Keeping pace with Neurospora circadian rhythms

Microbiology

Volumn 144, Issue 7, 1998, Pages 1699-1711

  Bell Pedersen, Deborah ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Circadian rhythms; Clock; Clock controlled genes (ccgs); Light entrainment; Neurospora crassa

Indexed keywords

CIRCADIAN RHYTHM; FUNGAL GENETICS; MOLECULAR BIOLOGY; NEUROSPORA CRASSA; NONHUMAN; PRIORITY JOURNAL; REVIEW;

NEUROSPORA; NEUROSPORA CRASSA;

EID: 0031856897     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-144-7-1699     Document Type: Review

References (144)

1. Abastado, J. P., Miller, P. F., Jackson, B. M. & Hinnebusch, A. G. (1991). Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control. Mol Cell Biol 11, 486-496.
2. Albrecht, U., Sun, Z. S., Eichele, G. & Lee, C. C. (1997). A differential response of two putative mammalian circadian regulators, mper1 and mper2 to light. Cell 91, 1055-1064.
3. Andersen, S. L. & Kay, S.A. (1997). Phototransduction and circadian clock pathways regulating gene transcription in higher plants. Adv Genet 35, 1-34.
4. Anderson, S. L., Teakle, G. R., Martino-Catt, S. J. & Kay, S. A. (1994). Circadian clock- and phytochrome-regukued transcription is conferred by a 78 bp cis-acting domain of the Arabidopsis CAB2 promoter. Plant J 6, 457-470.
5. Anderson, S. L., Somers, D. E., Millar, A. J., Hanson, K., Chory, J. & Kay, S. A. (1997). Attenuation of phytochrome A and B signaling pathways by the Arabidopsis circadian clock. Plant Cell 9, 1727-1743.
6. Aronson, B.D., Johnson, K. A. & Dunlap, J. C. (1994a). The circadian clock locus frequency: a single ORF defines period length and temperature compensation. Proc Natl Acad Sci USA 91, 7683-7687.
7. Aronson, B. D., Johnson, K. A., Loros, J. J. & Dunlap, J. C. (1994b). Negative feedback defining a circadian clock: autoregulation in the clock gene frequency. Science 263, 1578-1584.
8. Arpaia, G., Loros, J. J., Dunlap, J. C., Morelli, G. & Macino, G. (1993). The interplay of light and the circadian clock: independent dual regulation of clock-controlled gene ccg-2 (eas). Plant Physiol 102, 1299-1305.
9. Arpaia, G., Loros, J. J., Dunlap, J. C., Morelli, G. & Macino, G. (1995a). Light induction of the clock-controlled gene ccg-1 is not transduced through the circadian clock. Mol Gen Genet 247, 157-163.
10. Arpala, G., Carattoli, A. & Macino, G. (1995b). Light and development regulate the expression of the albino-3 gene in Neurospora crassa. Dev Biol 170, 626-635.
11. Ballarlo, P., Vittorioso, P., Magrelli, A., Talora, C., Cabibbo, A. & Macino, G. (1996). White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein. EMBO J 15, 1650-1657.
12. Bell-Pedersen, D., Dunlap, J. C. & Loros, J. J. (1992). The Neurospora circadian clock-controlled gene, ccg-2, is allelic to eas and encodes a fungal hydrophobin required for formation of the conidial rodlet layer. Genes Dev 6, 2382-2394.
13. Bell-Pedersen, D., Dunlap, J. C. & Loros, J. L. (1996a). Distinct cisacting elements mediate clock, light and developmental regulation of the Neurospora crassa eas (ccg-2) gene. Mol Cell Biol 16, 513-521.
14. Bell-Pedersen, D., Shinohara, M., Loros, J. J. & Dunlap, J. (1996b). Clock-controlled genes isolated from Neurospora crassa are late night- to morning-specific. Proc Natl Acad Sci USA 93, 13096-13101.
15. Bell-Pedersen, D., Garceau, N. & Loros, J. J. (1996c). Circadian rhythms in fungi. J Genet 75, 387-401.
16. Borgstahl, G. E., Williams, D. R. & Getzoff, E. D. (1995). 1·4 Å structure of photoactive yellow protein, a cytosolic photoreceptor : unusual fold, active site, and chromophore. Biochemistry 34, 6278-6287.
