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Volumn 36, Issue 1, 1996, Pages 197-201

Structural organization of the human gene (PKR) encoding an interferon- inducible RNA-dependent protein kinase (PKR) and differences from its mouse homolog

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; PROTEIN KINASE;

EID: 0030586859     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0446     Document Type: Article
Times cited : (46)

References (35)
  • 1
    • 0027231434 scopus 로고
    • Translational regulation by the interferon-induced double-stranded RNA-activated 68-kDa protein kinase
    • 1. Barber, G. N., Wambach, M., Wong, M. L., Dever, T. E., Hinnebusch, A. G., and Katze, M. G. (1993). Translational regulation by the interferon-induced double-stranded RNA-activated 68-kDa protein kinase. Proc. Natl. Acad. Sci. USA 90: 4621-4625.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4621-4625
    • Barber, G.N.1    Wambach, M.2    Wong, M.L.3    Dever, T.E.4    Hinnebusch, A.G.5    Katze, M.G.6
  • 2
    • 0027294641 scopus 로고
    • Chromosomal assignment of the interferon-inducible double-stranded RNA-dependent protein kinase (PRKR) to human chromosome 2p21-p22 and mouse chromosome 17E2
    • 2. Barber, G. N., Edelhoff, S., Katze, M. G., and Disteche, C. M. (1993). Chromosomal assignment of the interferon-inducible double-stranded RNA-dependent protein kinase (PRKR) to human chromosome 2p21-p22 and mouse chromosome 17E2. Genomics 16: 765-767.
    • (1993) Genomics , vol.16 , pp. 765-767
    • Barber, G.N.1    Edelhoff, S.2    Katze, M.G.3    Disteche, C.M.4
  • 3
    • 0022244511 scopus 로고
    • Mechanism of interferon action: Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon-treated mouse fibroblasts
    • 3. Berry, M. J., Knutson, G. S., Lasky, S. R., Munemitsu, S. M., and Samuel, C. E. (1985). Mechanism of interferon action: Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon-treated mouse fibroblasts. J. Biol. Chem. 260: 11240-11247.
    • (1985) J. Biol. Chem. , vol.260 , pp. 11240-11247
    • Berry, M.J.1    Knutson, G.S.2    Lasky, S.R.3    Munemitsu, S.M.4    Samuel, C.E.5
  • 4
    • 0022366770 scopus 로고
    • Transcription termination and 3′ processing: The end is in site
    • 4. Birnsteil, M. L., Busslinger, M., and Strub, K. (1985). Transcription termination and 3′ processing: The end is in site. Cell 41: 349-359.
    • (1985) Cell , vol.41 , pp. 349-359
    • Birnsteil, M.L.1    Busslinger, M.2    Strub, K.3
  • 5
    • 0002758687 scopus 로고
    • Marathon cDNA amplification: A new method for cloning full-length cDNAs
    • 5. Chenchik, A., Moqadam, F., and Siebert, P. (1995). Marathon cDNA amplification: A new method for cloning full-length cDNAs. CLONTECHniques X: 5-8.
    • (1995) CLONTECHniques , vol.10 , pp. 5-8
    • Chenchik, A.1    Moqadam, F.2    Siebert, P.3
  • 6
    • 0002352428 scopus 로고    scopus 로고
    • Protein kinases that phosphorylate eIF-2 and eIF-2B, and their role in eukaryotic cell translational control
    • Cold Spring Harbor Press, Cold Spring Harbor, NY
    • 6. Clemens, M. J. (1996). Protein kinases that phosphorylate eIF-2 and eIF-2B, and their role in eukaryotic cell translational control. In "Translational Control," pp. 139-172, Cold Spring Harbor Press, Cold Spring Harbor, NY.
    • (1996) Translational Control , pp. 139-172
    • Clemens, M.J.1
  • 8
    • 0030198564 scopus 로고    scopus 로고
    • Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase
    • 8. George, C. X., Thomis, D. C., McCormack, S. J., Svahn, C. M., and Samuel, C. E. (1996). Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase. Virology 221: 180-188.
    • (1996) Virology , vol.221 , pp. 180-188
    • George, C.X.1    Thomis, D.C.2    McCormack, S.J.3    Svahn, C.M.4    Samuel, C.E.5
  • 9
    • 0025832056 scopus 로고
    • Translational control in mammalian cells
    • 9. Hershey, J. W. B. (1991). Translational control in mammalian cells. Annu. Rev. Biochem. 60: 715-755.
    • (1991) Annu. Rev. Biochem. , vol.60 , pp. 715-755
    • Hershey, J.W.B.1
  • 10
    • 0025999848 scopus 로고
    • TIK, a novel serine/threonine kinase, is recognized by antibodies directed against phosphotyrosine
    • 10. Icely, P. L., Gros, P., Bergeron, J. J. M., Devalult, A., Afar, D. E. H., and Bell, J. C. (1991). TIK, a novel serine/threonine kinase, is recognized by antibodies directed against phosphotyrosine. J. Biol. Chem. 266: 16073-16077.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16073-16077
