Alterations in mammary gland development following neonatal exposure to estradiol, transforming growth factor α, and estrogen receptor antagonist ICI 182,780

Journal of Cellular Physiology

Volumn 170, Issue 3, 1997, Pages 279-289

  Hilakivi Clarke, Leena ^a,b   Cho, Elizabeth ^a   Raygada, Margarita ^a   Kenney, Nicholas ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; DIETHYLSTILBESTROL; ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT; GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CONTROLLED STUDY; DRUG ACTIVITY; FEMALE; HUMAN CELL; MODULATION; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0030980461     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199703)170:3<279::AID-JCP9>3.0.CO;2-L     Document Type: Article

References (36)

1. Bates, S.E., Davidson, N.B., Valverius, E.M., Freter, C.E., Dickson, R.B., Tam, J.P., Kudlow, J.E., Lippman, M.E., and Salomon, D.S. (1988) Expression of transforming growth factorα and its messenger ribonucleic acid in human breast cancer: its regulation by estrogen and its possible functional significance. Mol. Endocrinol., 2:543-555.
2. Coleman, S., Silberstein, G.B., and Daniel, C.W. (1988) Ductal morphogenesis in the mouse mammary gland: evidence supporting a role for epidermal growth factor. Dev. Biol., 127:304-315.
3. Derynck, R. (1988) Transforming growth factor α. Cell, 54:593-595.
4. Engelman, R.W., Day, N.K., and Good, R.A. (1994) Caloric intake during mammary development influences cancer risk: lasting inhibition of C3H/HeOu mammary tumorigenesis by peripubertal caloric restriction. Cancer Res., 54:5724-5730.
5. Ethier, S.P. (1995) Growth factor synthesis and human breast cancer progression. J. Natl. Cancer Inst., 87:964-973.
6. Haslam, S.Z. (1988) Progesterone effects on deoxyribonucleic acid synthesis in normal mouse mammary glands. Endocrinology, 122:464-470.
7. Hilakivi-Clarke, L., Clarke, R., Onojafe, I., Raygada, M., Cho, E., and Lippman, M.E. (1996) A maternal diet high in polyunsaturated fats increases mammary epithelial density and breast cancer risk among female rat offspring (submitted, 1996).
8. Jhappan, C., Stahle, C., Harkins, R.N., Fausto, N., Smith, G.H., and Merlino, G.T. (1990) TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell, 61:1137-1146.
9. Jones, L.A., and Bern, H.A. (1979) Cervicovaginal and mammary gland abnormalities in BALB/cCrg1 mice treated neonatally with progesterone and estrogen, alone or in combination. Cancer Res., 39:2560-2567.
10. Kenney, N., Johnsoh, G., Selvam, M.P., Kim, N., Qi, C.F., Saeki, T., Brandt, R., Jones, B.W., Ciardiello, F., Shoyab, M., Plowman, G., Day, A., Salomon, D.S., and Normanno, N. (1993) Transforming growth factor alpha (TGF alpha) and amphiregulin (AR) as autocrine growth factors in nontransformed immortalized 184AIN4 human mammary epithelial cells. Mol. Cell Diff., 1:163-184.
11. Kenney, N.J., Saeki, T., Gottardis, M., Kim, N., Garcia-Morales, P., Martin, M.B., Normanno, N., Ciardiello, F., Day, A., Cutler, M.L., and Salomon, D.S. (1993) Expression of transforming growth factor α antisense mRNA inhibits the estrogen-induced production of TGFa and estrogen-induced proliferation of estrogen-responsive human breast cancer cells. J. Cell. Physiol., 156:497-514.
12. Korach, K.S. (1994) Insights from the study of animals lacking functional estrogen receptor. Science, 266:1524-1527.
13. Krane, I.M., and Leder, P. (1996) NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammay glands of transgenic mice. Oncogene, 12:1781-1788.
14. Lippman, M.E., Monaco, M.E., and Bolan, G. (1977) Effects of estrogen, estradiol and estriol on hormone-responsive human breast cancer in long-term tissue culture. Cancer Res., 37:1901-1907.
15. Lopez, J., Ogren, L., Verjan, R., and Talamantes, F. (1988) Effects of perinatal exposure to a synthetic estrogen and progestin on mammary tumorigenesis in mice. Teratology, 38:129-134.
