Mutators in Escherichia coli

Mutation Research - DNA Repair

Volumn 409, Issue 3, 1998, Pages 99-106

  Miller, Jeffrey H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cancer; DNA repair; Episolon; Mismatch repair; Mutation; Mutators; Oxidative damage; Pathogenicity

Indexed keywords

MUTAGENIC AGENT;

CANCER; DNA DAMAGE; DNA REPAIR; GENE MUTATION; HUMAN; MUTAGENESIS; MUTATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW;

ESCHERICHIA COLI;

EID: 0031797448     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(98)00049-4     Document Type: Article

References (87)

1. Drake J.W. Spontaneous mutation. Annu. Rev. Genet. 25:1991;125-146.
2. E.C. Friedberg, G.C. Walker, W. Seide, DNA Repair and Mutagenesis, Am. Soc. Microbiol., Washington, DC, 1995.
3. Modrich P. Mechanisms and biological effects of mismatch repair. Annu. Rev. Genet. 25:1991;229-253.
4. Smith K.C. Spontaneous mutagenesis: experimental, genetic, and other factors. Mutat. Res. 277:1992;139-162.
5. Miller J.H. Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair. Annu. Rev. Microbiol. 50:1996;625-643.
6. Plough H.H. Spontaneous mutability in Drosophila. Cold Spring Harbor Symp. Quant. Biol. 9:1941;127-137.
7. Treffers H.P., Spinelli V., Belser N.O. A factor (or mutator gene) influencing mutation rates in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 40:1954;1064-1071.
8. W.D. Rupp, DNA repair mechanisms, in: F.C. Neidhardt (Ed.), Escherichia coli and Salmonella typhimurium, Cellular and Molecular Biology, Am. Soc. Microbiol, 2nd edn., Washington, DC, 1987, pp. 2277-2294.
9. Nghiem Y., Cabrera M., Cupples C.G., Miller J.H. The mutY gene: a mutator locus in Escherichia coli that generates GC→TA transversions. Proc. Natl. Acad. Sci. U.S.A. 85:1988;2709-2713.
10. Michaels M.L., Cruz C., Grollman A.P., Miller J.H. Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA. Proc. Natl. Acad. Sci. U.S.A. 89:1992;7022-7025.
11. Cabrera M., Nghiem Y., Miller J.H. mutM, a second mutator locus in Escherichia coli that generates GC→TA transversions. J. Bacteriol. 170:1988;5405-5407.
12. Boiteux S., O'Connor T.R., Laval J. Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and over-production of the protein. EMBO Journal. 6:1987;3177-3183.
13. Michaels M.L., Pham L., Cruz C., Miller J.H. MutM, a protein that prevents G:C→T:A transversions, if formamidopyrimidine-DNA glycosylase. Nucleic Acids Res. 19:1991;3629-3632.
14. Yanofsky C., Cox E.C., Horn V. The unusual mutagenic specificity of an E. coli mutator gene. Proc. Natl. Acad. Sci. U.S.A. 55:1966;274-281.
15. Maki H., Sekiguchi M. MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis. Nature. 355:1992;273-275.
16. Farr S.B., D'ari R., Touati D. Oxygen-dependent mutagenesis in Escherichia coli lacking superoxide dismutase. Proc. Natl. Acad. Sci. U.S.A. 83:1986;8268-8272.
17. Storz G., Christman M.F., Sies H., Ames B.N. Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium. Proc. Natl. Acad. Sci. U.S.A. 84:1987;8917-8921.
18. Jiang D., Hatahet Z., Blaisdell J.O., Melamede R.J., Wallace S.S. Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutants. J. Bacteriol. 179:1997;3773-3782.
19. Duncan B., Miller J.H. On the mutagenic deamination of cystosine residues in DNA. Nature. 287:1980;560-561.
20. Kunz B.A., Henson E.S., Roche H., Ramotar D., Nunoshiba T., Demple B. Specificity of the mutator caused by deletion of the yeast structural gene (APNI) for the major apurinic endonuclease. Proc. Natl. Acad. Sci. U.S.A. 91:1994;8165-8169.
