-
1
-
-
0027231434
-
Translational regulation by the interferon-induced double-stranded RNA-activated 68-kDa protein kinase
-
Barber, G. N., M. Wambach, M. L. Wong, T. E. Dever, A. G. Hinnebusch, and M. G. Katze. 1993. Translational regulation by the interferon-induced double-stranded RNA-activated 68-kDa protein kinase. Proc. Natl. Acad. Sci. USA 90:4621-4625.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4621-4625
-
-
Barber, G.N.1
Wambach, M.2
Wong, M.L.3
Dever, T.E.4
Hinnebusch, A.G.5
Katze, M.G.6
-
2
-
-
0031014063
-
Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR
-
Benkirane, M., C. Neurveut, R. F. Chun, S. M. Smith, C. E. Samuel, A. Gatignol, and K.-T. Jeang. 1997. Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR. EMBO J. 16:611-624.
-
(1997)
EMBO J.
, vol.16
, pp. 611-624
-
-
Benkirane, M.1
Neurveut, C.2
Chun, R.F.3
Smith, S.M.4
Samuel, C.E.5
Gatignol, A.6
Jeang, K.-T.7
-
3
-
-
0032485912
-
Binding of the protein kinase PKR to RNAs with secondary structure defects: Role of the tandem A-G mismatch and noncontiguous helixes
-
Bevilacqua, P. C., C. X. George, C. E. Samuel, and T. R. Cech. 1998. Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes. Biochemistry 37: 6303-6316.
-
(1998)
Biochemistry
, vol.37
, pp. 6303-6316
-
-
Bevilacqua, P.C.1
George, C.X.2
Samuel, C.E.3
Cech, T.R.4
-
4
-
-
0030989529
-
Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-1 trans-activating region RNA
-
Carpick, B. W., V. Graziano, D. Schneider, R. K. Maitra, X. Lee, and B. R. G. Williams. 1997. Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-1 trans-activating region RNA. J. Biol. Chem. 272:9510-9516.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9510-9516
-
-
Carpick, B.W.1
Graziano, V.2
Schneider, D.3
Maitra, R.K.4
Lee, X.5
Williams, B.R.G.6
-
5
-
-
0030725442
-
The double-stranded RNA-dependent protein kinase PKR: Structure and function
-
Clemens, M. J., and A. Elia. 1997. The double-stranded RNA-dependent protein kinase PKR: structure and function. J. Interferon Cytokine Res. 17:503-524.
-
(1997)
J. Interferon Cytokine Res.
, vol.17
, pp. 503-524
-
-
Clemens, M.J.1
Elia, A.2
-
6
-
-
0028865525
-
Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo
-
Cosentino, G. P., S. Venkatesan, F. C. Serluca, S. R. Green, M. B. Mathews, and N. Sonenberg. 1995. Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo. Proc. Natl. Acad. Sci. USA 92:9445-9449.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9445-9449
-
-
Cosentino, G.P.1
Venkatesan, S.2
Serluca, F.C.3
Green, S.R.4
Mathews, M.B.5
Sonenberg, N.6
-
7
-
-
0030840464
-
STATs and gene regulation
-
Darnell, J. E. 1997. STATs and gene regulation. Science 277:1630-1635.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell, J.E.1
-
8
-
-
0028234529
-
Jak-STAT pathways and trancriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J. E., I. M. Kerr, and G. R. Stark. 1994. Jak-STAT pathways and trancriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell, J.E.1
Kerr, I.M.2
Stark, G.R.3
-
9
-
-
0020645073
-
Eukaryotic gene transcription with purified components
-
Dignam, J. D., P. L. Martin, B. S. Shastry, and R. G. Roeder. 1983. Eukaryotic gene transcription with purified components. Methods Enzymol. 101: 582-598.
-
(1983)
Methods Enzymol.
, vol.101
, pp. 582-598
-
-
Dignam, J.D.1
Martin, P.L.2
Shastry, B.S.3
Roeder, R.G.4
-
10
-
-
0024797894
-
Protein phosphorylation controls translation rates
-
Hershey, J. W. B. 1989. Protein phosphorylation controls translation rates. J. Biol. Chem. 264:20823-20826.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 20823-20826
-
-
Hershey, J.W.B.1
-
11
-
-
0030586859
-
Mechanism of interferon action. Structural organization of the human Pkr gene encoding an interferon-inducible RNA-dependent protein kinase (PKR) and differences from its mouse homolog
-
Kuhen, K. L., X. Shen, E. R. Carlisle, A. L. Richardson, H.-U. G. Weier, H. Tanaka, and C. E. Samuel. 1996. Mechanism of interferon action. Structural organization of the human Pkr gene encoding an interferon-inducible RNA-dependent protein kinase (PKR) and differences from its mouse homolog. Genomics 36:197-201.
