Regulation of bHLH-PAS protein subcellular localization during Drosophila embryogenesis

Development

Volumn 125, Issue 9, 1998, Pages 1599-1608

  Ward, Mary P ^a   Mosher, Jack T ^a   Crews, Stephen T ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Arnt; bHLH PAS; Nuclear localization; Single minded (Sim); Tango (Tgo); Trachealess (Trh)

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYTOPLASM PROTEIN; HELIX LOOP HELIX PROTEIN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM; CYTOPLASM; DROSOPHILA; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; MESODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SALIVARY GLAND DUCT; TRACHEA;

ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARRIER PROTEINS; CELL NUCLEUS; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CYTOPLASM; DIMERIZATION; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; ECTODERM; EMBRYO, NONMAMMALIAN; HELIX-LOOP-HELIX MOTIFS; MESODERM; NUCLEAR PROTEINS; ORGAN SPECIFICITY; SALIVARY DUCTS; TRACHEA; TRANSCRIPTION FACTORS;

ANIMALIA; MAMMALIA;

EID: 0031834240     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Abbott, B. D., Birnbaum, L. S. and Perdew, G. H. (1995). Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo. Dev. Dyn. 204, 133-143.
2. Abbott, B. D. and Probst, M. R. (1995). Developmental expression of two members of a new class of transcription factors: II. Expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6N mouse embryo. Dev. Dyn. 204, 144-155.
3. Antonsson, C., Arulampalam, V., Whitelaw, M. L., Petterson, S. and Poellinger, L. (1995). Constitutive function of the basic helix-loop-helix/PAS factor Arnt. Regulation of target promoters via the E box motif. J. Biol. Chem. 270, 13968-13972.
4. Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
5. Burbach, K. M., Poland, A. and Bradfield, C. A. (1992). Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc. Nat. Acad. Sci. USA 89, 8185-8189.
6. Campos-Ortega, J. A. and Hartenstein, V. (1985). The Embryonic Development of Drosophila melanogaster. Berlin, Heidelberg: Springer Verlag.
7. Chen, H., Chrast, R., Rossier, C., Gos, A., Antonarakis, S. E., Kudoh, J., Yamaki, A., Shindoh, N., Maeda, H., Minoshima, S. and Shimizu, N. (1995). Single-minded and Down syndrome. Nature Genet. 10, 9-10.
8. Crews, S. T. (1998). Control of cell lineage-specific development and transcription by bHLH-PAS proteins. Genes Dev. (in press).
9. Crews, S. T., Thomas, J. B. and Goodman, C. S. (1988). The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product. Cell 52, 143-151.
10. Dahmane, N., Charron, G., Lopes, C., Yaspo, M. L., Maunoury, C., Decorte, L., Sinet, P. M., Bloch, B. and Delabar, J. M. (1995). Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development. Proc. Natl. Acad. Sci. USA 92, 9191-9195.
11. Denis, M., Cuthill, S., Wikstrom, A. C., Poellinger, L. and Gustafsson, J.-A. (1988). Association of the dioxin receptor with the Mr 90,000 heat shock protein: a structural kinship with the glucocorticoid receptor. Biochem. Biophys. Res. Comm. 155, 801-807.
12. Edwards, D. N., Towb, P. and Wasserman, S. A. (1997). An activity- dependent network of interactions links the Re1 protein Dorsal with its cytoplasmic regulators. Development 124, 3855-3864.
13. Eguchi, H., Ikuta, T., Tachibana, T., Yoneda, Y. and Kawajiri, K. (1997). A nuclear localization signal of human aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor 1β is a novel bipartite type recognized by the two components of nuclear pore-targeting complex. J. Biol. Chem. 272, 17640-17647.
14. Ema, M., Morita, M., Ikawa, S., Tanaka, M., Matsuda, Y., Gotoh, O., Saijoh, Y., Fujii, H., Hamada, H. and Fujii-Kuriyama, Y. (1997). Two new members of murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis. Mol. Cell. Biol. 16, 5865-5875.
15. Ema, M., Sogawa, K., Watanabe, N., Chujoh, Y., Matsushita, N., Gotoh, O., Funae, Y. and Fujii-Kuriyama, Y. (1992). cDNA cloning and structure of mouse putative Ah receptor. Biochem. Biophys. Res. Comm. 184, 246- 253.
16. Fan, C.-M., Kuwana, E., Bulfone, A., Fletcher, C. F., Copeland, N. G., Jenkins, N. A., Crews, S., Martinez, S., Puelles, L., Rubenstein, J. L. R. and Tessier-Lavigne, M. (1996). Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down Syndrome. Mol. Cell. Neuro. 7, 1-16.
17. Foe, V. E. (1989). Mitotic domains reveal early commitment of cells in Drosophila embryos. Development 107, 1-22.
18. Hoffman, E. C., Reyes, H., Chu, F., Sander, F., Conley, L. H., Brooks, B. A. and Hankinson, O. (1991). Cloning of a subunit of the DNA-binding form of the Ah (dioxin) receptor. Science 252, 954-958.
19. Isaac, D. D. and Andrew, D. J. (1996). Tubulogenesis in Drosophila: a requirement for the trachealess gene product. Genes Dev. 10, 103-117.