    • Icely, P.L.1    Gros, P.2    Bergeron, J.J.M.3    Devalult, A.4    Afar, D.E.H.5    Bell, J.C.6
  • 12
    • 0027949937 scopus 로고
    • The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins
    • 12. Lee, T. G., Tang, N., Thompson, S., Miller, J., and Katze, M. G. (1994). The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins. Mol. Cell. Biol. 14: 2331-2342.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2331-2342
    • Lee, T.G.1    Tang, N.2    Thompson, S.3    Miller, J.4    Katze, M.G.5
  • 13
    • 0027178076 scopus 로고
    • Tumor-suppressor genes: News about the interferon connection
    • 13. Lengyel, P. (1993). Tumor-suppressor genes: News about the interferon connection. Proc. Natl. Acad. Sci. USA 90: 5893-5895.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5893-5895
    • Lengyel, P.1
  • 14
    • 0029586334 scopus 로고
    • Intron phase correlations and the evolution of the intron/exon structure of genes
    • 14. Long, M., Rosenberg, C., and Gilbert, W. (1995). Intron phase correlations and the evolution of the intron/exon structure of genes. Proc. Natl. Acad. Sci. USA 92: 12495-12499.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12495-12499
    • Long, M.1    Rosenberg, C.2    Gilbert, W.3
  • 16
    • 0000519248 scopus 로고
    • Viral evasion of cellular defense mechanisms: Regulation of the protein kinase DAI by RNA effectors
    • 16. Mathews, M. B. (1993). Viral evasion of cellular defense mechanisms: Regulation of the protein kinase DAI by RNA effectors. Semin. Virol. 4: 247-257.
    • (1993) Semin. Virol. , vol.4 , pp. 247-257
    • Mathews, M.B.1
  • 17
    • 0026716255 scopus 로고
    • Mechanism of interferon action: Identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1.EIF-2α protein kinase
    • 17. McCormack, S. J., Thomis, D. C., and Samuel, C. E. (1992). Mechanism of interferon action: Identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1.eIF-2α protein kinase. Virology 188: 47-56.
    • (1992) Virology , vol.188 , pp. 47-56
    • McCormack, S.J.1    Thomis, D.C.2    Samuel, C.E.3
  • 18
    • 0025298202 scopus 로고
    • Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
    • 18. Meurs, E., Chong, K., Galabru, J., Thomas, N. S. B., Kerr, I. M., Williams, B. R. G., and Hovanessian, A. G. (1990). Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell 62: 232-236.
    • (1990) Cell , vol.62 , pp. 232-236
    • Meurs, E.1    Chong, K.2    Galabru, J.3    Thomas, N.S.B.4    Kerr, I.M.5    Williams, B.R.G.6    Hovanessian, A.G.7
  • 19
    • 0030030724 scopus 로고    scopus 로고
    • Mechanism of interferon action: Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells
    • 19. Ortega, L. G., McCotter, M. D., Henry, G. L., McCormack, S. J., and Samuel, C. E. (1996). Mechanism of interferon action: Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells. Virology 215: 31-39.
    • (1996) Virology , vol.215 , pp. 31-39
    • Ortega, L.G.1    McCotter, M.D.2    Henry, G.L.3    McCormack, S.J.4    Samuel, C.E.5
  • 21
    • 0028241859 scopus 로고
    • Role of the amino-terminal residues of the interferon-induced protein kinase and its activation by double-stranded RNA and heparin
    • 21. Patel, R. C., Stanton, P., and Sen, G. C. (1994). Role of the amino-terminal residues of the interferon-induced protein kinase and its activation by double-stranded RNA and heparin. J. Biol. Chem. 269: 18593-18598.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18593-18598
    • Patel, R.C.1    Stanton, P.2    Sen, G.C.3
  • 22
    • 0029115903 scopus 로고
    • The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo
    • 22. Patel, R. C., Stanton, P., McMillan, N. M. J., Williams, B. R. G., and Sen, G. C. (1995). The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo. Proc. Natl. Acad. Sci. USA 92: 8283-8287.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8283-8287
    • Patel, R.C.1    Stanton, P.2    McMillan, N.M.J.3    Williams, B.R.G.4    Sen, G.C.5
  • 24
    • 0040350202 scopus 로고
    • Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated protein kinase possessing site-specificity similar to hemin-regulated rabbit reticulocyte kinase
    • 24. Samuel, C. E. (1979). Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated protein kinase possessing site-specificity similar to hemin-regulated rabbit reticulocyte kinase. Proc. Natl. Acad. Sci. USA 76: 600-604.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 600-604
    • Samuel, C.E.1
  • 25
    • 0025739093 scopus 로고
    • Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities
