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Volumn 19, Issue 3, 1998, Pages 527-534

Is DNA destiny? A cure for cystic fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

DNA; LIPOSOME; TRANSMEMBRANE CONDUCTANCE REGULATOR; VIRUS VECTOR;

EID: 0031713164     PISSN: 02725231     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0272-5231(05)70098-8     Document Type: Article
Times cited : (5)

References (42)
  • 1
    • 0031047239 scopus 로고    scopus 로고
    • Gene therapy for cystic fibrosis: Steady progress, should do well
    • E.W. Alton D. Geddes Gene therapy for cystic fibrosis: Steady progress, should do well Eur Respir J 10 1997 257 259
    • (1997) Eur Respir J , vol.10 , pp. 257-259
    • Alton, E.W.1    Geddes, D.2
  • 2
    • 0027361622 scopus 로고
    • Noninvasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
    • E.W. Alton F. Middleton P. Caplen Noninvasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice Nat Genet 5 1993 135 142
    • (1993) Nat Genet , vol.5 , pp. 135-142
    • Alton, E.W.1    Middleton, F.2    Caplen, P.3
  • 3
    • 0031041586 scopus 로고    scopus 로고
    • Effect of the E4 region on the persistence of transgene expression from adenovirus vectors
    • D. Armentano J. Zabner C. Sacks Effect of the E4 region on the persistence of transgene expression from adenovirus vectors J Virol 71 1997 2408 2416
    • (1997) J Virol , vol.71 , pp. 2408-2416
    • Armentano, D.1    Zabner, J.2    Sacks, C.3
  • 4
    • 16944367323 scopus 로고    scopus 로고
    • Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: A phase I clinical trial
    • G. Bellon L. Michel-Calemard D. Thouvenot Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: A phase I clinical trial Hum Gene Ther 8 1997 15 25
    • (1997) Hum Gene Ther , vol.8 , pp. 15-25
    • Bellon, G.1    Michel-Calemard, L.2    Thouvenot, D.3
  • 5
    • 0023764622 scopus 로고
    • Development of adenovirus vectors for the expression of heterologous genes
    • K. Berkner Development of adenovirus vectors for the expression of heterologous genes Biotechniques 6 1988 616 629
    • (1988) Biotechniques , vol.6 , pp. 616-629
    • Berkner, K.1
  • 6
    • 0028913411 scopus 로고
    • Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
    • N. Caplen E. Alton P. Middleton Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis Nat Med 1 1995 39 46
    • (1995) Nat Med , vol.1 , pp. 39-46
    • Caplen, N.1    Alton, E.2    Middleton, P.3
  • 7
    • 0029165356 scopus 로고
    • Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis
    • R.G. Crystal A. Mastrangeli A. Sanders Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis Hum Gene Ther 6 1995 667 703
    • (1995) Hum Gene Ther , vol.6 , pp. 667-703
    • Crystal, R.G.1    Mastrangeli, A.2    Sanders, A.3
  • 8
    • 0028168641 scopus 로고
    • Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
    • R.G. Crystal N.G. McElvaney M.A. Rosenfeld Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis Nat Genet 8 1994 42 71
    • (1994) Nat Genet , vol.8 , pp. 42-71
    • Crystal, R.G.1    McElvaney, N.G.2    Rosenfeld, M.A.3
  • 9
    • 0026951303 scopus 로고
    • Submucosal glands are the predominant site of CFTR expression in the human bronchus
    • J. Engelhardt J. Yankaskas S. Ernst Submucosal glands are the predominant site of CFTR expression in the human bronchus Nat Genet 2 1992 240 248
    • (1992) Nat Genet , vol.2 , pp. 240-248
    • Engelhardt, J.1    Yankaskas, J.2    Ernst, S.3
  • 10
    • 85119817370 scopus 로고    scopus 로고
    • FitzSimmons, S. Cystic Fibrosis Foundation Patient Registry Annual Data Report 1996. Bethesda, MD, 1997.
