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Volumn 10, Issue 1, 1996, Pages

Rational approaches to resistance: Using saquinavir

Author keywords

Cross resistance; HIV protease inhibitors; Resistance; Saquinavir

Indexed keywords

PROTEINASE INHIBITOR; SAQUINAVIR;

EID: 0029806127     PISSN: 13502840     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (42)

References (16)
  • 1
    • 0029644513 scopus 로고
    • Safely and activity of saquinavir in HIV infection
    • Kitchen VS, Skinner C, Ariyoshi K, et al.: Safely and activity of saquinavir in HIV infection. Lancet 1995, 345:952-955.
    • (1995) Lancet , vol.345 , pp. 952-955
    • Kitchen, V.S.1    Skinner, C.2    Ariyoshi, K.3
  • 2
    • 1842494259 scopus 로고
    • Saquinavir monotherapy trial: Prolonged suppression of viral load and resistance mutations with higher dosage
    • San Franscisco, September [abstract LB-5]
    • Shapiro JM, Winters MA, Kozal MJ, et al.: Saquinavir monotherapy trial: prolonged suppression of viral load and resistance mutations with higher dosage. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Franscisco, September 1995, 8 [abstract LB-5].
    • (1995) 35th Interscience Conference on Antimicrobial Agents and Chemotherapy , pp. 8
    • Shapiro, J.M.1    Winters, M.A.2    Kozal, M.J.3
  • 3
    • 0030201562 scopus 로고    scopus 로고
    • A randomized controlled trial of a protease inhibitor (saquinavir) in combination with zidovudine in previously untreated patients with advanced HIV infection
    • Vella S, Lazzarin A, Carosi G, et al.: A randomized controlled trial of a protease inhibitor (saquinavir) in combination with zidovudine in previously untreated patients with advanced HIV infection. Antiviral Ther 1996, 1:129-140.
    • (1996) Antiviral Ther , vol.1 , pp. 129-140
    • Vella, S.1    Lazzarin, A.2    Carosi, G.3
  • 4
    • 2442723342 scopus 로고    scopus 로고
    • Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine
    • Collier AC, Coombs RW, Schoenfeld DA, et al.: Treatment of human immunodeficiency virus infection with saquinavir, zidovudine, and zalcitabine. N Engl J Med 1996, 334:1011-1017.
    • (1996) N Engl J Med , vol.334 , pp. 1011-1017
    • Collier, A.C.1    Coombs, R.W.2    Schoenfeld, D.A.3
  • 5
    • 0003308625 scopus 로고    scopus 로고
    • Improved survival and decreased progression of HIV in patients treated with saquinavir (Invirase™,SQV) plus HIVID (zalcitabine, ddC)
    • Vancouver, July [abstract LB.B.6033]
    • Lalezari J, Haubrich R, Burger HU, et al.: Improved survival and decreased progression of HIV in patients treated with saquinavir (Invirase™,SQV) plus HIVID (zalcitabine, ddC). XI International Conference on AIDS. Vancouver, July 1996 [abstract LB.B.6033].
    • (1996) XI International Conference on AIDS
    • Lalezari, J.1    Haubrich, R.2    Burger, H.U.3
  • 6
    • 0029824426 scopus 로고    scopus 로고
    • In vivo resistance to a human immunodeficiency virus type 1 protease inhibitor: Mutations, kinetics and frequencies
    • Jacobsen H, Hanggi M, Ott M, et al.: In vivo resistance to a human immunodeficiency virus type 1 protease inhibitor: mutations, kinetics and frequencies. J Infect Dis 1996, 173:1379-1387.
    • (1996) J Infect Dis , vol.173 , pp. 1379-1387
    • Jacobsen, H.1    Hanggi, M.2    Ott, M.3
  • 7
    • 0029133978 scopus 로고
    • Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors
    • Tisdale M, Myers RE, Maschera B, et al.: Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors. Antimicrob Agents Chemother, 1995, 39:1704-1710.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 1704-1710
    • Tisdale, M.1    Myers, R.E.2    Maschera, B.3
