'Isogaba Maware': Quality control of genome DNA by checkpoints

BioEssays

Volumn 20, Issue 5, 1998, Pages 391-399

  Kitazono, Ana ^a   Matsumoto, Tomohiro ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; CELL CYCLE; CHEMISTRY; DNA DAMAGE; DNA REPLICATION; FUNGAL GENE; GENETICS; MOLECULAR GENETICS; PHYSIOLOGY; REVIEW; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE; DNA DAMAGE; DNA REPLICATION; GENES, FUNGAL; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 0031839104     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-1878(199805)20:5<391::AID-BIES6>3.0.CO;2-R     Document Type: Review

References (80)

1. Hartwell L, Weinert T (1989) Checkpoints: Controls that ensure the order of cell cycle events. Science 246:629-633.
2. Weinert T, Hartwell L (1988) The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241:317-322.
3. Schiestl RH, Reynolds P, Prakash S, Prakash L (1989) Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage. Mol Cell Biol 9:1882-1896.
4. Weinert TA, Hartwell LH (1993) Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. Genetics 134:63-80.
5. Gravik B, Carson M, Hartwell L (1995) Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol Cell Biol 15:6128-6138.
6. Nugent CI, Hughes TR, Lue NF, Lundblad V (1996) Cdc13p: A single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance. Science 274:249-251.
7. Lydall D, Weinert T (1995) Yeast checkpoint genes in DNA damage processing: Implications for repair and arrest. Science 270:1488-1491.
8. Witkin EM (1991) Rec A protein in SOS response: Molestones and mysteries. Biochimie 73:133-141.
9. Griffiths DJF, Barbet NC, McCready S, Lehmann AR, Carr AM (1995) Fission yeast rad17: A homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins. EMBO J 14:5812-5823.
10. Enoch T, Carr AM, Nurse P (1992) Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev 6:2035-2046.
11. Rowley R, Young PG (1992) Checkpoint controls in Schizosaccharomyces pombe: rad1. EMBO J 11:1335-1342.
12. Al-Khodairy F, Carr AM (1992) DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J 11:1343-1350.
13. +, a fission yeast gene required for S-M and DNA damage checkpoints. Mol Gen Genet 254:389-399.
14. Murray J, Carr A, Lehmann A, Watts F (1991) Cloning and characterisation of the rad9 DNA repair gene from Schizosaccharomyces pombe. Nucleic Acids Res 19:3525-3531.
15. + checkpoint control gene. Proc Natl Acad Sci USA 93:13890-13895.
16. + gene product couples S phase to START and mitosis. Cell 74:371-382.
17. +. Cell 74:383-393.
18. Navas T, Zhou Z, Elledge SJ (1995) DNA Polymerase ε links the DNA replication machinery to the S phase checkpoint. Cell 80:29-39.
19. Navas T, Sanchez Y, Elledge S (1996) RAD9 and DNA polymerase ε form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae. Genes Dev 10:2632-2643.
20. Araki H, Leem SH, Phongdara A, Sugino A (1995) Dpb11, which interacts with DNA polymerase II (epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Proc Natl Acad Sci USA 92:11791-11795.
21. Sugimoto K, Shimomura T, Hashimoto K, Araki H, Sugino A, Matsumoto K (1996) Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast. Proc Natl Acad Sci USA 93:7048-7052.
22. Murakami H, Okayama H (1995) A kinase from fission yeast responsible for blocking mitosis in S phase. Nature 374:817-819.
23. Sanchez Y, Desany B, Jones W, Liu Q, Wang B, Elledge S (1996) Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271:357-360.
24. Sun Z, Fay D, Marini F, Foiani M, Stern D (1996) Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways. Genes Dev 10:395-406.
25. Zhou Z, Elledge S (1993) DUN1 encodes a protein kinase that controls the DNA damage response in yeast. Cell 75:1119-1127.
26. Kato R, Ogawa H (1994) An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae. Nucleic Acids Res 22:3104-3112.
27. Hari K, Santerre A, Sekelsky J, McKim K, Boyd J, Hawley S (1995) The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell 82:815-821.
28. Bentley N, Holtzman D, Flaggs G, Keegan K, DeMaggio A, Ford J, Hoekstra M, Carr A (1996) The Schizosaccharomyces pombe rad3 checkpoint gene. EMBO J 15:6641-6651.
29. Cimprich K, Shin T, Keith C, Schreiber S (1996) cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein. Proc Natl Acad Sci USA 93:2850-2855.
30. Savitsky K, Bar-Shira A, et al (1995) A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268:1749-1753.
31. Greenwell P, Kronmal S, Porter S, Gassenhuber J, Obermaier B, Petes T (1995) TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell 82:823-829.
32. Morrow D, Tagle D, Shiloh Y, Collins F, Hieter P (1995) TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82:831-840.
33. Keegan K, Holtzman D, Plug A, Christenson E, Brainerd E, Flaggs G, Bentley N, Taylor E, Meyn M, Moss S, Carr A, Ashley T, Hoekstra M (1996) The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. Genes Dev 10:2423-2437.
34. Jung M, Kondratyev A, Lee S, Dimtchev A, Dritschilo A (1997) ATM gene product phosphorylates IκB-α. Cancer Res 57:24-27.
35. Jung M, Zhang Y, Lee S, Dritschilo A (1995) Correction of a radiation sensitivity in ataxia telangiectacsia cells by a truncated IκB-α. Science 268:1619-1621.
36. Jorgensen T, Shiloh Y (1996) The ATM gene and the radiobiology of ataxia-telangiectasia. Int J Radiat Biol 69:527-537.
37. Xu Y, Baltimore D (1996) Dual roles of ATM in the cellular response to radiation and in cell growth control. Genes Dev 10:2401-2410.
38. Xu Y, Ashley T, Brainerd E, Bronxon R, Meyn M, Baltimore D (1996) Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes Dev 10:2411-2422.
