3887-3891.
    • (1981) Proc Natl Acad Sci U.S.A. , vol.78 , pp. 3887-3891
    • Dahlén, S.-E.1    Björk, J.2    Hedqvist, P.3
  • 26
    • 0022476645 scopus 로고
    • Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils
    • McIntyre TM, Zimmerman GA, Prescott SM. Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils. Proc Natl Acad Sci U.S.A. 1986; 83: 2204-2208.
    • (1986) Proc Natl Acad Sci U.S.A. , vol.83 , pp. 2204-2208
    • McIntyre, T.M.1    Zimmerman, G.A.2    Prescott, S.M.3
  • 28
    • 0019254822 scopus 로고
    • Leukotrienes are potent constrictors of human bronchi
    • Dahlen SE, Hedqvist P, Hammaarstrom SBS. Leukotrienes are potent constrictors of human bronchi. Nature 1980; 288: 484-486.
    • (1980) Nature , vol.288 , pp. 484-486
    • Dahlen, S.E.1    Hedqvist, P.2    Hammaarstrom, S.B.S.3
  • 29
    • 0022459317 scopus 로고
    • Airway responsiveness to leukotrienes C4 and D4 and to methacholine in patients with asthma and normal controls
    • Adelroth E, Morris MM, Hargreave FE, M OBP. Airway responsiveness to leukotrienes C4 and D4 and to methacholine in patients with asthma and normal controls. N Engl J Med 1986; 315: 480-484.
    • (1986) N Engl J Med , vol.315 , pp. 480-484
    • Adelroth, E.1    Morris, M.M.2    Hargreave, F.E.3    M, O.B.P.4
  • 30
    • 0023152470 scopus 로고
    • Bronchoconstrictor effects of leukotriene-E4 in normal and asthmatic subjects
    • Davidson AB, Lee TH, Scanlon PD et al. Bronchoconstrictor effects of leukotriene-E4 in normal and asthmatic subjects. Am Rev Respir Dis 1987; 135: 333-337.
    • (1987) Am Rev Respir Dis , vol.135 , pp. 333-337
    • Davidson, A.B.1    Lee, T.H.2    Scanlon, P.D.3
  • 31
    • 0021269295 scopus 로고
    • Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects
    • Barnes NC, Piper PJ, Costello JF. Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects. Thorax 1984; 39: 500-504.
    • (1984) Thorax , vol.39 , pp. 500-504
    • Barnes, N.C.1    Piper, P.J.2    Costello, J.F.3
  • 32
    • 0024242242 scopus 로고
    • The relative responsiveness to inhaled leukotriene-E4, methacholine and histamine in normal and asthmatic subjects
    • O'Hickey SP, Arm JP, Rees PJ, Spur BW, Lee TH. The relative responsiveness to inhaled leukotriene-E4, methacholine and histamine in normal and asthmatic subjects. Eur Resp J 1988; 1: 913-917.
    • (1988) Eur Resp J , vol.1 , pp. 913-917
    • O'Hickey, S.P.1    Arm, J.P.2    Rees, P.J.3    Spur, B.W.4    Lee, T.H.5
  • 34
    • 0022614879 scopus 로고
    • Characterization of the airway response to inhaled leukotriene D4 in normal subjects
    • Kern R, Smith LJ, Patterson R. Characterization of the airway response to inhaled leukotriene D4 in normal subjects. Am Rev Respir Dis 1986; 131: 1127-1132.
    • (1986) Am Rev Respir Dis , vol.131 , pp. 1127-1132
    • Kern, R.1    Smith, L.J.2    Patterson, R.3
  • 36
    • 0025925113 scopus 로고
    • Leuoktriene-C4, Leukotriene-D4, and leukotriene-E4 enhance histamine responsiveness in asthmatic airways
    • O'Hickey SP, Hawksworth RJ, Fong CY, Arm JP, Spur BW, Lee TH. Leuoktriene-C4, Leukotriene-D4, and leukotriene-E4 enhance histamine responsiveness in asthmatic airways. Am Rev Respir Dis 1991; 144: 1053-1057.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 1053-1057
    • O'Hickey, S.P.1    Hawksworth, R.J.2    Fong, C.Y.3    Arm, J.P.4    Spur, B.W.5    Lee, T.H.6
  • 37
    • 0026614209 scopus 로고
    • Effect of indomethacin on leukotriene E4-induced histamine hyperresponsiveness in asthmatic subjects
    • Christie PE, Hawksworth R, Spur BW, Lee TH. Effect of indomethacin on leukotriene E4-induced histamine hyperresponsiveness in asthmatic subjects. Am Rev Respir Dis 1992; 146: 1506-1510.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 1506-1510
    • Christie, P.E.1    Hawksworth, R.2    Spur, B.W.3    Lee, T.H.4
  • 40
    • 0025922730 scopus 로고
    • Urinary leukotriene E4 in patients with asthma. Effect of airways reactivity and sodium cromoglycate
    • Westcott JY, Smith HR, Wenzel SE, Larsen GL, Thomas RB, Felsien D. Urinary leukotriene E4 in patients with asthma. Effect of airways reactivity and sodium cromoglycate. Am Rev Respir Dis 1991; 143: 1322-1328.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 1322-1328
    • Westcott, J.Y.1    Smith, H.R.2    Wenzel, S.E.3    Larsen, G.L.4    Thomas, R.B.5    Felsien, D.6
  • 41
    • 0028181801 scopus 로고
    • Increased urinary LTE(4) excretion following inhalation of LTC(4) and LTE(4) in asthmatic subjects
    • Christie PE, Tagari P, Ford-Hutchinson AW et al. Increased urinary LTE(4) excretion following inhalation of LTC(4) and LTE(4) in asthmatic subjects. Eur Resp J 1994; 7: 907-913.
    • (1994) Eur Resp J , vol.7 , pp. 907-913
    • Christie, P.E.1    Tagari, P.2    Ford-Hutchinson, A.W.3
  • 42
    • 0025284206 scopus 로고
    • Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge
    • Wenzel SE, Larsen GL, Johnston K, Voelkel NF, Westcott JY. Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge. Am Rev Respir Dis 1990: 142: 112-119.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 112-119
    • Wenzel, S.E.1    Larsen, G.L.2    Johnston, K.3    Voelkel, N.F.4    Westcott, J.Y.5
  • 43
    • 0025819314 scopus 로고
    • Bronchoalveolar lavage fluid mediator levels 5 minutes after allergen challenge in atopic subjects with asthma: Relationship to the development of late asthmatic responses
    • Wenzel SE, Westcott JY, Larsen GL. Bronchoalveolar lavage fluid mediator levels 5 minutes after allergen challenge in atopic subjects with asthma: relationship to the development of late asthmatic responses. J Allergy Clin Immunol 1991; 87: 540-548.
