Tissue and serum c-erbB-2 and tissue EGFR in breast carcinoma: Three years follow-up

Anticancer Research

Volumn 17, Issue 4 B, 1997, Pages 3101-3105

  Mansour, O A ^a   Zekri, A R ^b   Harvey, Jeann ^c   Teramoto, Y ^c   El Ahmady, O ^a,d  

^a AL AZHAR UNIVERSITY   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c Ciba Corning Diagnostic   (United States)

^d NONE   (Egypt)

Author keywords

Breast cancer; C erbB 2; EGFR

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR; MEMBRANE PROTEIN; ONCOPROTEIN; PROGESTERONE RECEPTOR; PROTEIN TYROSINE KINASE;

ADULT; AGE; BREAST CARCINOMA; BREAST DISEASE; CANCER CELL; CANCER RECURRENCE; CANCER STAGING; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MENOPAUSE; METASTASIS; ONCOGENE C ERB; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTEIN DOMAIN; TISSUE LEVEL; TUMOR VOLUME;

ADULT; AGED; BREAST NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2;

EID: 0030801178     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (26)

1. Shih C, Padhy L, Murray M, and Weinberg R: Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts. Nature 290: 261, 1981.
2. Maguire H and Greene M: The neu (c-erbB-2) Oncogene. Semin Oncol 16: 148-155, 1989.
3. Zabercky J, Lam T, Mckenzie S and Carney W: The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR 3. J Biol Chem 266: 1716-1720, 1990.
4. Leitzel K, Teramoto Y, Sampson E, Mauceri J, Longton B, Demers L, Podczaski E, Harvey H, Shambauph S and Volas G: Elevated soluble c-erb-B2 antigen level in the serum and effusion of breast cancer patients. J Clin Oncol 10: 1436-1443, 1992.
5. Bandyopadhyay D, Redkar A, Bharde S, Dani H, Sampat M and Mittra I: Prognostic association of c-erbB-2 oncogene amplification and protein over expression in human breast cancer using archival tissues. A comparative study. Act Once 33: 493-498, 1994.
6. Hubbard A, Doris C, Thompson A, Chetty U and Anderson T. Critical determination of the frequency of c-erbB-2 amplification in breast cancer. Br J Cancer 70: 434-439, 1994.
7. Kandl H, Seymor L, Bezwoda W: Soluble c-erbB-2 fragment in serum correlates with the disease stage and predict for shortened survival in patients with early stage and advanced breast cancer. Br J Cancer 70: 739-742, 1994.
8. Leitzel K, Teramoto Y, Konrad K, Chinchilli V, Volas G, Grossberg M, Harvey H, Demers L, and Lipton A: Elevated serum c-erbB-2 antigen level and decreased response to hormone therapy of breast cancer. Proc Annu Meet Am Soc Clin Oncol 13: A1520, 1994.
9. Harslev T, and Jacbbsen G: c-erbB-2 oncoprotein is not an independant prognostic parameter in primary breast carcinoma: An immunohistochmical study. APMIS 102: 612-622, 1994.
10. Horigushi J, Iiono Y, Takei H, Yokoe T, Ishida T, and Morishita Y. Immunohistochemical study on the expression of c-erbB-2 onco-protein in breast cancer. Oncology 51: 47-51, 1994.
11. Narita T, Funahashi H, Sotoh Y, Imai T, and Takaji H: Quantitative analysis of c-erbB-2 protein in breast cancer tissue by enzyme immunoassay. Jpn J Clin Oncol 24: 74-78, 1994.
12. Noguchi M, Mizukami Y, Kinoshita K, Earashi M and Miyazaki I: c-erbB-2, ras 21 and c-myc expression in breast carcinoma: prognostic value and correlation with clinicopathologic and biologic variables. Int J Oncol 4/1: 255-60, 1994.
13. Scorilas A, Yotis J, Gouriotis D, Keramopoulos A, Ampela K, Trangas T, and Talieri M: Cathepsin D and c-erbB-2 have an additive prognostic value for breast cancer patients. Anticancer Res 13: 1895-1900, 1993.
14. Bradford M: A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72: 248-254.
15. Isola J, Holli K, Oksa H, Teramoto Y, and Kallioniemi O: Elevated erbB-2 oncoprotein levels in preoperative and follow-up serum samples define an aggressive disease course in patients with breast cancer. Cancer 73: 652-658, 1994.
16. Watanabe N, Miyamoto M, Tokuda Y, Kubota M, Ando Y, Tajima T and Mitomi T: Serum c-erbB-2 in breast cancer patients. Acta Oncol 33: 901-904, 1994.
17. Koenders E, Faverly D, Bees L, Burggink C and Benraad T: Epidermal growth factor receptors in human breast cancer: a plea for standardization for assay methodology. Eur J Cancer 28: 693-697, 1992.
18. Klijn J, Berns P, Schmitz P, and Foekens J: The clinical significance of EGFR in human breast cancer: a review on 5232 patients. Endocrine Reviews 13: 3-17, 1992.
19. Heatly M, Maswell P, Whiteside E, and Toner P. c-erbB-2 oncogene product expression depends on tumor type and is related to ER and lymph node status in human breast carcinoma. Path Res Pract 189: 261-266, 1993.
20. Tandon A, Clarak G, Chamness G, Ullrich A, and McGuire W: HER-2/neu oncogene protein and prognosis in breast cancer. J Clin Oncol 7: 1120-1128, 1989.
21. Wright C, Angus B, Nicholson S, Saisbury G, Gullick W, Kelly P, Harris A and Home C: Expression of c-erbB-2 oncoprotein: a prognostic indicator in breast cancer Cancer Res 49: 2087, 1989.
22. Gasparini G, Bevilacqua P, Pozza F, Meli S, Boracchi P, Marubini E, and Sainsbury: Value of epidermal growth factor receptor status compared with growth traction and other factors for prognosis in early breast cancer. Br J Cancer 66: 970-976, 1992.
23. Chrysogelos S and Dickson R: EGF receptor expression, regulation and function in breast cancer. Breast Cancer Res Treat 29: 29-40, 1994.
24. Railo M, Smitten K and Pekonen F: The prognostic value of epidermal growth factor receptor in breast cancer patients: result of follow-up study on 149 patients. Acta Oncol 33: 13, 1994.
25. Murrai P, Parrett L,Travers M, Luqmani Y, Pules T and Coombes R: The prognostic significance of transforming growth factors in human breast cancer Br J Cancer 67: 1408, 1993.
26. Coombes R, Barrett L and Luqmani Y: Growth factor expression in breast cancer J Steroid Biochem Mol Biol 37: 833, 1990.