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Volumn 47, Issue 7, 1998, Pages 277-284

Macrophage NRAMP1 and its role in resistance to microbial infections

Author keywords

Divalent cations transport; Infectious diseases; Intracellular parasites; Mononuclear phagocytes

Indexed keywords

CELL PROTEIN; MEMBRANE PROTEIN; TRANSFERRIN;

EID: 0031820381     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110050330     Document Type: Review
Times cited : (144)

References (65)
  • 1
    • 0001752786 scopus 로고    scopus 로고
    • White House to expand response to infectious diseases
    • Young P. White House to expand response to infectious diseases. American Society for Microbiology News 1996; 62:450-1.
    • (1996) American Society for Microbiology News , vol.62 , pp. 450-451
    • Young, P.1
  • 3
    • 23444440823 scopus 로고
    • Inactivation of antibiotics and the dissemination of resistance genes
    • Davies J. Inactivation of antibiotics and the dissemination of resistance genes. Science 1994;264:375-82.
    • (1994) Science , vol.264 , pp. 375-382
    • Davies, J.1
  • 4
    • 0026760182 scopus 로고
    • The crisis in antibiotics resistance
    • Neu HC. The crisis in antibiotics resistance. Science 1992;257:1064-72.
    • (1992) Science , vol.257 , pp. 1064-1072
    • Neu, H.C.1
  • 5
    • 0028932451 scopus 로고
    • The changing face of tuberculosis
    • Huebner RE, Castro KG. The changing face of tuberculosis. Annu Rev Med 1995;46: 47-55.
    • (1995) Annu Rev Med , vol.46 , pp. 47-55
    • Huebner, R.E.1    Castro, K.G.2
  • 6
    • 0028879494 scopus 로고
    • Prospects for new interventions in the treatment and prevention of Mycobacterial disease
    • Young DB, Duncan K. Prospects for new interventions in the treatment and prevention of Mycobacterial disease. Annu Rev Microbiol 1995;49:641-73.
    • (1995) Annu Rev Microbiol , vol.49 , pp. 641-673
    • Young, D.B.1    Duncan, K.2
  • 7
    • 0027065581 scopus 로고
    • Genetics and resistance to tuberculosis. Could resistance be enhanced by genetic engineering?
    • Stead WW. Genetics and resistance to tuberculosis. Could resistance be enhanced by genetic engineering? Ann Int Med 1992;116:937-41.
    • (1992) Ann Int Med , vol.116 , pp. 937-941
    • Stead, W.W.1
  • 9
    • 0029151618 scopus 로고
    • Immunogenetics in the analysis of resistance to intracellular pathogens
    • McLeod R, Buschman E, Arbuckle LD, Skamene E. Immunogenetics in the analysis of resistance to intracellular pathogens. Curr Opin Immunol 1995;7:539-52.
    • (1995) Curr Opin Immunol , vol.7 , pp. 539-552
    • McLeod, R.1    Buschman, E.2    Arbuckle, L.D.3    Skamene, E.4
  • 11
    • 0028059622 scopus 로고
    • Genetic control of resistance to infection
    • Malo D, Skamene E. Genetic control of resistance to infection. Trends Genet 1994;10:365-71.
    • (1994) Trends Genet , vol.10 , pp. 365-371
    • Malo, D.1    Skamene, E.2
  • 12
    • 0019436090 scopus 로고
    • Differences in response among inbred strains of mice to infection with small doses of Mycobacterium bovis (BCG)
    • Forget A, Skamene E, Gros P, Miailhe AC, Turcotte R. Differences in response among inbred strains of mice to infection with small doses of Mycobacterium bovis (BCG). Infect Immun 1981;32:42-47.
    • (1981) Infect Immun , vol.32 , pp. 42-47
    • Forget, A.1    Skamene, E.2    Gros, P.3    Miailhe, A.C.4    Turcotte, R.5
  • 13
    • 0019835032 scopus 로고
    • Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice
    • Gros P, Skamene E, Forget A. Genetic control of natural resistance to Mycobacterium bovis (BCG) in mice. J Immunol 1981; 127:2417-23.
