Interleukin-1 and neurodegeneration

Neuroscientist

Volumn 4, Issue 3, 1998, Pages 195-201

  Rothwell, Nancy J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cytokines; Interleukin 1; Neurodegeneration

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRAIN INJURY; CONTROLLED STUDY; DRUG MECHANISM; INFLAMMATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MIDDLE CEREBRAL ARTERY OCCLUSION; MULTIPLE SCLEROSIS; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; RAT; REVIEW; STROKE;

EID: 0031807781     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385849800400315     Document Type: Review

References (37)

1. Kluger MJ. Fever: role of endogenous pyrogens and cryogens. Physiol Rev 1991;71:93-127.
2. Yuan J, Shaham M, Ledoux S, Ellis HM, Horvitz HR. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 1993;75:641-652.
3. Dinarello CA. The biological properties of interleukin-1 antagonist. Blood 1994;77:1627-1652.
4. Sims JE, Gayle MA, Slack JL, et al. Interleukin 1 signaling occurs exclusively via the type 1 receptor. Proc Natl Acad Sci U S A 1993;90:6155-6159.
5. Rothwell NJ, Luheshi G, Toulmond S. Cytokines and their receptors in the central nervous system: physiology, pharmacology and pathology. Pharmacol Ther 1996;69:85-95.
6. Liu C, Takao T, Hashimoto K, De Souza EB. Interleukin-1 receptors in the nervous system. In: Rothwell NJ, editor. Cytokines and the nervous system. Austin (TX): RG Landes; 1996. p. 21-34.
7. Hopkins SJ, Rothwell NJ. Cytokines in the nervous system I: expression and recognition. Trends Neurosci 1995;18:83-88.
8. Liu T, McDonnell PC, Young PR, et al. Interleukin-1 beta mRNA expression in ischemic rat cortex. Stroke 1993;24:1746-1750.
9. Taupin V, Toulmond S, Serrano A, Benavides J, Zavala F. Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. J Neuroimmunol 1993;42:177-186.
10. Ianotti F, Kida S, Weller R, Buhagier G, Hillhouse E. Interleukin-1b in focal cerebral ischemia in rats. J Cereb Blood Flow Metab 1993;13:S125.
11. Bhat RV, DiRocco R, Marcy VR, et al. Increased expression of IL-1 converting enzyme in hippocampus after ischemia: selective localization in microglia. J Neurosci 1996;16:4146-4153.
12. Rothwell NJ, editor. Cytokine in the nervous system. Austin (TX): Springer/RG Landes; 1996.
13. Rothwell NJ. Cytokines in Alzheimer's and other neurodegenerative diseases. In: Turner JD, Beyreuther K, Theuring F, editors. Alzheimer's Disease, Ernst Schering Research Foundation Workshop. Berlin: Springer-Verlag; 1996. p. 127-146.
14. Toulmond S, Rothwell NJ. Time course of IL-1 receptor antagonist (IL-1ra) expression after brain trauma in the rat (abstract). Soc Neurosci Abstr 1995;21:200-202.
15. Strijbos PJLM, Rothwell NJ. Interleukin-1β attenuates excitatory amino acid induced neurodegeneration in vitro: involvement of nerve growth factor. J Neurosci 1995;15:3468-3474.
16. Relton JK, Rothwell NJ. Interleukin-1 receptor antagonist inhibits ischemic and excitotoxic neuronal damage in the rat. Brain Res Bull 1992;29:43-46.
17. Loddick SA, Rothwell NJ. Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischemia in the rat. J Cereb Blood Flow Metab 1996;16:932-940.
18. Chen HY, Trumbauer ME, Grabiec CC, et al. Transgenic mice expressing human interleukin-1β exhibited runted phenotype and pathology in various tissues. J Cell Biochem 1994;18A:283.
19. Relton JK, Martin D, Thompson RC, Russell DA. Peripheral administration of interleukin-1 receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat. Exp Neurol 1995; 138:206-212.
20. Garcia JH, Liu KF, Relton JK. Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion. Am J Pathol 1995;147:1477-1485.
21. Betz AL, Yang G-Y, Davidson BL. Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain. J Cereb Blood Flow Metab 1995;15:547-551.
22. Rothwell NJ, Loddick SA, Stroemer P. Interleukins and cerebral ischaemia. Int Rev Neurobiol 1997;40:281-298.
23. Stroemer RP, Rothwell NJ. Cortical protection by localized striatal injection of IL-1ra following cerebral ischemia in the rat. J Cereb Blood Flow Metab 1997;17:597-604.
24. Yamasaki Y, Matsuura N, Shozuhara H, Onodera H, Itoyama Y, Kogure K. Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke 1995;26:676-681.
25. Loddick SA, MacKenzie A, Rothwell NJ. An ICE inhibitor, z-VAD-DCB, attenuates ischemic brain damage in the rat. Neuroreport 1996;7:1465-1468.
26. Friedlander RM, Gagliardini V, Hara H, et al. Expression of a dominant negative mutant of interleukin-1β converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury. J Exp Med. 1997; 185:933-940.
27. Betz L, Schielke GP, Yang G-Y. Interleukin-1 in cerebral ischemia. Keio J Med 1996;45:230-237.
28. Friedlander RM, Gagliardini V, Rotello RJ, Yuan J. Functional role of interleukin 1β (IL-1β) in IL-1β-converting enzyme-mediated apoptosis. J Exp Med 1996;184:717-724.
29. Troy CM, Stefanis L, Prochiantz A, Green LA, Shelanski ML. The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by SODI downregulation. Proc Natl Acad Sci U S A 1996;93:5635-5640.
30. Martin D, Relton JK, Miller G, Bendele A, Fischer N, Russell D. Cytokines as therapeutic agents in neurological disorders. In: Rothwell NJ, editor. Cytokines and the nervous system. Austin (TX): RG Landes; 1996. p. 163-169.
31. Toumond S, Rothwell NJ. Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat. Brain Res 1995;671:261-266.
32. Royston MC, Rothwell NJ, Roberts GW. Alzheimer's disease: pathology to potential treatments. Trends Pharmacol Sci 1992;13: 45-46.
33. Vandenabeele P, Fiers W. Is amyloidogenesis during Alzheimer's disease due to an IL-1/IL-6 mediated acute phase response in the brain? Immunol Today 1991;12:207-219.
34. Marquette C, Van Dam AM, Ban E, et al. Rat interleukin-1 beta binding sites in rat hypothalamus and pituitary gland. Neuroendocrinology 1995;62;362-369.
35. O'Neill LAJ. Towards an understanding of the signal transduction pathways for interleukin-1. Biochim Biophys Acta 1995;1266:31-44.
36. Chao CC, Hu S, Sheng WS, Bu D, Bukrinsky MI, Peterson PK. Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia 1996;16:276-284.
37. Gutierrez EG, Banks WA, Kastin AJ. Blood-borne interleukin-1 receptor antagonist crosses the blood brain barrier. J Neuroimmunol 1994;55:153-160.