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Volumn 19, Issue 2, 1998, Pages 121-124

Translocations, cancer and the puzzle of specificity

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELL CULTURE; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CHROMOSOME TRANSLOCATION; GENE FUSION; GENETIC LINKAGE; GENETIC RECOMBINATION; GENETIC SUSCEPTIBILITY; HUMAN; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; REVIEW; SARCOMA; TUMOR SUPPRESSOR GENE;

EID: 0031838697     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/475     Document Type: Review
Times cited : (93)

References (36)
  • 1
    • 0025951251 scopus 로고
    • Implicating the bcr/abl gene in the pathogenesis of Philadelphia Chromosome-positive human leukemia
    • Daley, G.Q. & Ben-Neriah, Y. Implicating the bcr/abl gene in the pathogenesis of Philadelphia Chromosome-positive human leukemia. Adv. Cancer Res. 57, 151-184 (1991).
    • (1991) Adv. Cancer Res. , vol.57 , pp. 151-184
    • Daley, G.Q.1    Ben-Neriah, Y.2
  • 3
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbits, T.H. Chromosomal translocations in human cancer. Nature 372, 143-149 (1994).
    • (1994) Nature , vol.372 , pp. 143-149
    • Rabbits, T.H.1
  • 5
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine, A.J. p53, the cellular gatekeeper for growth and division. Cell 88, 323-331 (1997).
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 6
    • 0029019659 scopus 로고
    • AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia
    • Nucifora, G. AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia. Stood 86, 1-14 (1995).
    • (1995) Stood , vol.86 , pp. 1-14
    • Nucifora, G.1
  • 7
    • 0031406578 scopus 로고    scopus 로고
    • Molecular genetics and pathogenesis of rhabdomyosarcoma
    • Barr, F.G. Molecular genetics and pathogenesis of rhabdomyosarcoma. J. Fed. Hemat. Oncol. 19, 483-491 (1997).
    • (1997) J. Fed. Hemat. Oncol. , vol.19 , pp. 483-491
    • Barr, F.G.1
  • 8
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda, T., van Deursen, J., Hiebert, S.W., Grosveld, G. & Downing, J.R. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84, 321-330 (1996).
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    Van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 9
    • 0030823151 scopus 로고    scopus 로고
    • The role of cytogenetics in the classification of soft tissue tumors
    • Dei Tos, A.P. & Dal Cin, P. The role of cytogenetics in the classification of soft tissue tumors. Virchows Arch. 431, 83-94 (1997).
    • (1997) Virchows Arch. , vol.431 , pp. 83-94
    • Dei Tos, A.P.1    Dal Cin, P.2
  • 10
    • 0027362619 scopus 로고
    • The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1
    • May, W.A. et al. The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Mol. Cell. Biol. 13, 7393-7398 (1993).
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7393-7398
    • May, W.A.1
  • 11
    • 0027970712 scopus 로고
    • A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP
    • Zinszner, H., Albalat, R. & Ron, D. A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP. Genes Dev. 8, 2513-2526 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 2513-2526
    • Zinszner, H.1    Albalat, R.2    Ron, D.3
  • 12
    • 0023263055 scopus 로고
    • The CML-specific P210 bcrlabl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts
    • Daley, G.Q., McLaughlin, J., Witte, O.N. & Baltimore, D. The CML-specific P210 bcrlabl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts. Science 237, 532-535 (1987).
    • (1987) Science , vol.237 , pp. 532-535
    • Daley, G.Q.1    McLaughlin, J.2    Witte, O.N.3    Baltimore, D.4
  • 13
    • 0028170213 scopus 로고
    • Structural alterations in the carboxyl-terminal domain of the BCRABL gene product activate its fibroblastic transforming potential
    • Shore, S.K., La Cava, M., Yendapalli, S. & Reddy, E.P. Structural alterations in the carboxyl-terminal domain of the BCRABL gene product activate its fibroblastic transforming potential. J. Biol. Chem. 269, 5413-5419 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 5413-5419