    • (1981) J Immunol , vol.127 , pp. 2417-2423
    • Gros, P.1    Skamene, E.2    Forget, A.3
  • 15
    • 0021080456 scopus 로고
    • Genetic control of the innate resistance of mice to Salmonella typhimurium: Expression of the Ity gene in peritoneal and splenic macrophages isolated in vitro
    • Lissner CR, Swanson RN, O'Brien AD. Genetic control of the innate resistance of mice to Salmonella typhimurium: Expression of the Ity gene in peritoneal and splenic macrophages isolated in vitro. J Immunol 1983;131:3006-13.
    • (1983) J Immunol , vol.131 , pp. 3006-3013
    • Lissner, C.R.1    Swanson, R.N.2    O'Brien, A.D.3
  • 16
    • 0021288683 scopus 로고
    • Expression of the natural resistance gene Lsh in resident liver macrophages
    • Crocker PR, Blackwell JM, Bradley DJ. Expression of the natural resistance gene Lsh in resident liver macrophages. Infect Immun 1984;43:1033-40.
    • (1984) Infect Immun , vol.43 , pp. 1033-1040
    • Crocker, P.R.1    Blackwell, J.M.2    Bradley, D.J.3
  • 17
    • 0020512901 scopus 로고
    • Cellular mechanism of genetically controlled host resistance to Mycobacterium bovis (BCG)
    • Gros P, Skamene E, Forget A. Cellular mechanism of genetically controlled host resistance to Mycobacterium bovis (BCG). J Immunol 1983;131:1966-72.
    • (1983) J Immunol , vol.131 , pp. 1966-1972
    • Gros, P.1    Skamene, E.2    Forget, A.3
  • 18
    • 0021348232 scopus 로고
    • Phenotypic expression of genetically controlled natural resistance to Mycobacterium bovis (BCG)
    • Stach JL, Gros P, Forget A, Skamene E. Phenotypic expression of genetically controlled natural resistance to Mycobacterium bovis (BCG). J Immunol 1984;132:888-92.
    • (1984) J Immunol , vol.132 , pp. 888-892
    • Stach, J.L.1    Gros, P.2    Forget, A.3    Skamene, E.4
  • 19
    • 0023008802 scopus 로고
    • Role of mononuclear phagocytes in expression of resistance and susceptibility to Mycobacterium avium infections in mice
    • Stokes RW, Orme I, Collins FM. Role of mononuclear phagocytes in expression of resistance and susceptibility to Mycobacterium avium infections in mice. Infect Immun 1986; 54:811-9.
    • (1986) Infect Immun , vol.54 , pp. 811-819
    • Stokes, R.W.1    Orme, I.2    Collins, F.M.3
  • 20
    • 0027317323 scopus 로고
    • Implication of phagosome-lysosome fusion in restriction of Mycobacterium avium growth in bone marrow macrophages from genetically resistant mice
    • de Chastellier C, Frehel C, Offredo C, Skamene E. Implication of phagosome-lysosome fusion in restriction of Mycobacterium avium growth in bone marrow macrophages from genetically resistant mice. Infect Immun 1993;61:3775-84.
    • (1993) Infect Immun , vol.61 , pp. 3775-3784
    • De Chastellier, C.1    Frehel, C.2    Offredo, C.3    Skamene, E.4
  • 21
    • 0025034754 scopus 로고
    • Killing of Mycobacterium smegmatis by macrophages from genetically susceptible and resistant mice
    • Denis M, Forget A, Pelletier M, Gervais F, Skamene E. Killing of Mycobacterium smegmatis by macrophages from genetically susceptible and resistant mice. J Leukoc Biol 1990;47:25-30.
    • (1990) J Leukoc Biol , vol.47 , pp. 25-30
    • Denis, M.1    Forget, A.2    Pelletier, M.3    Gervais, F.4    Skamene, E.5
  • 22
    • 0027211744 scopus 로고
    • High-resolution linkage map in the vicinity of the host resistance locus Bcg on mouse chromosome 1
    • Malo D, Vidal SM, Skamene E, Gros P. High-resolution linkage map in the vicinity of the host resistance locus Bcg on mouse chromosome 1. Genomics 1993;16:655-63.
    • (1993) Genomics , vol.16 , pp. 655-663
    • Malo, D.1    Vidal, S.M.2    Skamene, E.3    Gros, P.4
  • 23
    • 0027262167 scopus 로고
    • Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg
    • Vidal SM, Malo D, Vogan K, Skamene E, Gros P. Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg. Cell 1993;73:469-85.
