Cytokine mRNA levels in the hearts of inbred mice that develop different degrees of cardiomyopathy during infection with Trypanosoma cruzi

Parasite Immunology

Volumn 20, Issue 10, 1998, Pages 463-471

  Powell, Malcolm R ^a   Morgan, Juliette ^a   Guarner, Jeannette ^b   Colley, Daniel G ^a  

^a U S DEPARTMENT OF HEALTH AND HUMAN SERVICES   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Cardiac pathology; Chagas' disease; Cytokines; Trypanosoma cruzi

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CHAGAS DISEASE; CONTROLLED STUDY; HEART MUSCLE CELL; HISTIOCYTE; HISTOPATHOLOGY; LYMPHOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; STRAIN DIFFERENCE; TRYPANOSOMA CRUZI;

AGE FACTORS; ANIMALS; CHAGAS CARDIOMYOPATHY; CYTOKINES; MALE; MICE; MICE, INBRED DBA; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRYPANOSOMA CRUZI;

ANIMALIA; PROTOZOA; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0031769959     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.1998.00175.x     Document Type: Article

References (37)

1. Aliberti J.C.S., Cardoso M.A.G., Martins G.A. et al. (1996) Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes. Infection and Immunity, 64, 1961-1967
2. Beutler B. & Grau G.E. (1993) Tumor necrosis factor in the pathogenesis of infectious diseases. Critical Care Medicine, 21 (Suppl.), S423-S435
3. Brodskyn C.I., Barral A., Bulhoes M.A. et al. (1996) Cytotoxicity in patients with different clinical forms of Chagas' disease. Clinical and Experimental Immunology 105, 450-455
4. Cerban F.M., Gea S., Menso E. et al. (1993) Chagas' disease: IgG isotypes against Trypanosoma cruzi cytosol antigens in patients with different degrees of heart damage. Clinical Immunology and Immunopathology, 67, 25-30
5. Chandrasekar B., Melby P.C., Troyer D.A. et al. (1996) Induction of proinflammatory cytokine expression in experimental acute chagasic cardiomyopathy. Biochemical and Biophysical Research Communications, 223, 365-371
6. Dutra W.O., Gollub K.J., Pinto Dias J.C. et al. (1997) Cytokine mRNA profile of peripheral blood mononuclear cells isolated-from individuals with chronic Trypanosoma cruzi infection. Scandinavian Journal of Immunology, 45, 74-80
7. Eksi S., Wassom D.L. & Powell M.R. (1996) Host genetics and resistance to acute Trypanosoma cruzi infection in mice. Profiles and compartmentalization of IL-2,4,5,10, and IFN gamma producing cells. Journal of Parasitology, 82, 59-65
8. Gazzinelli G. & Brener Z. (1991) Immunological aspects of the morbidity of human Chagas' disease. Research in Immunology, 142, 167-169
9. Golden J.M. & Tarleton R.L. (1991) Trypanosoma cruzi: cytokine effects on macrophage trypanocidal activity. Experimental Parasitology, 72, 391-402
10. Hunter C.A., Ellisneyes L.A., Slifer T. et al. (1997) IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi. Journal of Immunology, 158, 3311-3316
11. Hunter C.A., Silfer T. & Araujo F. (1996) Interleukin-12 mediated resistance to Trypanosoma cruzi is dependent on tumor necrosis factor alpha and gamma interferon. Infection and Immunity, 64, 2381-2386
12. Laucella S., Salcedo R., Castaños-Velez E. et al. (1996) Increased expression of ICAM-1 during experimental infection with Trypanosoma cruzi. Parasite Immunology, 18, 227-239
13. Levin M.J., Levitus G., Kerner G. et al. (1990) Autoantibodies in Chagas' disease: possible markers of severe Chagas' heart complaint. Memorias do Oswaldo Cruz, 85, 539-543
14. Lima E.C.S., Garcia I., Vicentelli M.H. et al. (1997) Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice. Infection and Immunity, 65, 457-465
15. Moncayo-Medina A. (1987) Chagas Disease. In Tropical Disease Research: A Global Partnership. J. Maurice & A.M Pearce, eds. World Health Organization, Geneva, pp. 87-98
16. Morgan J., Pinto Dias J.C., Gontijo E.D. et al. (1996) Anti-Trypanosoma cruzi antibody isotype profiles in patients with different clinical manifestations of Chagas' disease. American Journal of Tropical Medicine and Hygiene, 55, 355-359
17. Nabors G.S. & Tarleton R.L. (1991) Differential control of IFN-gamma and II-2 production during Trypanosoma cruzi infection. Journal of Immunology, 146, 3591-3598