17. Borjigin, J., Wang, M. M. & Snyder, S. H. (1995). Diurnal variation in mRNA encoding serotonin N-acetyltransferase in pineal gland. Nature 378, 783-785.
18. Cahill, G. M. & Besharse, J. C. (1993). Circadian clock functions localized in Xenopus retinal photoreceptors. Neuron 10, 573-577.
19. Carpenter, C. D., Kreps, J. A. & Simon, A. E. (1994). Genes encoding glycine-rich Arabidopsis thaliana proteins with RNA-binding motifs are influenced by cold treatment and an endogenous circadian rhythm. Plant Physiol 104, 1015-1025.
20. Carre, I. A. & Kay, S. A. (1995). Multiple DNA-protein complexes at a circadian-regulated promoter element. Plant Cell 7, 2039-2051.
21. Cassone, V. M., Warren, W. S., Brooks, D. S. & Lu, J. (1993). Melatonin, the pineal gland, and circadian rhythms. J Biol Rhythms 8 (suppl.), S73-81.
22. Castiglione-Morelli, M. A., Guantieri, V., Villani, V., Kyriacou, C. P. & Tamburro, A. M. (1995). Conformational study of the Thr-Gly repeat in the Drosophila clock protein, PERIOD. Proc R Soc Lond Ser B Biol Sci 260, 155-163.
23. Chong, N. W., Cagampang, F. R., Coen, C. W., Campbell, I. C. & Powell, J. F. (1996). Rapid identification of novel genes expressed in a circadian manner in rat suprachiasmatic nuclei. Neuroreport 7, 1199-1203.
24. Cornelli, J., Taylor, W. R. & Hastings, J. W. (1994). An inhibitor of protein phosphorylation stops the circadian oscillator and blocks light-induced phase shifting in Gonyaulax polyedra. J Biol Rhythms 9, 13-26.
25. Crosthwaite, S. K., Loros, J. J. & Dunlap, J. C. (1995). Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript. Cell 81, 1003-1012.
26. Crosthwaite, S. K., Dunlap, J. C. & Loros, J. J. (1997). Neurospora wc-1 and wc-2: transcription, photoresponses, and the origins of circadian rhythmicity. Science 276, 763-769.
27. Curtin, K., Huang, J. & Rosbash, M. (1995). Temporally regulated entry of the Drosophila period protein contributes to the circadian clock. Neuron 14, 365-372.
28. Dharmananda, S. (1980). Studies of the circadian clock of Neurospora crassa: light-induced phase shifting. PhD thesis, University of California.
29. Dunlap, J. C (1993). Genetic analysis of circadian clocks. Anna Rev Physiol 55, 683-728.
30. Dunlap, J. C. (1996). Genetic and molecular analysis of circadian rhythms. Annu Rev Genet 30, 579-601.
31. Edery, I., Zweibel, L., Dembinska, M. & Rosbash, M. (1994). Temporal phosphorylation of the Drosophila period protein. Proc Natl Acad Sci USA 91, 2260-2264.
32. Edmunds, L. N. (1988). Cellular and Molecular Bases of Biological Clocks. New York : Springer.
33. Feldman, J. F. (1982). Genetic approaches to circadian clocks. Annu Rev Plant Physiol 33, 583-608.
34. Feldman, J. F. & Hoyle, M. N. (1973). Isolation of circadian clock mutants of Neurospora crassa. Genetics 75, 605-613.
35. Fonjallaz, P., Ossipow, V., Wanner, G. & Schibler, U. (1996). The two PAR leucine zipper proteins, TEF and DBP, display similar circadian and tissue-specific expression, but have different target promoter preferences. EMBO J 15, 351-362.
36. Francis, C. D. & Sargent, M. L. (1979). Effects of temperature perturbations on circadian conidiation in Neurospora. Plant Physiol 64, 1000-1004.
37. Fritz, B. H., Kasai, S. & Matsui, K. (1989). Free cellular riboflavin is involved in phase shifting the circadian clock of Neurospora crassa by light. Plant Cell Physiol 30, 557-564.