21. Lieb M., Bhagwat A.S. Very short patch repair: reducing the cost of cytosine methylation. Mol. Microbiol. 20:1996;467-473.
22. Macintyre G., Doiron K.M., Cupples C.G. The Vsr endonuclease of Escherichia coli: an efficient DNA repair enzyme and a potent mutagen. J. Bacteriol. 179:1997;6048-6052.
23. Mackay W.J., Han S., Samson L.D. DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coli. J. Bacteriol. 176:1994;3224-3230.
24. Samson L. The suicidal DNA repair methyltransferases of microbes. Mol. Gen. Microbiol. 6:1992;825-831.
25. Glickman B.W. Spontaneous mutagenesis in Escherichia coli strains lacking 6-methyladenine residues in their DNA: an altered mutational spectrum in dam-mutants. Mutat. Res. 61:1979;153-162.
26. Cox E.C. Bacterial mutator genes and the control of spontaneous mutation. Annu. Rev. Genet. 10:1976;135-156.
27. Cupples C.G., Cabrera M., Cruz C., Miller J.H. A set of lacZ mutations in Escherichia coli that allow rapid detection of specific frameshift mutations. Genetics. 125:1990;275-280.
28. Leong P.-M., Hsia H.C., Miller J.H. Analysis of spontaneous base substitutions generated in mismatch-repair-deficient strains of Escherichia coli. J. Bacteriol. 168:1986;412-416.
29. Schaaper R.M., Dunn R.L. Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors. Proc. Natl. Acad. Sci. U.S.A. 84:1987;6220-6224.
30. Modrich P. Methyl-directed DNA mismatch correction. J. Biol. Chem. 264:1989;6597-6600.
31. Cox E.C., Horner D.L. Dominant mutators in Escherichia coli. Genetics. 100:1982;7-18.
32. Cox E.C., Horner D.L. Structure and coding properties of a dominant Escherichia coli mutator gene, mutD. Proc. Natl. Acad. Sci. U.S.A. 80:1983;2295-2299.
33. Echols H., Lu C., Burgers P.M.J. Mutator strains of Eschericha coli, mutD5, and dnaQ, with defective exonucleolytic editing by DNA polymerase III holoenzyme. Proc. Natl. Acad. Sci. U.S.A. 80:1983;2189-2192.
34. Coukell M.B., Yanofsky C. Increased frequency of deletions in DNA polymerase mutants of Escherichia coli. Nature. 228:1970;633-635.
35. Vaccaro K.K., Siegel E.C. Increased spontaneous reversion of certain frameshift mutations in DNA polymerase I deficient strains of Escherichia coli. Mol. Gen. Genet. 141:1975;251-262.
36. Fowler R.G., Schaaper R.M. The role of the mutT gene of Escherichia coli in maintaining replication fidelity. FEMS Microbiol. Rev. 21:1997;43-54.
37. Foster P.L., Trimarchi J.M., Maurer R.A. Two enzymes, both of which process recombination intermediates, have opposite effects on adaptive mutation in Escherichia coli. Genetics. 142:1996;25-37.
38. Harris R.S., Ross K.J., Rosenberg S.M. Opposing roles of the holiday junction processing systems of Escherichia coli in recombination-dependent adaptive mutation. Genetics. 142:1996;681-691.
39. Whoriskey S.K., Schofield M.A., Miller J.H. Isolation and characterization of Escherichia coli mutants with altered rates of deletion formation. Genetics. 127:1991;21-30.
40. Schofield M.A., Agbunag R., Michaels M.L., Miller J.H. Cloning and sequencing of Escherichia coli mutR shows it identity to topB, encoding topoisomerase III. J. Bacteriol. 174:1992;5168-5170.
41. Lejeune P., Danchin A. Mutations in the bglY gene increase the frequency of spontaneous deletions in Escherichia coli K-12. Proc. Natl. Acad. Sci. U.S.A. 87:1990;360-363.
