Interleukin-10 down-regulates MHC class II αβ peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling

Immunity

Volumn 7, Issue 6, 1997, Pages 861-871

  Koppelman, Bruce ^a   Neefjes, Jacques J ^b   De Vries, Jan E ^c   De Waal Malefyt, René ^d  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c NOVARTIS RESEARCH INSTITUTE   (Austria)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN F(AB')2 FRAGMENT; IMMUNOGLOBULIN F(AB) FRAGMENT; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY;

ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; CELL MEMBRANE; DOWN REGULATION; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMBRANE VESICLE; MONOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0031406170     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80404-5     Document Type: Article

References (54)

1. Abrams, J.S., Roncarolo, M.-G., Yssel, H., Andersson, U., Gleich, G.J., and Silver, J.E. (1992). Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples, Immunol. Rev. 127, 5-24.
2. Barcy, S., Wettendorff, M., Leo, O., Urbain, J., Kruger, M., Ceuppens, J.L., and de Boer, M. (1995). FcR cross-linking on monocytes results in impaired T cell stimulatory capacity. Int. Immunol. 7, 179-189.
3. Barnstable, C.J., Bodmer, W.F., Brown, G., Galfre, G., Milstein, C., Williams, A.F., and Ziegler, A. (1978). Production of monoclonal anti-bodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell 14, 9-20.
4. Basham, T., and Merigan, T.C. (1983). Recombinant interferon-γ increases HLA-DR synthesis and expression. J. Immunol. 130, 1492-1494.
5. Bénaroch, P., Yilla, M., Raposo, G., Ito, K., Miwa, K., Geuze, H.J., and Ploegh, H.L. (1995). How MHC class II molecules reach the endocytic pathway. EMBO J. 14, 37-49.
6. Cella, M., Engering, A., Pinet, V., Pieters, J., and Lanzavecchia, A. (1997). Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature 388, 782-785.
7. Chin, J., and Kostura, M.J. (1993). Dissociation of IL-1 beta synthesis and secretion in human blood cell monocytes stimulated with bacterial cell wall products. J. Immunol. 151, 5574-5585.
8. Cresswell, P. (1994). Assembly, transport and function of MHC class II molecules. Annu. Rev. Immunol. 12, 259-293.
9. DeFrance, R., Vandervliet, B., Briere, F., Durand, I., Rousset, F., and Banchereau, J. (1992). Interleukin-10 and transforming growth factor β cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J. Exp. Med. 175, 671-682.
10. Denzin, L.K., and Cresswell, P. (1995). HLA-DM induces CLIP dissociation from MHC class II αβ dimers and facilitates peptide loading. Cell 82, 155-165.
11. de Waal Malefyt, R., Alarcon, B., Yssel, H., Sancho, J., Miyajima, A., Terhorst, C., Spits, H., and de Vries, J.E. (1989). Introduction of T cell receptor (TcR)-α cDNA has differential effects on TcR-γδ/CD3 expression by PEER and Lyon-1 cells. J. Immunol. 142, 3634-3642.
12. de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C.G., and de Vries, J.E. (1991a), Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174, 1209-1220.
13. de Waal Malefyt, R., Haanen, J., Spits, H., Roncarolo, M.-G., te Velde, A., Figdor, C., Johnson, K., Kastelein, R., Yssel, H., and de Vries, J.E. (1991b). IL-10 and viral IL-10 strongly reduce antigen specific human T cell proliferation by diminishing the antigen presenting capacity of monocytes via downregulation of class II MHC expression. J. Exp. Med. 174, 915-924.
14. de Waal Malefyt, R., Figdor, C.G., Huijbens, R., Mohan-Peterson, S., Bennett, B., Culpepper, J., Dang, W., Zurawski, G., and de Vries, J.E. (1993). Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes: comparison with IL-4 and modulation by IFN-gamma or IL-10. J. Immunol. 151, 6370-6381.
15. Feinberg, A.P., and Vogelstein, B. (1983). A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132, 6-13.