    • (1991) J Allergy Clin Immunol , vol.87 , pp. 540-548
    • Wenzel, S.E.1    Westcott, J.Y.2    Larsen, G.L.3
  • 44
    • 0025194386 scopus 로고
    • Urinary leukotriene E4 levels during early and late asthmatic responses
    • Manning PJ, Rokach J, Malo JL et al. Urinary leukotriene E4 levels during early and late asthmatic responses. J Allergy Clin Immunol 1990; 86: 211-220.
    • (1990) J Allergy Clin Immunol , vol.86 , pp. 211-220
    • Manning, P.J.1    Rokach, J.2    Malo, J.L.3
  • 45
    • 0026644731 scopus 로고
    • Urinary excretion of leukotriene-E4 and 11-dehydro-thromboxane-B2 in response to bronchial provocations with allergen, aspirin, leukotriene-D4, and histamine in asthmatics
    • Kumlin M, Dahlen B, Bjorck T, Zetterstrom O, Granstrom E, Dahlen SE. Urinary excretion of leukotriene-E4 and 11-dehydro-thromboxane-B2 in response to bronchial provocations with allergen, aspirin, leukotriene-D4, and histamine in asthmatics. Am Rev Respir Dis 1992; 146: 96-103.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 96-103
    • Kumlin, M.1    Dahlen, B.2    Bjorck, T.3    Zetterstrom, O.4    Granstrom, E.5    Dahlen, S.E.6
  • 46
    • 0027938710 scopus 로고
    • Effect of the 5-lipoxygenase inhibitor ZD2138 on allergen-induced early and late asthmatic responses
    • Nasser SMS, Bell GS, Hawksworth RJ et al. Effect of the 5-lipoxygenase inhibitor ZD2138 on allergen-induced early and late asthmatic responses. Thorax 1994; 49: 743-748.
    • (1994) Thorax , vol.49 , pp. 743-748
    • Nasser, S.M.S.1    Bell, G.S.2    Hawksworth, R.J.3
  • 47
    • 0025279184 scopus 로고
    • Assessment of bronchoalveolar cell and mediator response to isocapnic hyperpnea in asthma
    • Pliss LB, Ingenito EP, Ingram RH Jr, Pichurko B. Assessment of bronchoalveolar cell and mediator response to isocapnic hyperpnea in asthma. Am Rev Respir Dis 1990; 142: 73-78.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 73-78
    • Pliss, L.B.1    Ingenito, E.P.2    Ingram Jr., R.H.3    Pichurko, B.4
  • 48
  • 49
    • 0026610949 scopus 로고
    • Urinary leukotriene E4 after exercise challenge in children with asthma
    • Kikawa Y, Miyanomae T, Inoue T et al. Urinary leukotriene E4 after exercise challenge in children with asthma. J Allergy Clin Immunol 1992; 89: 1111-1119.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 1111-1119
    • Kikawa, Y.1    Miyanomae, T.2    Inoue, T.3
  • 50
    • 0025892285 scopus 로고
    • Urinary leukotriene-E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects
    • Christie PE, Tagari P, Ford-Hutchinson AW, et al. Urinary leukotriene-E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. Am Rev Respir Dis 1991; 143: 1025-1029.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 1025-1029
    • Christie, P.E.1    Tagari, P.2    Ford-Hutchinson, A.W.3
  • 52
    • 0028274647 scopus 로고
    • Eicosanoids in bronchoalveolar lavage fluid of aspirin-tolerant patients with asthma after aspirin challenge
    • Sladek K, Dworski R, Soja J, Sheller JR, Nizankowska E, Oates JA. Eicosanoids in bronchoalveolar lavage fluid of aspirin-tolerant patients with asthma after aspirin challenge. Am J Respir Crit Care Med 1994; 149: 940-946.
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 940-946
    • Sladek, K.1    Dworski, R.2    Soja, J.3    Sheller, J.R.4    Nizankowska, E.5    Oates, J.A.6
  • 53
    • 0026542517 scopus 로고
    • Release of peptide leukotriene into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatic patients
    • Picado C, Ramis I, Rosello J et al. Release of peptide leukotriene into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatic patients. Am Rev Respir Dis 1992; 145: 65-69.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 65-69
    • Picado, C.1    Ramis, I.2    Rosello, J.3
  • 56
    • 0026613070 scopus 로고
    • Recovery of leukotriene-E4 from the urine of patients with airway obstruction
    • Drazen JM, O'Brien J, Sparrow D et al. Recovery of leukotriene-E4 from the urine of patients with airway obstruction. Am Rev Respir Dis 1992; 146: 104-108.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 104-108
    • Drazen, J.M.1    O'Brien, J.2    Sparrow, D.3
  • 57
    • 0025806375 scopus 로고
    • The role of leukotrienes in allergic rhinitis - A review
    • Naclerio RM, Baroody FM, Togias AG. The role of leukotrienes in allergic rhinitis - a review. Am Rev Respir Dis 1991; 143 (Suppl): S91-S95.
    • (1991) Am Rev Respir Dis , vol.143 , Issue.SUPPL.
    • Naclerio, R.M.1    Baroody, F.M.2    Togias, A.G.3
  • 58
    • 0023584473 scopus 로고
    • Behaviour and clinical relevance of histamine and leukotrienes C4 and B4 in grass pollen-induced rhinitis
    • Miadonna A, Tedeschi A, Leggieri E. Behaviour and clinical relevance of histamine and leukotrienes C4 and B4 in grass pollen-induced rhinitis. Am Rev Respir Dis 1987; 136: 357-62.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 357-362
    • Miadonna, A.1    Tedeschi, A.2    Leggieri, E.3
  • 59
    • 0021136478 scopus 로고
    • Peptide leukotriene release after antigen challenge in patients sensitive to ragweed
    • Creticos PS, Peters SP, Adkinson NF et al. Peptide leukotriene release after antigen challenge in patients sensitive to ragweed. N Eng J Med 1984; 310: 1626-1630.
    • (1984) N Eng J Med , vol.310 , pp. 1626-1630
    • Creticos, P.S.1    Peters, S.P.2    Adkinson, N.F.3
  • 60
    • 0026356690 scopus 로고
    • Nasal inflammatory mediator release in ragweed allergic rhinitis - Correlation with cellular influx into nasal secretions
    • Georgitis JW, Stone BD, Gottschlich G. Nasal inflammatory mediator release in ragweed allergic rhinitis - correlation with cellular influx into nasal secretions. Int Arch Allergy Appl Immunol 1991; 96: 231-237.
    • (1991) Int Arch Allergy Appl Immunol , vol.96 , pp. 231-237
    • Georgitis, J.W.1    Stone, B.D.2    Gottschlich, G.3
  • 61
    • 24544453952 scopus 로고
    • Mediator and cellular events in naturally ocurring seasonal allergic rhinitis
    • Wilson SJ, Lau LCK, Howarth PH. Mediator and cellular events in naturally ocurring seasonal allergic rhinitis. Clin Exp Allergy 1994; 24: 997A.
