Cyclin D3-associated kinase activity is regulated by p27(kip1) in BALB/c 3T3 cells

Molecular Biology of the Cell

Volumn 9, Issue 8, 1998, Pages 2081-2092

  Dong, Feng ^a,b   Agrawal, Deepak ^a,b   Bagui, Tapan ^a,b   Pledger, W J ^a,b  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D3; CYCLINE; PROTEIN KINASE; PROTEIN P27; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELL CYCLE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME SPECIFICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION;

EID: 0031856518     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.9.8.2081     Document Type: Article

References (59)

1. kip during mitosis in BALB/c 3T3 cells. Cell Growth Differ. 6, 1199-1205.
2. kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells. Mol. Cell. Biol. 16, 4327-4336.
3. Baldin, V., Lukas, J., Marcote, M.J., Pagano, M., and Draetta, G. (1993). Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev. 7, 812-821.
4. Blain, S.W., Montalvo, E., and Massague, J. (1997). Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4. J. Biol. Chem. 272, 25863-25872.
5. Booher, R.N., Alfa, C.E., Hyams, J.S., and Beach, D.H. (1989). The fission yeast cdc2/cdc13/suc1 protein kinase: regulation of catalytic activity and nuclear localization. Cell 58, 485-497.
6. Cheng, M., Sexl, V., Sherr, C.J., and Roussel, M.F. (1998). Assembly of cyclin D-dependent kinase and titration of p27(Kip1) regulated by mitogen-activated protein kinase kinase [In Process Citation]. Proc. Natl. Acad. Sci. USA 95, 1091-1096.
7. Coats, S., Flanagan, W.M., Nourse, J., and Roberts, J.M. (1996). Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle. Science 272, 877-880.
8. Dong, F., Cress, W.D., Jr., Agrawal, D., and Pledger, W.J. (1998). The role of cyclin D3-dependent kinase in the phosphorylation of p130 in mouse BALB/c 3T3 fibroblasts. J. Biol. Chem. 273, 6190-6195.
9. Draetta, G., Luca, F., Westendorf, J., Brizuela, L., Ruderman, J., and Beach, D. (1989). Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF. Cell 56, 829-838.
10. Ducommun, B., Brambilla, P., Felix, M.A., Franza, B.R., Jr., Karsenti, E., and Draetta, G. (1991). cdc2 phosphorylation is required for its interaction with cyclin. EMBO J. 10, 3311-3319.
11. Dulic, V., Kaufmann, W.K., Wilson, S.J., Tlsty, T.D., Lees, E., Harper, J.W., Elledge, S.J., and Reed, S.I. (1994). p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76, 1013-1023.
12. el-Deiry, W.S., Tokino, T., Velculescu, V.E., Levy, D.B., Parsons, R., Trent, J.M., Lin, D., Mercer, W.E., Kinzler, K.W., and Vogelstein, B. (1993). WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825.
13. Elledge, S.J., and Harper, J.W. (1994). Cdk inhibitors: on the threshold of checkpoints and development. Curr. Opin. Cell Biol. 6, 847-852.
14. Fisher, R.P., and Morgan, D.O. (1994). A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase. Cell 78, 713-724.
15. Gould, K.L., Moreno, S., Owen, D.J., Sazer, S., and Nurse, P. (1991). Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. EMBO J. 10, 3297-3309.
16. Hadwiger, J.A., Wittenberg, C., Richardson, H.E., de Barros Lopes, M., and Reed, S.I. (1989). A family of cyclin homologs that control the G1 phase in yeast. Proc. Natl. Acad. Sci. USA 86, 6255-6259.
17. Hagan, L, Hayles, J., and Nurse, P. (1988). Cloning and sequencing of the cyclin-related cdc13+ gene and a cytological study of its role in fission yeast mitosis. J. Cell Sci. 91, 587-595.
