CREB controls LAP/C/EBPβ transcription

Molecular and Cellular Biology

Volumn 17, Issue 7, 1997, Pages 3600-3613

  Niehof, Monika ^a   Manns, Michael P ^a   Trautwein, Christian ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENE DELETION; GENE EXPRESSION REGULATION; GENE INDUCTION; LIVER REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FAMILY; PROTEIN PROCESSING; REPORTER GENE; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION;

EID: 0030962695     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.17.7.3600     Document Type: Article

References (51)

1. Akira, S., H. Isshiki, T. Sugita, O. Tanabe, S. Kinoshita, Y. Nishio, T. Nakajima, T. Hirano, and T. Kishimoto. 1990. A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J. 9:1897-1906.
2. Akira, S., and T. Kishimoto. 1992. IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol. Rev. 127:25-50.
3. Arias, J., A. S. Alberts, P. Brindle, F. X. Claret, T. Smeal, M. Karin, J. Feramisco, and M. Montminy. 1994. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature 370:226-229.
4. Boshart, M., F. Weih, M. Nichols, and G. Schütz. 1991. The tissue-specific extinguisher locus TSE1 encodes a regulatory subunit of cAMP-dependent protein kinase. Cell 66:849-859.
5. Cao, Z., R. M. Umek, and S. L. McKnight. 1991. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5:1538-1552.
6. Chandra, G., J. P. Cogswell, L. R. Miller, M. M. Godlewski, S. W. Stinnett, S. L. Noel, S. H. Kadwell, T. A. Kost, and J. G. Gray. 1995. Cyclic AMP signaling pathways are important in IL-1β transcriptional regulation. J. Immunol. 155:4535-4543.
7. Chang, C.-J., T.-T. Chen, H.-Y. Lei, D.-S. Chen, and S. C. Lee. 1990. Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family. Mol. Cell. Biol. 10:6642-6653.
8. Chang, C.-J., B.-J. Shen, and S.-C. Lee. 1995. Autoregulated induction of the acute-phase response transcription factor gene, agp/ebp. DNA Cell Biol. 14:529-537.
9. Descombes, P., M. Chojkier, S. Lichtsteiner, E. Falvey, and U. Schibler. 1990. LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein. Genes Dev. 4:1541-1551.
10. Descombes, P., and U. Schibler. 1991. A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 67:569-579.
11. Diehl, A. M., S. Q. Yang, D. Wolfgang, and G. Wand. 1992. Differential expression of guanine nucleotide-binding proteins enhances cAMP synthesis in regenerating rat liver. J. Clin. Invest. 89:1706-1712.
12. Ginty, D. D., A. Bonni, and M. E. Greenberg. 1994. Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 77:713-725.
13. Gonzales, G. A., and M. R. Montminy. 1989. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680.
14. Gupta, S., D. Campbell, B. Derijard, and R. J. Davis. 1995. Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267:389-393.
15. Hurst, H. C., N. F. Totty, and N. C. Jones. 1991. Identification and functional characterisation of the cellular activating transcription factor 43 (ATF-43) protein. Nucleic Acids Res. 19:4601-4609.
16. Inoue, H., C. Yokoyama, S. Kara, Y. Tone, and T. Tanabe. 1995. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. J. Biol. Chem. 270:24965-24971.
17. Katz, S., E. Kowenz-Leutz, C. Müller, K. Meese, S. A. Ness, and A. Leutz. 1993. The NF-M transcription factor is related to C/EBPβ and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells. EMBO J. 12:1321-1332.
18. Kowenz-Leutz, E., G. Twamley, S. Ansieau, and A. Leutz. 1994. Novel mechanism of C/EBPβ(NF-M) transcriptional control: activation through derepression. Genes Dev. 8:2781-2791.
19. Kuo, C. J., P. B. Conley, L. Chen, F. M. Sladek, J. E. Darnell, and G. R. Crabtree. 1992. A transcriptional hierarchy involved in mammalian cell-type specification. Nature 355:457-461.
20. Kwok, R. P. S., J. R. Lundblad, J. C. Chrivia, J. P. Richards, H. P. Bächinger, R. G. Brennan, S. G. E. Roberts, M. R. Green, and R. H. Goodman. 1994. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370:223-226.
21. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
22. Livingstone, C., G. Patel, and N. Jones. 1995. ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J. 14:1785-1797.
23. Maher, J. J. 1993. Cell-specific expression of hepatocyte growth factor in liver. J. Clin. Invest. 91:2244-2252.
24. McGrane, M. M., J. S. Yun, A. F. M. Moorman, W. H. Lamers, G. K. Hendrick, B. M. Arafah, E. A. Park, T. E. Wagner, and R. W. Hanson. 1990. Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenol-pyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice. J. Biol. Chem. 265:22371-22379.
25. Mellon, P. L., C. H. Clegg, L. A. Correll, and G. S. McKnight. 1989. Regulation of transcription by cyclic AMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 86:4887-4891.
