Coronary endothelial P-selectin in pathogenesis of myocardial ischemia- reperfusion injury

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 275, Issue 5 44-5, 1998, Pages

  Palazzo, Anthony J ^a   Jones, Steven P ^a   Anderson, Donald C ^b   Granger, D Neil ^a   Lefer, David J ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

^b PFIZER INC   (United States)

Author keywords

Adhesion molecules; Infarction; Monoclonal antibody; Mouse; Neutrophil

Indexed keywords

PADGEM PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY ENDOTHELIUM; ARTICLE; CORONARY ARTERY; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REPERFUSION INJURY;

EID: 0031724766     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.275.5.h1865     Document Type: Article

References (36)

1. Barry, W. H. Mechanisms of myocardial cell injury during ischemia and reperfusion. J. Card. Surg. 2: 375-383, 1987.
2. x analog blocker of the selectin adhesion molecules, on infarct size and "no-reflow" in the rabbit model of acute myocardial infarction/reperfusion. J. Mol. Cell. Cardiol. 29: 2013-2025, 1997.
3. Braunwald, E. Myocardial reperfusion, limitation of infarct size, reduction of left ventricular dysfunction, and improved survival. Should the paradigm be expanded? Circulation 79: 441-444, 1989.
4. Braunwald, E., and R. A. Kloner. Myocardial reperfusion: a double edged sword. J. Clin. Invest. 76: 1713-1719, 1985.
5. x-containing oligosaccharide attenuates myocardial reperfusion injury in cats. J. Clin. Invest. 93: 1140-1148, 1994.
6. Bullard, D. C., L. Qin, I. Lorenzo, W. M. Quinlin, N. A. Doyle, R. Bosse, D. Vestweber, C. M. Doerschuk, and A. L. Beaudet. P-selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli. J. Clin. Invest. 95: 1782-1788, 1995.
7. Connolly, E. S., Jr., C. J. Winfree, C. J. Prestigiacomo, S. C. Kim, T. F. Choudhri, B. L. Hoh, Y. Naka, R. A. Solomon, and D. J. Pinsky. Exacerbation of cerebral injury in mice that express the P-selectin gene: identification of P-selectin blockade as a new target for the treatment of stroke. Circ. Res. 81: 304-310, 1997.
8. Doerschuk, C. M., W. M. Quinlin, N. A. Doyle, D. C. Bullard, D. Vestweber, M. L. Jones, F. Takei, P. A. Ward, and A. L. Beaudet. The role of P-selectin and ICAM-1 in acute lung injury as determined using blocking antibodies and mutant mice. J. Immunol. 157: 4609-4614, 1996.
9. Dore, M., R. J. Korthuis, D. N. Granger, M. L. Entman, and C. W. Smith. P-selectin mediates spontaneous leukocyte rolling in vivo. Blood 82: 1308-1316, 1993.
10. Entman, M. L., and C. M. Ballantyne. Inflammation in acute coronary syndromes. Circulation 88: 800-803, 1993.
11. Entman, M. L., L. H. Michael, R. D. Rossen, W. J. Dreyer, D. C. Anderson, and C. W. Smith. Inflammation in the course of early myocardial ischemia. FASEB J. 5: 2529-2537, 1991.
12. Eppihimer, M. J., and D. N. Granger. Ischemia/reperfusion-induced leukocyte-endothelial interactions in postcapillary venules. Shock 8: 16-25, 1997.
13. Eppihimer, M. J., J. Russell, D. C. Anderson, B. A. Wolitzky, and D. N. Granger. Endothelial cell adhesion molecule expression in gene-targeted mice. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H1903-H1908, 1997.
14. Eppihimer, M. J., B. Wolitzky, D. C. Anderson, M. A. Labow, and D. N. Granger. Heterogeneity of expression of E- and P-selectins in vivo. Circ. Res. 79: 560-569, 1996.
15. Flynn, D. M., A. J. Buda, P. R. Jeffords, and D. J. Lefer. A sialyl Lewis(x)-containing carbohydrate reduces infarct size: role of selectins in myocardial reperfusion injury. Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H2086-H2096, 1996.
16. Gill, E. A., Y. Kong, and L. D. Horwitz. An oligosaccharide sialyl-Lewis(x) analogue does not reduce myocardial infarct size after ischemia and reperfusion in dogs. Circulation 94: 542-546, 1996.
17. Hutter, J. J., R. Mestril, E. K. Tam, R. E. Sievers, W. H. Dillmann, and C. L. Wolfe. Overexpression of heat shock protein 72 in transgenic mice decreases infarct size in vivo. Circulation 94: 1408-1411, 1996.
