메뉴 건너뛰기




Volumn 151, Issue 3, 1997, Pages 735-744

Oncogenic transformation and inhibition of adipocytic conversion of preadipocytes by TLS/FUS-CHOP type II chimeric protein

Author keywords

[No Author keywords available]

Indexed keywords

ADIPSIN; CHIMERIC PROTEIN; INSULIN; THIAZOLIDINE DERIVATIVE;

EID: 0030882823     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (87)

References (53)
  • 2
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbitts TH: Chromosomal translocations in human cancer. Nature 1994, 372:143-149
    • (1994) Nature , vol.372 , pp. 143-149
    • Rabbitts, T.H.1
  • 3
    • 0027276357 scopus 로고
    • Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma
    • Rabbitts TH, Forster A, Larson R, Nathan P: Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma. Nature Genet 1993, 4:175-180
    • (1993) Nature Genet , vol.4 , pp. 175-180
    • Rabbitts, T.H.1    Forster, A.2    Larson, R.3    Nathan, P.4
  • 4
    • 0027227651 scopus 로고
    • Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma
    • Crozat A, Aman P, Mandahl N, Ron D: Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Nature 1993, 363:640-644
    • (1993) Nature , vol.363 , pp. 640-644
    • Crozat, A.1    Aman, P.2    Mandahl, N.3    Ron, D.4
  • 5
    • 0026546365 scopus 로고
    • CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
    • Ron D, Habener JF: CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev 1992, 6:439-453
    • (1992) Genes Dev , vol.6 , pp. 439-453
    • Ron, D.1    Habener, J.F.2
  • 6
    • 0028799662 scopus 로고
    • Characterization of the genomic breakpoint and chimeric transcripts in the EWS-WT1 gene fusion of desmoplastic small round cell tumor
    • Gerald WL, Rosai J, Ladanyi M: Characterization of the genomic breakpoint and chimeric transcripts in the EWS-WT1 gene fusion of desmoplastic small round cell tumor. Proc Natl Acad Sci USA 1995, 92:1028-1032
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1028-1032
    • Gerald, W.L.1    Rosai, J.2    Ladanyi, M.3
  • 10
    • 0028609788 scopus 로고
    • Characterization of the CHOP breakpoints and fusion transcripts in myxoid liposarcomas with the 12;16 translocation
    • Panagopoulos I, Mandahl N, Ron D, Hoglund M, Nilbert M, Mertens F, Mitelman F, Aman P: Characterization of the CHOP breakpoints and fusion transcripts in myxoid liposarcomas with the 12;16 translocation. Cancer Res 1994, 54:6500-6503
    • (1994) Cancer Res , vol.54 , pp. 6500-6503
    • Panagopoulos, I.1    Mandahl, N.2    Ron, D.3    Hoglund, M.4    Nilbert, M.5    Mertens, F.6    Mitelman, F.7    Aman, P.8
  • 11
    • 0028961450 scopus 로고
    • Translocation t(12;16)(q13;p11) in myxoid liposarcoma and round cell liposarcoma: Molecular and cytogenetic analysis
    • Knight JC, Renwick PJ, Cin PD, Van den Berghe H, Fletcher CD: Translocation t(12;16)(q13;p11) in myxoid liposarcoma and round cell liposarcoma: molecular and cytogenetic analysis. Cancer Res 1995, 55:24-27
    • (1995) Cancer Res , vol.55 , pp. 24-27
    • Knight, J.C.1    Renwick, P.J.2    Cin, P.D.3    Van Den Berghe, H.4    Fletcher, C.D.5
  • 13
    • 0028168540 scopus 로고
    • Transcriptional activation by TAL1 and FUS-CHOP proteins expressed in acute malignancies as a result of chromosomal abnormalities
    • Sanchez GI, Rabbitts TH: Transcriptional activation by TAL1 and FUS-CHOP proteins expressed in acute malignancies as a result of chromosomal abnormalities. Proc Natl Acad Sci USA 1994, 91:7869-7873
