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Volumn 14, Issue 8-9, 1998, Pages 914-924

Genetic epidemiology and molecular genetics of obesity: Results from the Quebec Family Study;L'epidemiologie genetique et la genetique moleculaire de l'obesite: Les enseignements de l'etude des familles de Quebec

Author keywords

[No Author keywords available]

Indexed keywords

AUTOSOMAL RECESSIVE INHERITANCE; CANADA; FAMILY STUDY; GENE SEGREGATION; GENETIC EPIDEMIOLOGY; GENETIC SUSCEPTIBILITY; HERITABILITY; HUMAN; MOLECULAR GENETICS; OBESITY; REVIEW;

EID: 0031707723     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.4267/10608/1163     Document Type: Review
Times cited : (15)

References (59)
  • 4
  • 5
    • 0030868010 scopus 로고    scopus 로고
    • Familial risk ratios for extreme obesty: Implications for mapping human obesity genes
    • Lee JH, Reed D, Price RA. Familial risk ratios for extreme obesty: implications for mapping human obesity genes. Int J Obes 1997; 21: 935-40.
    • (1997) Int J Obes , vol.21 , pp. 935-940
    • Lee, J.H.1    Reed, D.2    Price, R.A.3
  • 6
    • 0003928936 scopus 로고    scopus 로고
    • The genetics of obesity
    • Bouchard C, Bray G, James P, eds. New York: Dekker
    • Bouchard C, Pérusse L, Rice T, Rao DC. The genetics of obesity. In : Bouchard C, Bray G, James P, eds. Handbook of obesity. New York: Dekker, 1998: 157-90.
    • (1998) Handbook of Obesity , pp. 157-190
    • Bouchard, C.1    Pérusse, L.2    Rice, T.3    Rao, D.C.4
  • 7
    • 0027400507 scopus 로고
    • Genetic and nongenetic determinants of regional fat distribution
    • Bouchard C, Després JP, Mauriège P. Genetic and nongenetic determinants of regional fat distribution. Endocrinol Rev 1993 ; 14: 72-93.
    • (1993) Endocrinol Rev , vol.14 , pp. 72-93
    • Bouchard, C.1    Després, J.P.2    Mauriège, P.3
  • 8
    • 0009073989 scopus 로고    scopus 로고
    • Familial aggregation of subcutaneous fat patterning: Principal components of skinfolds in the Quebec Family Study
    • Li Z, Rice T, Pérusse L, Bouchard C, Rao DC. Familial aggregation of subcutaneous fat patterning: principal components of skinfolds in the Quebec Family Study. Am J Hum Biol 1996; 8: 535-42.
    • (1996) Am J Hum Biol , vol.8 , pp. 535-542
    • Li, Z.1    Rice, T.2    Pérusse, L.3    Bouchard, C.4    Rao, D.C.5
  • 9
    • 0029879773 scopus 로고    scopus 로고
    • Familial aggregation of abdominal visceral fat level : Results from the Quebec family study
    • Pérusse L, Després JP, Lemieux S, Rice T, Rao DC, Bouchard C. Familial aggregation of abdominal visceral fat level : results from the Quebec family study. Metabolism 1996; 45:378-82.
    • (1996) Metabolism , vol.45 , pp. 378-382
    • Pérusse, L.1    Després, J.P.2    Lemieux, S.3    Rice, T.4    Rao, D.C.5    Bouchard, C.6
  • 11
    • 0001618132 scopus 로고
    • Segregation analysis of bodv mass index in an unselected French-Canadian sample : The Quebec family study
    • Rice T, Borecki I, Bouchard C, Rao DC. Segregation analysis of bodv mass index in an unselected French-Canadian sample : the Quebec family study. Obes Res 1993; 2: 288-94.
    • (1993) Obes Res , vol.2 , pp. 288-294
    • Rice, T.1    Borecki, I.2    Bouchard, C.3    Rao, D.C.4
  • 12
    • 0027496291 scopus 로고
    • Segregation analysis of fat mass and other body composition measures derived from underwater weighing