38. Fritz, B. H., Kasai, S. & Matsui, K. (1990). Blue light photoreception in Neurospora circadian rhythm: evidence for involvement of the flavin triplet state. Photochem Photobiol 51, 607-610.
39. Furuya, M. & Schafer, E. (1996). Photoperception and signaling of induction reactions by different phytochromes. Trends Plant Sci 1, 301-307.
40. Garceau, N. Y., Liu, Y., Loros, J. J. & Dunlap, J. C. (1997). Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY. Cell 89, 469-476.
41. L. Science 270, 811-815.
42. Goldbetter, A. (editor) (1996). Biochemical Oscillations and Cellular Rhythms. Cambridge: Cambridge University Press.
43. Golden, S. S., lshiura, M., Johnson, C. H. & Kondo, T. (1997). Cyanobacterial circadian rhythms. Annu Rev Plant Physiol Plant Mol Biol 48, 327-354.
44. Gooch, B. D., Wehseler, R. A. & Gross, C. G. (1994). Temperature effects on the resetting of the phase of the Neurospora circadian rhythm. J Biol Rhythms 9, 83-94.
45. Green, C B. & Besharse, J. C. (1996). Identification of a novel vertebrate circadian clock-regulated gene encoding the protein nocturnin. Proc Natl Acad Sci USA 93, 14884-14888.
46. Hall, J. C. & Kyriacou, C. P. (1990). Genetics of biological rhythms in Drosophila. Adv Insect Physiol 22, 221-298.
47. Hardin, P. E., Hall, J. C. & Rosbash, M. (1990). Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels. Nature 342, 536-540.
48. Hardin, P.E., Hall, J. C. & Rosbash, M. (1992). Circadian oscillations in period gene mRNA levels are transcriptionally regulated. Proc Natl Acad Sci USA 89, 11711-11715.
49. Harding, R. W. & Shropshire, W., Jr (1980). Photocontrol of carotenoid biosynthesis. Annu Rev Plant Physiol 31, 217-238.
50. Heintzen, C., Melzer, S., Fisher, R., Kappeler, S., Apel, K. & Staiger, D. (1994). A light- and temperature-entrained circadian clock controls expression of transcripts encoding nuclear proteins with homology to RNA-binding proteins in meristematic tissue. Plant J 5, 799-813.
51. Hicks, K. A., Millar, A. J., Carre, I. A., Somers, D. E., Straume, M., Meeks-Wagner, D. R. & Kay, S. A. (1996). Conditional circadian dysfunction of the Arabidopsis early flowering 3 mutant. Science 274, 790-792.
52. Huang, Z. J., Edery, I. & Rosbash, M. (1993). PAS is a dimerization domain common to Drosophila Period and several transcription factors. Nature 364, 259-262.
53. Huang, Z. J., Curtin, K. D. & Rosbash, M. (1995). PER protein interactions and temperature compensation of a circadian clock in Drosophila. Science 267, 1169-1172.
54. Hunter-Ensor, M., Ousely, A. & Sehgal, A. (1996). Regulation of the Drosophila protein TIMELESS suggests a mechanism for resetting the circadian clock by light. Cell 84, 677-685.
55. Ishida, N., Matsui, M., Nishimatsu, S., Murakami, K. & Mitsui, Y. (1994). Molecular cloning of a gene under control of the circadian clock and light in the rodent SCN. Mol Brain Res 26, 197-206.
56. Johnson, C. H. (1994). Illuminating the clock: circadian photobiology. Semin Cell Biol 5, 355-362.
57. King, D. P., Zhao, Y., Sangoram, A. M. & 9 other authors (1997). Positional cloning of the mouse circadian clock gene. Cell 89, 641-653.
58. Klein, D. C., Moore, R. Y. & Reppert, S. M. (editors) (1991). Suprachiasmatic Nucleus: The Mind's Clock. New York: Oxrford University Press.
59. Klemm, E. & Ninnemann, H. (1979). Photoreceptors for circadian rhythms. Photochem Photobiol Rev 4, 207-265.
60. Koh, M., Van Driessche, G., Samyn, B., Hoff, W. D., Meyer, T. E., Cusanovich, M. A. & Van Beeumen, J. J. (1996). Sequence evidence for strong conservation of the photoactive yellow proteins from the halophilic phototrophic bacteria Chromatium salexigens and Rhodospirillum salexigens. Biochemistry 35, 2526-2534.
