Timing of dietary fat exposure and mammary tumorigenesis: Role of estrogen receptor and protein kinase C activity

Molecular and Cellular Biochemistry

Volumn 188, Issue 1-2, 1998, Pages 5-12

  Hilakivi Clarke, Leena ^a,b   Clarke, Robert ^a,c  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

Author keywords

Breast cancer; Dietary fat; Estradiol; Estrogen; Polyunsaturated fatty acid; Pregnancy

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; LINOLEIC ACID; POLYUNSATURATED FATTY ACID; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; BREAST CARCINOGENESIS; CHEMICAL CARCINOGENESIS; CONFERENCE PAPER; ENZYME ACTIVITY; ESTRADIOL BLOOD LEVEL; ESTROGEN ACTIVITY; FAT INTAKE; FEMALE; FETUS DEVELOPMENT; MATERNAL NUTRITION; NONHUMAN; PUBERTY; RAT;

ANIMALS; BREAST NEOPLASMS; DIETARY FATS; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; PREGNANCY; PROTEIN KINASE C; RECEPTORS, ESTROGEN; RISK FACTORS;

ANIMALIA;

EID: 0031726253     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006827229431     Document Type: Conference Paper

References (82)

1. Boyd NF, Cousins M, Lockwood G, Tritchler D: The feasibility of testing experimentally the dietary fat-breast cancer hypothesis. Br J Cancer 62: 878-881, 1990
2. Carroll KK, Khor HT: Dietary fat in relation to tumorigenesis: In: Progress in Biochemistry and Pharmacology. Basel, Karger, 1975, pp 308-353
3. Howe GR, Hirohata T, Hislop TG, Iscovich JM, Yuan JM, Katsoyanni K, Lubin F, Marubini F, Modan B, Roban T: Dietary factors and risk of breast cancer: combined analysis of 12 case-control studies. J Nat Cancer Inst 82: 561-569, 1990
4. Boyd NF, Martin LJ, Noffel M, Lockwood GA, Tritchler DL: A meta-analysis of studies of dietary at and breast cancer risk. Br J Cancer 68: 627-636, 1993
5. Welsch CW: Relationship between dietary fat and experimental mammary tumorigenesis: A review and critique. Cancer Res 52: 2040-2048, 1992
6. Fay MP, Freedman LS: Analysis of dietary fats and mammary neoplasms in rodent experiments. Breast Cancer Res Treat 46: 215-223, 1997
7. Hunter DJ, Spiegelman D, Adami HO, Beeson L, van den Brandt PA, Folsom AR, Fraser GE, Goldbohm RA, Graham S, Howe GR, Kushi LH, Marshall JR, McDermott A, Miller AB, Speizer FE, Wolk A, Yuan S, Willett W: Cohort studies of fat intake and the risk of breast cancer - a pooled analysis. N Engl J Med 334: 356-361, 1996
8. Hilakivi-Clarke LA: Mechanisms of high maternal fat intake during pregnancy on increased breast cancer risk in female rodent off spring. Breast Cancer Res Treat 46: 119-214, 1997
9. Adlercreutz H, Gorbach SL, Goldin BR, Woods MN, Dwyer JT, Hamalainen H: Estrogen metabolism and excretion in oriental and Caucasian women. J Natl Cancer Inst 86: 1076-1082, 1994
10. Thomas DB, Karagas MR: Cancer in first and second generation Americans. Cancer Res 47: 5771-5776, 1987
11. Ziegler RG, Hoover RN, Pike MC, Hildesheim A, Nomura AMY, West DW, Wu-Williams AH, Kolonel LN, Horn-Ross PL, Rosenthal JF, Hyer MB: Migration patterns and breast cancer risk in Asian-American women. J Natl Cancer Inst 85: 1819-1827, 1993
12. Walker BE: Tumors in female offspring of control and diethylstilbestrol-exposed mice fed high-fat diets. J Nat Cancer Inst 82: 50-54, 1990
13. Hilakivi-Clarke L, Clarke R, Onojafe I, Raygada M, Cho E, Lippman ME: A maternal diet high in n-6 polyunsaturated fats alters mammary gland development, puberty onset, and breast cancer risk among female rat offspring. Proc Natl Acad Sci USA 94: 9372-9377, 1997
14. Clarke R, Dickson RB, Lippman ME: Hormonal aspects of breast cancer. Growth factors, drugs and stromal interactions. Crit Rev Oncol Hematol 12: 1-23, 1992
15. Goldin BR, Adelercreutz H, Gorbach SL, Warram JH: Estrogen excretion patterns and plasma levels in vegetarian and omnivorous women. N Engl J Med 307: 1452-1547, 1982
16. Bennett FC, Ingram DM: Diet and female sex hormone concentrations: an intervention study for the type of fat consumed. Am J Clin Nutr 52: 808-812, 1990
