-
1
-
-
0029976253
-
DNA damage and apoptosis in Alzheimer's disease: Colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay
-
A.J. Anderson, J.H. Su and C.W. Cotman, DNA damage and apoptosis in Alzheimer's disease: Colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay, J. Neurosci. 16 (1996), 1710-1719.
-
(1996)
J. Neurosci.
, vol.16
, pp. 1710-1719
-
-
Anderson, A.J.1
Su, J.H.2
Cotman, C.W.3
-
2
-
-
0028129137
-
Evidence of an oxidative challenge in the Alzheimer's brain
-
L. Balazs and M. Leon, Evidence of an oxidative challenge in the Alzheimer's brain, Neurochem. Res. 19 (1994), 1131-1137.
-
(1994)
Neurochem. Res.
, vol.19
, pp. 1131-1137
-
-
Balazs, L.1
Leon, M.2
-
3
-
-
0027129818
-
Vitamin E protects nerve cells from amyloid β-protein toxicity
-
C. Behl, J. Davis, G.M. Cole and D. Schubert, Vitamin E protects nerve cells from amyloid β-protein toxicity, Biochem. Biophys. Res. Comm. 186 (1992), 944-950.
-
(1992)
Biochem. Biophys. Res. Comm.
, vol.186
, pp. 944-950
-
-
Behl, C.1
Davis, J.2
Cole, G.M.3
Schubert, D.4
-
4
-
-
0028207907
-
Amyloid β-peptide induces necrosis rather than apoptosis
-
C. Behl, J.B. Davis, F.G. Klier and D. Schubert, Amyloid β-peptide induces necrosis rather than apoptosis, Brain Res. 645 (1994), 253-264.
-
(1994)
Brain Res.
, vol.645
, pp. 253-264
-
-
Behl, C.1
Davis, J.B.2
Klier, F.G.3
Schubert, D.4
-
5
-
-
0028233494
-
Hydrogen peroxide mediates amyloid β-protein toxicity
-
C. Behl, J.B. Davis, R. Lesley and D. Schubert, Hydrogen peroxide mediates amyloid β-protein toxicity, Cell 77 (1994), 817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
6
-
-
0027526419
-
Release of excess amyloid β-protein from a mutant amyloid beta-protein precursor
-
X.-D. Cai, T. Golde and S. Younkin, Release of excess amyloid β-protein from a mutant amyloid beta-protein precursor, Science 259 (1993), 514-516.
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.-D.1
Golde, T.2
Younkin, S.3
-
7
-
-
0026075602
-
Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene
-
M.-C. Chartier-Harlin, F. Crawford, H. Houlden, A. Warren, D. Hughes, L. Fidani, A. Goate, M. Rossor, P. Roques, J. Hardy and M. Mullan, Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene, Nature 353 (1991), 844-846.
-
(1991)
Nature
, vol.353
, pp. 844-846
-
-
Chartier-Harlin, M.-C.1
Crawford, F.2
Houlden, H.3
Warren, A.4
Hughes, D.5
Fidani, L.6
Goate, A.7
Rossor, M.8
Roques, P.9
Hardy, J.10
Mullan, M.11
-
8
-
-
0026745610
-
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
-
M. Citron, T. Oltersorf, C. Haass, L. McConlogue, A.Y. Hung, P. Seubert, C. Vigo-Pelfrey, I. Lieberburg and D.J. Selkoe, Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production, Nature 360 (1992), 672-674.
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
9
-
-
0026513756
-
A histochemical study of iron, transferrin and ferritin in Alzheimer's diseased brains
-
J.R. Connor, S.L. Menzies, S.M. St.-Martin and E.J. Mufson, A histochemical study of iron, transferrin and ferritin in Alzheimer's diseased brains, J. Neurosci. Res. 31 (1992), 75-83.