    • (1993) Cell , vol.73 , pp. 469-485
    • Vidal, S.M.1    Malo, D.2    Vogan, K.3    Skamene, E.4    Gros, P.5
  • 24
    • 0028174663 scopus 로고
    • NH2 terminal sequence of macrophage-expressed natural resistance associated macrophage protein (Nramp) encodes a proline/serine-rich putative Src homology 3-binding domain
    • Barton CH, White JK, Roach TIA, Blackwell JM. NH2 terminal sequence of macrophage-expressed natural resistance associated macrophage protein (Nramp) encodes a proline/serine-rich putative Src homology 3-binding domain. J Exp Med 1994;179: 1683-7.
    • (1994) J Exp Med , vol.179 , pp. 1683-1687
    • Barton, C.H.1    White, J.K.2    Roach, T.I.A.3    Blackwell, J.M.4
  • 25
    • 0026786329 scopus 로고
    • Topology of the hydrophobic membrane-bound components of the histidine periplasmic permease. Comparison with other members of the family
    • Kerppola RE, Ames GFL. Topology of the hydrophobic membrane-bound components of the histidine periplasmic permease. Comparison with other members of the family. J Biol Chem 1992;267:2329-36.
    • (1992) J Biol Chem , vol.267 , pp. 2329-2336
    • Kerppola, R.E.1    Ames, G.F.L.2
  • 26
    • 0029978520 scopus 로고    scopus 로고
    • Resistance to intracellular infections: Comparative genome of NRAMP
    • Cellier M, Belouchi A, Gros P. Resistance to intracellular infections: Comparative genome of NRAMP. Trends Genet 1996;12:201-4.
    • (1996) Trends Genet , vol.12 , pp. 201-204
    • Cellier, M.1    Belouchi, A.2    Gros, P.3
  • 27
    • 0027934322 scopus 로고
    • Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites
    • Malo D, Vogan K, Vidal SM, Hu J, Cellier M, Schurr E, et al. Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites. Genomics 1994;23:51-61.
    • (1994) Genomics , vol.23 , pp. 51-61
    • Malo, D.1    Vogan, K.2    Vidal, S.M.3    Hu, J.4    Cellier, M.5    Schurr, E.6
  • 28
    • 0029092312 scopus 로고
    • The Ity/Lsh/Bcg locus: Natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp 1 gene
    • Vidal SM, Tremblay ML, Govoni G, Gauthier S, Sebastiani G, Malo D, et al. The Ity/Lsh/Bcg locus: Natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp 1 gene. J Exp Med 1995;182:655-66.
    • (1995) J Exp Med , vol.182 , pp. 655-666
    • Vidal, S.M.1    Tremblay, M.L.2    Govoni, G.3    Gauthier, S.4    Sebastiani, G.5    Malo, D.6
  • 30
    • 0028720467 scopus 로고
    • Cytomegalovirus Plasmid Vectors for Permanent Lines of Polarized Epithelial Cells
    • New York: Academic Press
    • Brewer CB. Cytomegalovirus Plasmid Vectors for Permanent Lines of Polarized Epithelial Cells. In: Methods in Cell Biology, vol 43. New York: Academic Press, 1994.
    • (1994) Methods in Cell Biology , vol.43
    • Brewer, C.B.1
  • 31
    • 0030767804 scopus 로고    scopus 로고
    • Cell-specific and inducible Nramp1 gene expression in mouse macrophagesin vitro and in vivo
    • Govoni G, Gauthier S, Billia F, Iscove NN, Gros P. Cell-specific and inducible Nramp1 gene expression in mouse macrophagesin vitro and in vivo. J Leukoc Biol 1997;62:277-86.
    • (1997) J Leukoc Biol , vol.62 , pp. 277-286
    • Govoni, G.1    Gauthier, S.2    Billia, F.3    Iscove, N.N.4    Gros, P.5
  • 32
    • 0031051831 scopus 로고    scopus 로고
    • The human NRAMP1 gene, as a marker of professional primary phagocytes: Studies in blood cells, and in HL-60 promyelocytic leukemia
    • Cellier M, Shustik C, Dalton W, Rich E, Hu J, Malo D, et al. The human NRAMP1 gene, as a marker of professional primary phagocytes: studies in blood cells, and in HL-60 promyelocytic leukemia. J Leukoc Biol 1997; 61:96-105.