17. Rose DP, Boyar AP, Cohen C, Strong LE: Effect of a low-fat diet on hormone levels in women with cystic breast disease. J Natl Cancer Inst 78: 623-626, 1987
18. Rose DP, Connolly JM, Chlebowski RT, Buzzard IM, Wynder EL: The effects of a low-fat dietary intervention and tamoxifen adjuvant therapy on the serum estrogen and sex hormone-binding globulin concentrations of postmenopausal breast cancer patients. Breast Cancer Res Treat 27: 253-262, 1993
19. Chan PC, Head JF, Cohen LA, Wynder EL: Influence of dietary fat on the induction of mammary tumors by nitrosomethylurea: Associated hormone changes and differences between Sprague- Dawley and F344 rats. J Natl Cancer Inst 39: 1279-1283, 1977
20. Ip C, Ip MM: Serum estrogens and estrogen responsiveness in 7, 12-dimethylbenz(a) anthracene-induced mammary tumors as influenced by dietary fat. J Natl Cancer Inst 66: 291-295, 1981
21. Hilakivi-Clarke L, Onojafe I, Raygada M, Cho E, Clarke R, Lippman M: High-fat diet during pregnancy increases breast cancer risk in rats. J Natl Cancer Inst 88: 1821-1827, 1996
22. Welsch CW: Review of the effects of dietary fat on experimental mammary gland tumorigenesis: Role of lipid peroxidation. Free Radic Biol Med 18: 757-773, 1995
23. Stubbs CD, Smith AD: Modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function. Biochim Biophys Acta 779: 89-137, 1984
24. Rose DP: Effects of dietary fatty acids on breast and prostate cancers: Evidence from in vitro experiments and animal studies. Am J Clin Nutr 66: 1513S-1522S, 1997
25. Greenblatt RB, Colle ML, Mahesh VB: Ovarian and adrenal steroid production on the postmenopausal women. Obstet Gynecol 47: 383-387, 1976
26. Noble LS, Simpson HR, Johns A, Bulun SE: Aromatase expression in endometriosis. J Clin Endocrin Metab 81: 179 1996
27. Bruning PF, Bonfrer JMG: Possible relevance of steroid availability and breast cancer. Ann NY Acad Sci 257-264, 1990
28. Holderegger C, Keefer D: The ontogeny of the mouse estrogen receptor: The pelvic region. Am J Anatomy 177: 285-297, 1986
29. Muldoon TG: Steroid hormone receptor regulation by various hormonal factors during mammary development and growth in the normal mouse. Ann NY Acad Sci 464: 17-36, 1986
30. Anderson E, Clarke RB, Howell A: Changes in the normal human breast throughout the menstrual cycle: Relevance to breast carcinogenesis. Endocrine-related Cancer 4: 23-33, 1997
31. Kelly PA, Dijiane J, Malancon R: Characterization of estrogen, progesterone and glucocorticoid receptors in rabbit mammary glands and their measurement during pregnancy and lactation. J Steroid Biochem 18: 215-221, 1983
32. Yu WC, Leung BS: Variation of cytoplasmic content of estrogen and progesterone receptors in the mammary gland and uterus of rats at time of parturition. Biol Reprod 27: 658-664, 1982
33. Haslam SZ, Nummy KA: The ontogeny and cellular distribution of estrogen receptors in normal mouse mammary gland. J Steroid Biochem Mol Biol 42: 589-595, 1992
34. McGuire WL, Carbone PP, Sears ME, Escher GC: Estrogen receptors in human breast cancer: An overview. In: W.L. McGuire, P.P. Carbone, M.E. Sears, G.C. Escher (eds). Estrogen Receptors in Human Breast Cancer. Raven Press, New York, 1975, pp 1-7
35. Netto GJ, Cheek JH, Zachariah NY, Romer JC, Lee CF, Schoenfeld R, Chakmakjian ZH: Steroid receptors in benign mastectomy tissue. Am J Clin Pathol 94: 14-17, 1990
36. Blancho G, Alavaikko M, Ojala A, Collan Y, Hietanen T, Aine R, Taskinen PJ: Estrogen and progesterone receptos in breast cancer: Relationships to tumor histopathology and survival of patients. Anticancer Res 4: 383-390, 1984
37. Singh L, Wilson AJ, Baum M, Whimster WH, Birch IH, Jackson IM, Lowrey C, Palmer MK: The relationship between histological grade, oestrogen receptor status, events and survival at 8 years in the NATO (Nolvadex) trial. Br J Cancer 57: 612-614, 1988
38. Henry JA, Nicholson JA, Farndon JR, Westley BR, May F: Measurement of oestrogen mRNA levels in human breast tumors. Br J Cancer 58: 600-605, 1988
