Humoral immunity to Borrelia burgdorferi N40 decorin binding proteins during infection of laboratory mice

Infection and Immunity

Volumn 66, Issue 6, 1998, Pages 2827-2835

  Feng, Sunlian ^a   Hodzic, Emir ^a   Stevenson, Brian ^b   Barthold, Stephen W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DECORIN;

ANIMAL EXPERIMENT; ARTICLE; BACTERIUM IDENTIFICATION; BORRELIA BURGDORFERI; BORRELIA INFECTION; GENE EXPRESSION; GENE SEQUENCE; HOST RESISTANCE; HUMORAL IMMUNITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

EID: 0031812337     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.6.2827-2835.1998     Document Type: Article

References (49)

1. Akins, D. R., S. F. Porcella, T. G. Popova, D. Shevchenko, S. I. Baker, M. Li, M. V. Norgard, and J. D. Radolf. 1995. Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue. Mol. Microbiol. 18:507-520.
2. Anderson, J. F., S. W. Barthold, and L. A. Magnarelli. 1990. Infectious but nonpathogenic isolate of Borrelia burgdorferi. J. Clin. Microbiol. 28:2693-2699.
3. Armstrong, A. L., S. W. Barthold, O. H. Persing, and D. S. Beck. 1992. Carditis in Lyme disease susceptible and resistant strains of laboratory mice infected with Borrelia burgdorferi. Am. J. Trop. Med. Hyg. 47:249-258.
4. Assous, M. V., D. Postic, G. Paul, P. Nevot, and G. Baranton. 1994. Individualisation of two genomic groups among American Borrelia burgdorferi sensu lato. FEMS Microbiol. Lett. 121:93-98.
5. Barbour, A. G. 1984. Isolation and cultivation of Lyme disease spirochetes. Yale J. Biol. Med. 57:521-525.
6. Barthold, S. W, 1991. Infectivity of Borrelia burgdorferi relative to route of inoculation and genotype in laboratory mice. J. Infect. Dis. 163:419-420.
7. Barthold, S. W., and L. K. Bockenstedt. 1993. Passive immunizing activity of sera from mice infected with Borrelia burgdoferi. Infect. Immun. 61:4696-4702.
8. Barthold, S. W., M. S. deSouza, J. L. Janotka, A. L. Smith, and D. H. Persing. 1993. Chronic Lyme borreliosis in the laboratory mouse. Am. J. Pathol. 143:951-971.
9. Barthold, S. W., S. Feng, L. K. Bockenstedt, E. Fikrig, and K. Feen. 1997. Protective and arthritis-resolving activity in serum from mice infected with Borrelia burgdorferi. Clin. Infect. Dis. 25:S9-S17.
10. Barthold, S. W., E. Fikrig, L. K. Bockenstedt, and D. H. Persing. 1995. Circumvention of outer surface protein A immunity by host-adapted Borrelia burgdorferi. Infect. Immun. 63:2255-2261.
11. Barthold, S. W., S. A. Levy, E. Fikrig, L. K. Bockenstedt, and A. L. Smith. 1995. Serologic response of naturally exposed or vaccinated dogs to Borrelia burgdorferi, the agent of Lyme borreliosis. J. Am. Vet. Med. Assoc. 207:1435-1440.
12. Barthold, S. W., D. H. Persing, A. L. Armstrong, and R. A. Peeples. 1991. Kinetics of Borrelia burgdorferi dissemination and evolution of disease following intradermal inoculation of mice. Am. J. Pathol. 139:263-273.
13. Bergstrom, S., V. Bundoc, and A. G. Barbour. 1989. Molecular analysis of linear plasmid encoded major surface proteins. OspA and OspB, of the Lyme disease spirochete Borrelia burgdorferi. Mol. Microbiol. 3:479-485.
14. Bockenstedt, L. K., E. Hodzic, S. Feng, K. W. Bourell, A. deSilva, R. Montgomery, J. D. Radolf, and S. W. Barthold. 1997. Borrelia burgdorferi strainspecific OspC-mediated immunity in mice. Infect. Immun. 65:4661-4667.
15. Burkot, T. R., J. Piesman, and R. A. Wirtz. 1994. Kinetics of the Borrelia burgdorferi outer surface protein A (OspA) in the tick, Ixodes scapularis, p. 224-227. In R. Cevinini, V. Sambri, and M. LaPlaca (ed.), Advances in Lyme borreliosis research. Proceedings of the VI International Conference on Lyme Borreliosis. University of Bologna, Bologna, Italy.