    • (1994) Clin Exp Allergy , vol.24
    • Wilson, S.J.1    Lau, L.C.K.2    Howarth, P.H.3
  • 62
    • 0025079644 scopus 로고
    • Nasal physiology and inflammatory mediators during natural pollen exposure
    • Skoner DP, Lee L Doyle WJ. Nasal physiology and inflammatory mediators during natural pollen exposure. Ann Allergy 1990; 65: 206-210.
    • (1990) Ann Allergy , vol.65 , pp. 206-210
    • Skoner, D.P.1    Lee, L.2    Doyle, W.J.3
  • 63
    • 85030336152 scopus 로고
    • 4) release in respiratory mucosa during natural exposure to ragweed in ragweed sensitive children
    • 4) release in respiratory mucosa during natural exposure to ragweed in ragweed sensitive children. Ped Research 1987; 21: A506-A506.
    • (1987) Ped Research , vol.21
    • Volovitz, B.1    Osur, S.L.2    Ogra, P.L.3
  • 64
    • 0027087201 scopus 로고
    • Indirect evidence of nasal inflammation assessed by titration of inflammatory mediators and enumeration of cells in nasal secretions of patients with chronic rhinitis
    • Knani J, Campbell A, Enander I. Indirect evidence of nasal inflammation assessed by titration of inflammatory mediators and enumeration of cells in nasal secretions of patients with chronic rhinitis. J Allergy Clin Immunol 1992; 90: 880.
    • (1992) J Allergy Clin Immunol , vol.90 , pp. 880
    • Knani, J.1    Campbell, A.2    Enander, I.3
  • 65
    • 0026847350 scopus 로고
    • Immunohistology of the nasal mucosa in seasonal allergic rhinitis - Increases in activated eosinophils and epithelial mast-cells
    • Bentley AM, Jacobson MR, Cumberworth V et al. Immunohistology of the nasal mucosa in seasonal allergic rhinitis - increases in activated eosinophils and epithelial mast-cells. J Allergy Clin Immunol 1992; 89: 877-883.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 877-883
    • Bentley, A.M.1    Jacobson, M.R.2    Cumberworth, V.3
  • 66
    • 0026603643 scopus 로고
    • Cytokine mRNA expression of IL-2, IL-4, IL-5 and GM-CSF in the nasal mucosa after local allergen provocation: Relationship to tissue eosinophilia
    • Durham SR, Ying S, Varney VA. Cytokine mRNA expression of IL-2, IL-4, IL-5 and GM-CSF in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia. J Immunol 1992; 148: 2390-2394.
    • (1992) J Immunol , vol.148 , pp. 2390-2394
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3
  • 68
    • 85004775161 scopus 로고
    • Effect of leukotriene D4 on nasal mucosal blood-flow, nasal airway-resistance and nasal secretions in humans
    • Bisgaard H, Olsson, Bende M. Effect of leukotriene D4 on nasal mucosal blood-flow, nasal airway-resistance and nasal secretions in humans. Clin Allergy 1986; 16: 289-297.
    • (1986) Clin Allergy , vol.16 , pp. 289-297
    • Bisgaard, H.1    Olsson2    Bende, M.3
  • 69
    • 0023820853 scopus 로고
    • The role of leukotriene-D4 in allergic rhinitis
    • Okuda M, Watase T, Mezawa A, Liu CM. The role of leukotriene-D4 in allergic rhinitis. Ann Allergy 1988; 60: 537-540.
    • (1988) Ann Allergy , vol.60 , pp. 537-540
    • Okuda, M.1    Watase, T.2    Mezawa, A.3    Liu, C.M.4
  • 70
    • 0027369276 scopus 로고
    • The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma
    • Israel E, Rubin P, Kemp JP et al. The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Medic 1993; 119: 1059-1066.
    • (1993) Ann Intern Medic , vol.119 , pp. 1059-1066
    • Israel, E.1    Rubin, P.2    Kemp, J.P.3
  • 71
    • 0028103864 scopus 로고
    • Effects of 6 weeks therapy with oral doses of ICI 204 219, a leukotriene D4 receptor antagonist in subjects with bronchial asthma
    • Spector SL, Smith LJ, Glass M and Accolate Asthma Trialists Group. Effects of 6 weeks therapy with oral doses of ICI 204 219, a leukotriene D4 receptor antagonist in subjects with bronchial asthma. Am J Respir Crit Care Med 1994; 150: 618-623.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 618-623
    • Spector, S.L.1    Smith, L.J.2    Glass, M.3
  • 72
    • 0042670934 scopus 로고
    • Selective inhibitor of slow reacting substance of anaphylaxis
    • Augstein J, Farmer JB, Lee TB. Selective inhibitor of slow reacting substance of anaphylaxis. Nature 1973; 254: 215-217.
    • (1973) Nature , vol.254 , pp. 215-217
    • Augstein, J.1    Farmer, J.B.2    Lee, T.B.3
  • 73
    • 0019453692 scopus 로고
    • Slow reacting substance if anaphylaxis antagonist FPL 55712 in chronic asthma
    • Lee TH, Walport MJ, Wilkinson AH, Turner-Warwick M, Kay AB. Slow reacting substance if anaphylaxis antagonist FPL 55712 in chronic asthma. Lancet 1981; ii: 304-305.
    • (1981) Lancet , vol.2 , pp. 304-305
    • Lee, T.H.1    Walport, M.J.2    Wilkinson, A.H.3    Turner-Warwick, M.4    Kay, A.B.5
  • 74
    • 0022545227 scopus 로고
    • L-649 923, sodium (beta S*, gamma R*)-4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-propylthio)-gamma-hydroxy- beta-methylbenzenebutanoate, a selective, orally active leukotriene receptor antagonist
    • Jones TR, Young R, Champion E et al. L-649 923, sodium (beta S*, gamma R*)-4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-propylthio)-gamma-hydroxy- beta-methylbenzenebutanoate, a selective, orally active leukotriene receptor antagonist. Can J Physiol Pharmacol 1986; 64: 1068-1075.
    • (1986) Can J Physiol Pharmacol , vol.64 , pp. 1068-1075
    • Jones, T.R.1    Young, R.2    Champion, E.3
  • 75
    • 0023238611 scopus 로고
    • The effect of an oral leukotriene antagonist L-649 923 on histamine and leukotriene D4-induced bronchoconstriction in normal man
    • Barnes N, Piper PJ, Costello J. The effect of an oral leukotriene antagonist L-649 923 on histamine and leukotriene D4-induced bronchoconstriction in normal man. J Allergy Clin Immunol 1987; 79: 816-821.