    • 25. Samuel, C. E. (1991). Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 183: 1-11.
    • (1991) Virology , vol.183 , pp. 1-11
    • Samuel, C.E.1
  • 26
    • 0027418321 scopus 로고
    • The eIF-2α protein kinases, regulators of translation in eukaryotes from yeasts to humans
    • 26. Samuel, C. E. (1993). The eIF-2α protein kinases, regulators of translation in eukaryotes from yeasts to humans. J. Biol. Chem. 268: 7603-7606.
    • (1993) J. Biol. Chem. , vol.268 , pp. 7603-7606
    • Samuel, C.E.1
  • 27
    • 0027026168 scopus 로고
    • Transcriptional regulation and transpositional selection of active SINE sequences
    • 27. Schmid, C., and Maraia, R. (1992). Transcriptional regulation and transpositional selection of active SINE sequences. Curr. Opin. Genet. Dev. 2: 874-882.
    • (1992) Curr. Opin. Genet. Dev. , vol.2 , pp. 874-882
    • Schmid, C.1    Maraia, R.2
  • 29
    • 0027285719 scopus 로고
    • Localization of the human interferon-induced, ds-RNA activated p68 kinase gene (PRKR) to chromosome 2p21-p22
    • 29. Squire, J., Meurs, E. G., Chong, K. L., McMillan, N. A. J., Hovanessian, A. G., and Williams, B. R. G. (1993). Localization of the human interferon-induced, ds-RNA activated p68 kinase gene (PRKR) to chromosome 2p21-p22. Genomics 16:768-770.
    • (1993) Genomics , vol.16 , pp. 768-770
    • Squire, J.1    Meurs, E.G.2    Chong, K.L.3    McMillan, N.A.J.4    Hovanessian, A.G.5    Williams, B.R.G.6
  • 30
    • 0027999025 scopus 로고
    • Mechanism of interferon action: Structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase
    • 30. Tanaka, H., and Samuel, C. E. (1994). Mechanism of interferon action: Structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase. Proc. Natl. Acad. Sci. USA 91: 7995-7999.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7995-7999
    • Tanaka, H.1    Samuel, C.E.2
  • 31
    • 0026716253 scopus 로고
    • Mechanism of interferon action: cDNA structure, expression and regulation of the interferon-induced, RNA-dependent P1/eIF-2α protein kinase from human cells
    • 31. Thomis, D. C., Doohan, J. P., and Samuel, C. E. (1992). Mechanism of interferon action: cDNA structure, expression and regulation of the interferon-induced, RNA-dependent P1/eIF-2α protein kinase from human cells. Virology 188: 33-46.
    • (1992) Virology , vol.188 , pp. 33-46
    • Thomis, D.C.1    Doohan, J.P.2    Samuel, C.E.3
  • 32
    • 0026442274 scopus 로고
    • Mechanism of interferon action: Autoregulation of RNA-dependent P1/eIF-2α protein kinase (PKR) expression in transfected mammalian cells
    • 32. Thomis, D. C., and Samuel, C. E. (1992). Mechanism of interferon action: Autoregulation of RNA-dependent P1/eIF-2α protein kinase (PKR) expression in transfected mammalian cells. Proc. Natl. Acad. Sci. USA 89: 10837-10841.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10837-10841
    • Thomis, D.C.1    Samuel, C.E.2
  • 33
    • 0027420488 scopus 로고
    • Mechanism of interferon action: Evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR
    • 33. Thomis, D. C., and Samuel, C. E. (1993). Mechanism of interferon action: Evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR. J. Virol. 67: 7695-7700.
    • (1993) J. Virol. , vol.67 , pp. 7695-7700
    • Thomis, D.C.1    Samuel, C.E.2
  • 34
    • 0028942724 scopus 로고
    • Rapid physical mapping of the human trk proto-oncogene (NTRK1) gene to human chromosome 1q21-22 by P1 clone selection, fluorescence in situ hybridization (FISH) and computer-assisted microscopy
    • 34. Weier, H. U. G., Rhein, A. P., Shadravan, F., Collins, C., Polikoff, D. (1995). Rapid physical mapping of the human trk proto-oncogene (NTRK1) gene to human chromosome 1q21-22 by P1 clone selection, fluorescence in situ hybridization (FISH) and computer-assisted microscopy. Genomics 26: 390-393.
    • (1995) Genomics , vol.26 , pp. 390-393
    • Weier, H.U.G.1    Rhein, A.P.2    Shadravan, F.3    Collins, C.4    Polikoff, D.5
  • 35
    • 0028895186 scopus 로고
    • The interferon-inducible, double-stranded RNA-specific adenosine deaminase gene (DSRAD) maps to human chromosome 1q21.1-21.2
    • 35. Weier, H-U. G., George, C. X., Greulich, K. M., and Samuel, C. E. (1995). The interferon-inducible, double-stranded RNA-specific adenosine deaminase gene (DSRAD) maps to human chromosome 1q21.1-21.2. Genomics 30: 372-375.
    • (1995) Genomics , vol.30 , pp. 372-375
    • Weier, H.-U.G.1    George, C.X.2    Greulich, K.M.3    Samuel, C.E.4


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