39. Hartley K, Cell D, Smith G, Zhang H, Divecha N, Connelly M, Admon A, Lees-Miller S, Anderson C, Jackson S (1995) DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 82:849-856.
40. Gottlieb T, Jackson S (1993) The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen. Cell 72:131-142.
41. Brown E, Schreiber S (1996) A signaling pathway to translational control. Cell 86:517-520.
42. Enoch T, Nurse P (1990) Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell 60:665-673.
43. Lundgren K, Walworth N, Booher R, Dembski M, Kirschner M, Beach D (1991) mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell 64:1111-1122.
44. Hayles J, Nurse P (1995) A pre-start checkpoint preventing mitosis in fission yeast acts independently of p34cdc2 tyrosine phosphorylation. EMBO J 14:2760-2771.
45. Rhind N, Furnari B, Russell P (1997) Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast. Genes Dev 11:504-511.
46. O'Connell MJ, Raleigh JM, Verkade HM, Nurse P (1997) Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J 16:545-554.
47. Walworth N, Davey S, Beach D (1993) Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. Nature 363:368-371.
48. Walworth NC, Bernards R (1996) rad-Dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science 271:353-356.
49. Ford JC, Al-Khodairy F, Fotou E, Sheldrick KS, Griffiths DJ, Carr AM (1994) 14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast. Science 265:533-535.
50. Francesconi S, Grenon M, Bouvier D, Baldacci G (1997) p56chk1 protein kinase is required for the DNA replication checkpoint at 37°C in fission yeast. EMBO J 16:1332-1341.
51. Sorger PK, Murray AW (1992) S-phase feedback control in budding yeast independent of tyrosine phosphorylation of p34cdc28. Nature 355:365-368.
52. Amon A, Surana U, Muroff I, Nasmyth K (1992) Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae. Nature 355:368-371.
53. Yamamoto A, Guacci V, Koshland D (1996) Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). J Cell Biol 133:99-110.
54. Glotzer M (1995) The only way out of mitosis. Curr Biol 5:970-972.
55. King R, Deshaies RJ, Peters JM, Kirschner MJ (1996) How proteolysis drives the cell cycle. Science 274:1652-1659.
56. Cohen-Fix O, Peters J, Kirschner MW, Koshland D (1996) Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev 10:3081-3093.
57. Lim HH, Surana U (1996) Cdc20, a beta-transducin homologue, links RAD9-mediated G2/M checkpoint control to mitosis in Saccharomyces cerevisiae. Mol Gen Genet 253:138-148.
58. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D (1993) p21 is a universal inhibitor of cyclin kinases. Nature 366:701-704.
59. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825.
60. Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
61. Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ (1995) Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377:552-557.
62. Deng C, Zhang P, Harper JW, Elledge SJ, Leder P (1995) Mice lacking p21CIP/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82:675-684.
63. Kumagai A, Dunphy W (1995) Control of the Cdc2/cyclinB complex in Xenopus egg extracts arrested at G2/M checkpoint with DNA synthesis inhibitors. Mol Biol Cell 6:199-213.
64. Moreno S, Nurse P (1994) Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene. Nature 367:236-242.
65. Schwob E, Bohm T, Mendenhall MD, Nasmyth K (1994) The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae. Cell 79:233-244.
66. Peter M, Herskowitz I (1994) Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1. Science 265:1228-1231.
67. Jin P, Gu Y, Morgan DO (1996) Role of Inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells. J Cell Biol 134:963-970.
68. Blasina A, Paegle ES, McGowan CH (1997) The role of inhibitory phosphorylation of CDC2 following DNA replication block and radiation-induced damage in human cells. Mol Biol Cell 8:1013-1023.
69. Koonin E, Altschul S (1996) BRCA1 protein products: Functional motifs. Nature Genet 13:266-268.
70. Bork D, Hofmann K, Bucher P, Neuwald A, Altschul S, Koonin E (1997) A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J 11:68-76.
71. Monteiro A, August A, Hanafusa H (1996) Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc Natl Acad Sci USA 93:13595-13599.
72. Chapman M, Verma I (1996) Transcriptional activation by BRCA1. Nature 382:678-679.
73. Iwabuchi K, Bartel P, Li B, Marraccino R, Fields S (1994) Two cellular proteins that bind to wild-type but not mutant p53. Proc Natl Acad Sci USA 91:6098-6102.
74. Caldecott K, Mckeown C, Tucker J, Ljungquist S, Thompson L (1994) An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III. Mol Cell Biol 14:68-76.
75. Willson J, Wilson N, Watts FZ (1997) Isolation and characterization of the Schizosaccharomyces pombe rhp9: A gene required for the DNA damage checkpoint but not the replication checkpoint. Nucleic Acids Res 25:2138-2145.
76. Malkin D (1994) Germline p53 mutations and heritable cancer. Annu Rev Genet 28:443-465.
77. Ellis NA, Groden J, Ye T, Straughen J, Lennon DJ, Ciocci S, Proytcheva M, German J (1995) The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 83:655-666.
78. Yu CE, Oshima J, Fu YH, Wijsman EM, Hisama F, Alisch R, Matthews S, Nakura J, Miki T, Ouais S, Martin GM, Mulligan J, Schellenberg GD (1996) Positional cloning of the Werner's syndrome gene. Science 272:258-262
79. +, a fission yeast gene related to the Bloom's and Werner's syndrome genes is required for reversible S phase arrest. EMBO J 16:2682-2692
80. Scully R, Chen J, Plug A, Xiao Y, Weaver D, Feunteun J, Ashley T, Livingston DM (1997) Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 88:265-275.