In utero allotransplantation of retrovirally transduced fetal hepatocytes in primates: Feasibility and short-term follow-Up

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 7, Issue 6, 1998, Pages 296-303

  Andreoletti, Marion ^a   LePercq, Jacques ^b   Loux, Nathalie ^a   Beaudoin, Sylvie ^b   Sacquin, Paul ^b   Borgnon, Joséphine ^a   Nguyen, Tuan ^a   Mahieu, Dominique ^b   Toubas, Françoise ^b   Di Rico, Virginie ^c   Farge, Denis ^a   Franco, Dominique ^c   Briand, Pascale ^a   Hamza, Jamil ^b   Capron, Frédérique ^c   Bargy, Frédéric ^b   Weber, Anne ^a,d  

^a INSERM   (France)

^b HÔPITAL SAINT VINCENT DE PAUL   (France)

^c HÔPITAL ANTOINE BÉCLÈRE   (France)

^d INSTITUT COCHIN   (France)

Author keywords

Allotransplantation; Fetal hepatocytes; In utero; Primates; Retroviral transduction

Indexed keywords

VIRUS VECTOR;

ALLOTRANSPLANTATION; ANIMAL EXPERIMENT; ARTICLE; CELL TRANSPLANTATION; FETUS; FETUS SURGERY; GENETIC TRANSDUCTION; LIVER DISEASE; LIVER TRANSPLANTATION; MACACA; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BETA-GALACTOSIDASE; CELL TRANSPLANTATION; CELLS, CULTURED; CRYOPRESERVATION; FETUS; GENE TRANSFER TECHNIQUES; GENETIC MARKERS; LIVER; LIVER TRANSPLANTATION; MACACA MULATTA; RETROVIRIDAE; TRANSPLANTATION, HOMOLOGOUS; UMBILICAL VEINS;

EID: 0031792251     PISSN: 14767058     EISSN: None     Source Type: Journal    
DOI: 10.3109/14767059809020462     Document Type: Article

References (25)

