Regulation of iron uptake minimizes iron-mediated oxidative stress

Journal of Biosciences

Volumn 23, Issue 4, 1998, Pages 483-489

  Braun, V ^a  

^a Mikrobiologie/Membranphysiologie   (Germany)

Author keywords

Iron overload; Iron regulation; Iron transport; Oxidative stress

Indexed keywords

HYDROGEN PEROXIDE; HYDROXIDE; IRON; OXYGEN RADICAL;

BACTERIAL METABOLISM; CELL PROTECTION; CONFERENCE PAPER; ESCHERICHIA COLI; HOMEOSTASIS; IRON KINETICS; IRON TRANSPORT; NONHUMAN; OXIDATIVE STRESS;

EID: 0031786972     PISSN: 02505991     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02936142     Document Type: Conference Paper

References (49)

1. 70-type factors that respond to extracytoplasmic stimuli; Mol Microbiol. 18 163-174
2. Angerer A M, Gaisser S and Braun V 1990 Nucleotide sequence of the sfuA, sfuB, and sfuC genes of Serratia marcescens suggest a periplasmic binding protein-dependent iron transport system; J. Bacteriol. 172 572-578
3. Beckman K B and Ames B N 1997 Oxidative decay of DNA; J. Biol. Chem. 272 19633-19636
4. Bishop L, Agbayani R, Ambudkar S V. Maloney P C and Ferro-Luzzi Ames G 1989 Reconstitution of a bacterial periplasmic permease in proteoliposomes and demonstration of ATP hydrolysis concomitant with transport; Proc. Natl. Acad. Sci. USA 86 6953-6957
5. Braun V 1997 Surface signaling: a novel transcription initiation mechanism starting from the cell surface; Arch. Microbiol. 167 325-331
6. Braun V and Hantke K 1997 Receptor-mediated bacterial iron transport; in Transition metals in microbial metabolism (eds) G Winkelmann and C J Carrano (Amsterdam: Harwood Academic Publishers) pp 81-116
7. Crosa J E 1997 Signal transduction and transcriptional and posttranscriptional control of iron-regulated genes in bacteria; Microbiol. Mol. Biol. Rev. 61 319-336
8. Davidson A L, Shuman H A and Nikaido H 1992 Mechanism of maltose transport in Escherichia coli: transmembrane signaling by periplasmic binding proteins; Proc. Natl. Acad. Sci. USA 89 2360-2364
9. Dean C R and Poole K 1993 Expression of the ferric enterobactin receptor (PfcA) of Pseudomonas aeruginosa: involvement of a two-component regulatory system; Mol. Microbiol. 8 1095-1103
10. Drechsel H and Winkelmann G 1997 Iron chelation and siderophores; in Transition metals in microbial metabolism (eds) G Winkelmann and C J Carrano (Amsterdam: Harwood Academic Publishers) pp 1-49
11. Earhart C F 1996 Uptake and metabolism of iron and molybdenum; in Escherichia coli and Salmonella (ed.) F C Neidhardt (Washington: ASM Press) pp 1075-1090
12. Enz S, Braun V and Crosa J H 1995 Transcription of the region encoding the ferric dicitrale-transport system in Escherichia coli. similarity between promoters for fecA and for extracytoplasmic function sigma factors; Gene 163 13-18
13. Path M J and Kolter R 1993 ABC transporters: bacterial exporters; Microbiol. Rev. 57 995-1017
14. Gaudu P, Moon N and Weiss B 1997 Regulation of the soxRS oxidative stress regulon. Reversible oxidation of the Fe-S centers of SoxR in vivo; J. Bio J. Chem. 272 5082-5086
15. Genco C A and Desai P J 1996 Iron acquisition in the pathogenic Neisseria; Trends Microbiol. 4 179-184
16. Ghigo J-M Letoffe S and Wandersman C 1997 A new type of hemophore-dependent heme acquisition system of Serratia marcescens reconstituted in Escherichia coli; J. Bacterial. 179 3572-3579
17. Gray-Owen S D and Schryvers A B 1996 Bacterial transferrin and lactoferrin receptors; Trends Microbiol. 4 185-191
18. Günter K and Braun V 1990 In vivo evidence for FhuA outer membrane receptor interaction with the TonB inner membrane protein of Escherichia coli; FEBS Lett. 274 85-88
19. Hantke K 1997 Ferrous iron transport by a magnesium transport system is toxic for Escherichia coli and Salmonella typhimurium; J. Bacteriol. 179 6201-6204
20. Härlc C, Kim I, Angerer A and Braun V 1995 Signal transfer through three compartments: transcription initiation of the Escherichia coli ferric citrate transport system from the cell surface; EMBO J. 14 1430-1438
21. Heinrichs D E and Poole K 1993 Cloning and sequence analysis of a gene (pchR) encoding an AraC family activator of pyochelin and ferripyochelin receptor synthesis in Pseudomonas aeruginosa; J. Bacterial. 175 5882-5889
22. Henle E S and Linn S 1997 Formation, prevention, and repair of DNA damage by iron/hydrogen peroxide; J. Biol. Chem. 272 19095-19089
23. Hidalgo E, Ding H and Demplc B 1997 Redox signal transduction via iron-sulfur clusters in the SoxR transcription activator; Trends Biochem. Sci. 22 207-210
24. Jiang X, Payne M A, Cao Z, Foster S B, Feix J B, Newton S M C and Klebba P E 1997 Ligand-specific opening of a gated-porin channel in the outer membrane of living bacteria; Science 276 1261-1264
25. Kammler M, Schön C and Hantke K 1993 Characterization of the ferrous iron uptake system of Escherichia coli; J. Bacterial. 175 6212-6219