-
(1996)
Genomics
, vol.36
, pp. 197-201
-
-
Kuhen, K.L.1
Shen, X.2
Carlisle, E.R.3
Richardson, A.L.4
Weier, H.-U.G.5
Tanaka, H.6
Samuel, C.E.7
-
12
-
-
0031555628
-
Isolation of the interferon-inducible RNA-dependent protein kinase Pkr promoter and identification of a novel DNA element within the 5′-flanking region of the human and mouse Pkr genes
-
Kuhen, K. L., and C. E. Samuel. 1997. Isolation of the interferon-inducible RNA-dependent protein kinase Pkr promoter and identification of a novel DNA element within the 5′-flanking region of the human and mouse Pkr genes. Virology 227:119-130.
-
(1997)
Virology
, vol.227
, pp. 119-130
-
-
Kuhen, K.L.1
Samuel, C.E.2
-
13
-
-
17444449609
-
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: Role of IRF-1 and NF-κB
-
Kumar, A., Y.-L. Yang, V. Flati, S. Der, S. Kadereit, A. Deb, J. Haque, L. Reis, C. Weissman and B. R. G. Williams. 1997. Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-κB. EMBO J. 16:406-416.
-
(1997)
EMBO J.
, vol.16
, pp. 406-416
-
-
Kumar, A.1
Yang, Y.-L.2
Flati, V.3
Der, S.4
Kadereit, S.5
Deb, A.6
Haque, J.7
Reis, L.8
Weissman, C.9
Williams, B.R.G.10
-
14
-
-
0027496739
-
Genomic structure and regulation of the promoter of the rat insulin-like growth factor binding protein-2 gene
-
Kutoh, E., J. B. Margot, and J. Schwander. 1993. Genomic structure and regulation of the promoter of the rat insulin-like growth factor binding protein-2 gene. Mol. Endocrinol. 7:1205-1216.
-
(1993)
Mol. Endocrinol.
, vol.7
, pp. 1205-1216
-
-
Kutoh, E.1
Margot, J.B.2
Schwander, J.3
-
15
-
-
0027949937
-
The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins
-
Lee, T. G., N. Tang, S. Thompson, J. Miller, and M. G. Katze. 1994. The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins. Mol. Cell. Biol. 14:2331-2342.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2331-2342
-
-
Lee, T.G.1
Tang, N.2
Thompson, S.3
Miller, J.4
Katze, M.G.5
-
16
-
-
0027178076
-
Tumor-suppressor genes: News about the interferon connection
-
Lengyel, P. 1993. Tumor-suppressor genes: news about the interferon connection. Proc. Natl. Acad. Sci. USA 90:5893-5895.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5893-5895
-
-
Lengyel, P.1
-
17
-
-
0021100710
-
High efficiency polyoma DNA transfection of chloroquine treated cells
-
Luthman, H., and G. Magnusson. 1983. High efficiency polyoma DNA transfection of chloroquine treated cells. Nucleic Acids Res. 11:1295-1308.
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 1295-1308
-
-
Luthman, H.1
Magnusson, G.2
-
18
-
-
0026716255
-
Mechanism of interferon action. Identification of an RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2α protein kinase
-
McCormack, S. J., D. C. Thomis, and C. E. Samuel 1992. Mechanism of interferon action. Identification of an RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2α protein kinase. Virology 188:47-56.
-
(1992)
Virology
, vol.188
, pp. 47-56
-
-
McCormack, S.J.1
Thomis, D.C.2
Samuel, C.E.3
-
19
-
-
0025298202
-
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
-
Meurs, E., K. Chong, J. Galabru, N. S. Thomas, I. M. Kerr, B. R. G. Williams, and A. G. Hovanessian. 1990. Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell 62:379-390.
-
(1990)
Cell
, vol.62
, pp. 379-390
-
-
Meurs, E.1
Chong, K.2
Galabru, J.3
Thomas, N.S.4
Kerr, I.M.5
Williams, B.R.G.6
Hovanessian, A.G.7
-
20
-
-
0030030724
-
Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells
-
Ortega, L. G., M. D. McCotter, G. L. Henry, S. J. MacCormack, D. C. Thomis, and C. E. Samuel. 1996. Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells. Virology 215:31-39.