    • Rice T, Borecki IB, Bouchard C, Rao DC. Segregation analysis of fat mass and other body composition measures derived from underwater weighing. Am J Hum Genet 1993; 52: 967-73.
    • (1993) Am J Hum Genet , vol.52 , pp. 967-973
    • Rice, T.1    Borecki, I.B.2    Bouchard, C.3    Rao, D.C.4
  • 13
    • 0027489732 scopus 로고
    • Influence of genotype-dependent effects of covariates on the outcome of segregation analysis of the body mass index
    • Borecki IB, Bonney GE, Rice T, Bouchard C, Rao DC. Influence of genotype-dependent effects of covariates on the outcome of segregation analysis of the body mass index. Am J Hum Genet 1993; 53: 676-87.
    • (1993) Am J Hum Genet , vol.53 , pp. 676-687
    • Borecki, I.B.1    Bonney, G.E.2    Rice, T.3    Bouchard, C.4    Rao, D.C.5
  • 14
    • 0029193955 scopus 로고
    • Major gene influence on the propensity to store fat in trunk versus extremity depots : Evidence from the Quebec Family Study
    • Borecki I, Rice T, Pérusse L, Bouchard C, Rao DC. Major gene influence on the propensity to store fat in trunk versus extremity depots : evidence from the Quebec Family Study. Obes Res 1995; 3: 1-8.
    • (1995) Obes Res , vol.3 , pp. 1-8
    • Borecki, I.1    Rice, T.2    Pérusse, L.3    Bouchard, C.4    Rao, D.C.5
  • 17
    • 0030147124 scopus 로고    scopus 로고
    • Familial clustering of abdominal visceral fat and total fat mass: The Quebec Family Study
    • Rice T, Pérusse L, Bouchard C, Rao DC. Familial clustering of abdominal visceral fat and total fat mass: the Quebec Family Study. Obes Res 1996: 4: 253-61.
    • (1996) Obes Res , vol.4 , pp. 253-261
    • Rice, T.1    Pérusse, L.2    Bouchard, C.3    Rao, D.C.4
  • 20
    • 0028126685 scopus 로고
    • Cross-trait familial resemblance for body fat and blood pressure : Familial correlations in the Quebec family study
    • Rice T, Province M, Pérusse L, Bouchard C, Rao DC. Cross-trait familial resemblance for body fat and blood pressure : familial correlations in the Quebec family study. Am J Hum Genet 1994; 55: 1019-29.
    • (1994) Am J Hum Genet , vol.55 , pp. 1019-1029
    • Rice, T.1    Province, M.2    Pérusse, L.3    Bouchard, C.4    Rao, D.C.5
  • 21
    • 0029658549 scopus 로고    scopus 로고
    • Familial correlations in the Quebec Family Study: Cross-trait familial resemblance for body fat with plasma glucose and insulin
    • Rice T, Nadeau A, Pérusse L, Bouchard C. Rao DC. Familial correlations in the Quebec Family Study: cross-trait familial resemblance for body fat with plasma glucose and insulin. Diabetologia 1996; 39: 1357-64
    • (1996) Diabetologia , vol.39 , pp. 1357-1364
    • Rice, T.1    Nadeau, A.2    Pérusse, L.3    Bouchard, C.4    Rao, D.C.5
  • 22
    • 0031470526 scopus 로고    scopus 로고
    • Cross-trait familial resemblance for body fat and blood lipids : Familial correlations in the Quebec Family Study
    • Pérusse L, Rice T, Després JP, Bouchard C, Rao DC. Cross-trait familial resemblance for body fat and blood lipids : familial correlations in the Quebec Family Study. Arterioscler Thromb Vasc Biol 1997; 17: 3270-7.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3270-3277
    • Pérusse, L.1    Rice, T.2    Després, J.P.3    Bouchard, C.4    Rao, D.C.5
  • 23
    • 0031612168 scopus 로고    scopus 로고
    • The human obesity gene map: The 1997 update
    • Chagnon YC, Pérusse L, Bouchard C. The human obesity gene map: the 1997 update. Obes Res 1998; 6: 76-92.
    • (1998) Obes Res , vol.6 , pp. 76-92
