Enhancement of experimental allergic encephalomyelitis (EAE) by DNA immunization with myelin proteolipid protein (PLP) plasmid DNA

Journal of Neuropathology and Experimental Neurology

Volumn 57, Issue 8, 1998, Pages 758-767

  Tsunoda, Ikuo ^a   Kuang, Li Qing ^a   Tolley, Neal D ^a   Whitton, J Lindsay ^b   Fujinami, Robert S ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Autoimmune diseases; Autoimmunity; Demyelinating diseases; DNA immunization; EAE; Experimental allergic encephalomyelitis; Immunotherapy

Indexed keywords

COMPLEMENTARY DNA; IMMUNOGLOBULIN G ANTIBODY; PLASMID DNA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; DEMYELINATING DISEASE; EXPERIMENTAL MODEL; FEMALE; IMMUNIZATION; IMMUNOTHERAPY; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL;

EID: 0031870767     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199808000-00005     Document Type: Article

References (50)

1. Tsunoda I, Fujinami RS. Two models for multiple sclerosis: Experimental allergic encephalomyelitis and Theiler's murine encephalomyelitis virus. J Neuropathol Exp Neurol 1996;55:673-86
2. Fender MP. Experimental autoimmune encephalomyelitis. In: Pender MP, McCombe PA, eds. Autoimmune neurological disease. Cambridge: Cambridge University Press; 1995:25-88
3. - regulatory T cells and T cell clones presenting TCR peptide. Its implication for TCR vaccination against experimental autoimmune encephalomyelitis. J Immunol 1996;157: 1781-90
4. Waisman A, Ruiz PJ, Hirschberg DL, et al. Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity. Nat Med 1996;2:899-905
5. Barnett LA, Whitton JL, Wada Y, Fujinami RS. Enhancement of autoimmune disease using recombinant vaccinia virus encoding myelin proteolipid protein [published erratum appears in J Neuroimmunol 1993 Oct;48(1):120]. J Neuroimmunol 1993;44:15-25
6. Barnett LA, Whitton JL, Wang LY, Fujinami RS. Virus encoding an encephalitogenic peptide protects mice from experimental allergic encephalomyelitis. J Neuroimmunol 1996;64:163-73
7. Weiner HL. Oral tolerance: Immune mechanisms and treatment of autoimmune diseases. Immunol Today 1997;18:335-43
8. Whitacre CC, Gienapp IE, Meyer A, Cox KL, Javed N. Treatment of autoimmune disease by oral tolerance to autoantigens. Clin Immunol Immunopathol 1996;80:S31-S39
9. Pender MP. Multiple sclerosis. In: Pender MP, McCombe PA, eds. Autoimmune neurological disease. Cambridge: Cambridge University Press; 1995:89-154
10. Whitton JL, Oldstone MBA. Immune response to viruses. In: Fields BN, Knipe DM, Howley PM, eds. Fields virology. 3rd ed. Philadelphia: Lippincott-Raven Publishers; 1996:345-74
11. Rock KL, Gamble S, Rothstein L. Presentation of exogenous antigen with class I major histocompatibility complex molecules. Science 1990;249:918-21
12. Rock KL, Rothstein L, Gamble S, Fleischacker C. Characterization of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules. J Immunol 1993;150: 438-46
13. Kovacsovics-Bankowski M, Clark K, Benacerraf B, Rock KL. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl Acad Sci USA 1993;90:4942-46
14. Donnelly JJ, Ulmer JB, Hawe LA, et al. Targeted delivery of peptide epitopes to class I major histocompatibility molecules by a modified Pseudomonas exotoxin. Proc Natl Acad Sci USA 1993; 90:3530-34
15. Vitiello A, Ishioka G, Grey HM, et al. Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans. J Clin Invest 1995;95:341-49
16. Whitton JL, Yokoyama M. Proteins expressed by DNA vaccines induce both local and systemic immune responses. Ann N Y Acad Sci 1996;797:196-206
17. Whitton JL, Zhang J. Principles of cytotoxic T lymphocyte induction and recognition. Curr Top Microbiol Immunol 1995;202:247-59
18. Murphy BR, Chanock RM. Immunization against virus disease. In: Fields BN, Knipe DM, Howley PM, eds. Fields virology. Third edition. Philadelphia: Lippincott-Raven Publishers; 1996;467-97
19. Hassett DE, Zhang J, Whitton JL. Neonatal DNA immunization with a plasmid encoding an internal viral protein is effective in the presence of maternal antibodies and protects against subsequent viral challenge. J Virol 1997;71:7881-88
20. Tolley ND. DNA vaccination of SJL/J mice against Theiler's murine encephalomyelitis virus [master's thesis]. University of Utah; 1997
21. Hassett DE, Whitton JL. DNA immunization. Trends Microbiol 1996;4:307-12
22. Raz E, Tighe H, Sato Y, et al. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci USA 1996;93: 5141-45