    • (1987) J Allergy Clin Immunol , vol.79 , pp. 816-821
    • Barnes, N.1    Piper, P.J.2    Costello, J.3
  • 76
    • 0023789233 scopus 로고
    • Dose-related antagonism of leukotriene-D4-induced bronchoconstriction by po administration of Ly-171883 in nonasthmatic subjects
    • Phillips GD, Rafferty P, Robinson C, Holgate ST, Dose-related antagonism of leukotriene-D4-induced bronchoconstriction by po administration of Ly-171883 in nonasthmatic subjects. J Pharmacol Exp Therap 1988; 246: 732-738.
    • (1988) J Pharmacol Exp Therap , vol.246 , pp. 732-738
    • Phillips, G.D.1    Rafferty, P.2    Robinson, C.3    Holgate, S.T.4
  • 77
    • 0026000552 scopus 로고
    • The effect of inhaled Ly-170680 on leukotriene-D4-induced bronchoconstriction in healthy volunteers
    • Wood-Baker R, Phillips GD, Lucas RA, Turner GA, Holgate ST. The effect of inhaled Ly-170680 on leukotriene-D4-induced bronchoconstriction in healthy volunteers. Drug Invest 1991; 3: 239-247.
    • (1991) Drug Invest , vol.3 , pp. 239-247
    • Wood-Baker, R.1    Phillips, G.D.2    Lucas, R.A.3    Turner, G.A.4    Holgate, S.T.5
  • 78
    • 0026092704 scopus 로고
    • The effect of aerosolized SK&F 104353-Z2 on the bronchoconstrictor effect of leukotriene D4 in asthmatics
    • Joos GF, Kips JC, Pauwels RA, Van Der Straeten ME. The effect of aerosolized SK&F 104353-Z2 on the bronchoconstrictor effect of leukotriene D4 in asthmatics. Pulmon Pharmacol 1991; 4: 37-42.
    • (1991) Pulmon Pharmacol , vol.4 , pp. 37-42
    • Joos, G.F.1    Kips, J.C.2    Pauwels, R.A.3    Van Der Straeten, M.E.4
  • 79
    • 0025255862 scopus 로고
    • The preclinical pharmacology of ICI 204 219. A peptide leukotriene antagonist
    • Krell RD, Aharony D, Buckner CK et al. The preclinical pharmacology of ICI 204 219. A peptide leukotriene antagonist. Am Rev Respir Dis 1990; 141: 978-987.
    • (1990) Am Rev Respir Dis , vol.141 , pp. 978-987
    • Krell, R.D.1    Aharony, D.2    Buckner, C.K.3
  • 80
    • 0025945496 scopus 로고
    • MK-571, a potent antagonist of leukotriene D4-induced bronchoconstriction in the human
    • Kips JC, Joos GF, DeLepeleire I et al. MK-571, a potent antagonist of leukotriene D4-induced bronchoconstriction in the human. Am Rev Respir Dis 1991; 144: 617-621.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 617-621
    • Kips, J.C.1    Joos, G.F.2    DeLepeleire, I.3
  • 81
    • 0031015528 scopus 로고    scopus 로고
    • Montelukast causes prolonged, potent leukotriene D-4-receptor antagonism in the airways of patients with asthma
    • DeLepeleire I, Reiss TF, Rochette F et al. Montelukast causes prolonged, potent leukotriene D-4-receptor antagonism in the airways of patients with asthma. Clin Pharmacol Therap 1997; 61: 83-92.
    • (1997) Clin Pharmacol Therap , vol.61 , pp. 83-92
    • DeLepeleire, I.1    Reiss, T.F.2    Rochette, F.3
  • 82
    • 0024391809 scopus 로고
    • Effect of the oral leukotriene D4 antagonist LY171883 on inhaled and intradermal challenge with antigen and leukotriene D4 in atopic subjects
    • Fuller RW, Black PN, Dollery CT. Effect of the oral leukotriene D4 antagonist LY171883 on inhaled and intradermal challenge with antigen and leukotriene D4 in atopic subjects. J Allergy Clin mmunol 1989; 83: 939-944.
    • (1989) J Allergy Clin Mmunol , vol.83 , pp. 939-944
    • Fuller, R.W.1    Black, P.N.2    Dollery, C.T.3
  • 83
    • 0023223913 scopus 로고
    • The effect of an oral leukotriene D4 antagonist L-649 923 on the response to inhaled antigen in asthma
    • Britton JR, Hanley SP, Tattersfield AE. The effect of an oral leukotriene D4 antagonist L-649 923 on the response to inhaled antigen in asthma. J Allergy Clin Immunol 1987; 79: 811-816.
    • (1987) J Allergy Clin Immunol , vol.79 , pp. 811-816
    • Britton, J.R.1    Hanley, S.P.2    Tattersfield, A.E.3
  • 84
    • 0026066945 scopus 로고
    • Effect of cysteinyl-leukotriene receptor antagonist ICI 204 219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects
    • Taylor IK, O'Shaughnessy KM, Fuller RW, Dollery CT. Effect of cysteinyl-leukotriene receptor antagonist ICI 204 219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects. Lancet 1991; 337: 690-694.
    • (1991) Lancet , vol.337 , pp. 690-694
    • Taylor, I.K.1    O'Shaughnessy, K.M.2    Fuller, R.W.3    Dollery, C.T.4
  • 85
    • 0027299275 scopus 로고
    • Potent leukotriene D4 receptor antagonist ICI 204 219 given by the inhaled route inhibits the early but not the late phase of allergen-induced bronchoconstriction
    • O'Shaughnessy KM, Taylor IK, O'Connor B, O'Connell F, Thomson H. Potent leukotriene D4 receptor antagonist ICI 204 219 given by the inhaled route inhibits the early but not the late phase of allergen-induced bronchoconstriction. Am Rev Respir Dis 1993; 147: 1431-1435.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 1431-1435
    • O'Shaughnessy, K.M.1    Taylor, I.K.2    O'Connor, B.3    O'Connell, F.4    Thomson, H.5
  • 86
    • 0026524337 scopus 로고
    • Effect of the oral leukotriene antagonist, ICI 204 219, on antigen-induced bronchoconstriction in subjects with asthma
    • Findlay SR, Barden JM, Easley CB, Glass M. Effect of the oral leukotriene antagonist, ICI 204 219, on antigen-induced bronchoconstriction in subjects with asthma. J Allergy Clin Immunol 1992; 89: 1040-1045.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 1040-1045
    • Findlay, S.R.1    Barden, J.M.2    Easley, C.B.3    Glass, M.4
  • 87
    • 0028327560 scopus 로고
    • The leukotriene-antagonist ICI-204219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics
    • Dahlen B, Zetterstrom O, Bjorck T, Dahlen SE. The leukotriene-antagonist ICI-204219 inhibits the early airway reaction to cumulative bronchial challenge with allergen in atopic asthmatics. Eur Resp J 1994; 7: 324-331.