    • (1997) J Leukoc Biol , vol.61 , pp. 96-105
    • Cellier, M.1    Shustik, C.2    Dalton, W.3    Rich, E.4    Hu, J.5    Malo, D.6
  • 34
    • 0031033088 scopus 로고    scopus 로고
    • Natural resistance to infection with intracellular parasites: The Nramp1 protein is recruited to the membrane of the phagosome
    • Gruenheid S, Pinner E, Desjardins M, Gros P. Natural resistance to infection with intracellular parasites: The Nramp1 protein is recruited to the membrane of the phagosome. J Exp Med 1997; 185:717-30.
    • (1997) J Exp Med , vol.185 , pp. 717-730
    • Gruenheid, S.1    Pinner, E.2    Desjardins, M.3    Gros, P.4
  • 35
    • 0028909199 scopus 로고
    • Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited
    • Clemens DL, Horwitz MA. Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J Exp Med 1995;181:257-70.
    • (1995) J Exp Med , vol.181 , pp. 257-270
    • Clemens, D.L.1    Horwitz, M.A.2
  • 37
    • 0027375512 scopus 로고
    • Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells
    • Garcia-del Portillo F, Zwick MB, Leung KY, Finlay BB. Salmonella induces the formation of filamentous structures containing lysosomal membrane glycoproteins in epithelial cells. Proc Natl Acad Sci USA 1993;90:10544-8.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10544-10548
    • Garcia-del Portillo, F.1    Zwick, M.B.2    Leung, K.Y.3    Finlay, B.B.4
  • 38
    • 0028941255 scopus 로고
    • Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors
    • Garcia-del Portillo F, Finlay BB. Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptors. J Cell Biol 1995;129:81-97.
    • (1995) J Cell Biol , vol.129 , pp. 81-97
    • Garcia-del Portillo, F.1    Finlay, B.B.2
  • 39
    • 0027977818 scopus 로고
    • Macrophage-listeria interactions
    • Campbell PA. Macrophage-listeria interactions. Immunol Series 1994; 60: 313-28.
    • (1994) Immunol Series , vol.60 , pp. 313-328
    • Campbell, P.A.1
  • 40
    • 0029278789 scopus 로고
    • Cloning and characterization of a second human NRAMP gene on chromosome 12q13
    • Vidal SM, Belouchi AM, Cellier M, Beatty B, Gros P. Cloning and characterization of a second human NRAMP gene on chromosome 12q13. Mamm Genome 1995;6:224-30.
    • (1995) Mamm Genome , vol.6 , pp. 224-230
    • Vidal, S.M.1    Belouchi, A.M.2    Cellier, M.3    Beatty, B.4    Gros, P.5
  • 41
    • 0028962892 scopus 로고
    • Identification and characterization of a second mouse Nramp gene
    • Gruenheid S, Cellier M, Vidal S, Gros P. Identification and characterization of a second mouse Nramp gene. Genomics 1995; 25:514-25.
    • (1995) Genomics , vol.25 , pp. 514-525
    • Gruenheid, S.1    Cellier, M.2    Vidal, S.3    Gros, P.4
  • 42
    • 0028784711 scopus 로고
    • The natural resistance associated macrophage protein (Nramp) defines a new family of membrane proteins conserved throughout evolution
    • Cellier M, Prive G, Belouchi A, et al. The natural resistance associated macrophage protein (Nramp) defines a new family of membrane proteins conserved throughout evolution. Proc Natl Acad Sci USA 1995;92:10089-94.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10089-10094
    • Cellier, M.1    Prive, G.2    Belouchi, A.3
  • 43
    • 0029071823 scopus 로고
    • Structural conservation of ion conduction pathways in K+ channels and glutamate receptors
    • Wood MW, Vandongen HMA, Vandongen AMJ. Structural conservation of ion conduction pathways in K+ channels and glutamate receptors. Proc Natl Acad Sci USA 1995;92: 4882-6.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4882-4886
    • Wood, M.W.1    Vandongen, H.M.A.2    Vandongen, A.M.J.3
  • 44
    • 0030755366 scopus 로고    scopus 로고
    • Cloning and characterization of a mammalian proton-coupled metal-ion transporter
    • Gunshin H, Mackenzie B, Berger UB, Gushin Y, Romero MF, Boron WF, et al. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 1997;388:482-8.