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7869-7873
    • Sanchez, G.I.1    Rabbitts, T.H.2
  • 14
    • 0027970712 scopus 로고
    • A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP
    • Zinszner H, Albalat R, Ron D: A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP. Genes Dev 1994, 8:2513-2526
    • (1994) Genes Dev , vol.8 , pp. 2513-2526
    • Zinszner, H.1    Albalat, R.2    Ron, D.3
  • 15
    • 0025853968 scopus 로고
    • Cell culture models of differentiation
    • Watt FM: Cell culture models of differentiation. FASEB J 1991, 5:287-294
    • (1991) FASEB J , vol.5 , pp. 287-294
    • Watt, F.M.1
  • 16
    • 0018581647 scopus 로고
    • Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine
    • Taylor SM, Jones PA: Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 1979, 17:771-779
    • (1979) Cell , vol.17 , pp. 771-779
    • Taylor, S.M.1    Jones, P.A.2
  • 18
    • 0020058116 scopus 로고
    • Pre-adipocyte determination either by insulin or by 5-azacytidine
    • Sager R, Kovac P: Pre-adipocyte determination either by insulin or by 5-azacytidine. Proc Natl Acad Sci USA 1982, 79:480-484
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 480-484
    • Sager, R.1    Kovac, P.2
  • 21
    • 0026048640 scopus 로고
    • The CCAAT/enhancer binding protein and its role in adipocyte differentiation: Evidence for direct involvement in terminal adipocyte development
    • Samuelsson L, Stromberg K, Vikman K, Bjursell G, Enerback S: The CCAAT/enhancer binding protein and its role in adipocyte differentiation: evidence for direct involvement in terminal adipocyte development. EMBO J 1991, 10:3787-3793
    • (1991) EMBO J , vol.10 , pp. 3787-3793
    • Samuelsson, L.1    Stromberg, K.2    Vikman, K.3    Bjursell, G.4    Enerback, S.5
  • 22
    • 0026031601 scopus 로고
    • CCAAT-enhancer binding protein: A component of a differentiation switch
    • Umek RM, Friedman AD, McKnight SL: CCAAT-enhancer binding protein: a component of a differentiation switch. Science 1991, 251: 288-292
    • (1991) Science , vol.251 , pp. 288-292
    • Umek, R.M.1    Friedman, A.D.2    McKnight, S.L.3
  • 23
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • Tontonoz P, Hu E, Spiegelman BM: Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 1994, 79:1147-1156
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 24
    • 0027420920 scopus 로고
    • A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: Transcriptional activator lacking antimitotic activity
    • Lin FT, MacDougald OA, Diehl AM, Lane MD: A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity. Proc Natl Acad Sci USA 1993, 90:9606-9610
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9606-9610
    • Lin, F.T.1    MacDougald, O.A.2    Diehl, A.M.3    Lane, M.D.4
  • 25
    • 0028129499 scopus 로고
    • Ectopic expression of the CCAAT/ enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells
    • Freytag SO, Paielli DL, Gilbert JD: Ectopic expression of the CCAAT/ enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev 1994, 8:1654-1663
    • (1994) Genes Dev , vol.8 , pp. 1654-1663
    • Freytag, S.O.1    Paielli, D.L.2    Gilbert, J.D.3
  • 26
    • 0028564903 scopus 로고
    • CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program
    • Lin FT, Lane MD: CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program. Proc Natl Acad Sci USA 1994, 91:8757-8761