20. Ma, Q. and Whitlock, J. J. P. (1997). A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2, 3, 7, 8-tetrachlorodibenzo-p- dioxin. J. Biol. Chem. 272, 8878-8884.
21. Nambu, J. R., Chen, W., Hu, S. and Crews, S. T. (1996). The Drosophila melanogaster similar bHLH-PAS gene encodes a protein related to human Hypoxia-inducible factor 1α and Drosophila Single-minded. Gene 172, 249-254.
22. Nambu, J. R., Franks, R. G., Hu, S. and Crews, S. T. (1990). The single- minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells. Cell 63, 63-75.
23. Nambu, J. R., Lewis, J. L., Wharton, K. A. and Crews, S. T. (1991). The Drosophila single-minded gene encodes a helix-loop-helix protein which acts as a master regulator of CNS midline development. Cell 67, 1157-1167.
24. Ohshiro, T. and Saigo, K. (1997). Transcriptional regulation of breathless FGF receptor gene by binding of TRACHEALESS/dARNT heterodimers to three central midline elements in Drosophila developing trachea. Development 124, 3975-3986.
25. Orsulic, S. and Peifer, M. (1996). Cell-cell signalling: Wingless lands at last. Curr. Biol. 6, 1363-1367.
26. Patel, N. H., Snow, P. M. and Goodman, C. S. (1987). Characterization and cloning of fasciclin III: a glycoprotein expressed on a subset of neurons and axon pathways in Drosophila. Cell 48, 975-988.
27. Perdew, G. H. (1988). Association of the Ah receptor with the 90-kDa heat shock protein. J. Biol. Chem. 263, 13802-13805.
28. Pollenz, R. S., Sattler, C. A. and Poland, A. (1994). The aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator protein show distinct subcellular localizations in Hepa 1c1c7 cells by immunofluorescence microscopy. Mol. Pharmacol. 45, 428-438.
29. Probst, M. R., Fan, C.-M., Tessier-Lavigne, M. and Hankinson, O. (1997). Two murine homologs of the Drosophila Single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein. J. Biol. Chem. 272, 4451-4457.
30. Roth, S., Stein, D. and Nusslein-Volhard, C. (1989). A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo. Cell 59, 1189-1202.
31. Rowlands, J. C. and Gustafsson, J.-A. (1997). Aryl hydrocarbon receptor- mediated signal transduction. Crit. Rev. Toxicol. 27, 109-134.
32. Rupp, R. A., Snider, L. and Weintraub, H. (1994). Xenopus embryos regulate the nuclear localization of XMyoD. Genes Dev. 8, 1311-1323.
33. Rusch, J. and Levine, M. (1996). Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo. Curr. Opin. Genet. Dev. 6, 416-423.
34. Rushlow, C., Han, K., Manley, J. L. and Levine, M. (1989). The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila. Cell 59, 1165-1177.
35. Sogawa, K. R., Nakano, A., Kobayashi, Y., Kikuchi, N., Ohe, N., Matsushita, N. and Fujii-Kuriyama, Y. (1995). Possible function of Ah receptor nuclear translocator (Arnt) homodimer in transcriptional regulation. Proc. Nat. Acad. Sci USA 92, 1936-1940.
36. Sonnenfeld, M., Ward, M., Nystrom, G., Mosher, J., Stahl, S. and Crews, S. (1997). The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development. Development 124, 4583-4594.
37. Steward, R. (1989). Relocalization of the dorsal protein from the cytoplasm correlates with its function. Cell 59, 1179-1188.
38. Swanson, H. I., Chan, W. K. and Bradfield, C. A. (1995). DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins. J. Biol. Chem. 280, 26292-26302.
39. Thomas, J. B., Crews, S. T. and Goodman, C. S. (1988). Molecular genetics of the single-minded locus: a gene involved in the development of the Drosophila nervous system. Cell 52, 133-141.
40. Vandromme, M., Gauthier-Rouviere, C., Lamb, N. and Fernandez, A. (1996). Regulation of transcription factor localization: fine-tuning of gene expression. Trends Biochem. Sci. 21, 59-64.
41. 2 tension. Proc. Natl. Acad. Sci. USA 92, 5510-5514.
42. Wharton, Jr., K. A., Franks, R. G., Kasai, Y. and Crews, S. T. (1994). Control of CNS midline transcription by asymmetric E-box elements: similarity to xenobiotic responsive regulation. Development 120, 3563-3569.
43. Wiener, C. M., Booth, G. and Semenza, G. L. (1996). In vivo expression of mRNAs encoding hypoxia-inducible factor 1. Biochem. Biophys. Res. Comm. 225, 485-488.
44. Wilk, R., Weizman, I., Glazer, L. and Shilo, B.-Z. (1996). trachealess encodes a bHLH-PAS protein and is a master regulator gene in the Drosophila tracheal system. Genes Dev. 10, 93-102.
45. Williams, J. A., Langeland, J. A., Thalley, B. S., Skeath, J. B. and Carroll, S. B. (1995). Expression of foreign proteins in E. coli using plasmid vectors and purification of specific polyclonal antibodies. In DNA Cloning 2: A Practical Approach (ed. D. M. Glover and B. D. Hames), pp. 15-58. IRL Press, Oxford.
46. Zelzer, E., Wappner, P. and Shilo, B.-Z. (1997). The PAS domain confers target gene specificity of Drosophila bHLH/PAS proteins. Genes Dev. 11, 2079-2089.