16. Finbloom, D.S., and Winestock, K.D. (1995). IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1α and STAT3 complexes in human T cells and monocytes. J. Immunol. 155, 1079-1090.
17. Frei, K., Lins, H., Schwerdel, C., and Fontana, A. (1994). Antigen presentation in the central nervous system: the inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and the type of cell analyzed. J. Immunol. 152, 2720-2728.
18. Germain, R.N., and Hendrix, L.R. (1991). MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature 353, 134-139.
19. Germain, R.N., and Rinker, A.J. (1993). Peptide binding inhibits protein aggregation of invariant-chain freeclass II dimers and promotes surface expression of occupied molecules. Nature 363, 725-728.
20. Groux, H., Bigler, M., de Vries, J.E., and Roncarolo, M.-G. (1996). Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells. J. Exp. Med. 184, 19-29.
21. Gruber, M.F., Williams, C.C., and Gerrard, T.L. (1994). Macrophage-colony-stimulating factor expression by anti-CD45 stimulated human monocytes is transcriptionally upregulated by IL-1 beta and inhibitted by IL-4 and IL-10. J. Immunol. 152, 1354-1361.
22. Guy, K., Van Heyningen, V., Cohen, B.B., Deane, D.L., and Steel, C.M. (1982). Differential expression and serologically distinct subpopulations of human la antigens detected with monoclonal anti-bodies to la alpha and beta chains. Eur. J. Immunol. 12, 942-948.
23. Koppelman, B., and Cresswell, P. (1990). Rapid nonlysosomal degradation of assembled HLA class II glycoproteins incorporating a mutant DR alpha-chain. J. Immunol. 145, 2730-2736.
24. Krangel, M.S., Orr, H.T., and Strominger, J.L. (1979). Assembly and maturation of HLA-A and HLA-B antigens in vivo. Cell 18, 979-991.
25. Kubin, M., Kamoun, M., and Trinchieri, G. (1994). Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells. J. Exp. Med. 180, 211-222.
26. Lampson, L.A., and Levy, R. (1980). Two populations of la-like molecules on a human B cell line. J. Immunol. 125, 293-299.
27. Liu, Y., Wei, S.H.-Y., Ho, A.S.-Y., de Waal Malefyt, R., and Moore, K. W. (1994). Expression cloning and characterization of a human IL-10 receptor. J. Immunol. 152, 1821-1829.
28. Machamer, C.E., and Cresswell, P. (1984). Monensin prevents terminal glycosylation of the N- and O-linked oligosaccharides of the HLA-DR-associated invariant chain and inhibits its dissociation from the alpha-beta chain complex. Proc. Natl. Acad. Sci. USA 81, 1287-1291.
29. MacNeil, I., Suda, T., Moore, K.W., Mossman, T.R., and Zlotnik, A. (1990). IL-10: a novel cytokine growth cofactor for mature and immature T cells. J. Immunol. 145, 4167-4173.
30. Matthes,T., Werner, F.C.,Tang, H., Zhang, X., Kindler, V., and Zubler, R.H. (1993). Cytokine mRNA expression during an in vitro response of human B lymphocytes: kinetics of B cell tumor necrosis factor alpha, interleukin (IL)6, IL-10, and transforming growth factor beta 1 mRNAs. J. Exp. Med. 178, 521-528.
31. Moore, K.W., O'Garra, A., de Waal Malefyt, R., Vieira, P., and Mosmann,T.R. (1993). Interleukin-10. Annu. Rev. Immunol. 11, 165-190.
32. Neefjes, J.J., and Ploegh, H.L. (1992). Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes. EMBO J. 11, 411-416.
33. Nowell, J., and Quaranta, V. (1985). Chloroquine affects biosynthesis of la molecules by inhibiting dissociation of invariant (γ) chains from α-β dimers in B cells. J. Exp. Med. 162, 1371-1376.
34. Péguet-Navarro, J., Moulon, C., Caux, C., Dalbiez-Gauthier, C., Banchereau, J., and Schmitt, D. (1994). Interleukin-10 inhibits the primary allogeneic T cell response to human epidermal Langerhan cells. Eur. J. Immunol. 24, 884-891.
35. Philips, J.H., Hori, T., Nagler, A., Bhat, N., Spits, H., and Lanier, L.L. (1992). Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3∈, δ proteins. J. Exp. Med. 175, 1055-1066.
