Remodeling of hyperplastic pituitaries in hypothyroid α-subunit knockout mice after thyroxine and 17β-estradiol treatment: Role of apoptosis

Endocrine Pathology

Volumn 9, Issue 3, 1998, Pages 261-274

  Kulig, Elzbieta ^a   Camper, Sally A ^b   Kuecker, Sara ^a   Jin, Long ^a   Lloyd, Ricardo V ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

17 estradiol; Apoptosis; Pituitary; Thyroxine

Indexed keywords

CORTICOTROPIN; ESTRADIOL; FOLLITROPIN; GROWTH HORMONE; HYPOPHYSIS HORMONE; LUTEINIZING HORMONE; ONCOPROTEIN; PLACEBO; PROLACTIN; PROTEIN BCL 2; THYROTROPIN; THYROXINE;

ALPHA CHAIN; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEMALE; GONADOTROPIN SECRETING CELL; HYPERPLASIA; HYPERTROPHY; HYPOPHYSIS CELL; HYPOPHYSIS DISEASE; HYPOTHYROIDISM; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0031761924     PISSN: 10463976     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02739967     Document Type: Article

References (37)

1. Haggi ES, Torres AI, Maldonado CA, Aoki A. Regression of redundant lactotrophs in rat pituitary gland after cessation of lactation. Endocrinology 11:367-373, 1986.
2. Lloyd RV, Jin L, Fields K, Kulig E. Effects of estrogens on pituitary cell and pituitary tumor growth. Pathol Res Pract 187:584-586, 1991.
3. Girod C, Trouillas J, Caustrat B. The human thyrotropic adenoma: pathologic diagnosis in five cases and critical review of the literature. Semin Diagn Pathol 3:58-68, 1986.
4. Tam SP, Lam KS, Srivastava G. Gene expression of hypothalamic somatostatin, growth hormone releasing factor, and their pituitary receptors in hypothyroidism. Endocrinology 137:418-424, 1996.
5. Wallace H, McLaren K, Al-Shawi R, Bishop JO. Consequences of thyroid hormone deficiency induced by the specific ablation of thyroid follicle cells in adult transgenic mice. J Endocrinol 143:107-120, 1994.
6. Noguchi T, Kuroki T, Yamada T, Sugisaki T, Kubota C, Takamatsu K. Immunocytochemical study of the hypothyroid mouse thyrotroph. Horm Metab Res 27:201-203, 1994.
7. Horvath E, Lloyd RV, Kovacs K. Propylthiouracyl-induced hypothyroidism results in reversible transdifferentiation of somatotrophs into thyroidectomy cells: a morphologic study of the rat pituitary including immunoelectron microscopy. Lab Invest 63:511-520, 1990.
8. Drewett N, Jacobi JM, Willgoss DA, Lloyd HM. Apoptosis in the anterior pituitary gland of the rat: studies with estrogen and bromocriptine. Neuroendocrinology 57:89-95, 1993.
9. Ahbolm E, Grandison L, Zhivotovsky B, Ceccatelli S. Termination of lactation induces apoptosis and alters the expression of the Bcl-2 family members in the rat anterior pituitary. Endocrinology 139:2465-2471, 1998.
10. White E. Life, death and pursuit of apoptosis. Genes Dev 10:1-15, 1996.
11. Rinkenberger JL, Korsmeyer SJ. Errors of homeostasis and deregulated apoptosis. Curr Opin Genet Dev 7:589-596, 1997.
12. Yang E, Korsmeyer SJ. Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood 88:386-401, 1996.
13. Salvesen GS, Dixit VM, Caspases: intracellular signaling by proteolysis. Cell 91:443-446, 1997.
14. Evans-Storms RB, Cidlowski JA. Regulation of apoptosis by steroid hormones. J Steroid Biochem Mol Biol 53:1-8, 1995.
15. Hori M, Nogami T, Itabashi M, Yoshimi F, Ono H, Koizumi S. Expression of Bcl-2 in human breast cancer: correlation between hormone receptor status, p53 protein accumulation and DNA strand breaks associated with apoptosis. Pathol Int 47:757-762, 1997.
16. Kaipia A, Hsu SY, Hsueh AJ. Expression and function of a proapoptotic Bcl-2 family member Bcl-XL/Bcl-2-associated death promoter (BAD) in rat ovary. Endocrinology 138:5497-5504, 1997.