  • 11
    • 0027484584 scopus 로고
    • Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adenoassociated virus vector
    • T. Flotte S. Afione C. Conrad Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adenoassociated virus vector Proc Natl Acad Sci 90 1993 10613 10617
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 10613-10617
    • Flotte, T.1    Afione, S.2    Conrad, C.3
  • 12
    • 0028981979 scopus 로고
    • Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway
    • M. Goldman J.M. Wilson Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway J Virol 69 1995 5951 5958
    • (1995) J Virol , vol.69 , pp. 5951-5958
    • Goldman, M.1    Wilson, J.M.2
  • 13
    • 0030949875 scopus 로고    scopus 로고
    • Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
    • M. Goldman G. Anderson E. Stolzenberg Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis Cell 88 1997 553 560
    • (1997) Cell , vol.88 , pp. 553-560
    • Goldman, M.1    Anderson, G.2    Stolzenberg, E.3
  • 14
    • 0028802876 scopus 로고
    • Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector
    • J.G. Hay N.G. McElvaney J. Herena Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector Hum Gene Ther 6 1995 1487 1496
    • (1995) Hum Gene Ther , vol.6 , pp. 1487-1496
    • Hay, J.G.1    McElvaney, N.G.2    Herena, J.3
  • 15
    • 0001957609 scopus 로고
    • Adenoviridae and their replication
    • M. Horwitz Adenoviridae and their replication B. Fields Virology 1990 Raven Press New York 1679 1721
    • (1990) , pp. 1679-1721
    • Horwitz, M.1
  • 16
    • 0029177870 scopus 로고
    • Epitope tagging permits cell surface detection of functional CFTR
    • M. Howard M.D. DuVall D.C. Devor Epitope tagging permits cell surface detection of functional CFTR Am J Physiol 269 1995 C1565 C1576
    • (1995) Am J Physiol , vol.269 , pp. C1565-C1576
    • Howard, M.1    DuVall, M.D.2    Devor, D.C.3
  • 17
    • 0027475701 scopus 로고
    • Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
    • S. Hyde D. Gill C. Higgins Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy Nature 362 1993 250 255
    • (1993) Nature , vol.362 , pp. 250-255
    • Hyde, S.1    Gill, D.2    Higgins, C.3
  • 18
    • 0028912888 scopus 로고
    • Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells
    • L.G. Johnson S.E. Boyles J. Wilson Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells J Clin Invest 95 1995 1377 1382
    • (1995) J Clin Invest , vol.95 , pp. 1377-1382
    • Johnson, L.G.1    Boyles, S.E.2    Wilson, J.3
  • 19
    • 0029100239 scopus 로고
    • A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
    • M.R. Knowles K.W. Hohneker Z. Zhou A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis N Engl J Med 333 1995 823 831
    • (1995) N Engl J Med , vol.333 , pp. 823-831
    • Knowles, M.R.1    Hohneker, K.W.2    Zhou, Z.3
  • 20
    • 0028991826 scopus 로고
    • In vivo nasal potential difference: Techniques and protocols for assessing efficacy of gene transfer in cystic fibrosis
    • M.R. Knowles A.M. Paradiso R. Boucher In vivo nasal potential difference: Techniques and protocols for assessing efficacy of gene transfer in cystic fibrosis Hum Gene Ther 6 1995 445 455
    • (1995) Hum Gene Ther , vol.6 , pp. 445-455
    • Knowles, M.R.1    Paradiso, A.M.2    Boucher, R.3
  • 21
    • 0029318990 scopus 로고
    • Cell proliferation in bronchial epithelium and submucosal glands of cystic fibrosis patients
    • M. Leigh J. Kylander J. Yankaskas Cell proliferation in bronchial epithelium and submucosal glands of cystic fibrosis patients Am J Respir Cell Mol Biol 12 1995 605 612
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 605-612
    • Leigh, M.1    Kylander, J.2    Yankaskas, J.3
  • 22
    • 0029983685 scopus 로고    scopus 로고
    • “Sero-switch” adenovirus-mediated in vivo gene transfer: Circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype
    • A. Mastrangeli B. Harvey J. Yao “Sero-switch” adenovirus-mediated in vivo gene transfer: Circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype Hum Gene Ther 7 1996 79 87
    • (1996) Hum Gene Ther , vol.7 , pp. 79-87
    • Mastrangeli, A.1    Harvey, B.2    Yao, J.3
  • 23
    • 0028899392 scopus 로고
    • IL-6 release and airway administration of human CFTR cDNA adenovirus vector
    • N. McElvaney R. Crystal IL-6 release and airway administration of human CFTR cDNA adenovirus vector Nat Med 1 1995 182 184
    • (1995) Nat Med , vol.1 , pp. 182-184
    • McElvaney, N.1    Crystal, R.2
  • 24
    • 0030836678 scopus 로고    scopus 로고
    • Expression of integrin cell adhesion receptors during human airway epithelial repair in vivo
    • J.M. Pilewski J.D. Latoche S. Arcasoy Expression of integrin cell adhesion receptors during human airway epithelial repair in vivo Am J Physiol 273 1997 L256 L263
    • (1997) Am J Physiol , vol.273 , pp. L256-L263
    • Pilewski, J.M.1    Latoche, J.D.2    Arcasoy, S.3
  • 25
    • 8244245761 scopus 로고    scopus 로고
    • Evidence for safety and efficacy of DOTAP cationic lipsome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
    • D.J. Porteous J.R. Dorin G. McLachlan Evidence for safety and efficacy of DOTAP cationic lipsome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis Gene Ther 4 1997 210 218
    • (1997) Gene Ther , vol.4 , pp. 210-218
    • Porteous, D.J.1    Dorin, J.R.2    McLachlan, G.3
  • 26
    • 0027737463 scopus 로고
    • Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis
    • D. Rich L. Couture L. Cardoza Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis Hum Gene Ther 4 1993 461 476
    • (1993) Hum Gene Ther , vol.4 , pp. 461-476
    • Rich, D.1    Couture, L.2    Cardoza, L.3
  • 27
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA
    • J.R. Riordan J. Rommens B. Kerem Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA Science 245 1989 1066 1073
    • (1989) Science , vol.245 , pp. 1066-1073
    • Riordan, J.R.1    Rommens, J.2    Kerem, B.3
  • 28
    • 0024453308 scopus 로고
    • Identification of the cystic fibrosis gene: chromosome walking and jumping
    • J. Rommens M. Iannuzzi B. Kerem Identification of the cystic fibrosis gene: chromosome walking and jumping Science 245 1989 1059 1065
    • (1989) Science , vol.245 , pp. 1059-1065
    • Rommens, J.1    Iannuzzi, M.2    Kerem, B.3
  • 29
    • 0030026531 scopus 로고    scopus 로고
    • Gene therapy for cystic fibrosis
    • M. Rosenfeld F.S. Collins Gene therapy for cystic fibrosis Chest 109 1996 241 252
    • (1996) Chest , vol.109 , pp. 241-252
    • Rosenfeld, M.1    Collins, F.S.2
  • 30
    • 0030927585 scopus 로고    scopus 로고
    • CFTR gene transduction in neonatal rabbits using an adeno-associated virus vector
    • R. Rubinstein U. McVeigh T. Flotte CFTR gene transduction in neonatal rabbits using an adeno-associated virus vector Gene Ther 4 1997 384 392
    • (1997) Gene Ther , vol.4 , pp. 384-392
    • Rubinstein, R.1    McVeigh, U.2    Flotte, T.3
  • 31
    • 0027399681 scopus 로고
    • Adeno-associated virus: Integration at a specific chromosomal locus
    • R. Samulski Adeno-associated virus: Integration at a specific chromosomal locus Curr Opin Genet Dev 3 1993 74 80
    • (1993) Curr Opin Genet Dev , vol.3 , pp. 74-80
    • Samulski, R.1
  • 32
    • 0030746543 scopus 로고    scopus 로고
    • Antibody to CD40 ligand inhibits both humoral and cellular immune responses to adenoviral vectors and facilitates repeated administration to mouse airway
    • A. Scaria J. St George R. Gregory Antibody to CD40 ligand inhibits both humoral and cellular immune responses to adenoviral vectors and facilitates repeated administration to mouse airway Gene Ther 4 1997 611 617
    • (1997) Gene Ther , vol.4 , pp. 611-617
    • Scaria, A.1    St George, J.2    Gregory, R.3