18. Harper, J.W., Adami, G.R., Wei, N., Keyomarsi, K., and Elledge, S.J. (1993). The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816.
19. Harper, J.W., et al. (1995). Inhibition of cyclin-dependent kinases by p21. Mol. Biol. Cell 6, 387-400.
20. Hauser, P.J., Agrawal, D., Flanagan, M., and Pledger, W.J. (1997). The role of p27kip1 in the in vitro differentiation of murine keratinocytes. Cell Growth Differ. 8, 203-211.
21. Hengst, L., Dulic, V., Slingerland, J.M., Lees, E., and Reed, S.I. (1994). A cell cycle-regulated inhibitor of cyclin-dependent kinases. Proc. Natl. Acad. Sci. USA 91, 5291-5295.
22. Kato, A., Takahashi, H., Takahashi, Y., and Matsushime, H. (1997). Contact inhibition-induced inactivation of the cyclin D-dependent kinase in rat fibroblast cell line, 3Y1. Leukemia 11(suppl 3), 361-362.
23. Kato, J.Y., and Sherr, C.J. (1993). Inhibition of granulocyte differentiation by G1 cyclins D2 and D3 but not Dl. Proc. Natl. Acad. Sci. USA 90, 11513-11517.
24. Kitagawa, M., et al. (1996). The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2. EMBO J. 15, 7060-7069.
25. Kiyokawa, H., Kineman, R.D., Manova-Todorova, K.O., Soares, V.C., Hoffman, E.S., Ono, M., Khanam, D., Hayday, A.C., Frohman, L.A., and Koff, A. (1996). Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell 85, 721-732.
26. LaBaer, J., Garrett, M.D., Stevenson, L.F., Slingerland, J.M., Sandhu, C., Chou, H.S., Fattaey, A., and Harlow, E. (1997). New functional activities for the p21 family of CDK inhibitors. Genes Dev. 11, 847-862.
27. Lee, M.H., Reynisdottir, I., and Massague, J. (1995). Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev. 9, 639-649.
28. Matsuoka, M., Kato, J.Y., Fisher, R.P., Morgan, D.O., and Sherr, C.J. (1994). Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase. Mol. Cell. Biol. 14, 7265-7275.
29. Matsuoka, S., Edwards, M.C., Bai, C., Parker, S., Zhang, P., Baldini, A., Harper, J.W., and Elledge, S.J. (1995). p57kip2, a structurally distinct member of the p21cip1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes Dev. 9, 650-662.
30. Matsushime, H., Ewen, M.E., Strom, D.K., Kato, J.Y., Hanks, S.K., Roussel, M.F., and Sherr, C.J. (1992). Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins. Cell 71, 323-334.
31. Matsushime, H., Quelle, D.E., Shurtleff, S.A., Shibuya, M., Sherr, C.J., and Kato, J.Y. (1994). D-type cyclin-dependent kinase activity in mammalian cells. Mol. Cell. Biol. 14, 2066-2076.
32. Meyerson, M., and Harlow, E. (1994). Identification of G1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol. 14, 2077-2086.
33. Moreno, S., Hayles, J., and Nurse, P. (1989). Regulation of p34cdc2 protein kinase during mitosis. Cell 58, 361-372.
34. Morgan, D.O. (1995). Principles of CDK regulation. Nature 374, 131-134.
35. Nakanishi, M., Robetorye, R.S., Adami, G.R., Pereira-Smith, O.M., and Smith, J.R. (1995). Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/CIP1/WAF1. EMBO J. 14, 555-563.
36. Nourse, J., Firpo, E., Flanagan, W.M., Coats, S., Polyak, K., Lee, M.H., Massague, J., Crabtree, G.R., and Roberts, J.M. (1994). Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature 372, 570-573.
37. Picard, A., Capony, J.P., Brautigan, D.L., and Doree, M. (1989). Involvement of protein phosphatases 1 and 2A in the control of M phase-promoting factor activity in starfish. J. Cell Biol. 109, 3347-3354.
