Heterologous expression of various P-glycoproteins in polarized epithelial cells induces directional transport of small (type 1) and bulky (type 2) cationic drugs

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 1, 1998, Pages 321-327

  Smit, Johan W ^b   Weert, Betty ^a   Schinkel, Alfred H ^b   Meijer, Dirk K F ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALIPHATIC COMPOUND; AROMATIC COMPOUND; CATION; GLYCOPROTEIN P; METHYL IODIDE; PROCAINAMIDE; TRIBUTYLMETHYLAMMONIUM; VECURONIUM; VINBLASTINE;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CATION TRANSPORT; CELL MEMBRANE TRANSPORT; CELL POLARITY; CELL STRAIN; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISPOSITION; DRUG ELIMINATION; DRUG TRANSPORT; EPITHELIUM CELL; GENE EXPRESSION; KIDNEY EPITHELIUM; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL POLARITY; EPITHELIUM; P-GLYCOPROTEIN; QUATERNARY AMMONIUM COMPOUNDS; SWINE; VECURONIUM BROMIDE;

EID: 0031869860     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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