39. Anatnades K, Spector H: Quantitative estrogen receptor values and growth of carcinoma of the breast before surgical intervention. Cancer 50: 793-796, 1982
40. Meyers JS, Rao BR, Stevens SC, White WL: Low incidence of estrogen receptor in breast carcinomas with rapid rates of cellular proliferation. Cancer 40: 2290-2298, 1977
41. Aamdal S, Bormer O, Jorgensen O, Host H, Eilassen G, Kaalhus O, Pihl A: Estrogen receptor and long term prognosis in breast cancer. Cancer 33: 2325-2329, 1984
42. Clark GM, McGuire WL: Seroid receptors and other prognostic factors in primary breast cancer. Semin Oncol 13: 20-23, 1988
43. Honig SF: Treatment of metastatic disease: hormonal therapy and chemotherapy. In: J.R. Harris, M.E. Lippman, M. Morrow, S. Hellman (eds). Diseases of the Breast. Lipponcott-Raven, Philadelphia, 6, pp 669-734
44. Hilakivi-Clarke LA, Raygada M, Stoica A, Martin M-B: Consumption of a high-fat diet during pregnancy alters estrogen receptor content, protein kinase C activity and morphology of mammary gland in the mother and her female offspring. Cancer Res 58: 634-660, 1998
45. Potter JD, Cerhan JR, Sellers TA, McGovern PG, Drinkard C, Kushi LR, Folsom AR: Progesterone and estrogen receptors and mammary neoplasia in the Iowa Women's Health Study: How many kinds of breast cancer are there. J Natl Cancer Inst 85: 32-36, 1993
46. Holm L-E, Nordevang E, Hjalmar ML, Lidbrink H, Callmer E, Nilsson B: Treatment failure and dietary habits in women with breast cancer. J Natl Cancer Inst 85: 32-36, 1993
47. Willett WC, Hunter DJ: Prospective studies of diet and breast cancer. Cancer 74: 1085-1089, 1994
48. Witte JS, Ursin G, Siemiatycki J, Thompson WD, Paganini-Hill A, Haile RW: Diet and premenopausal bilateral breast cancer: A case-control study. Breast Cancer Res Treat 42: 243-251, 1997
49. Russo IH, Medado J, Russo J: Endocrine influences on the mammary gland. In: T.C. Jones, U. Mohr, R.D. Hunt (eds). Integument and Mammary Glands. Springer-Verlag, Berlin, 1994, pp 252-266, 1994
50. Bern HA, Mills KT, Edery M: Estrogen-associated defects in rodent mammary gland development. In: J.A. McLachlan (ed.). Estrogens in the Environment, Elsevier, The Netherlands, 1985, pp 319-326,
51. Verhoeven G, Vandoren G, Heyns W, Kuhn ER, Janssens JP, Teuwen D, Goddeeris E, Lesaffre E, DeMoor P: J Endocrinol 95: 357-368, 1982
52. Kuiper GGJM, Enmark H, Pelto-Huikko M, Nilsson S, Gustafsson JA: Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc Natl Acad Sci USA 93: 3923-3930, 1996
53. Kuiper GGJM, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA: Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138: 863-870, 1997
54. Vladusic EA, Hornby AK, Guerra FK, Lupu R: Expression of ERbeta in breast cancer cells: Does it play an improtant role? Proc Am Assoc Cancer Res 88, Abstract 1993, 1997
55. Nishizuka Y: Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C. Science 238: 607-614, 1992
56. Dekker LV, Parker PJ: Protein kinase C - a question of specificity. Trends Biochem Sci 19: 73-77, 1994
57. Cutler RE, Maizels ET, Hunzicker-Dunn M: delta protein kinase-C in the rat ovary: Estrogen regulation and localization. Endocrinology 133: 1669-1678, 1994
58. Tzukerman M, Zhang XK, Pfahl M: Inhibition of estrogen receptor activity by the tumor promoter 12-O-Tetradecanylphorbol- 13 -Acetate: A molecular analysis. Mol Endocrinol 5: 1893-1992, 1991
59. Saceda M, Knabbe C, Dickson RB, Lippman ME, Bronzert D, Lindsey RL, Gottardis M, Martin M-B: Post transcriptional destabilization of estrogen receptor mRNA in MCF-7 cells by 12-O-tetradecanolphorbol-13-acetate. J Biol Chem 266: 17809-17814, 1991
60. Martin M-B, Garcia-Morales P, Stoica A, Harrison BS, Pierce M, Katz D, Zhang S, Danielson M, Saceda M: Effects of 12-O-tetradecanoylphorbol-13-acetate on estrogen receptor activity in MCF-7 cells. J Biol Chem 270: 23244-23231, 1995
61. O'Brian CA, Ward N: Biology of the protein kinase C family. Cancer Metast Rev 8: 199-214, 1989
