Worldwide clinical experience with the first marketed leukotriene receptor antagonist

Chest

Volumn 111, Issue 2 SUPPL., 1997, Pages 52S-60S

  Barnes, Neil C ^a   De Jong, Bert ^b   Miyamoto, Terumasa ^c  

^a LONDON CHEST HOSPITAL   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

airway disease; allergic rhinitis; asthma; leukotriene receptor antagonist; ONO 1078; pranlukast; SB 205312

Indexed keywords

ACETYLSALICYLIC ACID; AZELASTINE; BECLOMETASONE DIPROPIONATE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; HISTAMINE; LEUKOTRIENE D4; LEUKOTRIENE RECEPTOR BLOCKING AGENT; PLACEBO; PRANLUKAST; PREDNISOLONE; SALBUTAMOL; XANTHINE DERIVATIVE;

ALLERGIC RHINITIS; ARTICLE; ASTHMA; CLINICAL TRIAL; DAILY LIFE ACTIVITY; DRUG EFFICACY; DRUG MARKETING; DRUG SAFETY; DRUG TOLERABILITY; EUROPE; FORCED EXPIRATORY VOLUME; GASTROINTESTINAL SYMPTOM; HUMAN; INHALATIONAL DRUG ADMINISTRATION; JAPAN; NORTH AMERICA; ORAL DRUG ADMINISTRATION; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL;

EID: 0031039964     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.111.2_Supplement.52S     Document Type: Article

References (20)

1. Creticos PS, Peters SP, Adkinson NF Jr, et al. Peptide leukotriene release after antigen challenge in patients sensitive to ragweed. N Engl J Med 1984; 310:1626-30
2. Ferreri NR, Rowland WC, Stevenson DD, et al. Release of leukotrienes, prostaglandins, and histamine into nasal secretions of aspirin-sensitive asthmatics during reaction to aspirin. Am Rev Respir Dis 1988; 137:847-54
3. Henderson WR Jr. Role of leukotrienes in asthma. Ann Allergy 1994; 72:272-78
4. Knapp HR, Murray JJ. Leukotrienes as mediators of nasal inflammation. Adv Prostaglandin Thromboxane Leukot Res 1994; 22:279-88
5. 4 from granulocytes of normal controls, allergic rhinitis, and asthmatic subjects. Ann Allergy 1990; 65:228-32
6. Naclerio RM, Baroody FM, Togias AG. The role of leukotrienes in allergic rhinitis: a review. Am Rev Respir Dis 1991; 143:591-5
7. 4 in allergic rhinitis. Ann Allergy 1988; 60:537-40
8. Wang D, Clement P, Smitz J, et al. Concentrations of chemical mediators in nasal secretions after nasal allergen challenges in atopic patients. Eur Arch Otorhinolaryngol 1995; 252(suppl 1):S40-3
9. Israel E, Rubin P, Kemp JP, et al. The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med 1993; 119:1059-66
10. 4-receptor antagonist improves pulmonary function in patients with mild, chronic asthma. Am Rev Respir Dis 1989; 140: 1336-39
11. 4 receptor antagonist, in subjects with bronchial asthma. Am J Respir Grit Care Med 1994; 150:618-23
12. Barnes NC, Pujet J-C. Pranlukast, a novel leukotriene receptor antagonist: results of the first European, placebo-controlled, multicentre clinical study in asthma. Thorax (in press)
13. Grossman J, Faiferman I, Dubb JW, et al. Results of the first double-blind, placebo-controlled, multicenter clinical study in asthma with pranlukast, a novel leukotriene receptor antagonist. J Asthma (in press)
14. Yamamoto H, Nagata M, Kuramitsu K, et al. Inhibition of analgesic-induced asthma by leukotriene receptor antagonist ONO-1078. Am J Respir Grit Care Med 1994; 150:254-57
15. Taniguchi Y, Tamura G, Honma M, et al. The effect of an oral leukotriene antagonist, ONO-1078, on allergen-induced immediate bronchoconstriction in asthmatic subjects. J Allergy Clin Immunol 1993; 92:507-12
16. Fujimura M, Sakamoto S, Kamio Y, et al. Effect of a leukotriene antagonist, ONO-1078, on bronchial hyperresponsiveness in patients with asthma. Respir Med 1993; 87:133-38
17. 4) challenge in normal male subjects. Thorax (in press).
18. 4 antagonist, ONO-1078, on adult bronchial asthma in multicenter comparative double-blind clinical study with azelastine hydrochloride. J Clin Therapeut Med 1993; 9(suppl):71-107
19. Chand N, Sofia RD. Azelastine - a novel in vivo inhibitor of leukotriene biosynthesis: a possible mechanism of action: a mini review. J Asthma 1995; 32:227-34
20. Tinkelman DG, Bucholtz GA, Kemp JP, et al. Evaluation of the safety and efficacy of multiple doses of azelastine to adult patients with bronchial asthma over time. Am Rev Respir Dis 1990; 141:569-74