    • (1994) Eur Resp J , vol.7 , pp. 324-331
    • Dahlen, B.1    Zetterstrom, O.2    Bjorck, T.3    Dahlen, S.E.4
  • 88
    • 0026610937 scopus 로고
    • Leukotriene-D(4) receptor blockade inhibits the immediate and late bronchoconstrictor responses to inhaled antigen in patients with asthma
    • Rasmussen JB, Eriksson LO, Margolskee DJ, Tagari P, Williams VC, Andersson KE. Leukotriene-D(4) receptor blockade inhibits the immediate and late bronchoconstrictor responses to inhaled antigen in patients with asthma. J Allergy Clin Immunol 1992; 90: 193-201.
    • (1992) J Allergy Clin Immunol , vol.90 , pp. 193-201
    • Rasmussen, J.B.1    Eriksson, L.O.2    Margolskee, D.J.3    Tagari, P.4    Williams, V.C.5    Andersson, K.E.6
  • 89
    • 0025951165 scopus 로고
    • The potent and selective sulfidopeptide leukotriene antagonist, SK-and-F-104 353, inhibits aspirin-induced asthma
    • Christie PE, Smith CM, Lee TH. The potent and selective sulfidopeptide leukotriene antagonist, SK-and-F-104 353, inhibits aspirin-induced asthma. Am Rev Respir Dis 1991; 144: 957-958.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 957-958
    • Christie, P.E.1    Smith, C.M.2    Lee, T.H.3
  • 90
    • 13144277029 scopus 로고
    • The leukotriene antagonist MK-0679 improves baseline pulmonary function and blocks aspirin-induced airways obstruction in aspirin-sensitive asthmatics
    • Kumlin M, Johansson H, Larsson C et al. The leukotriene antagonist MK-0679 improves baseline pulmonary function and blocks aspirin-induced airways obstruction in aspirin-sensitive asthmatics. Am Rev Respir Dis 1992; 145: A15.
    • (1992) Am Rev Respir Dis , vol.145
    • Kumlin, M.1    Johansson, H.2    Larsson, C.3
  • 91
    • 0024434799 scopus 로고
    • Effect of a leukotriene antagonist, LY171883, on cold air-induced bronchoconstriction in asthmatics
    • Israel E, Juniper EF, Callaghan JT et al. Effect of a leukotriene antagonist, LY171883, on cold air-induced bronchoconstriction in asthmatics. Am Rev Respir Dis 1989; 140: 1348-1353.
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1348-1353
    • Israel, E.1    Juniper, E.F.2    Callaghan, J.T.3
  • 92
    • 0026872032 scopus 로고
    • Prevention of exercise-induced bronchoconstriction by a new leukotriene antagonist (SK&F-104353) - A double-blind-study versus disodium-cromoglycate and placebo
    • Robuschi M, Riva E, Fuccella LM et al. Prevention of exercise-induced bronchoconstriction by a new leukotriene antagonist (SK&F-104353) - a double-blind-study versus disodium-cromoglycate and placebo. Am Rev Respir Dis 1992; 145: 1285-1288.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 1285-1288
    • Robuschi, M.1    Riva, E.2    Fuccella, L.M.3
  • 93
    • 0027213164 scopus 로고
    • The protective effect of inhaled leukotriene-D(4) receptor antagonist ICI-204 219 against exercise-induced asthma
    • Makker HK, Lau LC, Thomson HW, Binks SM, Holgate ST. The protective effect of inhaled leukotriene-D(4) receptor antagonist ICI-204 219 against exercise-induced asthma. Am Rev Respir Dis 1993; 147: 1413-1418.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 1413-1418
    • Makker, H.K.1    Lau, L.C.2    Thomson, H.W.3    Binks, S.M.4    Holgate, S.T.5
  • 95
    • 0031430503 scopus 로고    scopus 로고
    • Dose-related protection of exercise bronchoconstriction by montelukast, a cysteinyl leukotriene-receptor antagonist, at the end of a once-daily dosing interval
    • Bronsky EA, Kemp JP, Zhang J, Guerreiro D, Reiss TF. Dose-related protection of exercise bronchoconstriction by montelukast, a cysteinyl leukotriene-receptor antagonist, at the end of a once-daily dosing interval. Clin Pharmacol Therap 1997; 62: 556-561.
    • (1997) Clin Pharmacol Therap , vol.62 , pp. 556-561
    • Bronsky, E.A.1    Kemp, J.P.2    Zhang, J.3    Guerreiro, D.4    Reiss, T.F.5
  • 96
    • 0001622954 scopus 로고    scopus 로고
    • Montelukast, a leukotriene receptor antagonist, inhibits exercise-induced bronchoconstriction in 6- to 14-year-old children
    • Kemp JP, Dockhorn RJ, Shapiro GG et al. Montelukast, a leukotriene receptor antagonist, inhibits exercise-induced bronchoconstriction in 6- to 14-year-old children. J Allergy Clin Immunol 1997; 99: 1314-1314.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 1314-1314
    • Kemp, J.P.1    Dockhorn, R.J.2    Shapiro, G.G.3
  • 97
    • 0030696614 scopus 로고    scopus 로고
    • 4 after exercise and attenuation of exercise-induced bronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist
    • 4 after exercise and attenuation of exercise-induced bronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist. Thorax 1997; 52: 1030-1035.
    • (1997) Thorax , vol.52 , pp. 1030-1035
    • Reiss, T.F.1    Hill, J.B.2    Harman, B.3
  • 99
    • 0028014328 scopus 로고
    • Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi
    • Ellis JL, Undem BJ. Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi. Am J Respir Crit Care Med 1994; 149: 118-122.
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 118-122
    • Ellis, J.L.1    Undem, B.J.2
  • 100
    • 0027253792 scopus 로고
    • Acute bronchodilation with an intravenously administered leukotriene- D(4) antagonist, MK-679
    • Impens N, Reiss TF, Teahan JA et al. Acute bronchodilation with an intravenously administered leukotriene- D(4) antagonist, MK-679. Am Rev Respir Dis 1993; 147: 1442-1446.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 1442-1446
    • Impens, N.1    Reiss, T.F.2    Teahan, J.A.3
  • 101
    • 0025802839 scopus 로고
    • Lung-function improvement in asthma with a cysteinyl-leukotriene receptor antagonist
    • Hui KP, Barnes NC. Lung-function improvement in asthma with a cysteinyl-leukotriene receptor antagonist. Lancet 1991; 337: 1062-1063.
    • (1991) Lancet , vol.337 , pp. 1062-1063
    • Hui, K.P.1    Barnes, N.C.2
  • 103
    • 0027725249 scopus 로고
    • Effect of the leukotriene receptor antagonist MK-0679 on base-line pulmonary-function in aspirin-sensitive asthmatic subjects
    • Dahlen B, Margolskee DJ, Zetterstrom O, Dahlen SE. Effect of the leukotriene receptor antagonist MK-0679 on base-line pulmonary-function in aspirin-sensitive asthmatic subjects. Thorax 1993; 48: 1205-1210.
