Cellular uptake mechanism for oligonucleotides: Involvement of endocytosis in the uptake of phosphodiester oligonucleotides by a human colorectal adenocarcinoma cell line, HCT-15

Journal of Pharmacology and Experimental Therapeutics

Volumn 278, Issue 3, 1996, Pages 1362-1372

  Nakai, Daisuke ^a   Seita, Takeshi ^a   Terasaki, Tetsuya ^a   Iwasa, Susumu ^b   Shoji, Yoko ^c   Mizushima, Yutaka ^c   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^c ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 CHLOROMERCURIBENZOIC ACID; ANTISENSE OLIGONUCLEOTIDE; ARSENOSOBENZENE; CHLOROMERCURIBENZENESULFONIC ACID; CHLOROQUINE; DEXTRAN SULFATE; IODOPHENAZONE; LACTATE DEHYDROGENASE; MESSENGER RNA; MONENSIN; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; OLIGONUCLEOTIDE; TRANSFERRIN;

ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELLULAR DISTRIBUTION; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG BINDING SITE; DRUG UPTAKE; ENDOCYTOSIS; HELA CELL; HUMAN; HUMAN CELL; INTERNALIZATION; MEMBRANE BINDING; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE;

4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID; ADENOCARCINOMA; ANIONS; CELL COMPARTMENTATION; COLORECTAL NEOPLASMS; DOWN-REGULATION; ENDOCYTOSIS; GENES, MDR; HUMANS; ION CHANNELS; KINETICS; MICROSCOPY, CONFOCAL; OLIGONUCLEOTIDES, ANTISENSE; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0030426649     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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