26. Killmann H, Benz R and Braun V 1993 Conversion of the FhuA transport protein into a diffusion channel through the outer membrane of Escherichia coli; EMBO J. 12 3007-3016
27. Kim I, Stiefel A, Plantor S, Angerer A and Braun V 1997 Transcription induction of the ferric citrate transport genes via the N-terminus of the FecA outer membrane protein, the Ton system and the electrochemical potential of the cytoplasmic membrane; Mol. Microbiol 23 333-344
28. Koster M, van Klompenburg W, Bitter W and Weisbeek P 1994 Role for the outer membrane ferric-siderophore receptor PupB in signal transduction across the bacterial cell envelope; EMBO J. 13 2805-2813
29. Köster W and Braun V 1990 Iron(III)hydroxamate transport into Escherichia coli. Substrate binding to the periplasmic FhuD protein; J. Biol. Chem. 265 21407-21410
30. Köster W and Böhm B 1992 Point mutations in 2 conserved glycine residues within the integral membrane protein FhuB affect iron(III)hydroxamate transport; Mol. Gen. Genet. 232 399-407
31. Lazazzera B A, Beinert H, Koroshilova N, Kennedy M C and Liley P J 1996 DNA binding and dimerization of the Fe-S-containing FNR protein from Escherichia coli are regulated by oxygen; J. Biol. Chem. 271 2762-2768
32. Lonetto M, Brown K L, Rudd K and Buttner M J 1994 Analysis of the Streptomyces coelicolor sigE gene reveals a new sub-family of eubacterial RNA polymerase factors involved in the regulation of extracytoplasmic functions; Proc. Natl. Acad. Sci. USA 91 7573-7577
33. Lynch A S and Lin E C C 1996 Responses to molecular oxygen; in Escherichia coli and Salmonella (ed.) F C Neidhardt (Washington: ASM Press) pp 1526-1538
34. Mademidis A, Killmann H, Kraas W, Flechsler I, Jung G and Braun V 1997 ATP-dependent ferric hydroxamate transport system in Escherichia coli: periplasmic FhuD interacts with a periplasmic and with a transmembrane/cytoplasmic region of the integral membrane protein FhuB, as revealed by competitive peptide mapping; Mol. Microbiol. 26 1109-1123
35. Martinez A and Kolter R 1997 Protection of DNA during oxidative stress by the nonspecific DNA-binding protein Dps; J. Bacteriol. 179 5188-5194
36. Melville S B and Gunsalus R P 1996 Isolation of an oxygen-sensitive FNR protein of Escherichia coli: interaction at activator and repressor sites of FNR-controlled genes; Proc. Natl. Acad. Sci USA 93 1226-1231
37. Moeck G S, Coulton J W and Postlc K 1997 Cell envelope signaling in Escherichia coli. Ligand binding to the ferrichrome-iron receptor FhuA promotes interaction with the energy-transducing protein TonB; J. Biol. Chem. 272 28391-28397
38. Ochs M, Angerer A, Enz S and Braun V 1996 Surface signaling in transcription regulation of the ferric citrate transport system of Escherichia coli: mutational analysis of the alternative sigma factor Feel supports its essential role in fee transport gene transcription; Mol. Gen. Genet. 250 455-465
39. Paraskeva E and Hentze M W 1996 Iron-sulphur clusters a genetic regulatory switches: the bifunctional iron regulatory protein-1; FEBS Lett. 389 40-43
40. Rohrbach M R, Braun V and Köster W 1995 Ferrichrome transport in Escherichia coli K-12: altered substrate specificity of mutated periplasmic FhuD and interaction of FhuD with the integral membrane protein FhuB; J. Bacteriol. 177 7186-7193
41. Roualt T A and Klausner R D 1996 Iron-sulfur clusters as biosensors of oxidants and iron; Trends Biochem. Sci. 21 174-177
42. Schneider R and Hantke K 1993 Iron-hydroxamate uptake systems in Bacillus subtilis: identification of a lipoprotein as part of a binding protein-dependent transport system; Mol. Microbiol 8 111-121
43. Schöffler H and Braun V 1989 Transport across the outer membrane of Escherichia coli K12 via the FhuA receptor is regulated by the TonB protein in the cytoplasmic membrane; Mol. Gen. Genet. 217 378-383
44. Schultz-Hauser G, Köster W, Schwarz H and Braun V 1992 Iron(III) hydroxamate transport in Escherichia coli K-12: FhuB-mediated membrane association of the FhuC protein and negative complementation of fliuC mutants; J. Bacterial. 174 2305-2311
45. Smith M A, Harris P L, Sayre L M and Perry G 1997 Iron accumulation in Alzheimer disease is a source of rcdoxgeneratcd free radicals; Proc. Natl. Acad. Sci. USA 94 9866-9868
46. Stojiljkovic I and Hantke K 1994 Transport of haemin across the cytoplasmic membrane through a haemin-specific periplasmic-binding-protein-dependent transport system in Yersinia enterocolitica; Mol. Microbiol. 13 719-832
47. Stojiljkovic I, Bäumler A and Hantke K 1995 Fur regulon in gram-negative bacteria, identification and characterization of new iron regulated Escherichia coli genes by a Fur titration assay; J. Mol. Biol. 236 531-545
48. Touati D, Jacques M, Tarda B, Bouchard L and Despied S 1995 Lethal oxidative damage and mutagenesis are generated by iron in Δfur mutants of Escherichia coli: protective role of Superoxide dismutase; J. Bacterial. 177 2305-2314
49. 2-dcpendent gene regulation in facultatively anaerobic bacteria; Arch. Microbiol. 164 81-90