42. M.M. Slupska, J.-H. Chiang, W.M. Luther, J.J. Lee, L. Amii, J.H. Miller, Genes involved in the determination of the rate of inversions at short inverted repeats, Mol. Micro. Gen., submitted.
43. Allgood N.D., Silhavy T.J. Escherichia coli xonA (sbcB) mutants enhance illegitimate recombination. Genetics. 127:1991;671-680.
44. Connelly J.C., Leach D.R.F. The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination. Genes to Cells. 1:1996;285-291.
45. Michaels M.L., Pham L., Cruz C., Miller J.H. mutA and mutC: two mutator loci in Escherichia coli that stimulate transversions. Proc. Natl. Acad. Sci. U.S.A. 87:1990;9211-9215.
46. Slupska M.S., Baikalov C., Lloyd R., Miller J.H. Mutator tRNAs are encoded by the Escherichia coli mutator genes mutA and mutC: a novel pathway for mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 93:1995;4380-4385.
47. Connolly D.M., Winkler M.E. Structure of Escherichia coli K-12 miaA and characterization of the mutator phenotype caused by miaA insertion mutations. J. Bacteriol. 173:1991;1711-1721.
48. Grilley M., Griffith J., Modrich P. Bidirectional excision in methyl-directed mismatch repair. J. Biol. Chem. 268:1993;11830-11837.
49. Nevers P., Spatz H. Escherichia coli mutants uvrD uvrE deficient in gene conversion of lambda heteroduplexes. Mol. Gen. Genet. 139:1975;233-243.
50. Rydberg B. Bromouracil mutagenesis and mismatch repair in Escherichia coli. Mutat. Res. 52:1978;11-24.
51. Nghiem Y., Cabrera M., Cupples C.G., Miller J.H. The mutY gene: a mutator locus in Escherichia coli that generates GC→TA transversions. Proc. Natl. Acad. Sci. U.S.A. 85:1988;2709-2713.
52. Au K.G., Clark S., Miller J.H., Modrich P. The Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs. Proc. Natl. Acad. Sci. U.S.A. 86:1989;8877-8881.
53. Michaels M.L., Miller J.H. The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8 dihydro-8-oxoguanine). J. Bacteriol. 174:1992;6321-6325.
54. Shibutani S., Takeshita M., Grollman A.P. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature. 349:1991;431-434.
55. Demple B. Regulation of bacterial oxidative stress genes. Annu. Rev. Genet. 25:1991;315-337.
56. Storz G., Christman M.F., Sies H., Ames B.N. Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium. Proc. Natl. Acad. Sci. U.S.A. 84:1987;8917-8921.
57. Lindahl T. Instability and decay of the primary structure of DNA. Nature. 362:1994;709-715.
58. M.M. Slupska, A.G. King, L.I. Lu, R.H. Lin, E.F. Mao, C.A. Lackey, J. Chiang, C. Baikalov, J.H. Miller, Examination of the role of DNA polymerase proofreading in the mutator effect of miscoding tRNAs, J. Bacteriol., in press.
59. J.E. Cleaver, K.H. Kraemer, Xeroderma pigmentosum, In: C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle (Eds.), The Metabolic Basis of Inherited Disease, 6th edn., McGraw-Hill, New York, 1989, pp. 2949-2971.
60. Yu C.E., Oshima J., Fu Y.H., Wijsman E.M., Hisama F., Alisch R., Matthews S., Nakura J., Miki T., Ouais S., Martin G.M., Mulligan J., Schellenberg G.D. Positional cloning of the Werner's syndrome gene. Science. 272:1996;262-285.
61. Gray M.D., Shen J.-C., Kamath-Loeb A.S., Blank A., Sopher B.L., Martin G.M., Oshima J., Loeb L.A. The Werner syndrome protein is a DNA helicase. Nature Gen. 17:1997;100-103.
62. Lyons T.J., Liu H., Goto J.J., Nersissian A., Roe J.A., Graden J.A., Cafe C., Ellerby L.M., Bredesen D.E., Gralla E.B., Valentine J.S. Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein. Proc. Natl. Acad. Sci. U.S.A. 93:1996;12240-12244.