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8757-8761
    • Lin, F.T.1    Lane, M.D.2
  • 27
    • 0029130373 scopus 로고
    • Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153)
    • Batchvarova N, Wang XZ, Ron D: Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153). EMBO J 1995, 14:4654-4661
    • (1995) EMBO J , vol.14 , pp. 4654-4661
    • Batchvarova, N.1    Wang, X.Z.2    Ron, D.3
  • 28
    • 0019187246 scopus 로고
    • Establishment of a clonal cell line that differentiates into adipose cells in vitro
    • Hiragun A, Sato M, Mitsui H: Establishment of a clonal cell line that differentiates into adipose cells in vitro. In Vitro 1980, 16:685-693
    • (1980) In Vitro , vol.16 , pp. 685-693
    • Hiragun, A.1    Sato, M.2    Mitsui, H.3
  • 29
    • 0016693548 scopus 로고
    • An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion
    • Green H, Kehinde O: An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 1975, 5:19-27
    • (1975) Cell , vol.5 , pp. 19-27
    • Green, H.1    Kehinde, O.2
  • 30
    • 0344070478 scopus 로고
    • Establishment of preadipocyte clonal line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones
    • Negrel R, Grimaldi P, Ailhaud G: Establishment of preadipocyte clonal line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones. Proc Natl Acad Sci USA 1978, 75:6054-6058
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 6054-6058
    • Negrel, R.1    Grimaldi, P.2    Ailhaud, G.3
  • 31
    • 0023850852 scopus 로고
    • Preadipocyte differentiation in vitro: Identification of a highly active adipogenic agent
    • Hiragun A, Sato M, Mitsui H: Preadipocyte differentiation in vitro: identification of a highly active adipogenic agent. J Cell Physiol 1988, 134:124-130
    • (1988) J Cell Physiol , vol.134 , pp. 124-130
    • Hiragun, A.1    Sato, M.2    Mitsui, H.3
  • 32
    • 0026028217 scopus 로고
    • Antidiabetic AD4743 enhances adipocyte differentiation of 3T3 T mesenchymal stem cells
    • Sparks RL, Strauss EE, Zygmunt AI, Phelan TE: Antidiabetic AD4743 enhances adipocyte differentiation of 3T3 T mesenchymal stem cells. J Cell Physiol 1991, 146:101-109
    • (1991) J Cell Physiol , vol.146 , pp. 101-109
    • Sparks, R.L.1    Strauss, E.E.2    Zygmunt, A.I.3    Phelan, T.E.4
  • 33
    • 0026517080 scopus 로고
    • Enhancement of adipocyte differentiation by an insulin-sensitizing agent
    • Kletzien RF, Clarke SD, Ulrich RG: Enhancement of adipocyte differentiation by an insulin-sensitizing agent. Mol Pharmacol 1992, 41: 393-398
    • (1992) Mol Pharmacol , vol.41 , pp. 393-398
    • Kletzien, R.F.1    Clarke, S.D.2    Ulrich, R.G.3
  • 34
    • 0027256247 scopus 로고
    • Antidiabetic agent pioglitazone enhances adipocyte differentiation of 3T3-F442A cells
    • Sandouk T, Reda D, Hofmann C: Antidiabetic agent pioglitazone enhances adipocyte differentiation of 3T3-F442A cells. Am J Physiol 1993, 264:C1600-C1608
    • (1993) Am J Physiol , vol.264
    • Sandouk, T.1    Reda, D.2    Hofmann, C.3
  • 35
    • 0021280902 scopus 로고
    • Studies on antidiabetic agents. IV. Synthesis and activity of the metabolites of 5-[4-(1-methylcyclohexylmethoxy)benzyl]-2,4-thiazolidinedione (ciglitazone)
    • Sohda T, Meguro K, Kawamatsu Y: Studies on antidiabetic agents. IV. Synthesis and activity of the metabolites of 5-[4-(1-methylcyclohexylmethoxy)benzyl]-2,4-thiazolidinedione (ciglitazone). Chem Pharm Bull 1984, 32:2267-2278