1. Flake AW, Harrison MR, and Zanjani ED: In utero stem cell transplantation. Exp Hematol 19:1061-1064, 1991.
2. Brown MS, Goldstein JL: A receptor mediated pathway for cholesterol homeostasis. Science 232:34-47, 1986.
3. Zanjani ED, Mackintosh FR, and Harrison MR: Hematopoietic chimerism in sheep and nonhuman primates by in utero transplantation of fetal hematopoietic stem cells. Blood Cells 17:349-363, 1991.
4. Harrison MR, Slotnick RN, Crombleholme TM, Golbus MS, Tarantal AF, Zanjani ED: In utero transplantation of fetal liver haematopoietic stem cells in monkeys. Lancet 2:1425-1427, 1989.
5. Touraine JL, Raudrant D, Royo C, Rebaud A, Barbier F, Roncarolo MG, Touraine F, Laplace S, Gebuhrer L, Bétuel H, Frappaz D, Freycon F, Vullo C: In utero transplantation of hemopoietic stem cells in humans. Transplantation Proceedings 23:1706-1708, 1991.
6. Touraine JL: Treatment of human fetuses and induction of immunological tolerance in humans by in utero transplantation of stem cells into fetal recipients. Acta Haematol 96:115-119, 1996.
7. Shields LE, Bryant EM, Easterling TR, Andrews RG: Fetal liver cell transplantation for the creation of lymphohematopoietic chimerism in fetal baboons. Am J Obstet Gynecol 173:1157-1160, 1995.
8. Zanjani ED, Flake AW, Rice H, Hedrick M, Tavassoli M: Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep. J Clin Invest 93:1051-1055, 1994.
9. Westgren M, Ek S, Bui T, Jansson B, Kjaeldgaard A, Markling L, Nennesmo I, Seiger A, Sarby B, Thornstrom S, Ringden O: Tissue distribution of transplanted fetal liver cells in the human fetal recipient. Am J Obstet Gynecol 176:49-53, 1997.
10. Gupta S, Yerneni PR, Vemuru RP, Lee CD, Yellin EL, Bhargawa KK: Studies on the safety of intrasplenic hepatocyte transplantation: Relevance to ex vivo gene therapy. Hum Gene Ther 4:249-257, 1993.
11. Gupta S, Vemuru RP, Lee CD, Yerneni PR, Aragona E, Burk RD: Hepatocytes exhibit superior transgene expression after transplantation into liver and spleen compared with peritoneal cavity or dorsal fat pad: Implications for hepatic gene therapy. Hum Gene Ther 5:959-967, 1994.
12. Koch KS, Brownlee GG, Goss SJ, Martinez-Conde A, Leffert HL: Retroviral vector infection and transplantation in rats of primary fetal rat hepatocytes. J Cell Sci 99:121-130, 1991.
13. Soriano HE, Gest AL, Bair DK, Vander Straten M, Lewis DE, Darlington GJ, Finegold MJ, Ledley FD: Feasibility of hepatocellular transplantation via the umbilical vein in prenatal and perinatal lambs. Fetal Diagn Ther 8:293-304, 1993.
14. Andreoletti M, Pages JC, Mahieu D, Loux N, Farge D, Sacquin P, Simon L, Hamza J, Bargy F, Briand P, Leperq J, Weber A: Preclinical studies for cell transplantation: Isolation of primate fetal hepatocytes, their cryopreservation, and efficient retroviral transduction. Hum Gene Ther 8:267-274, 1997.
15. Zanjani ED, Ascensao JL, Harrison MR, Tavassoli M: Ex vivo incubation with growth factors enhances the engrafment of fetal hematopoietic cells transplanted in sheep fetuses. Blood 79:3045-3049, 1992.
16. Riviere I, Brose K, Mulligan RC: Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells. Proc Natl Acad Sci USA 92:6733-6737, 1995.
17. Gilgenkrantz H, Duboc D, Juillard V, Couton D, Pavirani A, Guillet JG, Briand P, Kahn A: Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors: Role of the immune response. Hum Gene Ther 6:1265-1274, 1995.
18. Sun EL, Aspar DG, Ulrich RG, Melchior GW: Cryopreservation of cynomolgud monkey (Macaca fascicularis) hepatocytes for subsequent culture and protein synthesis studies. In Vitro Cell Dev Biol 25:147-150, 1990.
19. Bosch A, McCray PB, Chang SMW, Ulich TR, Simonet WS, Jolly DJ: Proliferation induced by keratinocyte growth factor enhances in vivo retroviral-mediated gene transfer to mouse hepatocytes. J Clin Invest 98:2683-2687, 1996.
20. Elwood NJ, Zogos H, Willson T, Begley CG: Retroviral transduction of human progenitor cells: Use of granulocyte colony-stimulating factor plus stem cell factor to mobilize progenitor cells in vivo and stimulation by Flt3/Klk-2 ligand in vitro. Blood 88:4452-4462, 1996.
21. Chesne C, Guyomard C, Fautrel A, Poullain MG, Fremond B, Jong HD, Guillouzo A: Viability and function in primary culture of adult hepatocytes from various animal species and human beings after cryopreservation. Hepatology 18:406-414, 1993.
22. Adams RM, Wang M, Crane AM, Brown B, Darlington GJ, Ledley FD: Effective cryopreservation and long-term storage of primary human hepatocytes with recovery of viability, differenciation, and replicative potential. Cell Transplantation 4:579-586, 1995.
23. Couffinhal T, Kearney M, Sullivan A, Silver M, Tsurumi Y, Isner JM: Histochemical staining following lacZ gene transfer underestimates transfection efficiency. Hum Gene Ther 8:929-934, 1997.
24. Petersen R, Kempler G, Barklis E: A stem cell-specific silencer in the primer-binding site of a retrovirus. Mol Cell Biol 11:1214-1221, 1991.
25. Kay MA, Baley P, Rothenberg S, Leland F, Fleming L, Ponder KP, Liu TJ, Finegold M, Darlington G, Pokorny W, Woo SLC: Expression of human al antitrypsin in dogs after autologous transplantation of retroviral transduced hepatocytes. Proc Natl Acad Sci USA 89:89-93, 1992.