Characterisation of new efaroxan derivatives for use in purification of imidazoline-binding sites

European Journal of Pharmacology

Volumn 355, Issue 1, 1998, Pages 67-76

  Chan, Susan L F ^a   Pallett, Anna L ^a   Clews, John ^a   Ramsden, Christopher A ^a   Chapman, J C ^b   Kane, Charlotte ^b   Dunne, Mark J ^b   Morgan, Noel G ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Efaroxan; Endocrine pancreas; I site; Imidazoline; Insulin secretion; K(ATP) channel

Indexed keywords

2 (2 ETHYL 2,3 DIHYDROXYBENZO[B]FURAN 2 YL) 1H IMIDAZOLE; 2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; BENZOFURAN DERIVATIVE; EFAROXAN; IMIDAZOLINE RECEPTOR; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN MEMBRANE; CONTROLLED STUDY; INSULIN RELEASE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; BENZOFURANS; CELLS, CULTURED; FEMALE; IMIDAZOLES; ISLETS OF LANGERHANS; MALE; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, WISTAR; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031713515     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00466-X     Document Type: Article

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