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Volumn 6, Issue 2-3, 1998, Pages 217-224

Integrin Signaling: Cytoskeletal Complexes, MAP Kinase Activation, and Regulation of Gene Expression

Author keywords

Cell adhesion; Extracellular matrix; Fibronectin; Integrin; Signal transduction

Indexed keywords

INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; SCLEROPROTEIN;

EID: 0031796751     PISSN: 10615385     EISSN: None     Source Type: Journal    
DOI: 10.3109/15419069809004477     Document Type: Article
Times cited : (57)

References (46)
  • 1
    • 0027230170 scopus 로고
    • Regulation of development and differentiation by the extracellular matrix
    • Adams, J.C. and Watt, F.M. (1993) Regulation of development and differentiation by the extracellular matrix. Development 117, 1183-1198.
    • (1993) Development , vol.117 , pp. 1183-1198
    • Adams, J.C.1    Watt, F.M.2
  • 2
    • 0028343192 scopus 로고
    • Transmembrane signal transduction by integrin cytoplasmic domains expressed in single-subunit chimeras
    • Akiyama, S.K., Yamada, S.S., Yamada, K.M. and LaFlamme, S.E. (1994) Transmembrane signal transduction by integrin cytoplasmic domains expressed in single-subunit chimeras. J. Biol. Chem. 269, 15961-15964.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15961-15964
    • Akiyama, S.K.1    Yamada, S.S.2    Yamada, K.M.3    Laflamme, S.E.4
  • 3
    • 0031050451 scopus 로고    scopus 로고
    • Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression
    • Assoian, R.K and Zhu, X. (1997) Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression. Curr. Opin. Cell Biol. 9, 93-98.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 93-98
    • Assoian, R.K.1    Zhu, X.2
  • 5
    • 0027939187 scopus 로고
    • Integrin mediated cell adhesion activates mitogen-activated protein kinases
    • Chen, Q., Kinch, M.S., Lin, T.H., Burridge, K. and Juliano, R.L. (1994) Integrin mediated cell adhesion activates mitogen-activated protein kinases. J. Biol. Chem. 269, 26602-26605.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26602-26605
    • Chen, Q.1    Kinch, M.S.2    Lin, T.H.3    Burridge, K.4    Juliano, R.L.5
  • 7
    • 0028987936 scopus 로고
    • Integrins and signal transduction pathways: The road taken
    • Clark, E A. and Brugge, J.S (1995) Integrins and signal transduction pathways: the road taken. Science 268, 233-239.
    • (1995) Science , vol.268 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 8
    • 0028237280 scopus 로고
    • Extracellular matrix modulates epidermal growth factor receptor activation in rat glomerular epithelial cells
    • Cybulsky, A.V., McTavish, A.J. and Cyr, M D. (1994) Extracellular matrix modulates epidermal growth factor receptor activation in rat glomerular epithelial cells. J. Clin. Invest 94, 68-76.
    • (1994) J. Clin. Invest , vol.94 , pp. 68-76
    • Cybulsky, A.V.1    McTavish, A.J.2    Cyr, M.D.3
  • 9
    • 0031257749 scopus 로고    scopus 로고
    • Focal adhesion kmase in integrin signaling
    • Guan, J (1997) Focal adhesion kmase in integrin signaling. Matrix Biol. 16, 195-200.
    • (1997) Matrix Biol. , vol.16 , pp. 195-200
    • Guan, J.1
  • 10
    • 0022671903 scopus 로고
    • Interaction of fibronectin-coated beads with attached and spread fibroblasts: Binding. phagocytosis, and cytoskeletal reorganization
    • Grinnell, F. and Geiger, B (1986) Interaction of fibronectin-coated beads with attached and spread fibroblasts: binding. phagocytosis, and cytoskeletal reorganization Exp. Cell Res. 162, 449-461.
    • (1986) Exp. Cell Res. , vol.162 , pp. 449-461
    • Grinnell, F.1    Geiger, B.2
  • 11
    • 0030056968 scopus 로고    scopus 로고
    • Cell adhesion: The molecular basis of tissue architecture and morphogenesis
    • Gumbiner, B.M. (1996) Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84, 345-357
    • (1996) Cell , vol.84 , pp. 345-357
    • Gumbiner, B.M.1