61. Kondo, T. & Ishiura, M. (1994). Circadian rhythms of cyanobacteria: monitoring the biological clocks of individual colonies by bioluminescence. J Bacteriol 176, 1881-1885.
62. Kondo, T., Tsinoremas, N. F., Golden, S. S., Johnson, C. H., Kutsuna, S. & Ishiura, M. (1994). Circadian clock mutants of cyanobacteria. Science 266, 1233-1236.
63. Lakin-Thomas, P. L., Cote, G. G. & Brody, S. (1990). Circadian rhythms in Neurospora crassa: biochemistry and genetics. Crit Rev Microbiol 17, 365-416.
64. Lauter, F.-R. & Yanofsky, C. (1993). Day/night and circadian rhythm control of con gene expression in Neurospora. Proc Natl Acad Sci USA 90, 8249-8253.
65. Lauter, F.-R., Russo, V. E. & Yanofsky, C. (1992). Developmental and light regulation of eas, the structural gene for the rodlet protein of Neurospora. Genes Dev 6, 2373-2381.
66. Lavery, D. J. & Schibler, U. (1993). Circadian transcription of the cholesterol 7α. hydroxylase gene may involve the liver-enriched bZIP protein DBP. Genes Dev 7, 1871-1884.
67. Lee, C., Parikh, V., ltsukaichi, T., Bae, K. & Edery, I. (1996). Resetting the Drosophila clock by photic regulation of PER and a PER-TIM complex. Science 271, 1740-1744.
68. Levine, J. D., Sauman, I., Imbalzano, M., Reppert, S. M. & Jackson, F. R. (1995). Period protein from the giant silkmoth Antheraea pernyi functions as a circadian clock element in Drosophila melanogaster. Neuron 15, 147-157.
69. Lewis, M. T. & Feldman, J. F. (1993). The putative frq clock protein of Neurospora crassa contains sequence elements that suggest a nuclear transcriptional regulatory role. Protein Seq Data Anal 5, 315-323.
70. Lewis, M. T., Morgan, L. & Feldman, J. F. (1996). Analysis of frequency (frq) clock gene homologs: evidence for a helix-turn-helix transcription factor. Mol Gen Genet 253, 401-414.
71. Linden, H. & Macino, G. (1997). White collar-2, a partner in blue-light signal transduction, controlling expression of light-regulated genes in Neurospora crassa. EMBO J 16, 98-109.
72. Lindgren, K. M. (1994). Characterization of ccg-1, a clock-controlled gene of Neurospora crassa. PhD thesis, Dartmouth Medical School.
73. Liu, Y., Tsinoremas, N. F., Johnson, C. H., Lebedeva, N. V., Golden, S., lshiura, M. & Kondo, T. (1995). Circadian orchestration of gene expression in cyanobacteria. Genes Dev 9, 1469-1478.
74. Liu, Y., Garceau, N. Y., Loros, J. J. & Dunlap, J. C. (1997). Thermally regulated translational control of FRQ mediates aspects of temperature responses in the Neurospora circadian clock. Cell 89, 477-486.
75. Loros, J. (1995). The molecular basis of the Neurospora clock. Semin Neurosci 7, 3-13.
76. Loros, J. J. & Dunlap, J. C. (1991). Neurospora clock-controlled genes are regulated at the level of transcription. Mol Cell Biol 11, 558-563.
77. Loros, J. J., Richman, A. & Feldman, J. F. (1986). A recessive circadian clock mutant at the frq locus in Neurospora crassa. Genetics 114, 1095-1110.
78. Loros, J. J., Denome, S. A. & Dunlap, J. C. (1989). Molecular cloning of genes under control of the circadian clock in Neurospora. Science 243, 385-388.
79. Luo, C, Loros, J. J. & Dunlap, J. C. (1998). Nuclear localization is required for function of the essential clock protein FRQ. EMBO J 17, 1228-1235.
80. McClung, C. R., Fox, B. A. & Dunlap, J. C. (1989). The Neurospora clock gene frequency shares a sequence element with the Drosophila clock gene period. Nature 339, 558-562.
