Toxicity of replication-defective adenoviral recombinants in dissociated cultures of nervous tissue

Experimental Neurology

Volumn 140, Issue 1, 1996, Pages 14-20

  Durham, Heather D ^a   Lochmüller, Hanns ^a   Jani, Agnes ^a,c   Acsadi, Gyula ^a,d   Massie, Bernard ^b   Karpati, George ^a  

^a MCGILL UNIVERSITY   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CHILDREN'S HOSPITAL OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; HUMAN; MITOSIS; MOUSE; NERVOUS TISSUE; NEUROTOXICITY; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION; SPINAL GANGLION; TISSUE CULTURE; TRANSGENE; VIRUS PARTICLE; VIRUS RECOMBINANT; VIRUS REPLICATION;

EID: 0030199247     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1996.0110     Document Type: Article

References (25)

1. 1. ACSADI, G., A. JANI, H. LOCHMÜLLER, J. HUARD, B. MASSIE, S. PRESCOTT, M. SIMONEAU, B. PETROF, AND G. KARPATI. 1996. Efficient dystrophin expression in muscles of mdx mice after adenovirus-mediated in vivo gene transfer. Hum. Gene Ther. 7: 129-140.
2. 2. ACSADI, G., A. JANI, B. MASSIE, M. SIMONEAU, P. HOLLAND, K. BLASCHUK, AND G. KARPATI. 1994. A differential efficiency of adenovirus-mediated in vivo gene transfer into skeletal muscle cells of different maturity. Hum. Mol. Genet. 3: 579-584.
3. 3. AKLI, S., C. CAILLAUD, E. VIGNE, L. K. STRATFORD-PERRICAUDET, L. POENARU, M. PERRICAUDET, A. KAHN, AND M. R. PESCHANSKI. 1993. Transfer of a foreign gene into the brain using adenovirus vectors. Nature Genet. 3: 224-228.
4. 4. BAJOCCHI, G., S. H. FELDMAN, R. G. CRYSTAL, AND A. MASTRANGELI. 1993. Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nature Genet. 3: 229-234.
5. 5. BYRNES, A. P., J. E. RUSBY, M. J. A. WOOD, AND H. M. CHARLTON. 1995. Adenovirus gene transfer causes inflammation in the brain. Neuroscience 66: 1015-1024.
6. 6. CAILLAUD, C., S. AKLI, E. VIGNE, A. KOULAKOFF, M. PERRICAUDET, L. POENARU, A. KAHN, AND Y. BERWALD-NETTER. 1993. Adenoviral vector as a gene delivery system into cultured rat neuronal and glial cells. Eur. J. Neurosci. 5: 1287-1291.
7. 7. DAVIDSON, B. L., E. D. ALLEN, K. F. KOZARSKY, J. M. WILSON, AND B. J. ROESSLER. 1993. A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nature Genet. 3: 219-223.
8. 8. DURHAM, H. D. 1992. An antibody against hyperphosphorylated neurofilament proteins collapses the neurofilament network in motor neurons but not in dorsal root ganglion cells. J. Neuropathol. Exp. Neurol. 51: 287-297.
9. 9. FISHER, L. J., AND J. RAY. 1994. In vivo and ex vivo gene transfer to the brain. Curr. Opin. Neurobiol. 4: 735-741.
10. 10. GHADGE, G. D., R. P. ROOS, U. J. KANG, R. WOLLMAN, P. S. RISHMAN, A. M. KALYNYCH, E. BARR, AND J. M. LEIDEN. 1995. CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses. Gene Ther. 2: 132-137.
11. 11. HALLAUER, P. L., H. L. BRADSHAW, AND K. E. M. HASTINGS. 1993. Complex fiber-type-specific expression of fast skeletal muscle troponin I gene constructs in transgenic mice. Development 119: 691-701.
12. 12. JOMARY, C., T. A. PIPER, G. DICKSON, L. A. COUTURE, A. E. SMITH, M. J. NEAL, AND S. E. JONES. 1994. Adenovirus-mediated gene transfer to murine retinal cells in vitro and in vivo. FEBS Lett. 347: 117-122.
13. 13. KARPATI, G., H. LOCHMÜLLER, J. NALBANTOGLU, AND H. DURHAM. 1996. The principles of gene therapy for the nervous system. Trends Neurosci. 19: 49-54.
14. 14. LE GAL LA SALLE, G., J. J. ROBERT, S. BERRARD, V. RIDOUX, L. D. STRATFORD-PERRICAUDET, M. PERRICAUDET, AND J. MALLET. 1993. An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259: 988-990.
15. 15. LISOVOSKI, F., J. CADUSSEAU, S. AKLI, C. CAILLAUD, E. VIGNE, L. POENARU, L. STRATFORD-PERRICAUDET, M. PERRICAUDET, A. KAHN, AND M. PESCHANSKI. 1994. In vivo transfer of a marker gene to study motoneuronal development. Neuroreport 5: 1069-1072.
16. 16. LOCHMÜLLER, H., A. JANI, J. HUARD, S. PRESCOTT, M. SIMONEAU, B. MASSIE, G. KARPATI, AND G. ACSADI. 1994. Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (delta-E1 + delta-E3) during multiple passages in 293 cells. Hum. Gene Ther. 5: 1485-1491.
17. 17. NEVE, R. L. 1993. Adenovirus vectors enter the brain. Trends Neurosci. 16: 251-253.
18. 18. RIDOUX, V., J. J. ROBERT, X. ZHANG, M. PERRICAUDET, J. MALLET, AND G. LE GAL LA SALLE. 1994. Adenoviral vectors as functional retrograde neuronal tracers. Brain Res. 648: 171-175.
19. 19. RIDOUX, V., J. J. ROBERT, X. ZHANG, M. PERRICAUDET, J. MALLET, AND G. LE GAL LA SALLE. 1994. The use of adenovirus vectors for intracerebral grafting of transfected nervous cells. Neuroreport 5: 801-804.
20. 20. SMITH, C. L., M. G. MEHAFFEY, D. B. DAYDA, J. M. SAUNDERS, S. YEI, B. C. TRAPNELL, A. MCCLELLAND, AND M. KALEKO. 1993. Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice. Nat. Genet. 5: 397-402.
21. 21. SUHR, S. T., AND F. H. GAGE. 1993. Gene therapy for neurologic disease. Arch. Neurol. 50: 1252-1268.
22. 22. WOLFF, J. A. 1993. Postnatal gene transfer into the central nervous system. Curr. Opin. Neurobiol. 3: 743-748.
23. 23. YANG, Y., F. A. NUNES, K. BERENCSI, E. E. FURTH, E. GÖNCZÖL, AND J. M. WILSON. 1994. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. USA 91: 4407-4411.
24. 24. YANG, Y., F. A. NUNES, K. BERENCSI, E. GÖNCZÖL, J. F. ENGELHARDT, AND J. M. WILSON. 1994. Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis. Nature Genet. 7: 362-369.
25. 25. ZABNER, J., L. A. COUTURE, R. J. GREGORY, S. M. GRAHAM, A. E. SMITH, AND M. J. WELSH. 1993. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell 75: 207-216.