26. Metz, R., and E. Ziff. 1991. cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to translocate to the nucleus and induce c-fos transcription. Genes Dev. 5:1754-1766.
27. Müller, C., E. Kowenz-Leutz, S. Grieser-Ade, T. Graf, and A. Leutz. 1995. NF-M (chicken C/EBPβ) induces cosinophilic differentiation and apoptosis in a hematopoietic progenitor cell line. EMBO J. 14:6127-6135.
28. Nakajima, T., S. Kinoshita, T. Sasagawa, K. Sasaki, M. Naruto, T. Kishimoto, and S. Akira. 1993. Phosphorylation at threonine 235 by ras-dependent mitogen activated protein cascade is essential for transcription factor NF-IL6. Proc. Natl. Acad. Sci. USA 90:2207-2211.
29. Nguyen, M. T-, S. K. Herrine, and M. A. Zern. 1994. Cytokine involvement in the liver. Curr. Opin. Gastroenterol. 10:277-284.
30. Park, E. A., A. L. Gurney, S. E. Nizielski, P. Hakimi, Z. Cao, A. Moorman, and R. W. Hanson. 1993. Relative roles of CCAAT/enhancer-binding proteinβ and cAMP regulatory element binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP). J. Biol. Chem. 268:613-619.
31. Poli, V., F. P. Mancini, and R. Cortese. 1990. IL-6DBP. a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP. Cell 63:643-653.
32. Roesler, W. J., S. M. Crosson, C. Vinson, and P. J. McFie. 1996. The α-isoform of the CCAAT/enhancer-binding protein is required for mediating cAMP responsiveness of the phosphoenolpyruvate carboxykinase promoter in hepatoma cells. J. Biol. Chem. 271:8068-8074.
33. Russell, W. E., P. J. Dempsey, S. Sitaric, A. J. Peck, and R. J. Coffey. 1993. Transforming growth factor-α (TGFα) concentrations increase in regenerating rat liver: evidence for a delayed accumulation of mature TGFα. Endocrinology 133:1731-1738.
34. Screpanti, I., L. Romani, P. Musiani, A. Modesti, E. Fattori, D. Lazzaro, C. Sellito, S. Scarpa, D. Bellavia, G. Lattanzio, F. Bistoni, L. Frati, R. Cortese, A. Gulino, G. Ciliberto, F. Costantini, and V. Poli. 1995. Lymphoproliferative disorder and imbalanced T-helper response in C/EBPβ-deficient mice. EMBO J. 14:1932-1941.
35. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 251:1427-1430.
36. Tan, Y., J. Rouse, A. Zhang, S. Cariati, P. Cohen, and M. J. Comb. 1996. FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2. EMBO J. 15:4629-4642.
37. Tanaka, T., S. Akira, K. Yoshida, M. Umemoto, Y. Yoneda, N. Shirafuji, H. Fujiwara, S. Suematsu, N. Yoshida, and T. Kishimoto. 1995. Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell 80:353-361.
38. Trautwein, C., G. Ramadori, G. Gerken, K.-H. Meyer zum Büschenfelde, and M. P. Manns. 1992. Regulation of cytochrome p450 IID by acute phase mediators in C3H/HeJ mice. Biochem. Biophys. Res. Commun. 182:617-623.
39. Trautwein, C., C. Caelles, P. van der Geer, T. Hunter, M. Karin, and M. Chojkier. 1993. Transactivation by LAP/NF-IL6 is enhanced by phosphorylation of its activation domain. Nature 364:544-547.
40. Trautwein, C., D. Walker, J. Plümpe, and M. P. Manns. 1995. Transactivation of LAP/NF-IL6 is mediated by an acid domain in the N-terminal part of the protein. J. Biol. Chem. 270:15130-15136.
41. Trautwein, C., T. Rakemann, M. Niehof, S. Rose-John, and M. P. Manns. 1996. Acute-phase response factor, increased binding, and target gene activation during liver regeneration. Gastroenterology 110:1854-1862.
42. Trauewein, C., T. Rakemann, A. Pietrangelo, J. Plümpe, G. Montosi, and M. P. Manns. 1996. C/EBPβ/LAP controls downregulation of albumin gene expression during liver regeneration. J. Biol. Chem. 271:22262-22270.
43. 2 and rat liver regeneration. Gastroenterology 105:495-499.
44. van Dam, H., D. Wilhelm, I. Herr, A. Steffen, P. Herrlich, and P. Angel. 1995. ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J. 14:1798-1811.
45. Wegner, M., Z. Cao, and M. G. Rosenfeld. 1992. Calcium-regulated phosphorylation within the leucine zipper of C/EBPβ. Science 256:370-373.
46. Williams, S. C., C. A. Cantwell, and P. F. Johnson. 1991. A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. Genes Dev. 5:1553-1567.
47. Williams, S. C., M. Baer, A. J. Dillner, and P. F. Johnson. 1995. CRP2 (C/EBPβ) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity. EMBO J. 14:3170-3183.
48. Wu, Z., Y. Xie, N. L. R. Bucher, an S. R. Farmer. 1995. Conditional ectopic expression of C/EBPβ in NIH-3T3 cells induces PPARγ and stimulates adipogenesis. Genes Dev. 9:2350-2363.
49. Xing, J., D. D. Ginty, and M. E. Greenberg. 1996. Coupling of the RASMAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 273:959-963.
50. Yeh, W.-C., Z. Cao, M. Classon, and S. L. McKnight. 1995. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev. 9:168-181.
51. Yin, M., S. Q. Yang, H. Z. Lin, M. D. Lane, S. Chatterjee, and A. M. Diehl. 1996. Tumor necrosis factor α promotes nuclear localization of cytokineinducible CCAAT/enhancer binding protein isoforms in hepatocytes. J. Biol. Chem. 271:17974-17978.