-
(1996)
Virology
, vol.215
, pp. 31-39
-
-
Ortega, L.G.1
McCotter, M.D.2
Henry, G.L.3
MacCormack, S.J.4
Thomis, D.C.5
Samuel, C.E.6
-
21
-
-
0029841348
-
Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties
-
Patel, R. C., P. K. Stanton, and G. C. Sen. 1996. Specific mutations near the amino terminus of double-stranded RNA-dependent protein kinase (PKR) differentially affect its double-stranded RNA binding and dimerization properties. J. Biol. Chem. 271:25657-25663.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25657-25663
-
-
Patel, R.C.1
Stanton, P.K.2
Sen, G.C.3
-
22
-
-
0028971143
-
Matind and Matinspector - New fast and versatile tools for detection of consensus matches in nucleotide sequence data
-
Quandt, K., C. Frech, H. Karas, E. Wingender, and T. Weiner. 1995. Matind and Matinspector - new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23:4878-4884.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4878-4884
-
-
Quandt, K.1
Frech, C.2
Karas, H.3
Wingender, E.4
Weiner, T.5
-
23
-
-
0029061508
-
Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming the interferon-stimulated-gene factor 3
-
Qureshi, S. A., M. Salditt-Georgieff, and J. E. Darnell. 1995. Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming the interferon-stimulated-gene factor 3. Proc. Natl. Acad. Sci. USA 92:3829-3833.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3829-3833
-
-
Qureshi, S.A.1
Salditt-Georgieff, M.2
Darnell, J.E.3
-
24
-
-
0031899816
-
Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2α kinases PKR and GCN2
-
Romano, P. R., M. T. Garcia-Barrio, X. Zhang, Q. Wang, D. R. Taylor, F. Zhang, C. Herring, M. B. Mathews, J. Qin, and A. G. Hinnenbush. 1998. Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2α kinases PKR and GCN2. Mol. Cell Biol. 18:2282-2297.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 2282-2297
-
-
Romano, P.R.1
Garcia-Barrio, M.T.2
Zhang, X.3
Wang, Q.4
Taylor, D.R.5
Zhang, F.6
Herring, C.7
Mathews, M.B.8
Qin, J.9
Hinnenbush, A.G.10
-
25
-
-
0022372670
-
Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia
-
Saiki, R. K., S. Scharf, F. Faloona, K. B. Mullis, G. T. Horn, H. A. Erlich, and N. Arnheim. 1985. Enzymatic amplification of β-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230:1350-1354.
-
(1985)
Science
, vol.230
, pp. 1350-1354
-
-
Saiki, R.K.1
Scharf, S.2
Faloona, F.3
Mullis, K.B.4
Horn, G.T.5
Erlich, H.A.6
Arnheim, N.7
-
26
-
-
0004136246
-
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
-
Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
-
(1989)
Molecular Cloning: A Laboratory Manual, 2nd Ed.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
27
-
-
0040350202
-
Mechanism of interferon action. Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated protein kinase possessing site-specificity similar to hemin-regulated rabbit reticulocyte kinase
-
Samuel, C. E. 1979. Mechanism of interferon action. Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated protein kinase possessing site-specificity similar to hemin-regulated rabbit reticulocyte kinase. Proc. Natl. Acad. Sci. USA 76: 600-604.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 600-604
-
-
Samuel, C.E.1
-
28
-
-
0025739093
-
Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities
-
Samuel, C. E. 1991. Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 183:1-11.
