Functional conservation of the transportin nuclear import pathway in divergent organisms

Molecular and Cellular Biology

Volumn 18, Issue 7, 1998, Pages 4141-4148

  Siomi, Mikiko C ^a   Fromont, Micheline ^b   Rain, Jean Christophe ^b   Wan, Lili ^a   Wang, Fan ^a   Legrain, Pierre ^b   Dreyfuss, Gideon ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RNA BINDING PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE ISOLATION; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA PROCESSING; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; XENOPUS LAEVIS;

ANIMALIA; DROSOPHILA MELANOGASTER; MAMMALIA; MELANOGASTER; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; XENOPUS LAEVIS;

EID: 0031806105     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.7.4141     Document Type: Article

References (48)

1. Adam, S. A., R. S. Marr, and L. Gerace. 1990. Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J. Cell Biol. 111:807-816.
2. Aitchison, J. D., G. Blobel, and M. P. Rout. 1996. Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins. Science 274:624-627.
3. Anderson, J. T., S. M. Wilson, K. V. Dater, and M. S. Swanson. 1993. NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability. Mol. Cell. Biol. 13:2730-2741.
4. Bischof, F. R., and D. Görlich. 1997. RanBP1 is crucial for the release of RanGTP from importin β-related nuclear transport factors. FEBS Lett. 419: 249-254.
5. Bischoff, F. R., S. Nakielny, and G. Dreyfuss. Unpublished results.
6. Bonifaci, N., J. Moroianu, A. Radu, and G. Blobel. 1997. Karyopherin β2 mediates nuclear import of a mRNA binding protein. Proc. Natl. Acad. Sci. USA 94:5055-5060.
7. Burd, C. G., and G. Dreyfuss. 1994. RNA binding specificity of hnRNP A1: hnRNP A1 high-affinity binding sites in pre-mRNA splicing. EMBO J. 13: 1197-1204.
8. Caceres, J. F., S. Stamm, D. M. Helfman, and A. R. Krainer. 1994. Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science 265:1706-1709.
9. Chi, N. C., and S. A. Adam. 1997. Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear pore. Mol. Biol. Cell 8:945-956.
10. Dingwall, C., and R. A. Laskey. 1991. Nuclear targeting sequences - a consensus? Trends Biochem. Sci. 16:478-481.
11. Dreyfuss, G., M. J. Matunis, S. Piñol-Roma, and C. G. Burd. 1993. hnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62:289-321.
12. Fridell, R. A., R. Truant, L. Trorne, R. E. Benson, and B. R. Cullen. 1997. Nuclear import of hnRNP A1 is mediated by a novel cellular cofactor related to karyopherin-β. J. Cell Sci. 110:1325-1331.
13. Fromont-Racine, M., J.-C. Rain, and P. Legrain. 1997. Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Nat. Genet. 16:277-282.
14. Fu, X.-D., A. Mayeda, T. Maniatis, and A. R. Krainer. 1992. General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5′ and 3′ splicing site selection. Proc. Natl. Acad. Sci. USA 89: 11224-11228.
15. Görlich, D., and I. W. Mattaj. 1996. Nucleocytoplasmic transport. Science 271:1513-1518.
16. Görlich, D., M. Dabrowski, F. R. Bischoff, U. Kutay, P. Bork, E. Hartmann, S. Prehn, and E. Izaurralde. 1997. A novel class of RanGTP binding proteins. J. Cell Biol. 138:65-80.
17. Henry, M., C. Z. Borland, M. Bossie, and P. Silver. 1996. Potential RNA-binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3. Genetics 142:103-115.
18. Izaurralde, E., A. Jarmolowski, C. Beisel, I. W. Mattaj, G. Dreyfuss, and U. Fischer. 1997. A role of the M9 transport signal of hnRNP A1 in mRNA nuclear export. J. Cell Biol. 137:27-35.
19. Izaurralde, E., U. Kutay, K. Cayetano, I. W. Mattaj, and D. Görlich. 1997. The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J. 16:6535-6547.
20. Kajita, Y., J. Nakayama, M. Aizawa, and F. Ishikawa. 1995. The UUUA-specific RNA-binding protein, heterogeneous nuclear ribonucleoprotein D0; common modular structure and binding properties of the 2×RBD-Gly family. J. Biol. Chem. 270:22167-22175.
21. Kiledjian, M., and G. Dreyfuss. 1992. Primary structure of the hnRNP U protein: binding RNA through RGG box. EMBO J. 11:2655-2664.
22. Matunis, E. L., and G. Dreyfuss. Unpublished data.