    • Chagnon, Y.C.1    Pérusse, L.2    Bouchard, C.3
  • 24
    • 0019858521 scopus 로고
    • Isoelectric focusing of red cell phosphoglucomutase (E.C.: 2.7.5.1) at the PGM1 locus in a French-Canadian population
    • Chagnon YC, Bouchard C, Allard C. Isoelectric focusing of red cell phosphoglucomutase (E.C.: 2.7.5.1) at the PGM1 locus in a French-Canadian population. Hum Genet 1981; 59: 36-8.
    • (1981) Hum Genet , vol.59 , pp. 36-38
    • Chagnon, Y.C.1    Bouchard, C.2    Allard, C.3
  • 25
    • 0022920947 scopus 로고
    • Esterase D polymorphism in a French-Canadian population
    • Couture L, Chagnon M, Allard C, Bouchard C. Esterase D polymorphism in a French-Canadian population. Hum Genet 1986; 73: 276.
    • (1986) Hum Genet , vol.73 , pp. 276
    • Couture, L.1    Chagnon, M.2    Allard, C.3    Bouchard, C.4
  • 26
    • 0023149031 scopus 로고
    • Adenosine deaminase, adenylate kinase and acid phosphatase polymorphisms in a French-Canadian population
    • Couture L, Chagnon M, Allard C, Bouchard C. Adenosine deaminase, adenylate kinase and acid phosphatase polymorphisms in a French-Canadian population. Hum Genet 1987; 75: 188.
    • (1987) Hum Genet , vol.75 , pp. 188
    • Couture, L.1    Chagnon, M.2    Allard, C.3    Bouchard, C.4
  • 27
    • 0000082145 scopus 로고
    • An exploratory investigation of genetic linkage with body composition and fatness phenotypes : The Quebec Family Study
    • Borecki IB, Rice T, Pérusse L, Bouchard C, Rao DC. An exploratory investigation of genetic linkage with body composition and fatness phenotypes : the Quebec Family Study. Obes Res 1994 ; 2: 213-9.
    • (1994) Obes Res , vol.2 , pp. 213-219
    • Borecki, I.B.1    Rice, T.2    Pérusse, L.3    Bouchard, C.4    Rao, D.C.5
  • 28
    • 0028203814 scopus 로고
    • DNA variation in the genes of the Na,K-adenosine triphosphatase and its relation with resting metabolic rate, respiratory quotient, and body fat
    • Dériaz O, Dionne FT, Pérusse L, Tremblay A, Vohl MC, Côté G, Bouchard C. DNA variation in the genes of the Na,K-adenosine triphosphatase and its relation with resting metabolic rate, respiratory quotient, and body fat. J Clin Invest 1994 ; 93: 838-43.
    • (1994) J Clin Invest , vol.93 , pp. 838-843
    • Dériaz, O.1    Dionne, F.T.2    Pérusse, L.3    Tremblay, A.4    Vohl, M.C.5    Côté, G.6    Bouchard, C.7
  • 31
    • 0030610680 scopus 로고    scopus 로고
    • Familial aggregation of obesity, candidate genes and quantitative trait loci
    • Chagnon YC, Pérusse L, Bouchard C. Familial aggregation of obesity, candidate genes and quantitative trait loci. Curr Opin Lipidol 1997;8: 205-11.
    • (1997) Curr Opin Lipidol , vol.8 , pp. 205-211
    • Chagnon, Y.C.1    Pérusse, L.2    Bouchard, C.3
  • 32
    • 0031436966 scopus 로고    scopus 로고
    • Human beta-2 adrenoreceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoreceptor function
    • Large V, Hellström L, Revnisdottir S, Lönnqvist F, Eriksson P, Lannfaelt L, Arner P. Human beta-2 adrenoreceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoreceptor function. J Clin Res 1997; 100: 3005-13.
    • (1997) J Clin Res , vol.100 , pp. 3005-3013
    • Large, V.1    Hellström, L.2    Revnisdottir, S.3    Lönnqvist, F.4    Eriksson, P.5    Lannfaelt, L.6    Arner, P.7
  • 35
    • 0030729552 scopus 로고    scopus 로고
    • Linkage between markers in the vicinity of the uncoupling protein 2 gene and resting metabolic rate in humans