-
(1991)
Virology
, vol.183
, pp. 1-11
-
-
Samuel, C.E.1
-
29
-
-
0027418321
-
The eIF-2α protein kinases, regulators of translation in eukaryotes from yeasts to humans
-
Samuel, C. E. 1993. The eIF-2α protein kinases, regulators of translation in eukaryotes from yeasts to humans. J. Biol. Chem. 268:7603-7606.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 7603-7606
-
-
Samuel, C.E.1
-
31
-
-
0029069145
-
Transcriptional responses to polypeptide ligands. The Jak-STAT pathway
-
Schindler, C., and J. E. Darnell. 1995. Transcriptional responses to polypeptide ligands. The Jak-STAT pathway. Annu. Rev. Biochem. 64:621-651.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 621-651
-
-
Schindler, C.1
Darnell, J.E.2
-
32
-
-
0026739463
-
The interferon system: A bird's eye view of its biochemistry
-
Sen, G. C., and P. Lengyel. 1992. The interferon system: a bird's eye view of its biochemistry. J. Biol. Chem. 267:5017-5020.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 5017-5020
-
-
Sen, G.C.1
Lengyel, P.2
-
33
-
-
0027999025
-
Mechanism of interferon action. Structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase
-
Tanaka, H., and C. E. Samuel. 1994. Mechanism of interferon action. Structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase. Proc. Natl. Acad. Sci. USA 91:7995-7999.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7995-7999
-
-
Tanaka, H.1
Samuel, C.E.2
-
34
-
-
3643145929
-
-
Tanaka, H., and C. E. Samuel. Unpublished data
-
Tanaka, H., and C. E. Samuel. Unpublished data.
-
-
-
-
35
-
-
10244257563
-
Autophosphorylation sites participate in the activation of the double-stranded RNA-activated protein kinase
-
Taylor, D. R., S. B. Lee, P. R. Romano, D. R. Marshak, A. G. Hinnenbush, M. Esteban, and M. B. Mathews. 1996. Autophosphorylation sites participate in the activation of the double-stranded RNA-activated protein kinase. Mol. Cell Biol. 16:6295-6302.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 6295-6302
-
-
Taylor, D.R.1
Lee, S.B.2
Romano, P.R.3
Marshak, D.R.4
Hinnenbush, A.G.5
Esteban, M.6
Mathews, M.B.7
-
36
-
-
0026716253
-
Mechanism of interferon action. cDNA structure, expression and regulation of the interferon-induced, RNA-dependent P1/eIF-2α protein kinase from human cells
-
Thomis, D. C., J. P. Doohan, and C. E. Samuel. 1992. Mechanism of interferon action. cDNA structure, expression and regulation of the interferon-induced, RNA-dependent P1/eIF-2α protein kinase from human cells. Virology 188:33-46.
-
(1992)
Virology
, vol.188
, pp. 33-46
-
-
Thomis, D.C.1
Doohan, J.P.2
Samuel, C.E.3
-
37
-
-
0026442274
-
Mechanism of interferon action: Autoregulation of RNA-dependent P1/eIF-2α protein kinase (PKR) expression in transfected mammalian cells
-
Thomis, D. C., and C. E. Samuel. 1992. Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2α protein kinase (PKR) expression in transfected mammalian cells. Proc. Natl. Acad. Sci. USA 89:10837-10841.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10837-10841
-
-
Thomis, D.C.1
Samuel, C.E.2
-
38
-
-
0027420488
-
Mechanism of interferon action: Evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR
-
Thomis, D. C., and C. E. Samuel. 1993. Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR. J. Virol. 67:7695-7700.
-
(1993)
J. Virol.
, vol.67
, pp. 7695-7700
-
-
Thomis, D.C.1
Samuel, C.E.2
-
39
-
-
0025797722
-
Transcriptional regulation of interferon-stimulated genes
-
Williams, B. R. G. 1991. Transcriptional regulation of interferon-stimulated genes. Eur. J. Biochem. 200:1-11
-
(1991)
Eur. J. Biochem.
, vol.200
, pp. 1-11
-
-
Williams, B.R.G.1
-
40
-
-
0343852938
-
Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways
-
Wong, A. H.-T., N. W. N. Tam, Y.-L. Yang, A. R. Cuddihy, S. Li, S. Kirchoff, H. Hauser, T. Decker, and A. E. Koromilas. 1997. Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways. EMBO J. 16:1291-1304.
-
(1997)
EMBO J.
, vol.16
, pp. 1291-1304
-
-
Wong, A.H.-T.1
Tam, N.W.N.2
Yang, Y.-L.3
Cuddihy, A.R.4
Li, S.5
Kirchoff, S.6
Hauser, H.7
Decker, T.8
Koromilas, A.E.9
-
41
-
-
0030449174
-
Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling
-
Zhang, J. J., U. Vinkemeier, W. Gu, D. Chakravarti, C. M. Horvath, and J. E. Darnell, Jr. 1996. Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc. Natl. Acad. Sci. USA 93:15092-15096.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15092-15096
-
-
Zhang, J.J.1
Vinkemeier, U.2
Gu, W.3
Chakravarti, D.4
Horvath, C.M.5
Darnell Jr., J.E.6
|