Potential and limitations of a γ34.5 mutant of herpes simplex 1 as a gene therapy vector in the CNS

Gene Therapy

Volumn 5, Issue 5, 1998, Pages 594-604

  McMenamin, M M ^a   Byrnes, A P ^a   Pike, F G ^a   Charlton, H M ^a   Coffin, R S ^b   Latchman, D S ^b   Wood, M J A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

HSV; Neurovirulent; Reporter gene; Retrograde transport; Striatum

Indexed keywords

BETA GALACTOSIDASE; DNA; DNA BINDING PROTEIN; VIRUS ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; EXPRESSION VECTOR; GENE EXPRESSION; GENE THERAPY; HERPES SIMPLEX VIRUS 1; IMMUNOHISTOCHEMISTRY; MARKER GENE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; TRANSGENE; VIRUS MUTANT;

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1;

EID: 0031832809     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300639     Document Type: Article

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