    • (1993) Thorax , vol.48 , pp. 1205-1210
    • Dahlen, B.1    Margolskee, D.J.2    Zetterstrom, O.3    Dahlen, S.E.4
  • 104
    • 0009569215 scopus 로고    scopus 로고
    • Intravenous pranlukast (Ultair®) inhibits LTD(4)-induced bronchoconstriction in patients with asthma
    • Smith LJ, Jorkasky DK, Carr S, Boike SC. Intravenous pranlukast (Ultair®) inhibits LTD(4)-induced bronchoconstriction in patients with asthma. J Allergy Clin Immunol 1997; 99: 1341-1341.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 1341-1341
    • Smith, L.J.1    Jorkasky, D.K.2    Carr, S.3    Boike, S.C.4
  • 105
    • 0024474179 scopus 로고
    • 4-receptor antagonist improves pulmonary function in patients with mild, chronic asthma
    • 4-receptor antagonist improves pulmonary function in patients with mild, chronic asthma. Am Rev Respir Dis 1989; 140: 1336-1339.
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1336-1339
    • Cloud, M.L.1    Enas, G.G.2    Kemp, J.3
  • 106
    • 0029970797 scopus 로고    scopus 로고
    • Effects of montelukast (MK-0476), a new potent cysteinyl leukotriene (LTD(4)) receptor antagonist, in patients with chronic asthma
    • Reiss TF, Altman LC, Chervinsky P et al. Effects of montelukast (MK-0476), a new potent cysteinyl leukotriene (LTD(4)) receptor antagonist, in patients with chronic asthma. J Allergy Clin Immunol 1996; 98: 528-534.
    • (1996) J Allergy Clin Immunol , vol.98 , pp. 528-534
    • Reiss, T.F.1    Altman, L.C.2    Chervinsky, P.3
  • 107
    • 0027469691 scopus 로고
    • Effect of a leukotriene antagonist, ONO-1078, on bronchial hyperresponsiveness in patients with asthma
    • Fujimura M, Sakamo S, Kamio Y, Matsuda T. Effect of a leukotriene antagonist, ONO-1078, on bronchial hyperresponsiveness in patients with asthma. Respir Med 1993; 87: 133-138.
    • (1993) Respir Med , vol.87 , pp. 133-138
    • Fujimura, M.1    Sakamo, S.2    Kamio, Y.3    Matsuda, T.4
  • 108
    • 0030875339 scopus 로고    scopus 로고
    • Zafirlukast for symptomatic mild-to-moderate asthma: A 13-week multicenter study
    • Fish JE, Kemp JP, Lockey RF et al. Zafirlukast for symptomatic mild-to-moderate asthma: A 13-week multicenter study. Clin Therap 1997; 19: 675-690.
    • (1997) Clin Therap , vol.19 , pp. 675-690
    • Fish, J.E.1    Kemp, J.P.2    Lockey, R.F.3
  • 109
    • 0031057451 scopus 로고    scopus 로고
    • Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma - A randomized, double-blind, placebo-controlled trial
    • Suissa S, Dennis R, Ernst P, Sheehy O, Wood-Dauphinee S. Effectiveness of the leukotriene receptor antagonist zafirlukast for mild-to-moderate asthma - a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1997; 126: 177.
    • (1997) Ann Intern Med , vol.126 , pp. 177
    • Suissa, S.1    Dennis, R.2    Ernst, P.3    Sheehy, O.4    Wood-Dauphinee, S.5
  • 110
    • 6844250776 scopus 로고    scopus 로고
    • Pulmonary infiltrates, eosinophilia and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving receiving zafirlukast
    • Wechsler ME, Garpestad E, Flier SR et al. Pulmonary infiltrates, eosinophilia and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving receiving zafirlukast. J Am Med Assoc 1998; 279: 455-457.
    • (1998) J Am Med Assoc , vol.279 , pp. 455-457
    • Wechsler, M.E.1    Garpestad, E.2    Flier, S.R.3
  • 111
    • 0003758314 scopus 로고
    • Effect of multiple doses of RG 12525, an oral leukotriene D4 antagonist, in chronic asthma
    • Wahedna I, Wisniewski AFZ, Wong CS, Tattersfield AE. Effect of multiple doses of RG 12525, an oral leukotriene D4 antagonist, in chronic asthma. Am Rev Respir Dis 1992; 145: A16.
    • (1992) Am Rev Respir Dis , vol.145
    • Wahedna, I.1    Wisniewski, A.F.Z.2    Wong, C.S.3    Tattersfield, A.E.4
  • 112
    • 0030903255 scopus 로고    scopus 로고
    • Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid
    • Tamaoki J, Kondo M, Sakai N et al. Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid. Am J Respir Crit Care Med 1997; 155: 1235-1240.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1235-1240
    • Tamaoki, J.1    Kondo, M.2    Sakai, N.3
  • 113
    • 0030807577 scopus 로고    scopus 로고
    • Therapeutic effect of pranlukast, a selective cysteinyl leukotriene receptor antagonist, on bronchial asthma
    • Oosaki R, Mizushima Y, Kashii T, Kawasaki A, Kobayashi M. Therapeutic effect of pranlukast, a selective cysteinyl leukotriene receptor antagonist, on bronchial asthma. Int Arch Allergy Immunol 1997; 114: 97-100.
    • (1997) Int Arch Allergy Immunol , vol.114 , pp. 97-100
    • Oosaki, R.1    Mizushima, Y.2    Kashii, T.3    Kawasaki, A.4    Kobayashi, M.5
  • 114
    • 0030872408 scopus 로고    scopus 로고
    • Pranlukast, a novel leukotriene receptor antagonist: Results of the first European, placebo controlled, multicentre clinical study in asthma
    • Barnes NC, Pujet JC. Pranlukast, a novel leukotriene receptor antagonist: Results of the first European, placebo controlled, multicentre clinical study in asthma. Thorax 1997; 52: 523-527.
    • (1997) Thorax , vol.52 , pp. 523-527
    • Barnes, N.C.1    Pujet, J.C.2
  • 115
    • 0030798841 scopus 로고    scopus 로고
    • Results of the first US double-blind, placebo-controlled, multi-center clinical study in asthma with pranlukast, a novel leukotriene receptor antagonist
    • Grossman J, Faiferman I, Dubb JW et al. Results of the first US double-blind, placebo-controlled, multi-center clinical study in asthma with pranlukast, a novel leukotriene receptor antagonist. J Asthma 1997; 34: 321-328.