  • 33
    • 0009625123 scopus 로고    scopus 로고
    • Repeated nasal administration of liposome-mediated CFTR gene transfer reagents: The clinical and immunological consequences
    • K.W. Southern S.C. Hyde E.M. Fitzjohn Repeated nasal administration of liposome-mediated CFTR gene transfer reagents: The clinical and immunological consequences Pediatr Pulmonol Suppl 14 1997 A209
    • (1997) Pediatr Pulmonol Suppl , vol.14 , pp. A209
    • Southern, K.W.1    Hyde, S.C.2    Fitzjohn, E.M.3
  • 34
    • 0029870085 scopus 로고    scopus 로고
    • Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
    • J. Smith S. Travis E. Greenberg Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid Cell 85 1996 229 236
    • (1996) Cell , vol.85 , pp. 229-236
    • Smith, J.1    Travis, S.2    Greenberg, E.3
  • 35
    • 0029618379 scopus 로고
    • Quantitative fluorescence measurements of chloride secretion in native airway epithelium from CF and non-CF subjects
    • M. Stern F.M. Munkonge N.J. Caplen Quantitative fluorescence measurements of chloride secretion in native airway epithelium from CF and non-CF subjects Gene Ther 2 1995 766 774
    • (1995) Gene Ther , vol.2 , pp. 766-774
    • Stern, M.1    Munkonge, F.M.2    Caplen, N.J.3
  • 36
    • 0028979812 scopus 로고
    • Effect of adenoviral vector infection on cell proliferation in cultured primary human airway epithelial cells
    • S. Teramoto L. Johnson W. Huang Effect of adenoviral vector infection on cell proliferation in cultured primary human airway epithelial cells Hum Gene Ther 6 1995 1045 1053
    • (1995) Hum Gene Ther , vol.6 , pp. 1045-1053
    • Teramoto, S.1    Johnson, L.2    Huang, W.3
  • 37
    • 85119802815 scopus 로고    scopus 로고
    • Efficient and persistent gene transfer of AAV-CFTR in the maxillary sinus of CF patients with antrostomies [abstr]
    • J. Wagner M. Moran A. Messner Efficient and persistent gene transfer of AAV-CFTR in the maxillary sinus of CF patients with antrostomies [abstr] Pediatr Pulmonol Suppl 14 1997 A216
    • (1997) Pediatr Pulmonol , Issue.Suppl 14 , pp. A216
    • Wagner, J.1    Moran, M.2    Messner, A.3
  • 38
    • 0028825747 scopus 로고
    • Gene therapy for cystic fibrosis: Challenges and future directions
    • J.M. Wilson Gene therapy for cystic fibrosis: Challenges and future directions J Clin Invest 96 1995 2547 2554
    • (1995) J Clin Invest , vol.96 , pp. 2547-2554
    • Wilson, J.M.1
  • 39
    • 0028937785 scopus 로고
    • Cellular and humoral immune response to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Y. Yang Q. Li H. Ertl Cellular and humoral immune response to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses J Virol 69 1995 2004 2015
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.3
  • 40
    • 0028328261 scopus 로고
    • Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
    • Y. Yang F. Nunes K. Berencsi Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy Proc Natl Acad Sci 91 1994 4407 4411
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 4407-4411
    • Yang, Y.1    Nunes, F.2    Berencsi, K.3
  • 41
    • 0030759153 scopus 로고    scopus 로고
    • Comparison of DNA–lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo
    • J. Zabner S.H. Cheng D. Meeker Comparison of DNA–lipid complexes and DNA alone for gene transfer to cystic fibrosis airway epithelia in vivo J Clin Invest 100 1997 1529 1537
    • (1997) J Clin Invest , vol.100 , pp. 1529-1537
    • Zabner, J.1    Cheng, S.H.2    Meeker, D.3
  • 42
    • 0027377523 scopus 로고
    • Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis
    • J. Zabner L.A. Couture R.J. Gregory Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis Cell 75 1993 207 216
    • (1993) Cell , vol.75 , pp. 207-216
    • Zabner, J.1    Couture, L.A.2    Gregory, R.J.3


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