18. Petray P.B., Rottenberg M.E., Berlot G. et al. (1993) Effect of anti-γ-interferon and anti-interleukin-4 administration on the resistance of mice against infection with reticulotropic and myotropic strains of Trypanosoma cruzi. Immunology Letters, 35, 77-80
19. Pinto Dias J.C. (1985) Historia natural. In Cardiopatia Chagasica. J.R. Cancado & M. Chuster, eds. Fundacao Carlos Chagas, Belo Horizonte, pp. 99-113
20. Primavera K.S.C., Hoshino-Shimizu S., Umezawa E.S. et al. (1988) Immunoglobulin A antibodies to Trypanosoma cruzi antigens in digestive forms of Chagas' disease. Journal of Clinical Microbiology, 26, 2101-2104
21. Reed S.G. (1988) In vivo administration of recombinant IFN-gamma induces macrophage activation, prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infection. Journal of Immunology, 140, 4342-4347
22. Reed S.G., Brownell C.E., Russo D.M. et al. (1994) IL-10 mediates susceptibility in Trypanosoma cruzi infection. Journal of Immunology, 153, 3135-3140
23. Rowland E.C., Lozykowski M.G. & McCormick T.S. (1992) Differential cardiac histopathology in inbred mouse strains chronically infected with Trypanosoma cruzi. Journal of Parasitology, 78, 1059-1066
24. Sa Ferreira J.A., Galvo-Castro B., Macedo E. et al. (1983) Immunoglobulins and other serological parameters in Chagas' disease: evidence for increased IgA levels in chronic digestive form. Clinical and Experimental Immunology, 52, 266-270
25. Starobinos N., Russo M., Minoprio P. et al. (1991) Is TNF alpha involved in early susceptibility of Trypanosoma cruzi-infected C3H/He mice? Research in Immunology, 142, 117-122
26. Street N.E. & Mossman T.R. (1991) Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB Journal, 5, 171-177
27. Sunnemark D., Ulfgren A.-K., Orn A. et al. (1996) Cytokine production in hearts of Trypanosoma cruzi infected CBA mice: Do cytokine patterns in the chronic stage reflect the establishment of myocardial pathology? Scandinavian Journal of Immunology, 44, 421-429
28. Svetic A., Finkelman F.D., Jian Y.C. et al. (1991) Cytokine gene expression after primary in vivo immunization with goat antibody to mouse IgD antibody. Journal of Immunology, 147, 2391-2397
29. Tarleton R.L. (1988) Tumor necrosis factor (cachectin) production during experimental Chagas' disease. Clinical and Experimental Immunology, 73, 186-190
30. Tarleton R.L. & Nabors G.S. (1991 ) Regulation of cytokine production in Chagas' disease. In Molecular and Immunological Aspects of Parasitism. C.C. Wang ed. American Association for the Advancement of Science, Washington, pp. 15-30
31. Torrico F., Heremans H., Rivera M.T. et al. (1991) Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice. Journal of Immunology, 146, 3626-3632
32. Truyens C., Torrico F., Angelbarrios A. et al. (1995) The cachexia associated with Trypanosoma cruzi acute infection in mice is attenuated by anti-TNF-alpha, but not by anti-IL-6 or anti-IFN-gamma antibodies. Parasite Immunology, 17, 561-568
33. Vandekerckhove F., Darji A., Rivera M.T. et al. (1994) Modulation of T-cell responsiveness during Trypanosoma cruzi infection: analysis in different lymphoid compartments. Parasite Immunology, 16, 77-85
34. Wynn T.A., Eltoum I., Cheever A.W. et al. (1993) Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. Journal of Immunology, 151, 1430-1440
35. Wynn T.A., Eltoum I., Oswald I.P. et al. (1994) Endogenous interleukin-12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. Journal of Experimental Medicine, 179, 1551-1561
36. Zhang L. & Tarleton R.L. (1996a) Characterization of cytokine production in murine Trypanosoma cruzi infection by in situ immunocytochemistry: lack of association between susceptibility and T helper type 2 cytokine production. European Journal of Immunology, 26, 102-109
37. Zhang L. & Tarleton R.L. (1996b) Persistent production of inflammatory and anti-inflammatory cytokines and associated MHC and adhesion molecule expression at the sites of infection and disease in experimental Trypanosoma cruzi infections. Experimental Parasitology, 84, 203-213