    • (1997) J Asthma , vol.34 , pp. 321-328
    • Grossman, J.1    Faiferman, I.2    Dubb, J.W.3
  • 117
    • 0028990176 scopus 로고
    • The leukotriene D4 receptor antagonist, ICI 2 204,219, relieves symptoms of acute seasonals rhinitis
    • Donnelly AL, Glass M, Minkwitz MC, Casale TB. The leukotriene D4 receptor antagonist, ICI 2 204,219, relieves symptoms of acute seasonals rhinitis. Am J Respir Crit Care Med 1995; 151: 1734-1739.
    • (1995) Am J Respir Crit Care Med , vol.151 , pp. 1734-1739
    • Donnelly, A.L.1    Glass, M.2    Minkwitz, M.C.3    Casale, T.B.4
  • 118
    • 0000436661 scopus 로고    scopus 로고
    • Pranlukast (Ultair™, SB 205312, ONO-1078), an oral leukotriene receptor antagonist, relieves symptoms in patients with seasonal allergic rhinitis (SAR)
    • Grossman J, Ratner PH, Nathan R, Adelglass J, deJong B. Pranlukast (Ultair™, SB 205312, ONO-1078), an oral leukotriene receptor antagonist, relieves symptoms in patients with seasonal allergic rhinitis (SAR). J Allergy Clin Immunol 1997; 99: 1799.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 1799
    • Grossman, J.1    Ratner, P.H.2    Nathan, R.3    Adelglass, J.4    DeJong, B.5
  • 119
    • 0025823424 scopus 로고
    • 5-lipoxygenase-activating protein is the target of a quinolone class of leukotriene biosynthesis inhibitors
    • Evans JF, Leville C, Mancini JA et al. 5-lipoxygenase-activating protein is the target of a quinolone class of leukotriene biosynthesis inhibitors. Mole Pharmacol 1991; 40: 22-27.
    • (1991) Mole Pharmacol , vol.40 , pp. 22-27
    • Evans, J.F.1    Leville, C.2    Mancini, J.A.3
  • 120
    • 0025808251 scopus 로고
    • Hydroxamic acids and hydroxureas as inhibitors of arachidonate 5-lipoxygenase
    • Garland LG, Salmon JA. Hydroxamic acids and hydroxureas as inhibitors of arachidonate 5-lipoxygenase. Drugs Future 1991; 16: 547-558.
    • (1991) Drugs Future , vol.16 , pp. 547-558
    • Garland, L.G.1    Salmon, J.A.2
  • 121
    • 0026078163 scopus 로고
    • Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients
    • Hui KP, Taylor IK, Taylor GW et al. Effect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patients. Thorax 1991; 46: 184-189.
    • (1991) Thorax , vol.46 , pp. 184-189
    • Hui, K.P.1    Taylor, I.K.2    Taylor, G.W.3
  • 122
    • 0027458882 scopus 로고
    • Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses
    • Friedman BS, Bel EH, Buntinx A et al. Oral leukotriene inhibitor (MK-886) blocks allergen-induced airway responses. Am Rev Respir Dis 1993; 147: 839-844.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 839-844
    • Friedman, B.S.1    Bel, E.H.2    Buntinx, A.3
  • 123
    • 0028821025 scopus 로고
    • The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in-vivo
    • Diamant Z, Timmers MC, Vanderveen H et al. The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in-vivo. J Allergy Clin Immunol 1995; 95: 42-51.
    • (1995) J Allergy Clin Immunol , vol.95 , pp. 42-51
    • Diamant, Z.1    Timmers, M.C.2    Vanderveen, H.3
  • 124
    • 0027762572 scopus 로고
    • The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin
    • Israel E, Fischer AR, Rosenberg MA et al. The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. Am Rev Respir Dis 1993; 148: 1447-1451.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 1447-1451
    • Israel, E.1    Fischer, A.R.2    Rosenberg, M.A.3
  • 125
    • 0028114047 scopus 로고
    • Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma
    • Nasser SMS, Bell GS, Foster S et al. Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma. Thorax 1994; 49: 749-756.
    • (1994) Thorax , vol.49 , pp. 749-756
    • Nasser, S.M.S.1    Bell, G.S.2    Foster, S.3
  • 127
    • 0029937854 scopus 로고    scopus 로고
    • Inhibition of exercise-induced bronchospasm by zileuton - A 5-lipoxygenase inhibitor
    • Meltzer SS, Hasday JD, Cohn J, Bleecker ER. Inhibition of exercise-induced bronchospasm by zileuton - a 5-lipoxygenase inhibitor. Am J Respir Crit Care Med 1996; 153: 931-935.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 931-935
    • Meltzer, S.S.1    Hasday, J.D.2    Cohn, J.3    Bleecker, E.R.4
  • 128
    • 0000969643 scopus 로고
    • The efficacy of an oral inhibitor of leukotriene synthesis (MK-0591) in asthmatics treated with inhaled steroids
    • Chapman KR, Friedman BS, Shingo S, Heyse J, Reiss T, Spector R. The efficacy of an oral inhibitor of leukotriene synthesis (MK-0591) in asthmatics treated with inhaled steroids. Am J Respir Crit Care Med 1994; 149: A215.
    • (1994) Am J Respir Crit Care Med , vol.149
    • Chapman, K.R.1    Friedman, B.S.2    Shingo, S.3    Heyse, J.4    Reiss, T.5    Spector, R.6
  • 129
    • 0029853741 scopus 로고    scopus 로고
    • Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma - A 6-month randomized multicenter trial
    • Liu MC, Dube LM, Lancaster J. Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma - a 6-month randomized multicenter trial. J Allergy Clin Immunol 1996; 98: 859-871.
    • (1996) J Allergy Clin Immunol , vol.98 , pp. 859-871
    • Liu, M.C.1    Dube, L.M.2    Lancaster, J.3
  • 130
    • 0025685169 scopus 로고
    • Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-LO inhibitor
    • Knapp HR. Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-LO inhibitor. N Engl J Med 1990; 323: 1740-1748.
    • (1990) N Engl J Med , vol.323 , pp. 1740-1748
    • Knapp, H.R.1
  • 131
    • 0029915834 scopus 로고    scopus 로고
    • Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma - A randomized controlled trial
    • Israel E, Cohn J, Dube L, Drazen JM. Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma - a randomized controlled trial. J Am Med Assoc 1996; 275: 931-936.
    • (1996) J Am Med Assoc , vol.275 , pp. 931-936
    • Israel, E.1    Cohn, J.2    Dube, L.3    Drazen, J.M.4
  • 132
    • 0031110457 scopus 로고    scopus 로고
    • Randomized trial of zileuton in patients with moderate asthma: Effect of reduced dosing frequency and amounts on pulmonary function and asthma symptoms
    • DuBuske LM, Grossman J, Dube LM et al. Randomized trial of zileuton in patients with moderate asthma: effect of reduced dosing frequency and amounts on pulmonary function and asthma symptoms. Am J Managed Care 1997; 3: 633-640.