  • 8
    • 0028854676 scopus 로고
    • Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor
    • Markowitz M, Mo H, Kempf DJ, et al.: Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor. J Virol 1995, 69:701-706.
    • (1995) J Virol , vol.69 , pp. 701-706
    • Markowitz, M.1    Mo, H.2    Kempf, D.J.3
  • 9
    • 0029092503 scopus 로고
    • In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease
    • Partaledis JA, Yamaguchi K, Tisdale M, et al.: In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease. J Virol 1995, 69:5228-5235.
    • (1995) J Virol , vol.69 , pp. 5228-5235
    • Partaledis, J.A.1    Yamaguchi, K.2    Tisdale, M.3
  • 10
    • 0029614884 scopus 로고
    • Drug-resistance patterns of saquinavir and other HIV protease inhibitors
    • Roberts NA: Drug-resistance patterns of saquinavir and other HIV protease inhibitors. AIDS 1995, 9 (suppl 1):S27-S32.
    • (1995) AIDS , vol.9 , Issue.1 SUPPL.
    • Roberts, N.A.1
  • 11
    • 0028855166 scopus 로고
    • Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance
    • Mellors JW, Larder BA, Schinazi RF: Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance. Int Antiviral News 1995, 3:8-13.
    • (1995) Int Antiviral News , vol.3 , pp. 8-13
    • Mellors, J.W.1    Larder, B.A.2    Schinazi, R.F.3
  • 12
    • 0028943992 scopus 로고
    • In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
    • Condra JH, Schleif WA, Blahy OM, et al.: In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature 1995, 374:569-571.
    • (1995) Nature , vol.374 , pp. 569-571
    • Condra, J.H.1    Schleif, W.A.2    Blahy, O.M.3
  • 13
    • 8544269494 scopus 로고    scopus 로고
    • Long term treatment with saquinavir does not lead to a significant reduction in sensitivity to MK-639
    • Vancouver, July [abstract 2792]
    • Race E, Gilbert SM, Tomlinson PW, et al.: Long term treatment with saquinavir does not lead to a significant reduction in sensitivity to MK-639. XI International Conference on AIDS. Vancouver, July 1996 [abstract 2792].
    • (1996) XI International Conference on AIDS
    • Race, E.1    Gilbert, S.M.2    Tomlinson, P.W.3
  • 14
    • 0008423276 scopus 로고    scopus 로고
    • In vitro growth characteristics of HIV-1 variants with reduced sensitivity to saquinavir explain the appearance of L90M escape mutant in vivo
    • abstract 85
    • Maschera B, Tisdale M, Darby G, Mayer R, Thai G, Blair ED: In vitro growth characteristics of HIV-1 variants with reduced sensitivity to saquinavir explain the appearance of L90M escape mutant in vivo [abstract 85]. Antiviral Ther 1996, 1 (suppl 1):53-54.
    • (1996) Antiviral Ther , vol.1 , Issue.1 SUPPL. , pp. 53-54
    • Maschera, B.1    Tisdale, M.2    Darby, G.3    Mayer, R.4    Thai, G.5    Blair, E.D.6
  • 15
    • 9344234180 scopus 로고
    • Specific mutations in HIV-1 protease that confer diminished susceptibility to ABT-538
    • San Francisco, September [abstract 1282]
    • Gao Q, Stewart K, Park C, et al.: Specific mutations in HIV-1 protease that confer diminished susceptibility to ABT-538 . 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, September 1995 [abstract 1282].
    • (1995) 35th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Gao, Q.1    Stewart, K.2    Park, C.3
  • 16
    • 15444377672 scopus 로고    scopus 로고
    • Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
    • Molla A, Korneyeva M, Gao Q, et al.: Ordered accumulation of mutations in HIV protease confers resistance to ritonavir. Nat Med 1996, 2:760-766.
    • (1996) Nat Med , vol.2 , pp. 760-766
    • Molla, A.1    Korneyeva, M.2    Gao, Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.