  • 12
    • 0022534722 scopus 로고
    • Interaction of plasma membrane fibronectin receptor with talin - A transmembrane linkage
    • Horwitz, A. Duggan, K., Buck, C. Beckerle, M.C. and Burridge, K (1986) Interaction of plasma membrane fibronectin receptor with talin - a transmembrane linkage. Nature 320, 531-533.
    • (1986) Nature , vol.320 , pp. 531-533
    • Horwitz, A.1    Duggan, K.2    Buck, C.3    Beckerle, M.C.4    Burridge, K.5
  • 13
    • 0030933277 scopus 로고    scopus 로고
    • Oncoprotein networks
    • Hunter, T (1997) Oncoprotein networks. Cell 88, 333-346.
    • (1997) Cell , vol.88 , pp. 333-346
    • Hunter, T.1
  • 14
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes, R O. (1992) Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69, 11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 15
    • 0031044781 scopus 로고    scopus 로고
    • Focal adhesion kinase: At the crossroads of signal transduction
    • Ilic, D., Damsky, C.H. and Yamamoto, T. (1997) Focal adhesion kinase: at the crossroads of signal transduction. J. Cell Sci. 110, 401-407.
    • (1997) J. Cell Sci. , vol.110 , pp. 401-407
    • Ilic, D.1    Damsky, C.H.2    Yamamoto, T.3
  • 17
    • 0027459771 scopus 로고
    • Signal transduction from the extracellular matrix
    • Juhano, R.L. and Haskill, S. (1993) Signal transduction from the extracellular matrix. J. Cell Biol. 120, 577-585.
    • (1993) J. Cell Biol. , vol.120 , pp. 577-585
    • Juhano, R.L.1    Haskill, S.2
  • 18
    • 0025946283 scopus 로고
    • Signal transduction by integrins: Increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins
    • Kornberg, L.J., Earp, H.S., Turner, C.E., Prockop, C. and Juliano, R.L. (1991) Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins. Proc. Natl. Acad. Sci. USA 88, 8392-8396.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8392-8396
    • Kornberg, L.J.1    Earp, H.S.2    Turner, C.E.3    Prockop, C.4    Juliano, R.L.5
  • 19
    • 0027055575 scopus 로고
    • Cell adhesion or integrin clustering increases phosphorylation of focal adhesion-associated tyrosine kinase
    • Kornberg, L., Earp, H.S., Parsons, J.T., Schaller, M. and Juliano, R.L. (1992) Cell adhesion or integrin clustering increases phosphorylation of focal adhesion-associated tyrosine kinase. J. Biol. Chem. 267, 23439-23442.
    • (1992) J. Biol. Chem. , vol.267 , pp. 23439-23442
    • Kornberg, L.1    Earp, H.S.2    Parsons, J.T.3    Schaller, M.4    Juliano, R.L.5
  • 20
    • 0030582716 scopus 로고    scopus 로고
    • Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors
    • Koyama, H., Raines, E.W., Bornfeldt, K.E., Roberts, J.M. and Ross, R. (1996) Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors. Cell 87, 1069-1078.
    • (1996) Cell , vol.87 , pp. 1069-1078
    • Koyama, H.1    Raines, E.W.2    Bornfeldt, K.E.3    Roberts, J.M.4    Ross, R.5
  • 21
    • 0026535449 scopus 로고
    • Regulation of fibronectin receptor distribution
    • LaFlamme, S.E., Akiyama, S.K. and Yamada, K.M. (1992) Regulation of fibronectin receptor distribution. J. Cell Biol. 117, 437-447.
    • (1992) J. Cell Biol. , vol.117 , pp. 437-447
    • Laflamme, S.E.1    Akiyama, S.K.2    Yamada, K.M.3
  • 22
    • 0027994108 scopus 로고
    • Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading, and matrix assembly
    • LaFlamme, S.E., Thomas, L.A., Yamada, S.S. and Yamada, K M. (1994) Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading, and matrix assembly. J. Cell Biol. 126, 1287-1298.
    • (1994) J. Cell Biol. , vol.126 , pp. 1287-1298
    • Laflamme, S.E.1    Thomas, L.A.2    Yamada, S.S.3    Yamada, K.M.4
  • 23
    • 0031259319 scopus 로고    scopus 로고
    • Integrin cytoplasmic domains as connectors to the cell's signal transduction apparatus
    • LaFlamme, S.E., Homan, S.M., Bodeau, A.L. and Mastrangelo, A.M. (1997) Integrin cytoplasmic domains as connectors to the cell's signal transduction apparatus. Matrix Biol. 16, 153-163.