81. deMairan, J. J. (1729). Observation botanique. Hist Acad R Sci (Paris), p. 35.
82. Menaker, M. (1982). The search for principles of physiological organization in vertebrate circadian systems. In Vertebrate Circadian Systems : Structure and Physiology, pp. 1-12. Edited by J. Ascoff, S. Daan & G. A. Gross. Berlin: Springer.
83. Merrow, M. & Dunlap, J. C. (1994). Intergeneric complementation of a circadian rhythmicity defect: phylogenetic conservation of the 989 amino acid open reading frame in the clock gene frequency. EMBO J 13, 2257-2266.
84. Merrow, M., Garceau, N. Y. & Dunlap, J. C. (1997). Linearizing the circadian cycle to determine kinetic constants within the feedback loop. Proc Natl Acad Sci USA 94, 3877-3882.
85. Michel, S., Geusz, M., Zaritsky, J. & Block, G. (1993). Circadian rhythm in membrane conductance expressed in isolated neurons. Science 259, 239-241.
86. Millar, A. J., Carre, I. A., Strayer, C. A., Chua, N.-H. & Kay, S. A. (1995a). Circadian clock mutants in Arabidopsis identified by luciferase imaging. Science 267, 1161-1166.
87. Millar, A. J., Straume, M., Chory, J., Chua, N.-H. & Kay, S. A. (1995b). The regulation of circadian period by phototransduction pathways in Arabidopsis. Science 267, 1163-1166.
88. Mittag, M. (1996). Conserved circadian elements in phylogenetically diverse algae. Proc Natl Acad Sci USA 93, 14401-14404.
89. Mittag, M., Eckerskorn, C., Strupat, K. & Hastings, W. J. (1997). Differential translational initiation of lbp mRNA is caused by a 5′ upstream open reading frame. FEBS Lett 411, 245-250.
90. Molina, C. A., Foulkes, N. S., Lalli, E. & Sassone Corsi, P. (1993). Inducibility and negative autoregulation of CREM : an alternative promoter directs the expression of ICER, an early response represser. Cell 75, 875-886.
91. Moore-Ede, M., Sulzman, F. M. & Fuller, C. A. (1982). The Clocks That Time Us. Cambridge, MA: Harvard University Press.
92. Munger, K., Germann, U. A. & Lerch, K. (1987). Isolation and regulation of expression of the Neurospora crassa copper metallothionein gene. Exper Suppl 52, 393-399.
93. Myers, M., Wager-Smith, K., Rothenfluh-Hilfiker, A. & Young, M. (1996). Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock. Science 271, 1736-1740.
94. Nakashima, H. (1982). Phase shifting of the circadian clock by diethylstilbestrol and related compounds in Neurospora crassa. Plant Physiol 70, 982-986.
95. Nakashima, H. & Feldman, J. F. (1980). Temperature-sensitivity of light-induced phase shifting of the circadian clock of Neurospora. Photochem Photobiol 32, 247-251.
96. Paietta, J. & Sargent, M. L. (1981). Photoreception in Neurospora crassa: correlation of reduced light sensitivity with flavin deficiency. Proc Natl Acad Sci USA 78, 5573-5577.
97. Pierce, M. E., Sheshberadaran, H., Zhang, Z., Fox, L. E., Applebury, M. L & Takahashi, J. S. (1993). Circadian regulation of iodopsin gene expression in embryonic photoreceptors in retinal cell culture. Neuron 10, 579-586.
98. Pilgrim, M. L. & McClung, C. R. (1993). Differential involvement of the circadian clock in the expression of genes required for ribulose-1,5-bisphosphate carboxylase/oxygenase synthesis, assembly, and activation in Arabidopsis thaliana. Plant Physiol 103, 553-564.
99. Pilgrim, M. L., Caspar, T., Quail, P. H. & McClung, C. R. (1993). Circadian and light-regulated expression of nitrate reductase in Arabidopsis. Plant Mol Biol 23, 349-364.
100. Pittendrigh, C. S. (1960). Circadian rhythms and the circadian organization of living things. Cold Spring Harbor Symp Quant Biol 25, 159-184.
