Conjugated linoleic acid in bovine milk fat: A food-based approach to cancer chemoprevention

Trends in Food Science and Technology

Volumn 9, Issue 5, 1998, Pages 192-196

  O'Shea, M ^a   Lawless, F ^a   Stanton, C ^a   Devery, R ^b  

^a ANIMAL AND GRASSLAND RESEARCH AND INNOVATION CENTRE   (Ireland)

^b DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER; CHEMOPROPHYLAXIS; FOOD PRODUCT; LINOLEIC ACID;

EID: 0031715198     PISSN: 09242244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-2244(98)00036-3     Document Type: Review

References (45)

1. Morse M.A., Stoner G.D. Cancer chemoprevention: principles and prospects. in Carcinogenesis. 14:1993;1737-1746.
2. Parodi P.W. Conjugated linoleic acid: An anticarcinogenic fatty acid present in milk fat. in Australian J. Dairy Tech. 49:1994;93-97.
3. Ha Y.L., Grimm N.K., Pariza M.W. Newly recognised anticarcinogenic fatty acids: identification and quantification in natural and processed cheeses. in J. Agric. Food Chem. 37:1989;75-81.
4. Chin S.F., Liu W., Storkson J.M., Ha Y.L., Pariza M.W. Dietary sources of conjugated dienoic isomers of linoleic acid, a newly recognised class of anticarcinogens. in J. Food Comp. Anal. 5:1992;185-197.
5. Ip C., Chin S.F., Scimeca J.A., Pariza M.W. Mammary cancer prevention by conjugated dienoic derivative of linoleic acid. in Cancer Research. 51:1991;6118-6124.
6. Ha Y.L., Storkson J., Pariza M.W. Inhibition of Benzo(a)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid. in Cancer Research. 50:1990;1097-1101.
7. Belury M.A., Nickel K.P., Bird C.E., Wu Y. Dietary Conjugated linoleic acid modulation of phorbol ester skin tumour promotion. in Nutr. Cancer. 26:1996;149-157.
8. Ip C., Briggs S.P., Haegele A.D., Thompson H.J., Storkson J., Scimeca J.A. The efficacy of conjugated linoleic acid in mammary cancer prevention is independent of the level or type of fat in the diet. in Carcinogenesis. 17:1996;1045-1050.
9. Ip C., Jiang C., Thompson H.J., Scimeca J.A. Retention of conjugated linoleic acid in the mammary gland is associated with tumour inhibition during the post-initiation phase of carcinogenesis. in Carcinogenesis. 18:1997;755-759.
10. Ip C., Scimeca J.A. Conjugated linoleic acid and linoleic acid are distinctive modulators of mammary carcinogenesis. in Nutr. Cancer. 27:1997;131-135.
11. Liew C., Schut H.A.J., Chin S.F., Pariza M.W., Dashwood R.H. Protection of conjugated linoleic acids against 2-amino-3-methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms. in Carcinogenesis. 16:1995;3037-3043.
12. Scimeca, J.A., Thompson, H.J. and Ip, C. (1994) 'Effect of conjugated linoleic acid on carcinogenesis' in Diet and Breast Cancer. Plenum Press, New York.
13. Schut H.A.J., Cummings D.A., Smale M.H.E., Josyula S., Friesen M.D. DNA adducts of heterocyclic amines: formation, removal and inhibition by dietary components. in Mutation Research. 376:1997;185-194.
14. Nicolosi R.J., Rogers E.J., Kritchevsky D., Scimeca J.A., Huth P.J. Dietary conjugated linoleic acid reduces plasma lipoproteins and early aortic atherosclerosis in hypercholesterolaemic hamsters. in Artery. 22:1997;266-277.
15. Miller C.C., Park Y., Pariza M.W., Cook M.E. Feeding conjugated linoleic acid to animals partially overcomes catabolic responses due to endotoxin injection. in Biochemical and Biophysical Research Communications. 198:1994;1107-1112.
16. Fritsche, J. and Steinhart, H. (1998) 'Amounts of conjugated linoleic acid (CLA) in German foods and evaluation of daily intake ' in Z. Lebensm. Unters Forsch A,. 206, 77-82.
17. Ha Y.L., Grimm N.K., Pariza M.W. Anticarcinogens from ground beef: heat-altered derivatives of linoleic acid. in Carcinogenesis. 8:1987;1881-1887.
18. Garcia-Lopez S., Echeverria E., Tsui I., Balch B. Changes in the content of conjugated linoleic acid (CLA) in processed cheese during processing. in Food Res. Intl. 27:1994;61-64.
19. Shantha N.C., Decker E.A., Ustunol Z. Conjugated linoleic acid concentration in processed cheese. in J. Amer. Oil Chem. Soc. 69:1994;425-428.
20. Shantha N.C., Crum A.D., Decker E.A. Evaluation of conjugated linoleic acid concentrations in cooked beef. in J. Agric. Food. Chem. 42:1994;1757-1760.
21. Werner S.A., Luedecke L.O., Shultz T.D. Determination of conjugated linoleic acid content and isomer distribution in three Cheddar-type cheeses: Effects of cheese cultures, processing and aging. in J. Agric. Food Chem. 40:1992;1817-1821.