-
(1992)
J. Neurosci. Res.
, vol.31
, pp. 75-83
-
-
Connor, J.R.1
Menzies, S.L.2
St.-Martin, S.M.3
Mufson, E.J.4
-
10
-
-
16044366039
-
Increased amyloid-β 42 (43) in brains of mice expressing mutant presenilin 1
-
K. Duff, C. Eckman, C. Zehr, X. Yu, C.-M. Prada, J. Perez-Tur, M. Hutton, L. Buee, Y. Harigaya, D. Yager, D. Morgan, M.N. Gordon, L. Holcomb, L. Refolo, B. Zenk, J. Hardy and S. Younkin, Increased amyloid-β 42 (43) in brains of mice expressing mutant presenilin 1, Nature 383 (1996), 710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
11
-
-
0028099622
-
Inflammatory mechanisms in Alzheimer's disease
-
P. Eikelenboom, S.-S. Zhan, W.A. van Gool and D. Allsop, Inflammatory mechanisms in Alzheimer's disease, TIPS 15 (1994), 447-450.
-
(1994)
TIPS
, vol.15
, pp. 447-450
-
-
Eikelenboom, P.1
Zhan, S.-S.2
Van Gool, W.A.3
Allsop, D.4
-
12
-
-
0028064502
-
Involvement of free oxygen radicals in beta-amyloidosis: An hypothesis
-
A.L. Friedlich and L.L. Butcher, Involvement of free oxygen radicals in beta-amyloidosis: An hypothesis, Neurobiol. Ageing 15 (1994), 443-455.
-
(1994)
Neurobiol. Ageing
, vol.15
, pp. 443-455
-
-
Friedlich, A.L.1
Butcher, L.L.2
-
13
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
A. Goate, M.-C. Chartier-Harlin, M. Mullan, J. Brown, F. Crawford, L. Fidani, L. Giuffra, A. Haynes, N. Irving, L. James, R. Mant, P. Newton, K. Rooke, P. Roques, C. Talbot, M. Pericak-Vance, A. Roses, R. Williamson, M. Rossor, M. Owen and J. Hardy, Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease, Nature 349 (1991), 704-706.
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
14
-
-
0027231535
-
Calretinin-immunorreactive neocortical interneurons are unaffected in Alzheimer's disease
-
P.R. Hof, E.A. Nimchinsky, M.R. Celio, C. Bouras and J.H. Morrison, Calretinin-immunorreactive neocortical interneurons are unaffected in Alzheimer's disease, Neurosci. Lett. 152 (1993), 145-149.
-
(1993)
Neurosci. Lett.
, vol.152
, pp. 145-149
-
-
Hof, P.R.1
Nimchinsky, E.A.2
Celio, M.R.3
Bouras, C.4
Morrison, J.H.5
-
15
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
K. Hsiao, P. Chapman, S. Nilsen, C. Eckman, Y. Harigaya, S. Younkin, F. Yang and G. Cole, Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice, Science 274 (1996), 99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
16
-
-
0028096241
-
Effects of nerve growth factor on catalase and glutathione peroxidase in a hydrogen peroxide-resistant pheochromocytoma subclone
-
G.R. Jackson, D. Sampath, K. Werrbach-Perez and R. Perez-Polo, Effects of nerve growth factor on catalase and glutathione peroxidase in a hydrogen peroxide-resistant pheochromocytoma subclone, Brain Res. 634 (1994), 69-76.
-
(1994)
Brain Res.
, vol.634
, pp. 69-76
-
-
Jackson, G.R.1
Sampath, D.2
Werrbach-Perez, K.3
Perez-Polo, R.4
-
17
-
-
0029073455
-
Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease
-
M.A. Lovell, W.D. Ehmann, S.M. Butler and W.R. Markesbury, Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease, Neurology 45 (1995), 1594-1601.