    • (1997) Nature , vol.388 , pp. 482-488
    • Gunshin, H.1    Mackenzie, B.2    Berger, U.B.3    Gushin, Y.4    Romero, M.F.5    Boron, W.F.6
  • 47
    • 0029978512 scopus 로고    scopus 로고
    • A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria
    • Supek F, Supekova L, Nelson H, Nelson N. A yeast manganese transporter related to the macrophage protein involved in conferring resistance to mycobacteria. Proc Natl Acad Sci USA 1996;93:5105-10.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5105-5110
    • Supek, F.1    Supekova, L.2    Nelson, H.3    Nelson, N.4
  • 48
    • 0030684012 scopus 로고    scopus 로고
    • Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family
    • Pinner E, Gruenheid S, Raymond M, Gros P. Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family. J Biol Chem 1997; 272:28933-8.
    • (1997) J Biol Chem , vol.272 , pp. 28933-28938
    • Pinner, E.1    Gruenheid, S.2    Raymond, M.3    Gros, P.4
  • 49
    • 0028099694 scopus 로고
    • Human natural resistance-associated macrophage protein: CDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression
    • Cellier M, Govoni G, Vidal SM, Kwan T, Groulx N, Liu J, et al. Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression. J Exp Med 1994;180: 1741-52.
    • (1994) J Exp Med , vol.180 , pp. 1741-1752
    • Cellier, M.1    Govoni, G.2    Vidal, S.M.3    Kwan, T.4    Groulx, N.5    Liu, J.6
  • 50
    • 0028915859 scopus 로고
    • Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene
    • Liu J, Fujiwara TM, Buu NT, Sanchez FO, Cellier M, Paradis AJ, et al. Identification of polymorphisms and sequence variants in the human homologue of the mouse natural resistance-associated macrophage protein gene. Am J Hum Genet 1995; 56:845-53.
    • (1995) Am J Hum Genet , vol.56 , pp. 845-853
    • Liu, J.1    Fujiwara, T.M.2    Buu, N.T.3    Sanchez, F.O.4    Cellier, M.5    Paradis, A.J.6
  • 51
    • 0029088270 scopus 로고
    • Identification of a highly polymorphic length variant in the 3′UTR of NRAMP1
    • Buu NT, Cellier M, Gros P, Schurr E. Identification of a highly polymorphic length variant in the 3′UTR of NRAMP1. Immunogenetics 1995;42:428-9.
    • (1995) Immunogenetics , vol.42 , pp. 428-429
    • Buu, N.T.1    Cellier, M.2    Gros, P.3    Schurr, E.4
  • 52
    • 0028609161 scopus 로고
    • Genetic and physical mapping of 2q35 in the region of the NRAMP and IL8R genes: Identification of a polymorphic repeat in exon 2 of NRAMP
    • White JK, Shaw MA, Barton CH, Cerretti DP, Williams H, Morck BA, et al. Genetic and physical mapping of 2q35 in the region of the NRAMP and IL8R genes: Identification of a polymorphic repeat in exon 2 of NRAMP. Genomics 1994; 24:295-302.
    • (1994) Genomics , vol.24 , pp. 295-302
    • White, J.K.1    Shaw, M.A.2    Barton, C.H.3    Cerretti, D.P.4    Williams, H.5    Morck, B.A.6
  • 53
    • 0029171790 scopus 로고
    • Genomic organization and sequence of the human NRAMP gene: Identification and mapping of a promoter region polymorphism
    • Blackwell JM, Barton CH, White JK, Searle S, Baker AM, Williams H, et al. Genomic organization and sequence of the human NRAMP gene: Identification and mapping of a promoter region polymorphism. Mol Med 1995;1:194-205.