63. m for hydrogen peroxide. Proc. Natl. Acad. Sci. U.S.A. 93:1996;5709-5714.
64. Modrich P. Mechanisms and biological effects of mismatch repair. Annu. Rev. Genet. 25:1991;229-253.
65. Fishel R., Lescoe M.K., Rao M.R.S., Copeland N.G., Jenkins N.A., Garber J., Kane M., Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell. 75:1993;1027-1038.
66. Leach F.S., Nicolaides N.C., Papadopoulos N., Liu B., Jen J., Parsons R., Peltomäki P., Sistonen P., Aaltonen L.A., Nyström-Lahti M.et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell. 75:1993;1215-1225.
67. Papadopoulos N., Nicolaides N.C., Wei Y.F., Ruben S.M., Carter K.C., Rosen C.A., Haseltine W.A., Fleischmann R.D., Fraser C.M., Adams et al M.D. Mutation of a mutL homolog in hereditary nonpolyposis colon cancer. Science. 263:1994;1625-1629.
68. Strand M., Prolla T.A., Liskay R.M., Petes T.D. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature. 365:1993;274-276.
69. Nowell P.C. The clonal evolution of tumor cell populations. Science. 194:1976;23-28.
70. Loeb L.A. Mutator phenotype may be required for multistage carcinogenesis. Cancer Res. 51:1991;3075-3079.
71. Degnen G.E., Cox E.C. A conditional mutator gene in Escherichia coli: isolation, mapping and effector studies. J. Bacteriol. 17:1974;477-487.
72. Helling R.B. Selection of a mutant of Escherichia coli which has high mutation rates. J. Bacteriol. 96:1968;975-980.
73. Hoess R.H., Herman R.K. Isolation and characterization of mutator strains of Escherichia coli K-12. J. Bacteriol. 122:1975;474-484.
74. Liberfarb R.M., Bryson V. Isolation, characterization and genetic analysis of mutator genes in Escherichia coli B and K-12. J. Bacteriol. 104:1970;363-375.
75. Chao L., Cox E.C. Competition between high and low mutating strains of Escherichia coli. Evolution. 37:1983;125-134.
76. Cox E.C., Gibson T.C. Selection for high mutation rates in chemostats. Genetics. 77:1974;169-184.
77. Gibson T.C., Scheppe M.L., Cox E.C. Fitness of an Escherichia coli mutator gene. Science. 169:1970;686-688.
78. Nestman E.R., Hill R.F. Population changes in continuously growing mutator cultures of Escherichia coli. Genetics. 73:1973;41-44. Suppl.
79. Siegel E.C., Bryson B. Mutator gene of Escherichia coli B. J. Bacteriol. 94:1967;38-47.
80. Mao E.F., Lane L., Lee J., Miller J.H. Proliferation of mutators in a cell population. J. Bacteriol. 179:1997;417-422.
81. Sniegowski P.D., Gerrish P.J., Lenski R.E. Evolution of high mutation rates in experimental populations of E. coli. Nature. 387:1997;703-705.
82. J.H. Miller, A. Suthar, J. Tai, A. Yeung, C. Truong, J. Lee, Direct selection for mutators in Escherichia coli, J. Bacteriol., in press.
83. Gross M.D., Siegel E.C. Incidence of mutator strains in Escherichia coli and coliforms in nature. Mutat. Res. 91:1981;107-110.
84. Jyssum K. Observations on two types of genetic instability in Escherichia coli. Acta Pathol. Microbiol. Scand. 48:1960;113-120.
85. LeClerc J.E., Li B., Payne W.L., Cebula T.A. High mutation frequencies among Escherichia coli and Salmonella pathogens. Science. 274:1996;1208-1211.
86. Rayssiguier C., Thaler D.S., Radman M. The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature. 342:1989;396-401.
87. Matic I., Radman M., Taddei F., Picard B., Doit C., Bingen E., Denamur E., Elion J. Highly variable mutation rates in commensal and pathogenic Escherichia coli. Science. 277:1997;1833-1834.