-
(1995)
Neurology
, vol.45
, pp. 1594-1601
-
-
Lovell, M.A.1
Ehmann, W.D.2
Butler, S.M.3
Markesbury, W.R.4
-
18
-
-
0030898724
-
An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease
-
L. Lyras, N.J. Cairns, A. Jenner, P. Jenner and B. Halliwell, An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease, J. Neurochem. 68 (1997), 2061-2069.
-
(1997)
J. Neurochem.
, vol.68
, pp. 2061-2069
-
-
Lyras, L.1
Cairns, N.J.2
Jenner, A.3
Jenner, P.4
Halliwell, B.5
-
19
-
-
0029610011
-
The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
-
P.L. McGeer and E.G. McGeer, The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases, Brain Res. Rev. 21 (1995), 195-218.
-
(1995)
Brain Res. Rev.
, vol.21
, pp. 195-218
-
-
McGeer, P.L.1
McGeer, E.G.2
-
20
-
-
0028152717
-
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
-
P. Mecocci, U. MacGarvey and M. Geal, Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease, Ann. Neurol. 36 (1994), 747-751.
-
(1994)
Ann. Neurol.
, vol.36
, pp. 747-751
-
-
Mecocci, P.1
MacGarvey, U.2
Geal, M.3
-
21
-
-
0021972548
-
Head injury as a risk factor for Alzheimer's disease
-
J.A. Mortimer, L.R. French, J.T. Hutton and L.M. Schuman, Head injury as a risk factor for Alzheimer's disease, Neurology 35 (1985), 264-267.
-
(1985)
Neurology
, vol.35
, pp. 264-267
-
-
Mortimer, J.A.1
French, L.R.2
Hutton, J.T.3
Schuman, L.M.4
-
22
-
-
0025950987
-
A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease
-
J. Murrell, M. Farlow, B. Ghetti and M.D. Benson, A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease, Science 254 (1991), 97-99.
-
(1991)
Science
, vol.254
, pp. 97-99
-
-
Murrell, J.1
Farlow, M.2
Ghetti, B.3
Benson, M.D.4
-
23
-
-
0026823074
-
Immunohistochemical evidence of antioxidant stress in Alzheimer's disease
-
M.A. Pappolla, R.A. Omar, K.S. Kim and N.K. Robakis, Immunohistochemical evidence of antioxidant stress in Alzheimer's disease, Am. J. Pathol. 140 (1992), 621-628.
-
(1992)
Am. J. Pathol.
, vol.140
, pp. 621-628
-
-
Pappolla, M.A.1
Omar, R.A.2
Kim, K.S.3
Robakis, N.K.4
-
24
-
-
0027447286
-
Neuro-degeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
-
C.J. Pike, D. Burdick, A.J. Walencewicz, C.G. Glabe and C.W. Cotman, Neuro-degeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state, J. Neurosci. 13 (1993), 1676-1687.
-
(1993)
J. Neurosci.
, vol.13
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
25
-
-
0030030030
-
Increased antioxidant enzyme activity Aβ-resistant cells
-
Y. Sagara, R. Dargusch, D. Schubert and C. Behl, Increased antioxidant enzyme activity Aβ-resistant cells, J. Neurosci. 16 (1996), 497-505.
-
(1996)
J. Neurosci.
, vol.16
, pp. 497-505
-
-
Sagara, Y.1
Dargusch, R.2
Schubert, D.3
Behl, C.4
-
26
-
-
0030967165
-
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease
-
M. Sano, C. Ernesto, R.G. Thomas, M.R. Klauber, K. Schafer, M. Grundman, P. Woodbury, J. Growdon, C.W. Cotman, E. Pfeiffer, L.S. Schneider and L.J. Thal, A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease, New Engl. J. Med. 336 (1997), 1216-1222.
-
(1997)
New Engl. J. Med.