16. Matsui, Y., Halter, S.A., Holt, J.T., Hogan, B.L.M., and Coffey, R.J. (1990) Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice. Cell, 61:1147-1155.
17. McDonnell, D.P., Clemm, D.L., Hermann, T., Goldman, M.E., and Pike, J.W. (1995) Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. Mol. Endocrinol., 9:659-669.
18. Medina, D., Kittrell, F.S., Oborn, C.J., and Schwartz, M. (1993) Growth factor dependency and gene expression in preneoplastic mouse mammary epithelial cells. Cancer Res., 53:668-674.
19. Mori, T., Bern, H.A., Mills, K.T., and Young, P.N. (1976) Long-term effects of neonatal steroid exposure on mammary gland development and tumorigenesis in mice. J. Natl. Cancer Inst., 57:1057-1062.
20. Russo, I.H., Medado, J., and Russo, J. (1994) Endocrine influences on the mammary gland. In: Integument and Mammary Glands. T.C. Jones, U. Mohr, and R.D. Hunt, eds. Springer-Verlag, Berlin, pp. 252-266.
21. Russo, J., and Russo, I.H. (1987) Biological and molecular bases of mammary carcinogenesis. Lab. Invest., 57:112-137.
22. Russo, J., Gusterson, B.A., Rogers, A.E., Russo, I.H., Wellings, S.R., and van Zwieten, M.J. (1990) Comparative study of human and rat mammary tumorigenesis. Lab. Invest., 62:244-278.
23. Russo, J., Romero, A.L., and Russo, I.H. (1994) Architectural pattern of the normal and cancerous breast under the influence of parity. Cancer Epidemiol. Biomarkers Prev., 3:219-224.
24. Salomon, D.S., Dickson, R.B., Normanno, N., Saeki, T., Kim, N., Kenney, N., and Ciardiello, F. (1992) Interaction of oncogenes and growth factors in colon and breast cancer. Curr. Perspect. Mol. Cell. Oncol., 211-261.
25. Sandgren, E.P., Luetteke, N.C., Palmiter, R.D., Brinster, R.L., and Lee, D.C. (1990) Overexpression of TGFα in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell, 61:1121-1135.
26. Seibert, K., Shafie, S.M., Triche, T.J., Whang-Peng, J.J., O'Brien, S.J., Toney, J.H., Huff, K.K., and Lippman, M.E. (1983) Clonal variation of MCF-7 breast cancer cells in vitro and in athymic nude mice. Cancer Res., 43:2223-2239.
27. Smith, J.M., Sporn, M.B., Roberts, A.B., Derynck, R., Winkler, M.E., and Gregory, H. (1985) Human transforming growth factorα causes precocious eyelid opening in newborn mice. Nature, 315:515-516.
28. Tam, J.P. (1985) Physiological effects of transforming growth factor in the newborn mouse. Science, 229:673-675.
29. Tamooka, T., and Bern, H.A. (1982) Growth of mouse mammary glands after neonatal sex hormone treatment. J. Natl. Cancer Inst., 69:1347-1352.
30. Tora, L., White, J., Brou, C., Tasset, D., Webster, N., Scheer, E., and Chambon, P. (1989) The human estrogen receptor has two identical nonacidic transcriptional actavation functions. Cell, 59:477-487.
31. Vonderhaar, B.K. (1987) Local effects of EGF, alpha-TGF, and EGF-like growth factors on lobuloalveolar development of the mouse mammary gland in vivo. J. Cell. Physiol., 132:581-584.
32. Vonderhaar, B.K. (1988) Regulation of development of the normal mammary gland by hormones and growth factors. In: Breast Cancer: Cellular and Molecular Biology. M.E. Lippman and R.B. Dickson, eds. Kluwer Academic Publishers, Boston, pp. 251-266.
33. Walker, B.E. (1984) Tumors of female offspring of mice exposed prenatally to diethylstilbestrol. J. Natl. Cancer Inst., 73:133-140.
34. Walker, B.E. (1990) Tumors in female offspring of control and diethylstilbestrol-exposed mice fed high-fat diets. J. Natl. Cancer Inst., 82:50-54.
35. Warner, M.R. (1976) Effect of various doses of estrogen to BALB/ cCrgl neonatal female mice on mammary growth and branching at 5 weeks of age. Cell Tissue Kinet., 9:429-438.
36. Wilcox, J.N., and Derynck, R. (1988) Developmental expression of transforming growth factor alpha and beta in mouse fetus. Mol. Cell. Biol., 8:3415-3422.