36. Pierre, P., Turley, S.J., Gatti, E., Hull, M., Meltzer, J., Mirza, A., Inaba, K., Steinman, R., and Mellman, I. (1997). Developmental regulation of MHC class II transport in mouse dendritic cells. Nature 388, 787-792.
37. Pinet, V., Vergelli, M., Martin, R., Bakke, O., and Long, E.O. (1995). Antigen presentation mediated by recycling of surface HLA-DR molecules. Nature 375, 603-606.
38. Quaranta, V., Tanigaki, N., and Ferrone, S. (1981). Distribution of antigenic determinants recognized by three monoclonal antibodies (Q2/70, Q5/6, and Q5/13). Immunogenetics 12, 175-182.
39. Reid, P.A., and Watts, C. (1990). Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments. Nature 346, 655-657.
40. Rousset, F., Garcia, E., DeFrance, R., Peronne, C., Hsu, D.-H., Kastelein, R., Moore, K.W., and Banchereau, J. (1992). IL-10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. USA 89, 1890-1893.
41. Salazar-Onfray, F., Charo, J., Petersson, M., Frelands, S., Noffz, G., Qin, Z., Blankenstein, T., Ljungrren, H.-G., and Kiessling, R. (1997). Down-regulation of the expression and function of the transporter associated with antigen processing in murine tumor cell lines expressing IL-10. J. Immunol. 159, 3195-3202.
42. Sanderson, F., Kleijmeer, M.J., Kelly, A., Verwoerd, D., Tulp, A., Neefjes, J.J., Geuze, H.J., and Trowsdale, J. (1994). Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science 266, 1566-1569.
43. Shaw, S., Ziegler, A., and De Mars, R. (1985). Specificity of monoclonal antibodies directed against human and murine class II histocompatibility antigens as analyzed by binding to HLA-deletion mutant cell lines. Hum. Immunol. 12, 191-211.
44. Sherman, M.A., Weber, D.A., and Jensen, P.E. (1995). DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide. Immunity 3, 197-205.
45. Sloan, V.S., Cameron, P., Porter, G., Gammon, M., Amaya, M., Mellins, E., and Zaller, D.M. (1995). Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature 375, 802-806.
46. Smith, B.R., and Ault, K.A. (1981). Increase of surface la-like antigen expression on human monocytes independent of antigenic stimuli. J. Immunol. 727, 2020-2027.
47. te Velde, A.A., de Waal Malefijt, R., Huijbens, R.J., de Vries, J.E., and Figdor, G.G. (1992). IL-10 stimulates monocyte Fc-γR surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10. J Immunol 149, 4048-4052.
48. Thompson-Snipes, L., Dhar, V., Bond, M.W., Mosmann, T.R., Moore, K.W., and Rennick, D.M. (1991). Interleukin-10: a novel stimulatory factor for mast cells and their progenitors. J. Exp. Med. 173, 507-510.
49. Vieira, P., de Waal Malefyt, R., Dang, M.N., Johnson, K.E., Kastelein, R., Fiorentino, D.F., de Vries, J.E., Roncarolo, M.G., Mosmann, T. R., and Moore, K.W. (1991). Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proc. Natl. Acad. Sci. USA 88, 1172-1176.
50. Warmerdam, P.A.M., Long, E.O., and Roche, P.A. (1996). Isoforms of the invariant chain regulate transport of MHC class II molecules to antigen processing compartments. J. Cell Biol. 133, 281-291.
51. Willems, F., Marchant, A., Delville, J.P., Gerard, C., Delvaux, A., Velu, T., de Boer, M., and Goldman, M. (1994). Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes. Eur J Immunol 24, 1007-1009.
52. + T cell clones and peripheral blood T cells. J Immunol 149, 2378-2384.
53. Zeidler, R., Eissner, G., Meissner, P., Uebel, S., Tampé, R., Lazis, S., and Hammerschmidt, W. (1997). Downregulaton of TAP-1 in B lymphocytes by cellular and Epstein-Barr Virus-encoded interleukin-10. Blood 90, 2390-2397.
54. Zhong, G., Romagnoli, P., and Germain, R.N. (1997). Related leucine-based cytoplasmic targeting signals in invariant chain and major histocompatibility complex class II molecules controlendocytic presentation of distinct determinants in a single protein. J. Exp. Med. 185, 429-438.