Interaction of oligodeoxynucleotides with mycobacteria: Implications for new therapeutic strategies

Antisense and Nucleic Acid Drug Development

Volumn 8, Issue 3, 1998, Pages 207-214

  Attia, S A ^a   Shepherd, V E ^a   Rosenblatt, M N ^a   Davidson, M K ^a   Hughes, J A ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCOBACTERIAL AGENT; DENDRIMER; ESTER; ETHAMBUTOL; OLIGODEOXYNUCLEOTIDE; PHOSPHOROTHIOIC ACID;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; DRUG DELIVERY SYSTEM; MYCOBACTERIUM; NONHUMAN; NUCLEIC ACID TRANSPORT; PRIORITY JOURNAL;

EID: 0031854474     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1998.8.207     Document Type: Article

References (27)

1. AKHTAR, S., BASU, S., WICKSTROM, E., and JULIANO, R.L. (1991). Interactions of antisense DNA oligonucleotide analogs with phospholipid membranes (liposomes). Nucleic Acids Res. 19, 5551-5559.
2. BENNETT, C.F., CHIANG, M.Y., CHAN, H., SHOEMAKER, J.E., and MIRABELLI, C.K. (1992). Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol. Pharmacol. 41, 1023-1033.
3. BIELINSKA, A., KUKOWSKA LATALLO, J.F., JOHNSON, J., TOMALIA, D.A., and BAKER, J.R. JR. (1996). Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers. Nucleic Acids Res. 24, 2176-2182.
4. CROOKE, S.T. (1996). Proof of mechanism of antisense drugs. Antisense Nucleic Acid Drug Dev. 6, 145-147.
5. DESHPANDE, D., TOLEDO VELASQUEZ, D., THAKKAR, D., LIANG, W., and ROJANASAKUL, Y. (1996). Enhanced cellular uptake of oligonucleotides by EGF receptor-mediated endocytosis in A549 cells. Pharm. Res. 13, 57-61.
6. FENTON, M.J., and VERMEULEN, W. (1996). Immunopathology of tuberculosis: Roles of macrophages and monocytes. Infect. Immun. 64, 683-690.
7. OILMAN, A.G., RALL, T.W., et al., eds. (1990). Goodman and Gilman's The Pharmacological Basis of Therapeutics. (Pergamon Press, Elmsford, NY).
8. HAENSLER, J., and SZOKA, F.C., JR. (1993). Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconj. Chem. 4, 372-379.
9. HASAN, Z., SCHLAX, C, KUHN, L., LEFKOVITS, I., YOUNG, D., THOLE, J., and PIETERS, J. (1997). Isolation and characterization of the mycobacterial phagosome: Segregation from the endosomal/lysosomal pathway. Mol. Microbiol. 24, 545-553.
10. HEYM, B., HONORE, N., TRUFFOT PERNOT, C., BANERGEE, A., SCHURRA, C., JACOBS, W.R. JR, VAN EMBDEN, J.D., GROSSET, J.H., and COLE, S.T. (1994). Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: A molecular study [see Comments]. Lancet 344, 293-298.
11. HUGHES, J.A., ARONSOHN, A.I., AVRUTSKAYA, A.V., and JULIANO, R.L. (1996). Evaluation of adjuvants that enhance the effectiveness of antisense oligodeoxynucleotides. Pharm. Res. 13, 404-410.
12. HUGHES, J.A., AVRUTSKAYA, A.V., and JULIANO, R.L. (1994). Influence of base composition on membrane binding and cellular uptake of 10-mer phosphorothioate oligonucleotides in Chinese hamster ovary (CHRC5) cells. Antisense Res. Dev. 4, 211-215.
13. JAYARAMAN, K., McPARLAND, K., MILLER, P., and TS'O, P.O.P. (1981). Selective inhibition of Escherichia coli protein synthesis and growth by nonionic oligonucleotides complementary to the 3′ end of 16S rRNA. Proc. Natl. Acad. Sci. USA 78, 1537-1541.