    • (1984) Chem Pharm Bull , vol.32 , pp. 2267-2278
    • Sohda, T.1    Meguro, K.2    Kawamatsu, Y.3
  • 37
    • 0028787395 scopus 로고
    • Constitutive overexpression of the L-selectin gene in fresh leukemic cells of adult T-cell leukemia that can be transactivated by human T-cell lymphotropic virus type I Tax
    • Tatewaki M, Yamaguchi K, Matsuoka M, Ishii T, Miyasaka M, Mori S, Takatsuki K, Watanabe T: Constitutive overexpression of the L-selectin gene in fresh leukemic cells of adult T-cell leukemia that can be transactivated by human T-cell lymphotropic virus type I Tax. Blood 1995, 86:3109-3117
    • (1995) Blood , vol.86 , pp. 3109-3117
    • Tatewaki, M.1    Yamaguchi, K.2    Matsuoka, M.3    Ishii, T.4    Miyasaka, M.5    Mori, S.6    Takatsuki, K.7    Watanabe, T.8
  • 39
    • 0028889290 scopus 로고
    • Molecular cloning, sequence, and expression patterns of the human gene encoding CCAAT/enhancer binding protein alpha (C/EBP alpha)
    • Antonson P, Xanthopoulos KG: Molecular cloning, sequence, and expression patterns of the human gene encoding CCAAT/enhancer binding protein alpha (C/EBP alpha). Biochem Biophys Res Commun 1995, 215:106-113
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 106-113
    • Antonson, P.1    Xanthopoulos, K.G.2
  • 40
    • 0027950397 scopus 로고
    • An improved fluor diffusion assay for chloramphenicol acetyltransferase gene expression
    • Purschke WG, Muller PK: An improved fluor diffusion assay for chloramphenicol acetyltransferase gene expression. Biotechniques 1994, 16:264-265
    • (1994) Biotechniques , vol.16 , pp. 264-265
    • Purschke, W.G.1    Muller, P.K.2
  • 41
    • 0021749262 scopus 로고
    • Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma
    • Herbomel P, Bourachot B, Yaniv M: Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma. Cell 1984, 39:653-662
    • (1984) Cell , vol.39 , pp. 653-662
    • Herbomel, P.1    Bourachot, B.2    Yaniv, M.3
  • 42
    • 0024728988 scopus 로고
    • Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes
    • Christy RJ, Yang VW, Ntambi JM, Geiman DE, Landschulz WH, Friedman AD, Nakabeppu Y, Kelly TJ, Lane MD: Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes. Genes Dev 1989, 3:1323-1335
    • (1989) Genes Dev , vol.3 , pp. 1323-1335
    • Christy, R.J.1    Yang, V.W.2    Ntambi, J.M.3    Geiman, D.E.4    Landschulz, W.H.5    Friedman, A.D.6    Nakabeppu, Y.7    Kelly, T.J.8    Lane, M.D.9
  • 43
    • 0024398546 scopus 로고
    • A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation
    • Herrera R, Ro HS, Robinson GS, Xanthopoulos KG, Spiegelman BM: A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation. Mol Cell Biol 1989, 9:5331-5339
    • (1989) Mol Cell Biol , vol.9 , pp. 5331-5339
    • Herrera, R.1    Ro, H.S.2    Robinson, G.S.3    Xanthopoulos, K.G.4    Spiegelman, B.M.5
  • 44
    • 0026050219 scopus 로고
    • Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
    • Cao Z, Umek RM, McKnight SL: Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev 1991, 5:1538-1552
    • (1991) Genes Dev , vol.5 , pp. 1538-1552
    • Cao, Z.1    Umek, R.M.2    McKnight, S.L.3
  • 45
    • 1842279106 scopus 로고
    • Expression of specific mRNAs during adipose differentiation: Identification of an mRNA encoding a homologue of myelin P2 protein
    • Bernlohr DA, Angus CW, Lane MD, Bolanowski MA, Kelly TJ Jr: Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc Natl Acad Sci USA 1984, 81:5468-5472