    • Shore, S.K.1    La Cava, M.2    Yendapalli, S.3    Reddy, E.P.4
  • 14
    • 0028881598 scopus 로고
    • The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation
    • Renshaw, M.W., McWhirter, J.R. & Wang, J.Y.J. The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation. Mol. Cell. Biol. 15, 1286-1293 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1286-1293
    • Renshaw, M.W.1    McWhirter, J.R.2    Wang, J.Y.J.3
  • 15
    • 0029015690 scopus 로고
    • Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2
    • Sanchez-Garcia, I. & Grutz, G. Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2. Proc. Natl. Acad. Sci. USA 92, 5287-5291 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5287-5291
    • Sanchez-Garcia, I.1    Grutz, G.2
  • 16
    • 0027320110 scopus 로고
    • The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells
    • Grignani, F. et al. The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells. Cell 74, 423-431 (1993).
    • (1993) Cell , vol.74 , pp. 423-431
    • Grignani, F.1
  • 17
    • 0030882823 scopus 로고    scopus 로고
    • Oncogenic transformation and inhibition of adipocytic conversion of preadipocytes by TLS/FUS-CHOP type II chimeric protein
    • Kuroda, M. et al. Oncogenic transformation and inhibition of adipocytic conversion of preadipocytes by TLS/FUS-CHOP type II chimeric protein. Am. J. Pathol. 151, 735-744 (1997).
    • (1997) Am. J. Pathol. , vol.151 , pp. 735-744
    • Kuroda, M.1
  • 18
    • 0031018906 scopus 로고    scopus 로고
    • E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts
    • Fu, X. & Kamps, M.P. E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts. Mol. Cell. Biol. 17, 1503-1512 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1503-1512
    • Fu, X.1    Kamps, M.P.2
  • 19
    • 0030931603 scopus 로고    scopus 로고
    • Cell death induction by the acute promyelocytic leukemia-specific PML/RARα fusion protein
    • Ferrucci, P.R. et al. Cell death induction by the acute promyelocytic leukemia-specific PML/RARα fusion protein. Proc. Natl. Acad. Sci. USA 94, 10901-10906 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10901-10906
    • Ferrucci, P.R.1
  • 21
    • 0026642195 scopus 로고
    • Induction of apoptosis in fibroblasts by c-myc protein
    • Evan, G.I. et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell 69, 119-128 (1992).
    • (1992) Cell , vol.69 , pp. 119-128
    • Evan, G.I.1
  • 23
    • 0028789703 scopus 로고
    • BCRIABL P210 and P190 cause distinct leukemia in transgenic mice
    • Voncken, J.W. et al. BCRIABL P210 and P190 cause distinct leukemia in transgenic mice, Blood 86, 4603-4611 (1995).
    • (1995) Blood , vol.86 , pp. 4603-4611
    • Voncken, J.W.1
  • 24
    • 0030896065 scopus 로고    scopus 로고
    • The acute promyelocytic leukemia PML-RARα protein induces hepatic preneoplastic and neoplastic lesions in transgenic mice
    • David, G., Terris, B., Marchio, A., Lavau, C. & Dejean, A. The acute promyelocytic leukemia PML-RARα protein induces hepatic preneoplastic and neoplastic lesions in transgenic mice. Oncogene 14, 1547-1554 (1997).
    • (1997) Oncogene , vol.14 , pp. 1547-1554
    • David, G.1    Terris, B.2    Marchio, A.3    Lavau, C.4    Dejean, A.5
  • 25
    • 0031033221 scopus 로고    scopus 로고
    • Altered myeloid development and acute leukemia in transgenic mice expressing PML-RARα under control of cathepsin G regulatory sequences
    • Grisolano, J.L., Wesselschmidt, R.L., Pelicci, P.G. & Ley, T.J. Altered myeloid development and acute leukemia in transgenic mice expressing PML-RARα under control of cathepsin G regulatory sequences. Blood 89, 376-387 (1997).
    • (1997) Blood , vol.89 , pp. 376-387
    • Grisolano, J.L.1    Wesselschmidt, R.L.2    Pelicci, P.G.3    Ley, T.J.4
  • 26
    • 0030615230 scopus 로고    scopus 로고
    • A PMLRARα transgene initiates murine acute promyelocytic leukemia
