Retrovirus-mediated double transduction of the GTPCH and PTPS genes allows 6-pyruvoyltetrahydropterin synthase-deficient human fibroblasts to synthesize and release tetrahydrobiopterin

Journal of Neurochemistry

Volumn 71, Issue 1, 1998, Pages 33-40

  Laufs, Stephanie ^a   Blau, Nenad ^a   Thöny, Beat ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Gene transfer; Human fibroblasts; Hyperphenylalaninemia; Neurotransmitter depletion; Retrovirus; Tetrahydrobiopterin deficiency

Indexed keywords

DYSPROPTERIN; TETRAHYDROBIOPTERIN; VIRUS VECTOR;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; ENZYME DEFICIENCY; ENZYME RELEASE; ENZYME SYNTHESIS; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HYPERPHENYLALANINEMIA; NEUROTRANSMITTER RELEASE; PRIORITY JOURNAL; PROTEIN CONTENT; RETROVIRUS;

EID: 0031866959     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71010033.x     Document Type: Article

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