16. Champion, C. I., D. R. Blanco, J. T. Skare, D. A. Haake, M. Giladi, D. Foley, J. N. Miller, and M. A. Lovett. 1994. A 9.0 kilobase-pair circular plasmid of Borrelia burgdorferi encodes an exported protein: evidence for expression only during infection. Infect. Immun. 62:2653-2661.
17. Coleman, J. L., and J. L. Benach. 1992. Characterization of antigenic determinants of Borrelia burgdorferi shared by other bacteria. J. Infect. Dis. 165: 658-666.
18. Craft, J. E., R. L. Grodzicki, and A. C. Steere. 1984. Antibody response in Lvme disease: evaluation of diagnostic tests. J. Infect. Dis. 149:789-795.
19. deSilva, A., E. Fikrig, E. Hodzic, S. R. Telford III, and S. W. Barthold. 1998. Immune evasion by tick-borne and host-adapted Borrelia burgdorferi. J. Infect. Dis. 177:395-400.
20. deSilva, A., S. R. Telford, L. R. Brunet, S. W. Barthold, and E. Fikrig. 1996. Borrelia burgdorferi OspA arthropod-specific transmission-blocking Lyme disease vaccine. J. Exp. Med. 183:271-275.
21. Dressler, F., J. A. Whalen, B. N. Reinhardt, and A. C. Steere. 1993. Western blotting in the serodiagnosis of Lyme disease. J. Infect. Dis. 167:392-400.
22. Dunn, J. J., B. N. Lade, and A. G. Barbour. 1990. Outer surface protein A (OspA) from the Lyme disease spirochete, Borrelia burgdorferi: high level expression and purification of a soluble recombinant form of OspA. Protein Expression Purif. 1:159-168.
23. Feng, S. L., S. Das, T. Lam, R. A. Flavell, and E. Fikrig. 1995. A 55-kilodalton antigen encoded by a gene on a Borrelia burgdorferi 49-kilobase plasmid is recognized by antibodies in sera from patients with Lyme disease. Infect. Immun. 63:3459-3466.
24. Ferdows, M. S., and A. G. Barbour. 1989. Megabase-sized linear DNA in the bacterium Borrelia burgdorferi, the Lyme disease agent. Proc. Natl. Acad. Sci. USA 86:5969-5973.
25. Fikrig, E., S. W. Barthold, F. S. Kantor, and R. A. Flavell. 1990. Protection of mice against the Lyme disease agent by immunizing with recombinant OspA. Science 250:553-556.
26. Fikrig, E., S. W. Barthold, N. Marcantonio, K. Deponte, F. S. Kantor, and R. A. Flavell. 1992. Roles of OspA, OspB, and flagellin in protective immunity to Lyme borreliosis in laboratory mice. Infect. Immun. 60:657-661.
27. Fikrig, E., S. W. Barthold, W. Sun, W. Feng, S. R. Telford III, and R. A. Flavell. 1997. Borrelia burgdorferi P35 and P37 proteins, expressed in vivo, elicit protective immunity. Immunity 6:531-539.
28. Fraser, C. M., S. Casjens, W. M. Huang, G. G. Sutton, R. Clayton, R. Lathigra, O. White, K. A. Ketchum, R. Dodson, E. K. Hickey, M. Gwinn, B. Dougherty, J.-F. Tomb, R. D. Fleishman, D. Richardson, J. Peterson, A. R. Kerlavage, J. Quackenbush, S. Salzberg, M. Hanson, R. van Vugt, N. Palmer, M. D. Adams, J. Gocayne, J. Weidman, T. Utterback, L. Watthey, L. McDonald, P. Artiach, C. Bowman, S. Garland, C. Fujii, M. D. Cotton, K. Horst, K. Roberts, B. Hatch, H. O. Smith, and J. C. Venter. 1997. Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390: 580-586.
29. Guo, B. P., S. J. Norris, L. C. Rosenberg, and M. Hook. 1995. Adherence of Borrelia burgdorferi to the proteoglycan decorin. Infect. Immun. 63:3467-3472.
30. Lam, T. T., T. K. Nguyen, E. Fikrig, and R. A. Flavell. 1994. A chromosomal Borrelia burgdorferi gene encodes a 22-kDa putative lipoprotein (P22) that is serologically recognized in Lyme disease. J. Clin. Microbiol. 32:876-883.
31. Lam, T. T., T. K. Nguyen, R. R. Montgomery, F. S. Kantor, E. Fikrig, and R. A. Flavell. 1994. Outer surface proteins E and F of Borrelia burgdorferi, the agent of Lyme disease. Infect. Immun. 62:290-298.
32. LeFebvre, R. B., W. S. Probert, and G.-C. Perng. 1993. Characterization of a chromosomal gene and the antigen it expresses from the Lyme disease agent, Borrelia burgdorferi. J. Clin. Microbiol. 31:2146-2151.