62. Ways DK, Kukoly CA, de Vente J, Hooker JL, Bryant WO, Posekany KJ, Fletcher DJ, Cook PP, Parker PP: MCF-7 breast cancer cells transfected with PKC-alpha exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype. J Clin Invest 95: 1906-1915, 1995
63. Manni A, Buckalter E, Etindi R, Kunselman S, Rossini A, Mauger D, Dabbs D, Deniers L: Induction of less aggressive breast cancer phenotype by protein kinase-alpha and beta overexpression. Cell Growth Diff: 1187-1198, 1996
64. Choe M, Kris ES, Luthra R, Copenhaver J, Pelling JC, Donnelly TE, Birt DE: Protein kinase C is activated and diacylglycerol is elevated in epidermal cells from SENCAR mice fed high fat diets. J Nutr 122: 2322-2329, 1992
65. Kris E, Choe M, Luthra R, Conway H, Barnett T, Yakine A, Birt DE: Protein kinase C activity is reduced in epidermal cells from energy restricted SENCAR mice. J Nutr 124: 485-492, 1994
66. Reddy BS, Simi B, Patel N, Aliaga C, Rao CV: Effect of amount and types of dietary fat on intestinal bacterial 7 alpha-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during different stages of colon tumor promotion. Cancer Res 56: 2314-2320, 1996
67. Birt DE, Barnett T, Pour PM, Copenhaver J: High-fat diet blocks the inhibition of skin carcinogenesis and reductions in protein kinase C by moderate energy restriction. Mol Carcinogenesis 16: 115-120, 1996
68. Russo J, Gusterson BA, Rogers AK, Russo IH, Wellings SR, van Zwieten MJ: Comparative study of human and rat mammary tumorigenesis. Lab Invest 62: 244-278, 1990
69. Russo J, Romero AL, Russo IH: Architectural pattern of the normal and cancerous breast under the influence of parity. Cancer Epidemiol Biomarkers Prev 3: 219-224, 1994
70. Krane LM, Leder P: NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammay glands of transgenic mice. Oncogene 12: 1781-1788, 1996
71. Hilakivi-Clarke L, Cho E, Raygada M, Kenney N: Alterations in mammary gland development following neonatal exposure to estradiol, transforming growth factor alpha, and estrogen receptor antagonist ICI 182, 780. J Cell Physiol 170: 279-289, 1997
72. Wolk A, Bergström R, Hunter D, Willett W, Ljung H, Holmberg L, Bergkvist L, Bruce A, Adami HO: A prospective study of association of monounsaturated fat and other types of fat with risk of breast cancer. Arch Intern Med 158: 41-45, 1998
73. Toniolo PG, Levitz M, Zeleniuh-Jacquette A, Banerjee S, Koenig KL, Shore RE: A prospective study of endogenous estrogens and breast cancer in postmenopausal women. J Natl Cancer Inst 87: 190-197, 1995
74. Ingram D, Nottage E, Ng S, Sparrow L, Roberts A, Willcox D: Obesity and breast cancer. Cancer 64: 1049-1053, 1989
75. Weiss HA, Potischman N, Brinton LA, Brogan D, Coates RJ, Gammon MD, Malone KE, Schoenberg JB: Prenatal and perinatal risk factors for breast cancer in young women. Epidemiology 8: 181-187, 1997
76. Braun MM, Ahlbom A, Floderus B, Brinton LA, Hoover RN: Effect of twinship on incidence of cancer of the testis, breast, and other sites. Cancer Causes Control 6: 519-524, 1995
77. Swetdlow AJ, Stavola BLD, Swanwick MA, Maconochie NES: Risk of breast and testicular cancers in young adult twins in England and Wales: evidence on prenatal and genetic aetiology. Lancet 350: 1723-1728, 1997
78. Michels KB, Trichopoulos D, Robins JM, Rosner BA, Manson JE, Hunter D, Colditz GA, Hankinson SE, Speizer FE, Willett WC: Birth-weight as a risk factor for breast cancer. Lancet 348: 1542-1546, 1996
79. Sanderson M, Williams M, Malone KE, Stanford JL, Emanuel I, White E, Daling JR: Perinatal factors and risk of breast cancer. Epidemiology 7: 34-37, 1996
80. Ekbom A, Trichopoulos D, Adami HO, Hsieh CC, Lan SJ: Evidence of prenatal influences on breast cancer risk. Lancet 340: 1015-1018, 1992
81. Ekbom A, Hsieh C-c, Lipworth L, Adami H-O, Trichopoulos D: Intrauterine environment and breast cancer risk in women: A population-based study. J Natl Cancer Inst 89: 71-76, 1997
82. Brandenberger AW, Tee MK, Lee JY, Chao V, Jaffe RB: Tissue distribution of estrogen receptor α (ERα) and β (ERβ) mRNA in the mid gestational human fetus. J Clin Endocrinol Metab 82: 3509-3512