    • (1997) Matrix Biol. , vol.16 , pp. 153-163
    • Laflamme, S.E.1    Homan, S.M.2    Bodeau, A.L.3    Mastrangelo, A.M.4
  • 24
    • 0031937468 scopus 로고    scopus 로고
    • Adhesion to fibronectin or collagen I gel induces rapid, extensive, biosynthetic alterations in epithelial cells
    • Lafrenie, R.M., Bernier, S.M and Yamada, K M. (1998) Adhesion to fibronectin or collagen I gel induces rapid, extensive, biosynthetic alterations in epithelial cells. J. Cell Physiol. 175, 163-173
    • (1998) J. Cell Physiol. , vol.175 , pp. 163-173
    • Lafrenie, R.M.1    Bernier, S.M.2    Yamada, K.M.3
  • 25
    • 0029054284 scopus 로고
    • Mapping in vivo associations of cytoplasmic proteins with integrin beta I cytoplasmic domain mutants
    • Lewis, J.M. and Schwartz, M.A. (1995) Mapping in vivo associations of cytoplasmic proteins with integrin beta I cytoplasmic domain mutants Mol. Biol. Cell 6, 151-160.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 151-160
    • Lewis, J.M.1    Schwartz, M.A.2
  • 26
    • 0028238346 scopus 로고
    • Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed beta 1 integrin cytoplasmic domain
    • Lukashev, M.E., Sheppard, D. and Pytela, R. (1994) Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed beta 1 integrin cytoplasmic domain. J. Biol. Chem.269, 18311-18314.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18311-18314
    • Lukashev, M.E.1    Sheppard, D.2    Pytela, R.3
  • 27
    • 0028954797 scopus 로고
    • Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function
    • Miyamoto, S , Akiyama, S.K. and Yamada, K.M. (1995a) Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 267, 883-885.
    • (1995) Science , vol.267 , pp. 883-885
    • Miyamoto, S.1    Akiyama, S.K.2    Yamada, K.M.3
  • 29
    • 0030453194 scopus 로고    scopus 로고
    • Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors
    • Miyamoto, S., Teramoto, H., Gutkind, J S and Yamada, K.M. (1996) Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: Roles of integrin aggregation and occupancy of receptors. J. Cell Biol. 135, 1633-1642.
    • (1996) J. Cell Biol. , vol.135 , pp. 1633-1642
    • Miyamoto, S.1    Teramoto, H.2    Gutkind, J.S.3    Yamada, K.M.4
  • 31
    • 2742610561 scopus 로고
    • An interaction between α-actinin and the 81 integrin subunit in vitro
    • Otey, C.A. Pavalko, F.M. and Burridge, K. (1990) An interaction between α-actinin and the 81 integrin subunit in vitro. J. Cell Biol. 109, 3455-3464.
    • (1990) J. Cell Biol. , vol.109 , pp. 3455-3464
    • Otey, C.A.1    Pavalko, F.M.2    Burridge, K.3
  • 32
    • 0029965695 scopus 로고    scopus 로고
    • Integrin-mediated signalling: Regulation by protein tyrosine kinases and small GTP-binding proteins
    • Parsons, J.T. (1996) Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins. Curr. Opin. Cell Biol. 8, 146-152.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 146-152
    • Parsons, J.T.1
  • 33
    • 0028859279 scopus 로고
    • Protein modules and signalling networks
    • Pawson, T. (1995) Protein modules and signalling networks. Nature 373, 573-580.
    • (1995) Nature , vol.373 , pp. 573-580
    • Pawson, T.1
  • 34
    • 0028817908 scopus 로고
    • Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex
    • Plopper, G.E., McNamee, H.P., Dike, L.E., Bojanowski, K. and Ingber, D.E. (1995) Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex. Mol. Biol. Cell 6, 1349-1365.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 1349-1365
    • Plopper, G.E.1    McNamee, H.P.2    Dike, L.E.3    Bojanowski, K.4    Ingber, D.E.5
  • 35
    • 0029119564 scopus 로고
    • A hierarchy of ECM-mediated signaling regulates tissue-specific gene expression
    • Roskelly, C.D., Srebrow, A. and Bissell, M.J. (1995) A hierarchy of ECM-mediated signaling regulates tissue-specific gene expression. Curr. Opin. Cell Biol. 7, 736-747.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 736-747