38. Polyak, K., Kato, J.Y., Solomon, M.J., Sherr, C.J., Massague, J., Roberts, J.M., and Koff, A. (1994a). p27kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes Dev. 8, 9-22.
39. Polyak, K., Lee, M.H., Erdjument-Bromage, H., Koff, A., Roberts, J.M., Tempst, P., and Massague, J. (1994b). Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78, 59-66.
40. Pondaven, P., Meijer, L., and Beach, D. (1990). Activation of M-phase-specific histone H1 kinase by modification of the phosphorylation of its p34cdc2 and cyclin components. Genes Dev. 4, 9-17.
41. Poon, R.Y., Yamashita, K., Adamczewski, J.P., Hunt, T., and Shuttleworth, J. (1993). The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2. EMBO J. 12, 3123-3132.
42. Quelle, D.E., Ashmun, R.A., Shurtleff, S.A., Kato, J.Y., Bar-Sagi, D., Roussel, M.F., and Sherr, C.J. (1993). Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev. 7, 1559-1571.
43. Reynisdottir, I., and Massague, J. (1997). The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2. Genes Dev. 11, 492-503.
44. Rivard, N., L'Allemain, G., Bartek, J., and Pouyssegur, J. (1996). Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts. J. Biol. Chem. 271, 18337-18341.
45. Roberts, J.M. (1993). Turning DNA replication on and off. Curr. Opin. Cell Biol. 5, 201-206.
46. Schagger, H., Hagen, T., Roth, B., Brandt, U., Link, T.A., and von Jagow, G. (1990). Phospholipid specificity of bovine heart bc1 complex. Eur. J. Biochem. 190, 123-130.
47. Sherr, C.J. (1996). Cancer cell cycles. Science 274, 1672-1677.
48. Sherr, C.J., and Roberts, J.M. (1995). Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9, 1149-1163.
49. Solomon, M.J., Glotzer, M., Lee, T.H., Philippe, M., and Kirschner, M.W. (1990). Cyclin activation of p34cdc2. Cell 63, 1013-1024.
50. Solomon, M.J., Harper, J.W., and Shuttleworth, J. (1993). CAK, the p34cdc2 activating kinase, contains a protein identical or closely related to p40MO15. EMBO J. 12, 3133-3142.
51. Soos, T.J., Kiyokawa, H., Yan, J.S., Rubin, M.S., Giordano, A., De-Blasio, A., Bottega, S., Wong, B., Mendelsohn, J., and Koff, A. (1996). Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth Differ. 7, 135-146.
52. Swenson, K.I., Farrell, K.M., and Ruderman, J.V. (1986). The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes. Cell 47, 861-870.
53. Toyoshima, H., and Hunter, T. (1994). p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78, 67-74.
54. Winston, J., Dong, F., and Pledger, W.J. (1996). Differential modulation of G1 cyclins and the Cdk inhibitor p27kip1 by platelet-derived growth factor and plasma factors in density-arrested fibroblasts. J. Biol. Chem. 271, 11253-11260.
55. Winston, J.T., and Pledger, W.J. (1993). Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and -independent mechanisms. Mol. Biol. Cell 4, 1133-1144.
56. Won, K.A., Xiong, Y., Beach, D., and Gilman, M.Z. (1992). Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc. Natl. Acad. Sci. USA 89, 9910-9914.
57. Wuarin, J., and Nurse, P. (1996). Regulating S phase: CDKs, licensing and proteolysis. Cell 85, 785-787.
58. Xiong, Y., Connolly, T., Futcher, B., and Beach, D. (1991). Human D-type cyclin. Cell 65, 691-699.
59. Xiong, Y., Hannon, G.J., Zhang, H., Casso, D., Kobayashi, R., and Beach, D. (1993). p21 is a universal inhibitor of cyclin kinases. Nature 366, 701-704.