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Overlapping epitopes encompassing a point mutation (12Gly → Arg) in p21 ras can be recognized by HLA-DR. -DP, and -DQ restricted T cells
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- T cells from a patient with colon carcinoma, specific for a mutant p21 ras derived peptide (13Gly → Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation
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- T cells from a patient with colon carcinoma, specific for a mutant p21 ras derived peptide (13Gly → Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation. Cancer. Immunol. Immunother. 40, 165-172 (1995).
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Memory T cells of a patient with follicuiar thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln → Leu61)
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GEDDE-DAHL III, T., SPURKLAND, A., ERIKSEN, J.A., THORSBY, E. and GAUDERNACK, G., Memory T cells of a patient with follicuiar thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln → Leu61). Int. Immunol., 4, 1331-1337 (1992b).
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T cell epitopes encompassing the mutational hot spot position 61 of p21 ras. Promiscuity in ras peptide binding to HLA
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