14. JONES, M.N., KASZUBA, M., REBOIRAS, M.D., LYLE, I.G., HILL, K.J., SONG, Y.-H., WILMOT, S.W., and CREETH, J.E. (1994). The targeting of phospholipid liposomes to bacteria. Biochim. Biophys. Acta 1196, 57-64.
15. KANDIMALLA, E.R., MANNING, A., ZHAO, Q., SHAW, D.R., BYRN, R.A., SASISEKHARAN, V., and AGRAWAL, S. (1997). Mixed backbone antisense oligonucleotides: Design, biochemical and biological properties of oligonucleotides containing 2′-5′-riboand 3′-5′ deoxyribonucleotide segments. Nucleic Acids Res. 25, 370-378.
16. LI, B., HUGHES, J.A., and PHILLIPS, M.I. (1997). Uptake and efflux of intact antisense phosphorothioate deoxyoligonucleotide directed against angiotensin receptors in bovine adrenal cells. Neurochem. Int. 31, 393-403.
17. LONNBERG, H., and VUORIO, E. (1996). Towards genomic drug therapy with antisense oligonucleotides. Ann. Med. 28, 511-522.
18. NAKAI, D., SEITA, T., TERASAKI, T., IWASA, S., SHOJI, Y., MIZUSHIMA, Y., and SUGIYAMA, Y. (1996). Cellular uptake mechanism for oligonucleotides: Involvement of endocytosis in the uptake of phosphodiester oligonucleotides by a human colorcctal adenocarcinoma cell line, HCT-15. J. Pharmacol. Exp. Ther. 278, 1362-1372.
19. NAKATA, K., ROM, W.N., HONDA, Y., CONDOS, R., KANE-GASAKI, S., CAO, Y., and WEIDEN, M. (1997). Mycobacterium tuberculosis enhances human immunodeficiency virus-1 replication in the lung. Am. J. Respir. Crit. Care Med. 155, 996-1003.
20. ORTALO MAGNE, A., LEMASSU, A., LANEELE, M.A., BARDOU, F., SILVE, G., GOUNON, P., MARCHAL, G., and DAFFE, M. (1996). Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species. J. Bacteriol. 178, 456-461.
21. POXON, S.W., MITCHELL, P.M., LIANG, E., and HUGHES, J.A. (1996). Dendrimer delivery of oligonucleotides. Drug Deliv. 3, 255-261.
22. RAPAPORT, E., LEVINA, A., METELEV, V., and ZAMECNIK, P.C. (1996). Antimycobacterial activities of antisense oligodeoxynucleotide phosphorothioates in drug-resistant strains. Proc. Natl. Acad. Sci. USA 93, 709-713.
23. SILVE, G., VALERO GUILLEN, P., QUEMARD, A., DUPONT, M.A., DAFFE, M., and LANEELLE, G. (1993). Ethambutol inhibition of glucose metabolism in mycobacteria: A possible target of the drug. Antimicrob. Agents Chemother. 37, 1536-1538.
24. TAO, L.F., MARX, K.A., WONGWIT, W., JIANG, Z., AGRAWAL, S., and COLEMAN, R.M. (1995). Uptake, intracellular distribution, and stability of oligodeoxynucleotide phosphorothioate by Schistosoma mansoni. Antisense Res. Dev. 5, 123-129.
25. TEMSAMANI, J., KUBERT, M., TANG, J., PADMAPRIYA, A., and AGRAWAL, S. (1994). Cellular uptake of oligodeoxynucleotide phosphorothioates and their analogs. Antisense Res. Dev. 4, 35-42.
26. WAGNER, R.W., and FLANAGAN, W.M. (1997). Antisense technology and prospects for therapy of viral infections and cancer. Mol. Med. Today 3, 31-38.
27. ZAMECNIK, P.C., and STEPHENSON, M.L. (1978). Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl. Acad. Sci. USA 75, 280-284.