22. Lin H., Boylston T.D., Chang M.J., Luedecke L.O., Shultz T.D. Survey of the Conjugated Linoleic acid contents of dairy products. in J. Dairy Sci. 78:1995;2358-2365.
23. Jiang, J. (1998) 'Conjugated linoleic acid-occurence, oxidation and production by dairy starter cultures.' PhD Thesis, Swedish University of Agricultural Sciences, Uppsala, Sweden.
24. Stanton C., Lawless F., Kjellmer G., Harrington D., Devery R., Connolly J.F., Murphy J. Dietary influences on bovine milk cis-9, trans-11-conjugated linoleic acid content. in J. Food Sci. 62:1997;1083-1086.
25. Lawless, F., Murphy, J.J., Connolly, J.F., Devery, R. and Stanton, C. (1998) 'Elevation of bovine milk conjugated cis-9', trans-11-octadecadienoic acid by dietary supplementation: Effect of rapeseed and soybean supplements' in J. Dairy Sci. (in press).
26. Jiang J., Bjorck L., Fonden R. Occurrence of conjugated 9,11-octadecadienoic acid (CLA) in bovine milk: Effects of diet and feeding regime. in J. Dairy Sci. 79:1996;438.
27. Dhiman T.R., Anand G.R., Satter I.D., Pariza M.W. Conjugated linoleic acid content of milk from cows fed different diets. in J. Dairy Sci. 79:(Suppl. 1):1996;137.
28. Kelly, L.M. and Bauman, D.E. (1996) 'Conjugated linoleic acid: A potent anticarcinogen found in milk fat' Pages 68-74 in Proc. Cornell Nutr. Conf., Syracuse, NY Cornell Univ., Ithaca, NY.
29. Parodi P.W. Conjugated octadecadienoic acids of milk fat. in J. Dairy Sci. 60:1977;1550.
30. Stanton, C., Lawless, F., Murphy, J.J. and Connolly, J.F. (1997) 'Conjugated linoleic acid-a marketing advantage for animal fats' in Animal fats: BSE and After. (K. Berger ed.) P.J. Barnes and Associates, Bridgwater, UK, 27-41.
31. Riel R.R. Physico-chemical characteristics of Canadian milk fat. Unsaturated fatty acids. in J. Dairy Sci. 46:1963;102-106.
32. Parodi P.W. 'Cows' milk fat components as potential anticarcinogenic agents. in J. Nutr. 127:1997;1055-1060.
33. Ip C., Singh M., Thompson H.J., Scimeca A. Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat. in Cancer Research. 54:1994;1212-1215.
34. Schonberg S., Krokan H.E. The inhibitory effect of conjugated dienoic derivatives (CLA) of linoleic acid on thegrowth of human tumour cell lines is in part due to increased lipid peroxidation. in Anticancer Research. 15:1995;1241-1246.
35. desBordes C., Lea M.A. Effects of C18 fatty acid isomers on DNA synthesis in hepatoma and breast cancer cells. in Anticancer Research. 15:1995;2017-2022.
36. Durgam V.R., Fernandes G. The growth inhibitory effect of conjugated linoleic acid on MCF-7 cells is related to estrogen response system. in Cancer Lett. 116:1997;121-130.
37. Cunningham D.C., Harrison L.Y., Shultz T.D. Proliferative responses of normal human mammary and MCF-7 breast cancer cells to linoleic acid, conjugated linoleic acid and eicosanoid synthesis inhibitors in culture. in Anticancer Research. 17:1997;197-203.
38. Chew B.P., Wong T.S., Shultz T.D., Magnuson N.S. Effects of conjugated dienoic derivatives of linoleic acid and β -carotene in modulating lymphocyte and macrophage function. in Anticancer Research. 17:1997;1099-1106.
39. Murray, R. K. (1996) Harper's Biochemistry p.767 Prentice-Hall International, Inc.
40. Belury M.A., Kempa-Steczko A. Conjugated linoleic acid modulates hepatic lipid composition in mice. in Lipids. 32:1997;199-204.
41. Belury M.A., Moya-Camerena S.Y., Liu K.L., Vanden Heuvel J.P. Dietary conjugated linoleic acid induces peroxisome-specific enzyme accumulation and ornithine decarboxylase activity in mouse liver. in J. Nutr. Biochem. 8:1997;579-584.
42. De Voney D., Pariza M.W., Cook M.E. Conjugated linoleic acid increases blood and splenic T-cell response post lipopolysaccharide injection. in FASEB J. 9:1997;3355.
43. Dhiman T.R., Satter L.D., Pariza M.W., Galli M.P., Albright K. Conjugated linoleic acid (CLA) content of milk from cows offered diets rich in linoleic and linolenic acids. in J. Dairy Sci. 80:(Suppl. 1):1997;184.
44. Lawless, F., Stanton, C., L'Escop, P., Devery, R. and Murphy, J.J. (1998) 'The influence of breed on bovine milk cis-9, trans-11-conjugated linoleic acid content' in Livestock Production Sci. (submitted).
45. Shantha N.C., Ram L.N., O'Leary J., Hicks C.L., Decker E.A. Conjugated linoleic acid concentrations in dairy products as affected by processing and storage. in J. Food. Sci. 60:1995;695-697.