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5468-5472
    • Bernlohr, D.A.1    Angus, C.W.2    Lane, M.D.3    Bolanowski, M.A.4    Kelly Jr., T.J.5
  • 46
    • 0022001096 scopus 로고
    • Developmentally regulated mRNAs in 3T3-adipocytes: Analysis of transcriptional control
    • Cook KS, Hunt CR, Spiegelman BM: Developmentally regulated mRNAs in 3T3-adipocytes: analysis of transcriptional control. J Cell Biol 1985, 100:514-520
    • (1985) J Cell Biol , vol.100 , pp. 514-520
    • Cook, K.S.1    Hunt, C.R.2    Spiegelman, B.M.3
  • 47
    • 0010626731 scopus 로고
    • Adipocyte P2 gene: Developmental expression and homology of 5′-flanking sequences among fat cell-specific genes
    • Hunt CR, Ro JH, Dobson DE, Min HY, Spiegelman BM: Adipocyte P2 gene: developmental expression and homology of 5′-flanking sequences among fat cell-specific genes. Proc Natl Acad Sci USA 1986, 83:3786-3790
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 3786-3790
    • Hunt, C.R.1    Ro, J.H.2    Dobson, D.E.3    Min, H.Y.4    Spiegelman, B.M.5
  • 48
    • 0023057194 scopus 로고
    • Adipsin, the adipocyte serine protease: Gene structure and control of expression by tumor necrosis factor
    • Min HY, Spiegelman BM: Adipsin, the adipocyte serine protease: gene structure and control of expression by tumor necrosis factor. Nucleic Acids Res 1986, 14:8879-8892
    • (1986) Nucleic Acids Res , vol.14 , pp. 8879-8892
    • Min, H.Y.1    Spiegelman, B.M.2
  • 49
    • 0026511284 scopus 로고
    • Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes
    • Lin FT, Lane MD: Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes. Genes Dev 1992, 6:533-544
    • (1992) Genes Dev , vol.6 , pp. 533-544
    • Lin, F.T.1    Lane, M.D.2
  • 50
    • 23444443039 scopus 로고
    • CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest
    • Barone MV, Crozat A, Tabaee A, Philipson L, Ron D: CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev 1992, 8:453-464
    • (1992) Genes Dev , vol.8 , pp. 453-464
    • Barone, M.V.1    Crozat, A.2    Tabaee, A.3    Philipson, L.4    Ron, D.5
  • 51
    • 0026586526 scopus 로고
    • Reciprocal regulation of adipogenesis by Myc and C/EBPα
    • Freytag SO, Geddes TJ: Reciprocal regulation of adipogenesis by Myc and C/EBPα. Science 1992, 256:379-382
    • (1992) Science , vol.256 , pp. 379-382
    • Freytag, S.O.1    Geddes, T.J.2
  • 52
    • 0028129498 scopus 로고
    • Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts
    • Pegano M, Theodoras AM, Tam SW, Draetta GF: Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes Dev 1994, 8:1627-1639
    • (1994) Genes Dev , vol.8 , pp. 1627-1639
    • Pegano, M.1    Theodoras, A.M.2    Tam, S.W.3    Draetta, G.F.4
  • 53
    • 0027948152 scopus 로고
    • TLS/FUS fusion domain of TLS/FUS-erg chimeric protein resulting from the t(16;21) chromosomal translocation in human myeloid leukemia functions as a transcriptional activation domain
    • Prasad DDK, Ouchida M, Lee L, Rao VN, Reddy SP: TLS/FUS fusion domain of TLS/FUS-erg chimeric protein resulting from the t(16;21) chromosomal translocation in human myeloid leukemia functions as a transcriptional activation domain. Oncogene 1994, 9:3717-3729
    • (1994) Oncogene , vol.9 , pp. 3717-3729
    • Prasad, D.D.K.1    Ouchida, M.2    Lee, L.3    Rao, V.N.4    Reddy, S.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.