    • Roskelly, C.D.1    Srebrow, A.2    Bissell, M.J.3
  • 36
    • 0028335948 scopus 로고
    • Anchorage dependence, integrins, and apoptosis
    • Ruoslahti, E. and Reed, J.C. (1994) Anchorage dependence, integrins, and apoptosis. Cell 77, 477-478.
    • (1994) Cell , vol.77 , pp. 477-478
    • Ruoslahti, E.1    Reed, J.C.2
  • 37
    • 0029150292 scopus 로고
    • Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains
    • Schaller, M.D., Otey, C.A., Hildebrand, J.D. and Parsons, J.T. (1995) Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains. J. Cell Biol. 130, 1181-1187.
    • (1995) J. Cell Biol. , vol.130 , pp. 1181-1187
    • Schaller, M.D.1    Otey, C.A.2    Hildebrand, J.D.3    Parsons, J.T.4
  • 38
    • 0028609382 scopus 로고
    • Integrin-mediated signal transduction linked to the ras pathway by GRB2 binding to focal adhesion kinase
    • Schlaepfer, D.D., Hanks, S.K., Hunter, T. and van der Geer, P. (1994) Integrin-mediated signal transduction linked to the ras pathway by GRB2 binding to focal adhesion kinase. Nature 372, 786-791.
    • (1994) Nature , vol.372 , pp. 786-791
    • Schlaepfer, D.D.1    Hanks, S.K.2    Hunter, T.3    Van der Geer, P.4
  • 40
    • 0030661566 scopus 로고    scopus 로고
    • Integrins, oncogenes, and anchorage independence
    • Schwartz, M.A. (1997) Integrins, oncogenes, and anchorage independence. J. Cell Biol. 139, 575-578.
    • (1997) J. Cell Biol. , vol.139 , pp. 575-578
    • Schwartz, M.A.1
  • 41
    • 0029670904 scopus 로고    scopus 로고
    • Stimulation of beta 1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors
    • Sundberg, C. and Rubin, K. (1996) Stimulation of beta 1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors. J. Cell Biol. 132, 741-752.
    • (1996) J. Cell Biol. , vol.132 , pp. 741-752
    • Sundberg, C.1    Rubin, K.2
  • 42
    • 0030584077 scopus 로고    scopus 로고
    • The adaptor protein She couples a class of integrins to the control of cell cycle progression
    • Wary, K.K., Maniero, F., Isakoff, S.J., Marcantonio, E.E. and Giancotti, F.G. (1996) The adaptor protein She couples a class of integrins to the control of cell cycle progression. Cell 87, 733-743.
    • (1996) Cell , vol.87 , pp. 733-743
    • Wary, K.K.1    Maniero, F.2    Isakoff, S.J.3    Marcantonio, E.E.4    Giancotti, F.G.5
  • 43
    • 0024335963 scopus 로고
    • Signal through the fibronectin receptor induces collagenase and stromelysin gene expression
    • Werb, Z., Tremble, P.M., Bchrcndtsen, O., Crowly, E. and Damsky, C.H. (1989) Signal through the fibronectin receptor induces collagenase and stromelysin gene expression. J. Cell Biol. 109, 877-889.
    • (1989) J. Cell Biol. , vol.109 , pp. 877-889
    • Werb, Z.1    Tremble, P.M.2    Bchrcndtsen, O.3    Crowly, E.4    Damsky, C.H.5
  • 44
    • 0031050449 scopus 로고    scopus 로고
    • Molecular interactions in cell adhesion complexes
    • Yamada, K.M. and Geiger, B. (1997) Molecular interactions in cell adhesion complexes. Curr. Opin. Cell Biol 9, 76-85.
    • (1997) Curr. Opin. Cell Biol , vol.9 , pp. 76-85
    • Yamada, K.M.1    Geiger, B.2
  • 45
    • 0029164237 scopus 로고
    • Integrin transmembrane signaling and cytoskeletal control
    • Yamada, K.M. and Miyamoto, S. (1995) Integrin transmembrane signaling and cytoskeletal control. Curr. Opin. Cell Biol. 7, 681-689.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 681-689
    • Yamada, K.M.1    Miyamoto, S.2
  • 46
    • 0028904784 scopus 로고
    • Integrin-dependent activation of MAP kinase: A link to shape-dependent cell proliferation
    • Zhu, X. and Assoian, R.K. (1995) Integrin-dependent activation of MAP kinase: A link to shape-dependent cell proliferation. Mol. Biol. Cell 6, 273-282.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 273-282
    • Zhu, X.1    Assoian, R.K.2


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