33. Luft, B. J., W. Jiang, P. Munoz, R. J. Dattwyler, and P. D. Gorevic. 1989. Biochemical and immunological characterization of the surface proteins of Borrelia burgdorferi. Infect. Immun. 57:3637-3645.
34. Mathiesen, D. A., J. H. Oliver, C. P. Kolbert, E. Tullson, B. J. Johnson, G. L. Campbell, P. D. Mitchell, K. D. Reed, S. R. Telford III, J. F. Anderson, R. S. Lane, and D. H. Persing. 1997. Genetic heterogeneity of Borrelia burgdorferi in the United States. J. Infect. Dis. 175:98-107.
35. Montgomery, R. A., K. Feen, S. E. Malawista, and L. K. Bockenstedt. 1996. Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease. J. Exp. Med. 183:261-269.
36. Preac-Mursic, V., B. Wilske, E. Patsouris, S. Javris, S. Will, E. Southchek, S. Rainhardt, S. Lehert, U. Klockmann, and P. Mehrain. 1992. Active immunization with pC protein of Borrelia burgdorferi protects gerbils against B. burgdorferi infection. Infection 20:342-349.
37. Schwan, T. G., J. Piesman, W. T. Golde, M. C. Dolan, and P. A. Rosa. 1995. Induction of outer surface protein on Borrelia burgdorferi during tick-feeding. Proc. Natl. Acad. Sci. USA 92:2909-2913.
38. Sears, J. E., E. Fikrig, T. Y. Nakagawa, K. Deponte, N. Marcantonio, F. S. Kantor, and R. A. Flavell. 1991. Molecular mapping of OspA-mediated immunity against Borrelia burgdorferi, the agent of Lyme disease. J. Immunol. 147:1995-2001.
39. Simpson, W. J., W. Burgdorfer, M. E. Schrumpf, R. H. Karstens, and T. G. Schwan. 1991. Antibody to a 39-kilodalton Borrelia burgdorferi antigen (P39) as a marker for infection in experimentally and naturally inoculated animals. J. Clin. Microbiol. 29:236-243.
40. Simpson, W. J., W. Cieplak, M. E. Schrumpf, A. G. Barbour, and T. G. Schwan. 1994. Nucleotide sequence and analysis of the gene in Borrelia burgdorferi encoding the immunogenic P39 antigen. FEMS Microbiol. Lett. 119:381-388.
41. Simpson, W. J., M. E. Schrumpf, S. F. Haves, and T. G. Schwan. 1991. Molecular and immunological analysis of a polymorphic periplasmic protein of Borrelia burgdorferi. J. Clin. Microbiol. 29:1940-1948.
42. Southern, E. M. 1975. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:503-517.
43. Stevenson, B., L. K. Bockenstedt, and S. W. Barthold. 1994. Expression and gene sequence of outer surface protein C of Borrelia burgdorferi reisolated from chronically infected mice. Infect. Immun. 62:3568-3571.
44. Stevenson, B., S. Casjens, R. van Vugt, S. F. Porcella, K. Tilly, J. L. Bono, and P. Rosa. 1997. Characterization of cp18, a naturally truncated member of the cp32 family of Borrelia burgdorferi plasmids. J. Bacteriol. 179:4285-4291.
45. Stevenson, B., K. Tilly, and P. A. Rosa. 1996. A family of genes located on four separate 32-kilobase circular plasmids in Borrelia burgdorferi B31. J. Bacteriol. 178:3508-3516.
46. Suk, K., S. Das, W. Sun, B. Jwang, S. W. Barthold, R. A. Flavell, and E. Fikrig. 1995. Borrelia burgdorferi genes selectively expressed in the infected host. Proc. Nail. Acad. Sci. USA 92:4269-1273.
47. Wallich, R., C. Brenner, M. D. Kramer, and M. M. Simon. 1995. Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo. Infect. Immun. 63:3327-3335.
48. Wallich, R., M. M. Simon, H. Hofmann, S. E. Moter, U. E. Schaible, and M. D. Kramer. 1993. Molecular and immunological characterization of a novel polymorphic lipoprotein of Borrelia burgdorferi. Infect. Immun. 61: 4158-4166.
49. Wilske, B., V. Fingerle, V. PreacMursic, S. JaurisHeipke, A. Hoffman, H. Loy, H. W. Pfister, D. Rossler, and E. Soutschek. 1994. Immunoblot using recombinant antigens derived from different genospecies of Borrelia burgdorferi sensu lato. Med. Microbiol. Immunol. 183:43-59.