23. Matunis, E. L., M. J. Matunis, and G. Dreyfuss. 1992. Characterization of the major hnRNP proteins from Drosophila melanogaster. J. Cell Biol. 116: 257-269.
24. Matunis, M. J., J. Xing, and G. Dreyfuss. 1994. The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. Nucleic Acids Res. 22:1059-1067.
25. Mayeda, A., and A. R. Krainer. 1992. Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell 68:365-375.
26. Michael, W. M., M. Choi, and G. Dreyfuss. 1995. A nuclear export signal in hnRNP A1: a signal-mediated, temperature-dependent nuclear protein export pathway. Cell 83:415-422.
27. Michael, W. M., H. Siomi, M. Choi, S. Piñol-Roma, S. Nakielny, Q. Liu, and G. Dreyfuss. 1995. Signal sequences that target nuclear import and nuclear export of pre-mRNA-binding proteins. Cold Spring Harbor Symp. Quant. Biol. 60:663-668.
28. Nakielny, S., M. C. Siomi, H. Siomi, W. M. Michael, V. Pollard, and G. Dreyfuss. 1996. Transportin: nuclear transport receptor of a novel nuclear protein import pathway. Exp. Cell Res. 229:261-266.
29. Nakielny, S., and G. Dreyfuss. 1996. The hnRNP C proteins contain a nuclear retention sequence that can override nuclear export signals. J. Cell Biol. 134:1365-1373.
30. Nakielny, S., and G. Dreyfuss. 1998. Import and export of the nuclear protein import receptor, transportin, by a mechanism independent of GTP hydrolysis. Curr. Biol. 8:89-95.
31. Nakielny, S., and G. Dreyfuss. Unpublished data.
32. Pante, N., and U. Aebi. 1996. Toward the molecular dissection of protein import into nuclei. Curr. Opin. Cell Biol. 8:397-406.
33. Piñol-Roma, S., Y. D. Choi, M. J. Matunis, and G. Dreyfuss. 1988. Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins. Genes Dev. 2:215-227.
34. Piñol-Roma, S., and G. Dreyfuss. 1991. Transcription-dependent and transcription-independent nuclear transport of hnRNP proteins. Science 253: 312-314.
35. Piñol-Roma, S., and G. Dreyfuss. 1992. Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm. Nature 355:730-732.
36. Pollard, V., W. M. Michael, S. Nakielny, M. C. Siomi, F. Wang, and G. Dreyfuss. 1996. A novel receptor-mediated nuclear import pathway. Cell 86: 985-994.
37. Siomi, H., and G. Dreyfuss. 1995. A nuclear localization domain in the hnRNP A1 protein. J. Cell Biol. 129:551-559.
38. Siomi, M. C., P. S. Eder, N. Kataoka, L. Wan, Q. Liu, and G. Dreyfuss. 1997. Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins. J. Cell Biol. 138:1181-1192.
39. Swanson, M. S., T. Y. Nakagawa, K. LeVan, and G. Dreyfuss. 1987. Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-mRNA-binding proteins. Mol. Cell. Biol. 7:1731-1739.
40. Swanson, M. S., and G. Dreyfuss. 1988. Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by DNA binding proteins. Mol. Cell. Biol. 3:2237-2241.
41. Swanson, M. S., and G. Dreyfuss. 1988. RNA binding specificity of hnRNP proteins: a subset bind to the 3′ end of introns. EMBO J. 7:3519-3529.
42. + RNA binding protein. Mol. Cell. Biol. 18:1449-1458.
43. Visa, N., A. T. Alzhanova-Ericsson, X. Sun, E. Kiseleva, B. Bjorkroth, T. Wurtz, and B. Daneholt. 1996. A pre-mRNA-binding protein accompanies the RNA from the gene through the nuclear pores and into polysomes. Cell 84:253-264.
44. Vojtek, A. B., S. M. Hollenberg, and J. A. Cooper. 1993. Mammalian Ras directly interacts with the serine/threonine kinase Raf. Cell 74:205-214.
45. Wang, H., S. E. Kohalmi, and A. J. Cutler. 1996. An improved method for polymerase chain reaction using whole yeast cells. Anal. Biochem. 237:145-146.
46. Weighardt, F., G. Biamonti, and S. Riva. 1995. Nucleo-cytoplasmic distribution of human hnRNP proteins: a search for the targeting domains in hnRNP Al. J. Cell Sci. 108:545-555.
47. Weis, K., I. W. Mattaj, and A. I. Lamond. 1995. Identification of hSRP1α as a functional receptor for nuclear localization sequences. Science 268:1049-1053.
48. Yang, W., M. R. Bani, S. J. Ju, S. Rowan, Y. Ben-David, and B. Chabot. 1994. The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5′ splice site selection in vivo. Proc. Natl. Acad. Sci. USA 81:6924-6928.