101. Pittendrigh, C. S., Bruce, B. G., Rosensweig, N. S. & Rubin, M. L. (1959). Growth patterns in Neurospora. Nature 184, 169-170.
102. van den Pol, A. N. & Dudek, F. E. (1993). Cellular communication in the circadian clock, the suprachiasmatic nucleus. Neuroscience 56, 793-811.
103. Ralph, M. & Menaker, M. (1988). A mutation of the circadian system in golden hamsters. Science 241, 1225-1227.
104. Ralph, M., Foster, R. G., Davis, F. C. & Menaker, M. (1990). Transplanted suprachiasmatic nucleus determines circadian period. Science 247, 975-978.
105. Rensing, L., Kallies, A., Gebauer, G. & Mohsenzadeh, S. (1995). The effects of temperature change on the circadian clock of Neurospora. Ciba Found Symp 183, 26-41.
106. Reppert, S. M., Tsai, T., Roca, A. L & Sauman, I. (1994). Cloning of a structural and functional homolog of the circadian clock gene period from the giant silkmoth Antheraea pernyi. Neuron 13, 1167-1176.
107. Robertson, L. M. & Takahashi, J. S. (1988). Circadian clock in cell culture. II. In vitro photic entrainment of melatonin oscillation from dissociated chick pineal cells. J Neurosci 8, 12-21.
108. Rosata, E., Trevisan, A., Sandrelli, F., Zordan, M., Kyriacou, C. & Costa, R. (1997). Conceptual translation of timeless reveals alternative initiating methionines. Nucleic Acids Res 25, 4.55-457.
109. Rosbash, M., Allada, R., Dembinska, M. & 7 other authors (1996). A Drosophila circadian clock. Cold Spring Harbor Symp Quant Biol 61, 265-278.
110. Rouyer, F., Rachidi, M., Pikielny, C. & Rosbash, M. (1997). A new gene encoding a putative transcription factor regulated by the Drosophila circadian clock. EMBO J 16, 3944-3954.
111. Rusak, B. & Bina, K. G. (1990). Neurotransmitters in the mammalian circadian system. Annu Rev Neurosci 13, 387-401.
112. Saez, L. & Young, M. W. (1996). Regulation of nuclear entry of Drosophila clock proteins PERIOD and TIMELESS. Neuron 17, 911-920.
113. Sargent, M. L., Briggs, W. R. & Woodward, D. O. (1966). Circadian nature of a rhythm expressed by an invertaseless strain of Neurospora crassa. Plant Physiol 41, 1343-1349.
114. Sauman, I. & Reppert, S. M. (1996). Circadian clock neurons in the silkmoth Antheraea pernyi: novel mechanisms of Period protein regulation. Neuron 17, 889-900.
115. Sehgal, A. (1995). Genetic dissection of the circadian clock: a timeless story. Semin Neurosci 7, 27-35.
116. Sehgal, A., Price, H., Man, B. & Young, M. (1994). Loss of circadian behavioral rhythms and per oscillations in the Drosophila mutant timeless. Science 263, 1603-1606.
117. Sehgal, A., Rothenfluh-Hilfiker, A., Hunter-Ensor, M., Chen, Y., Myers, M. & Young, M. W. (1995). Circadian oscillations and autoregulation of timeless RNA. Science 270, 808-810.
118. Shearman, L. P., Zylka, M. J., Weaver, D. R., Kolakowski, L. F., Jr & Reppert, S. M. (1997). Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei. Neuron 19, 1261-1269.
119. Shigeyoshi, Y., Taguchi, K., Yamamoto, S. & 8 other authors (1997). Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript. Cell 91, 1043-1053.
120. Shinohara, M. L., Loros, J. L. & Dunlap, J. C. (1998). Glyceraldehyde-3-phosphate dehydrogenase is regulated on a daily basis by the circadian clock. J Biol Chem 273, 446-450.
121. Silver, R., LeSauter, J., Tresco, P. A. & Lehman, M. N. (1996). A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms. Nature 382, 810-813.
122. Stehle, J. H., Foulkes, N. S., Molina, C. A., Slmoneaux, V., Pevet, P. & Sassone-Corsi, P. (1993). Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland. Nature 365, 314-319.
123. Stephan, F. K. & Zucker, I. (1972). Crcadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions. Proc Natl Acad Sci USA 69, 1583-1586.