    • Brown, D. et al. A PMLRARα transgene initiates murine acute promyelocytic leukemia. Proc. Natl. Acad. Sci. USA 94, 2551-2556 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2551-2556
    • Brown, D.1
  • 27
    • 0029817222 scopus 로고    scopus 로고
    • Transgenic expression of PML/RARα impairs myelopoiesis
    • Early, E. et al. Transgenic expression of PML/RARα impairs myelopoiesis. Proc. Natl. Acad. Sci. USA 93, 7900-7904 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7900-7904
    • Early, E.1
  • 28
    • 0030752777 scopus 로고    scopus 로고
    • A BCR-ABLp190 fusion gene made by homologous recombination causes B-cell acute lymphoblastic leukemias in chimeric mice with independence of the endogenous bcr product
    • Castellanos, A. et al. A BCR-ABLp190 fusion gene made by homologous recombination causes B-cell acute lymphoblastic leukemias in chimeric mice with independence of the endogenous bcr product. Blood 90, 2168-2174 (1997).
    • (1997) Blood , vol.90 , pp. 2168-2174
    • Castellanos, A.1
  • 29
    • 15844394270 scopus 로고    scopus 로고
    • An MII-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes
    • Corral, J. et al. An MII-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes. Cell 85, 853-861 (1996).
    • (1996) Cell , vol.85 , pp. 853-861
    • Corral, J.1
  • 30
    • 0031025416 scopus 로고    scopus 로고
    • Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene
    • Yergeau, D.A. et al. Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene. Nature Genet. 15, 303-306 (1997).
    • (1997) Nature Genet. , vol.15 , pp. 303-306
    • Yergeau, D.A.1
  • 31
    • 16144362555 scopus 로고    scopus 로고
    • Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11
    • Castilla, L.H. et al. Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11. Cell 87, 687-696 (1996).
    • (1996) Cell , vol.87 , pp. 687-696
    • Castilla, L.H.1
  • 32
    • 0003718070 scopus 로고
    • Molecular genetics of chromosomal translocations in B- And T-lymphoid malignancies
    • (ed. Cossman, J.) Elsevier, New York
    • Haluska, F.G., Finger, L.R., Kagan, J. & Croce, C.M. Molecular genetics of chromosomal translocations in B- and T-lymphoid malignancies. in Molecular Genetics in Cancer Diagnosis (ed. Cossman, J.) 143-162 (Elsevier, New York, 1990).
    • (1990) Molecular Genetics in Cancer Diagnosis , pp. 143-162
    • Haluska, F.G.1    Finger, L.R.2    Kagan, J.3    Croce, C.M.4
  • 33
    • 0029005995 scopus 로고
    • Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation
    • Chissoe, S.L. et al. Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation. Genomics 27, 67-82 (1995).
    • (1995) Genomics , vol.27 , pp. 67-82
    • Chissoe, S.L.1
  • 34
    • 0030726781 scopus 로고    scopus 로고
    • Highly conservative reciprocal translocations formed by apparent joining of exchanged DNA double-strand break ends
    • Wang, P., Zhou, R.-H., Zou, Y., Jackson-Cook, C.K. & Povirk, L.F. Highly conservative reciprocal translocations formed by apparent joining of exchanged DNA double-strand break ends. Proc. Natl. Acad. Sci. USA 94, 12018-12023 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12018-12023
    • Wang, P.1    Zhou, R.-H.2    Zou, Y.3    Jackson-Cook, C.K.4    Povirk, L.F.5
  • 35
    • 0022976432 scopus 로고
    • Nonhomologous recombination in mammalian cells: Role for short sequence homologies in the joining reaction
    • Roth, D.B. & Wilson, J.H. Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction. Mol. Cell. Biol. 6, 4295-4304 (1986).
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 4295-4304
    • Roth, D.B.1    Wilson, J.H.2
  • 36
    • 0030012114 scopus 로고    scopus 로고
    • Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors
    • Aplan, P.D., Chervinsky, D.S., Stanulla, M. & Burhans, W.C. Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors. Blood 87, 2649-58 (1996).
    • (1996) Blood , vol.87 , pp. 2649-2658
    • Aplan, P.D.1    Chervinsky, D.S.2    Stanulla, M.3    Burhans, W.C.4


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