17. Wang TTY, Phang JM. Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7. Cancer Res. 55:2487-2489, 1995.
18. Leff MA, Buckley DJ, Krumenacker JS, Reed JC, Miyashita T, Buckley AR. Rapid modulation of the apoptosis regulatory genes, bcl-2 and bax by prolactin in rat Nb2 lymphoma cells. Endocrinology 137:5456-5462, 1996.
19. Kendall SK, Samuelson LC, Saunders TL, Wood RI, Camper SA. Targeted disruption of the pituitary glycoprotein hormone α-subunit produces hypogonadal and hypothyroid mice. Genes Dev 9:2007-2019, 1995.
20. Gubbay J, Collignon J, Koopman P, Capel B, Economou A, Munsterberg A, Vivian N, Goodfellow P, Lovell-Badge R. A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 346:245-250, 1990.
21. Qian X, Jin L, Grande JP, Lloyd RV. Transforming growth factor-β and p27 expression in pituitary cells. Endocrinology 137:3051-3060, 1996.
22. Jin L, Qian X, Kulig E, Scheithauer BW, Calle-Rodrigue R, Abboud C, Davis DH, Kovacs K, Lloyd RV. Prolactin receptor messenger ribonucleic acid in normal and neoplastic human pituitary tissues. J Clin Endocrinol Metab 82:963-968, 1997.
23. De Zegher F, Pernasetti F, Vanhole C, Devlieger H, Van Den Berghe G, Martial J. The prenatal role of thyroid hormone evidenced by fetomaternal Pit-1 deficiency. J Clin Endocrinol Metab 80:3127-3130, 1995.
24. Escobar-Morreale HF, Obregon MJ, Escobar del Rev F, Morreale de Escobar G. Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats. J Clin Invest 96:2828-2838, 1995.
25. Rodriguez-Garcia M, Jolin T, Santos A, Perez-Castillo A. Effect of perinatal hypothyroidism on the developmental regulation of rat pituitary growth hormone and rhyrotropin genes. Endocrinology 136:4339-4350, 1995.
26. Escobar-Morreale HF, Escobar del Rev F, Obregon MJ, Morreale de Escobar G. Only the combined treatment with thyroxine and triiodothyronine ensures euthyroidism in all tissues of the thyroidectomized rat. Endocrinology 137:2490-2502, 1996.
27. Lloyd RV. Analysis of mammosomatotropic cells in normal and neoplastic human pituitaries. Pathol Res Pract 183:577-579, 1988.
28. Tormanen U, Eerola A-K, Pekka R, Vahakangas K, Soini Y, Sormunen R, Bloigu R, Lehto V-P, Paakko P Enhanced apoptosis predicts shortened survival in non-small cell lung carcinoma. Cancer Res 55:5595-5602.
29. Hino N, Higashi T, Nouso K, Nakatsukasa H, Tsuji T. Apoptosis and proliferation of human hepatocellular carcinoma. Liver 16: 123-129, 1996.
30. Potten CS. What is an apoptotic index measuring? A commentary. Br J Cancer 74:1743-1748, 1996.
31. Bursch W, Paffe S, Putz B, Barthel G, Schulte-Herman R. Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci in rats. Carcinogenesis 11:847-853, 1990.
32. Olsen NJ, Viselli SM, Fan J, Kovacs WJ. Androgens accelerate thymocyte apoptosis. Endocrinology 139:748-752, 1997.
33. Hsu CKA, Rishi AK, Li XS, Dawson MI, Reichert U, Shroot B, Fontana JA. Bcl-xl expression and its downregulation by a novel retinoid in breast carcinoma cells. Exp Cell Res 232:17-24, 1997.
34. VanWeelden K, Flanagan L, Binderup L, Tenniswood M, Welsh J. Apoptotic regression of MCF-7 xenografts in nude mice treated with vitamin D3 analog, EB1089. Endocrinology 139:2102-2110, 1998.
35. Sadrkhanloo R, Hofeditz C, Erickson GF. Evidence for widespread atresia in the hypophysectomized estrogen-treated rat. Endocrinology 120:146-155, 1987.
36. Braw RH, Tsafiri A. Effect of PMSG on follicular atresia in the rat ovary. J Reprod Fertil 59:267-272, 1980.
37. 3) rat pituitary cells. Cancer Res 49:1247-1253, 1989.