124. Strecker, G. J., Bouskila, Y. & Dudek, F. E. (1995). Neurotransmission and electrophysiological mechanisms in the suprachiasmatic nucleus. Neurosciences 7, 43-51.
125. Sun, Z. S., Albrecht, U., Zhuchenki, O., Bailey, J., Eichele, G. & Lee, C. C. (1997). RIGUI, a putative mammalian ortholog of the Drosophila period gene. Cell 90, 1003-1011.
126. Sweeney, B. M. (1987). Rhythmic Phenomena in Plants, 2nd edn. San Diego: Academic Press.
127. Sweeney, B. M. & Borgese, M. B. (1989). A circadian rhythm in cell division in a prokaryote, the cyanobacterium Synechococcus WH7803. J Phycol 25, 183-186.
128. Takahashi, J. S. (1993). Circadian-clock regulation of gene expression. Curr Opin Genet Dev 3, 301-309.
129. Takahashi, J. S., Murakami, N., Nikaido, S. S., Pratt, B. L. & Robertson, L. M. (1989). The avian pineal, a vertebrate model system of the circadian oscillator: cellular regulation of circadian rhythms by light, second messengers, and macromolecular synthesis. Recent Prog Horm Res 45, 279-352.
130. Tei, H., Okamura, H., Shigeyoshi, Y., Fukuhara, C., Ozawa, R., Hirose, M. & Sakaki, Y. (1997). Circadian oscillation of a mammalian homologue of the Drosophila period gene. Nature 389, 512-516.
131. Tosini, G. & Menaker, M. (1996). Circadian rhythms in cultured mammalian retina. Science 272, 419-421.
132. Tsinoremas, N. F., lshiura, M., Kondo, T., Andersson, C. R., Tanaka, K., Takahashi, H., Johnson, C. H. & Golden, S. S. (1996). A sigma factor that modifies the circadian expression of a subset of genes in cyanobacteria. EMBO J 15, 2488-2495.
133. Turek, F. W. (1994). Circadian rhythms. Recent Prog Horm Res 49, 43-90.
134. Underwood, H. (1990). The pineal and melatonin: regulators of circadian function in lower vertebrates. Experientia 46, 120-128.
135. Van Gelder, R. N. & Krasnow, M. A. (1996). A novel circadianly expressed Drosophila melanogaster gene dependent on the period gene for its rhythmic expression. EMBO J 15, 1625-1631.
136. Van Gelder, R., Bae, H., Palazzolo, M. & Krasnow, M. A. (1995). Extent and character of circadian gene expression in Drosophila melanogaster: identification of 20 oscillating mRNAs in the fly head. Curr Biol 5, 1424-1436.
137. Vitaterna, M. H., King, D. P., Chang, A.-M. &7 other authors (1994). Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 264, 719-725.
138. Welsh, D. K., Logothetis, D. E., Meister, M. & Reppert, S. M. (1995). Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14, 697-706.
139. Zatz, M. (1992). Perturbing the pacemaker in the chick pineal. Discov Neurosci 8, 67-73.
140. Zatz, M. (1994). Photoendocrine transduction in cultured chick pineal cells. IV. What do vitamin A depletion and retinaldehyde addition do to the effects of light on the melatonin rhythm ? J Neurochem 62, 2001-2011.
141. Zatz, M., Mullen, D. A. & Moskal, J. R. (1988). Photoendocrine transduction in cultured chick pineal cells: effects of light, dark, and potassium on the melatonin rhythm. Brain Res 438, 199-215.
142. Zeng, H., Hardin, P. E. & Rosbash, M. (1994). Constitutive overexpression of the Drosophila period protein inhibits period mRNA cycling. EMBO J 13, 3590-3598.
143. Zeng, H., Qian, Z., Myers, M. & Rosbash, M. (1996). A light-entrainment mechanism for the Drosophila circadian clock. Nature 380, 129-135.
144. Zweibel, L. J., Pe, H., Liu, X., Hall, J. C. & Rosbash, M. (1991). A post-transcriptional mechanism contributes to circadian cycling of a per-B-galactosidase fusion protein. Proc Natl Acad Sci USA 88, 3882-3886.