    • (1997) Am J Managed Care , vol.3 , pp. 633-640
    • DuBuske, L.M.1    Grossman, J.2    Dube, L.M.3
  • 133
    • 0031964913 scopus 로고    scopus 로고
    • A randomised controlled trial comparing zileuton with theophylline in moderate asthma
    • Schwartz HJ, Petty T, Dube LM, Swanson LJ, Lancaster JF. A randomised controlled trial comparing zileuton with theophylline in moderate asthma. Arch Intern Med 1998; 158: 141-148.
    • (1998) Arch Intern Med , vol.158 , pp. 141-148
    • Schwartz, H.J.1    Petty, T.2    Dube, L.M.3    Swanson, L.J.4    Lancaster, J.F.5
  • 134
    • 0029074331 scopus 로고
    • The influence of 5-lipoxygenase inhibition in allergic rhinitis
    • Howarth PH, Harrison K, Lau L. The influence of 5-lipoxygenase inhibition in allergic rhinitis. Int Arch Allergy Immunol 1995; 107: 423-424.
    • (1995) Int Arch Allergy Immunol , vol.107 , pp. 423-424
    • Howarth, P.H.1    Harrison, K.2    Lau, L.3
  • 135
    • 0025312294 scopus 로고
    • Randomized double-blind, placebo-controlled clinical trial of a selective 5-lipoxygenase inhibitor (AA-861) for the prevention of seasonal allergic rhinitis
    • Ancill RJ, Takahashi Y, Kibune Y, Campbell R, Smith JR. Randomized double-blind, placebo-controlled clinical trial of a selective 5-lipoxygenase inhibitor (AA-861) for the prevention of seasonal allergic rhinitis. J Int Med Res 1990; 18: 75-88.
    • (1990) J Int Med Res , vol.18 , pp. 75-88
    • Ancill, R.J.1    Takahashi, Y.2    Kibune, Y.3    Campbell, R.4    Smith, J.R.5
  • 137
    • 0028643629 scopus 로고
    • Direct evidence for a role of the mast-cell in the nasal response to aspirin in aspirin-sensitive asthma
    • Fischer AR, Rosenberg MA, Lilly CM et al. Direct evidence for a role of the mast-cell in the nasal response to aspirin in aspirin-sensitive asthma. J Allergy Clin Immunol 1994; 94: 1046-1056.
    • (1994) J Allergy Clin Immunol , vol.94 , pp. 1046-1056
    • Fischer, A.R.1    Rosenberg, M.A.2    Lilly, C.M.3
  • 138
    • 0031010471 scopus 로고    scopus 로고
    • Focus on zileuton: The first FDA-approved agent of a new class of drugs for the management of asthma
    • Owens CA, Grundy GW. Focus on zileuton: the first FDA-approved agent of a new class of drugs for the management of asthma. Formulary 1997; 32: 455.
    • (1997) Formulary , vol.32 , pp. 455
    • Owens, C.A.1    Grundy, G.W.2
  • 139
    • 0029955405 scopus 로고    scopus 로고
    • Management of asthma with zafirlukast-clinical experience and tolerability profile
    • Spector SL. Management of asthma with zafirlukast-clinical experience and tolerability profile. Drugs 1996; 52: 36-46.
    • (1996) Drugs , vol.52 , pp. 36-46
    • Spector, S.L.1
  • 140
    • 0031039964 scopus 로고    scopus 로고
    • Worldwide clinical experience with the first marketed leukotriene receptor antagonist
    • Barnes NC, deJong B, Miyamato T. Worldwide clinical experience with the first marketed leukotriene receptor antagonist. Chest 1997; 111: (Suppl.) S52-S60.
    • (1997) Chest , vol.111 , Issue.SUPPL.
    • Barnes, N.C.1    DeJong, B.2    Miyamato, T.3
  • 141
    • 0031025167 scopus 로고    scopus 로고
    • The use of 5-lipoxygenase inhibitors and leukotriene receptor antagonists in the treatment of chronic asthma
    • Sorkness CA. The use of 5-lipoxygenase inhibitors and leukotriene receptor antagonists in the treatment of chronic asthma. Pharmacotherapy 1997; 17 (Suppl.): S50-S54.
    • (1997) Pharmacotherapy , vol.17 , Issue.SUPPL.
    • Sorkness, C.A.1
  • 142
    • 0030866313 scopus 로고    scopus 로고
    • Zafirlukast: The first leukotriene-receptor antagonist approved for the treatment of asthma
    • Kelloway JS, Zafirlukast: the first leukotriene-receptor antagonist approved for the treatment of asthma. Ann Pharmacotherapy 1997; 31: 1012-1021.
    • (1997) Ann Pharmacotherapy , vol.31 , pp. 1012-1021
    • Kelloway, J.S.1
  • 144
    • 0019971503 scopus 로고
    • Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro
    • Marom Z, Shelhamer JH, Bach MK, Morton, DR, Kaliner, M. Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro. Am Rev Respir Dis 1982; 126: 449-451.
    • (1982) Am Rev Respir Dis , vol.126 , pp. 449-451
    • Marom, Z.1    Shelhamer, J.H.2    Bach, M.K.3    Morton, D.R.4    Kaliner, M.5
  • 145
    • 0021076990 scopus 로고
    • Response of human skin to intra-dermal injection of leukotrienes C4, D4 and B4
    • Camp RDR, Coutts AA, Greaves MW, Kay AB, Walport MK. Response of human skin to intra-dermal injection of leukotrienes C4, D4 and B4. B J Pharmacol 1983; 80: 497-502.
    • (1983) B J Pharmacol , vol.80 , pp. 497-502
    • Camp, R.D.R.1    Coutts, A.A.2    Greaves, M.W.3    Kay, A.B.4    Walport, M.K.5
  • 147
    • 0020001881 scopus 로고
    • Leukotriene D4: A potent coronary artery vasoconstrictor associated with impaired ventricular contraction
    • Michelassi F, Landa L, Hill RD, Lowenstein E, Watkins WD, Petkau AJ. Leukotriene D4: a potent coronary artery vasoconstrictor associated with impaired ventricular contraction. Science 1982; 217: 841-843.
    • (1982) Science , vol.217 , pp. 841-843
    • Michelassi, F.1    Landa, L.2    Hill, R.D.3    Lowenstein, E.4    Watkins, W.D.5    Petkau, A.J.6
  • 149
    • 0021234498 scopus 로고
    • Renal and systemic hemodynamic responses to intravenous infusion of leukotriene C4 in the rate
    • Badr KF, Baylis C, Pfeffer JM et al. Renal and systemic hemodynamic responses to intravenous infusion of leukotriene C4 in the rate. Circ. Res 1984; 54: 492-499.
    • (1984) Circ. Res , vol.54 , pp. 492-499
    • Badr, K.F.1    Baylis, C.2    Pfeffer, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.