    • (1995) Mol Med , vol.1 , pp. 194-205
    • Blackwell, J.M.1    Barton, C.H.2    White, J.K.3    Searle, S.4    Baker, A.M.5    Williams, H.6
  • 55
    • 0030802663 scopus 로고    scopus 로고
    • No evidence for linkage between leprosy susceptibility and the human natural resistance-associated macrophage protein 1 (NRAMP1) gene in French Polynesia
    • Roger M, Levee G, Chanteau S, Gicquel B, Schurr E. No evidence for linkage between leprosy susceptibility and the human natural resistance-associated macrophage protein 1 (NRAMP1) gene in French Polynesia. Int J Lepr Other Mycobact Dis 1997;65:197-202.
    • (1997) Int J Lepr Other Mycobact Dis , vol.65 , pp. 197-202
    • Roger, M.1    Levee, G.2    Chanteau, S.3    Gicquel, B.4    Schurr, E.5
  • 56
    • 0027716924 scopus 로고
    • An RFLP map for 2q33-q37 from multicase mycobacterial and leishmanial disease families: No evidence for an Lsh/Ity/Bcg gene homologue influencing susceptibility to leprosy
    • Shaw MA, Atkinson S, Dockrell H, Hussain R, Lins-Lainson Z, Shaw J, et al. An RFLP map for 2q33-q37 from multicase mycobacterial and leishmanial disease families: No evidence for an Lsh/Ity/Bcg gene homologue influencing susceptibility to leprosy. Ann Hum Genet 1993;57:251-71.
    • (1993) Ann Hum Genet , vol.57 , pp. 251-271
    • Shaw, M.A.1    Atkinson, S.2    Dockrell, H.3    Hussain, R.4    Lins-Lainson, Z.5    Shaw, J.6
  • 57
    • 0028610051 scopus 로고
    • Genetic control of susceptibility to leprosy in French Polynesia: No evidence for linkage with markers on telomeric human chromosome 2
    • Levee G, Liu J, Gicquel B, Chanteau S, Schurr E. Genetic control of susceptibility to leprosy in French Polynesia: No evidence for linkage with markers on telomeric human chromosome 2. Int J Lepr Other Mycobact Dis 1994;62:499-511.
    • (1994) Int J Lepr Other Mycobact Dis , vol.62 , pp. 499-511
    • Levee, G.1    Liu, J.2    Gicquel, B.3    Chanteau, S.4    Schurr, E.5
  • 60
    • 0031019261 scopus 로고    scopus 로고
    • Analysis of the candidate gene NRAMP1 in the first 61 ARC National Repository families for rheumatoid arthritis
    • Shaw MA, Clayton D, Blackwell JM. Analysis of the candidate gene NRAMP1 in the first 61 ARC National Repository families for rheumatoid arthritis. J Rheumatol 1997;24:212-4.
    • (1997) J Rheumatol , vol.24 , pp. 212-214
    • Shaw, M.A.1    Clayton, D.2    Blackwell, J.M.3
  • 61
    • 0031002687 scopus 로고    scopus 로고
    • Linkage and association studies of the natural resistance-associated macrophage protein 1 (NRAMP1) locus in rheumatoid arthritis
    • John S, Marlow A, Hajeer A, Ollier W, Silman A, Worthington J. Linkage and association studies of the natural resistance-associated macrophage protein 1 (NRAMP1) locus in rheumatoid arthritis. J Rheumatol 1997;24:452-7.
    • (1997) J Rheumatol , vol.24 , pp. 452-457
    • John, S.1    Marlow, A.2    Hajeer, A.3    Ollier, W.4    Silman, A.5    Worthington, J.6
  • 62
    • 0027486682 scopus 로고
    • Epistatic modelling in rheumatoid arthritis: An application of the Risch theory
    • Rigby AS, Voelm L, Silman AJ. Epistatic modelling in rheumatoid arthritis: An application of the Risch theory. Genet Epidemiol 1993;10:311-20.
    • (1993) Genet Epidemiol , vol.10 , pp. 311-320
    • Rigby, A.S.1    Voelm, L.2    Silman, A.J.3
  • 64
    • 0027100466 scopus 로고
    • HLA-DR4, mycobacteria, heat shock proteins, and rheumatoid arthritis
    • Rook G, McCulloch J. HLA-DR4, mycobacteria, heat shock proteins, and rheumatoid arthritis. Arthritis Rheum 1992;35: 1409-12.
    • (1992) Arthritis Rheum , vol.35 , pp. 1409-1412
    • Rook, G.1    McCulloch, J.2


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