Host resistance to intracellular infection: Mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification

Journal of Experimental Medicine

Volumn 188, Issue 2, 1998, Pages 351-364

  Hackam, David J ^a,b   Rotstein, Ori D ^b   Zhang, Wei Jian ^a,b   Gruenheid, Samantha ^c   Gros, Philippe ^c   Grinstein, Sergio ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Macrophage; Mycobacterium tuberculosis; Phagocytosis; Phagosome; Proton pump

Indexed keywords

ANIMAL CELL; ARTICLE; GENE MUTATION; HOST RESISTANCE; INFECTION PREVENTION; INFECTION RESISTANCE; KNOCKOUT MOUSE; MACROPHAGE ACTIVATION; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM BOVIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL;

ANIMALS; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; GENETIC PREDISPOSITION TO DISEASE; MACROPHAGES, PERITONEAL; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MYCOBACTERIUM BOVIS; PHAGOCYTOSIS; TUBERCULOSIS;

EID: 0031850526     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.2.351     Document Type: Article

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