23. Warrens AN, Zhang JY, Sidhu S, et al. Myoblasts fail to stimulate T cells but induce tolerance. Int Immunol 1994;6:847-53
24. Tuohy VK, Lu Z, Sobel RA, Laursen RA, Lees MB. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J Immunol 1989;142:1523-27
25. Greer JM, Kuchroo VK, Sobel RA, Lees MB. Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178-191) for SJL mice. J Immunol 1992;149:783-88
26. Yokoyama M, Zhang J, Whitton JL. DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection. J Virol 1995;69:2684-88
27. Tsunoda I, Iwasaki Y, Terunuma H, Sako K, Ohara Y. A comparative study of acute and chronic diseases induced by two subgroups of Theiler's murine encephalomyelitis virus. Acta Neuropathol (Berl) 1996;91:595-602
28. Rodriguez M, Lafuse WP, Leibowitz J, David CS. Partial suppression of Theiler's virus-induced demyelination in vivo by administration of monoclonal antibodies to immune-response gene products (Ia antigens). Neurology 1986;36:964-70
29. Rodriguez M, Quddus J. Effect of cyclosporin A, silica quartz dust, and protease inhibitors on virus-induced demyelination. J Neuroimmunol 1986;13:159-74
30. Amor S, Groome N, Linington C, et al. Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice. J Immunol 1994;153:4349-56
31. Lindsley MD, Thiemann R, Rodriguez M. Cytotoxic T cells isolated from the central nervous systems of mice infected with Theiler's virus. J Virol 1991;65:6612-20
32. Takács K, Chandler P, Altman DM. Relapsing and remitting experimental allergic encephalomyelitis: A focused response to the encephalitogenic peptide rather than epitope spread. Eur J Immunol 1997:27:2927-34
33. Tsunoda I, McCright IJ, Kuang LQ, Zurbriggen A, Fujinami RS. Hydrocephalus in mice infected with a Theiler's murine encephalomyelitis virus variant. J Neuropathol Exp Neurol 1997;56:1302-13
34. Lassmann H, Wisniewski HM. Chronic relapsing experimental allergic encephalomyelitis: Clinicopathological comparison with multiple sclerosis. Arch Neurol 1979;36:490-97
35. Wolff JA, Malone RW, Williams P, et al. Direct gene transfer into mouse muscle in vivo. Science 1990;247:1465-68
36. Hohlfeld R, Müller W, Toyka KV. Necrotizing myopathy in SJL mice [letter]. Muscle Nerve 1988;11:184-85
37. Gómez RM, Rinehart JE, Wollmann R, Roos RP. Theiler's murine encephalomyelitis virus-induced cardiac and skeletal muscle disease. J Virol 1996;70:8926-33
38. Windhagen A, Nicholson LB, Weiner HL, Kuchroo VK, Hafler DA. Role of Th1 and Th2 cells in neurologic disorders. Chem Immunol 1996;63:171-86
39. Lehmann PV, Forsthuber T, Miller A, Sercarz EE. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 1992;358:155-57
40. Miller SD, Karpus WJ. The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases. Immunol Today 1994;15: 356-61
41. Tuohy VK, Thomas DM. Sequence 104-117 of myelin proteolipid protein is a cryptic encephalitogenic T cell determinant for SJL/J mice. J Neuroimmunol 1995;56:161-70
42. Feltquate DM, Heaney S, Webster RG, Robinson HL. Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. J Immunol 1997;158:2278-84
43. Coffman RL, Seymour BW, Lebman DA, et al. The role of helper T cell products in mouse B cell differentiation and isotype regulation. Immunol Rev 1988;102:5-28
44. Snapper CM, Marcu KB, Zelazowski P. The immunoglobulin class switch: Beyond "accessibility". Immunity 1997;6:217-23
45. Tanuma N, Kojima T, Shin T, et al. Competitive PCR quantification of pro-and anti-inflammatory cytokine mRNA in the central nervous system during autoimmune encephalomyelitis. J Neuroimmunol 1997;73:197-206
46. Tanuma N, Matsumoto Y. Recent advances in the immunopathology of experimental autoimmune encephalomyelitis: With special reference to cytokine production in the central nervous system. Neuropathology 1997;17:152-59
47. Sobel RA, Greer JM, Kuchroo VK. Minireview: Autoimmune responses to myelin proteolipid protein. Neurochem Res 1994;19: 915-21
48. Torres CAT, Iwasaki A, Barber BH, Robinson HL. Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations. J Immunol 1997;158:4529-32
49. Corr M, Lee DJ, Carson DA, Tighe H. Gene vaccination with naked plasmid DNA. Mechanism of CTL priming. J Exp Med 1996;184: 1555-60
50. Iwasaki A, Torres CAT, Ohashi PS, Robinson HL, Barber BH. The dominant role of bone marrow-derived cells in CTL induction following plasmid DNA immunization at different sites. J Immunol 1997;159:11-14