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
Klauber, M.R.4
Schafer, K.5
Grundman, M.6
Woodbury, P.7
Growdon, J.8
Cotman, C.W.9
Pfeiffer, E.10
Schneider, L.S.11
Thal, L.J.12
-
28
-
-
0028118846
-
Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of β-amyloid-mediated cell death
-
M.S. Shearman, C.I. Ragan and L.L. Iversen, Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of β-amyloid-mediated cell death, Proc. Natl. Acad. Sci. USA 91 (1994), 1470-1474.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1470-1474
-
-
Shearman, M.S.1
Ragan, C.I.2
Iversen, L.L.3
-
29
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer's disease
-
M.A. Smith, P.L.R. Harris, L.M. Sayre, J.S. Beckman and G. Perry, Widespread peroxynitrite-mediated damage in Alzheimer's disease, J. Neurosci. 17 (1997), 2653-2657.
-
(1997)
J. Neurosci.
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Harris, P.L.R.2
Sayre, L.M.3
Beckman, J.S.4
Perry, G.5
-
30
-
-
0029982815
-
Oxidative damage in Alzheimer's
-
M.A. Smith, G. Perry, P.L. Richey, L.M. Sayre, V.E. Anderson, M.F. Beal and N. Kowall, Oxidative damage in Alzheimer's, Nature 382 (1996), 120-121.
-
(1996)
Nature
, vol.382
, pp. 120-121
-
-
Smith, M.A.1
Perry, G.2
Richey, P.L.3
Sayre, L.M.4
Anderson, V.E.5
Beal, M.F.6
Kowall, N.7
-
31
-
-
0025334082
-
Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro
-
K.V. Subarao, S. Richardson and L.C. Ang, Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro, J. Neurochem. 55 (1990), 342-345.
-
(1990)
J. Neurochem.
, vol.55
, pp. 342-345
-
-
Subarao, K.V.1
Richardson, S.2
Ang, L.C.3
-
32
-
-
0030809628
-
The role of protein phosphorylation in beta amyloid toxicity
-
S. Tan, P. Maher and D. Schubert, The role of protein phosphorylation in beta amyloid toxicity, Brain Res. 765 (1997), 159-163.
-
(1997)
Brain Res.
, vol.765
, pp. 159-163
-
-
Tan, S.1
Maher, P.2
Schubert, D.3
-
33
-
-
12644258498
-
The presenilin 2 mutation (N141I) linked to familial Alzheimer's disease (Volga German families) increases the secretion of amyloid β-protein ending at the 42nd (or 43rd) residue
-
T. Tomita, K. Maruyama, T.C. Saido, H. Kume, K. Shinozaki, S. Tokuhiro, A. Capell, J. Walter, J. Grunberg, C. Haass, T. Iwatsubo and K. Obata, The presenilin 2 mutation (N141I) linked to familial Alzheimer's disease (Volga German families) increases the secretion of amyloid β-protein ending at the 42nd (or 43rd) residue, Proc. Natl. Acad. Sci. USA 94 (1997), 2025-2030.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2025-2030
-
-
Tomita, T.1
Maruyama, K.2
Saido, T.C.3
Kume, H.4
Shinozaki, K.5
Tokuhiro, S.6
Capell, A.7
Walter, J.8
Grunberg, J.9
Haass, C.10
Iwatsubo, T.11
Obata, K.12
-
34
-
-
0013615899
-
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
-
S.D. Yan, X. Chen, J. Fu, M. Chen, H. Zhu, A. Roher, T. Slattery, L. Zhao, M. Nagashima, J. Morser, A. Migheli, P. Nawroth, D. Stern and A.M. Schmidt, RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease, Nature 382 (1996), 685-719.
-
(1996)
Nature
, vol.382
, pp. 685-719
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zhu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
35
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid β-protein: Reversal by tachykinin neuropeptides
-
B.A. Yankner, L.K. Duffy and D.A. Kirschner, Neurotrophic and neurotoxic effects of amyloid β-protein: reversal by tachykinin neuropeptides, Science 25 (1990), 279-282.
-
(1990)
Science
, vol.25
, pp. 279-282
-
-
Yankner, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
|