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Volumn 10, Issue 3, 1998, Pages 322-329

GTPases in antigen receptor signalling

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; GUANOSINE TRIPHOSPHATASE; LYMPHOCYTE ANTIGEN RECEPTOR; RHO FACTOR;

EID: 0031834601     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(98)80171-4     Document Type: Article
Times cited : (65)

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    • Vossler MR, Yao H, York RD, Pan M-G, Rim CS, Stork PJS. cAMP activates MAP kinase and Elk-1 through a B-raf- and rap1-dependent pathway. of special interest Cell. 89:1997;73-82 This report suggests that Rap1 may also have positive signalling effects. In PC12 cells cAMP is able to induce neuronal differentiation and activation of the Elk-1 transcription factor via the activation of the mitogen-activated protein kinase cascade which is dependent on the expression of B-Raf and Rap1. In B-Raf expressing cells Rap1 can therefore be envisioned as a selective activator of B-Raf and an inhibitor of Raf-1.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.