18. Johnson, R. C., S. M. Chapman, Z. M. Dong, J. M. Ordovas, T. N. Mayadas, J. Herz, R. O. Hynes, E. J. Schaefer, and D. D. Wagner. Absence of P-selectin delays fatty streak formation in mice. J. Clin. Invest. 99: 1037-1043, 1997.
19. Kukielka, G. L., H. K. Hawkins, L. Michael, A. M. Manning, K. Youker, C. Lane, M. L. Entman, C. W. Smith, and D. C. Anderson. Regulation of intercellular adhesion molecule-1 (ICAM-1) in ischemic and reperfused canine myocardium. J. Clin. Invest. 92: 1504-1516, 1993.
20. Kukielka, G. L., K. A. Youker, H. K. Hawkins, J. L. Perrard, L. H. Michael, C. M. Ballantyne, C. W. Smith, and M. L. Entman. Regulation of ICAM-1 and IL-6 in myocardial ischemia: effect of reperfusion. Ann. NY Acad. Sci. 723: 258-270, 1994.
21. Kukielka, G. L., K. A. Youker, L. H. Michael, A. G. Kumar, C. M. Ballantyne, C. W. Smith, and M. L. Entman. Role of early reperfusion in the induction of adhesion molecules and cytokines in previously ischemic myocardium. Mol. Cell. Biochem. 147: 5-12, 1995.
22. Kumar, A., J. L. Hoover, C. A. Simmons, V. Lindner, and R. J. Shebuski. Remodeling and neointimal formation in the carotid artery of normal and P-selectin-deficient mice. Circulation 96: 4333-4342, 1997.
23. Lefer, A. M., A. S. Weyrich, and M. Buerke. Role of selectins, a new family of adhesion molecules, in ischaemia-reperfusion injury. Cardiovasc. Res. 28: 289-294, 1994.
24. Lefer, D. J., D. M. Flynn, and A. J. Buda. Effects of a monoclonal antibody directed against P-selectin after myocardial ischemia and reperfusion. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H88-H98, 1996.
25. x analog attenuates neutrophil accumulation and myocardial necrosis after ischemia and reperfusion. Circulation 90: 2390-2401, 1994.
26. Lorant, D. E., M. K. Topham, R. E. Whatley, R. P. McEver, T. M. McIntyre, S. M. Prescott, and G. A. Zimmerman. Inflammatory roles of P-selectin. J. Clin. Invest. 92: 559-570, 1993.
27. Lucchesi, B. R., S. W. Werns, and J. C. Fantone. The role of the neutrophil and free radicals in ischemic myocardial injury. J. Mol. Cell. Cardiol. 21: 1241-1251, 1989.
28. Mayadas, T. N., R. C. Johnson, H. Rayburn, R. O. Hynes, and D. D. Wagner. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell 74: 541-754, 1993.
29. Michael, L. H., M. L. Entman, C. J. Hartley, K. A. Youker, J. Zhu, S. R. Hall, H. K. Hawkins, K. Berens, and C. M. Ballantyne. Myocardial ischemia and reperfusion: a murine model. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H2147-H2154, 1995.
30. Murohara, T., M. Buerke, and A. M. Lefer. Polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction. Role of selectins. Arterioscler. Thromb. 14: 1509-1519, 1994.
31. Nageh, M. F., E. T. Sandberg, K. R. Marotti, A. H. Lin, E. P. Melchior, D. C. Bullard, and A. L. Beaudet. Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice. Arterioscler. Thromb. Vasc. Biol. 17: 1517-1520, 1997.
32. Nayler, W. G., and J. S. Elz. Reperfusion injury: laboratory artifact or clinical dilemma? Circulation 74: 215-221, 1986.
33. Reimer, K. A., J. E. Lowe, M. M. Rasmussen, and R. B. Jennings. The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs. duration of coronary occlusion in dogs. Circulation. 56: 786-794, 1977.
34. Sheridan, F. M., P. G. Cole, and D. Ramage. Leukocyte adhesion to the coronary microvasculature during ischemia and reperfusion in an in vivo canine model. Circulation 93: 1784-1787, 1996.
35. Silver, M. J., J. M. Sutton, S. Hook, P. Lee, J. L. Malycky, M. L. Phillips, S. G. Ellis, E. J. Topol, and F. A. Nicolini. Adjunctive selectin blockade successfully reduces infarct size beyond thrombolysis in the electrolytic canine coronary artery model. Circulation 92: 492-499, 1995.
36. Weyrich, A. S., X. Y. Ma, D. J. Lefer, K. H. Albertine, and A. M. Lefer. In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury. J. Clin. Invest. 91: 2620-2629, 1993.