    • Bouchard C, Pérusse L, Chagnon YC, Warden C, Ricquier D. Linkage between markers in the vicinity of the uncoupling protein 2 gene and resting metabolic rate in humans. Hum Mol Genet 1997; 6: 1887-9.
    • (1997) Hum Mol Genet , vol.6 , pp. 1887-1889
    • Bouchard, C.1    Pérusse, L.2    Chagnon, Y.C.3    Warden, C.4    Ricquier, D.5
  • 36
    • 0030803678 scopus 로고    scopus 로고
    • The human uncoupling protein-3. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts
    • Solanes G. Vidal-Puig A, Grujic D, Flier JS, Lowell BB. The human uncoupling protein-3. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts. J Biol Chem. 1997; 272: 25433-6.
    • (1997) J Biol Chem. , vol.272 , pp. 25433-25436
    • Solanes, G.1    Vidal-Puig, A.2    Grujic, D.3    Flier, J.S.4    Lowell, B.B.5
  • 37
    • 0027957842 scopus 로고
    • Detection of a Msp I restriction length polymorphism for the human sex hormone-binding globulin (SHBG) gene
    • Vohl MC, Dionne FT, Dériaz O, Chagnon M, Bouchard C. Detection of a Msp I restriction length polymorphism for the human sex hormone-binding globulin (SHBG) gene. Hum Genet 1994; 93: 84.
    • (1994) Hum Genet , vol.93 , pp. 84
    • Vohl, M.C.1    Dionne, F.T.2    Dériaz, O.3    Chagnon, M.4    Bouchard, C.5
  • 38
    • 0040920294 scopus 로고
    • Relation between BgIII polymorphism in 3β-hydroxysteroid dehydrogenase gene and adipose tissue distribution in humans
    • Vohl MC, Dionne FT, Pérusse L, Dériaz O, Chagnon M, Bouchard C. Relation between BgIII polymorphism in 3β-hydroxysteroid dehydrogenase gene and adipose tissue distribution in humans. Obes Res 1994; 2: 444-9.
    • (1994) Obes Res , vol.2 , pp. 444-449
    • Vohl, M.C.1    Dionne, F.T.2    Pérusse, L.3    Dériaz, O.4    Chagnon, M.5    Bouchard, C.6
  • 41
    • 0026615126 scopus 로고
    • An association between a Bcll restriction fragment length polymorphism of the glucocorticoid receptor locus and hyperinsulinaemia in obese women
    • Weaver JU, Hitman GA, Kopelman PG. An association between a Bcll restriction fragment length polymorphism of the glucocorticoid receptor locus and hyperinsulinaemia in obese women. J Mol Endocrinol 1992; 9: 295-300.
    • (1992) J Mol Endocrinol , vol.9 , pp. 295-300
    • Weaver, J.U.1    Hitman, G.A.2    Kopelman, P.G.3
  • 45
    • 0029821904 scopus 로고    scopus 로고
    • Thompson DB, Bogardus C, Ravussin E. Absence of linkage of obesity and energy metabolism to markers flanking homologues of rodent obesity genes in Pima Indians
    • Norman RA, Leibel RL, Chung WK, Power-Kehoe L, Chua SC Jr, Knowler WC. Thompson DB, Bogardus C, Ravussin E. Absence of linkage of obesity and energy metabolism to markers flanking homologues of rodent obesity genes in Pima Indians. Diabetes 1996; 45: 1229-32.
    • (1996) Diabetes , vol.45 , pp. 1229-1232
    • Norman, R.A.1    Leibel, R.L.2    Chung, W.K.3    Power-Kehoe, L.4    Chua Jr., S.C.5    Knowler, W.C.6
  • 46
    • 0029401938 scopus 로고
    • Absence of linkage between human obesity and the mouse Agouti homologous region (2Oq 11.2) or other markers spanning chromosome 2Oq
    • Xu W, Reed DR, Ding Y, Price RA. Absence of linkage between human obesity and the mouse Agouti homologous region (2Oq 11.2) or other markers spanning chromosome 2Oq. Obes Res 1995; 3: 559-62
    • (1995) Obes Res , vol.3 , pp. 559-562
    • Xu, W.1    Reed, D.R.2    Ding, Y.3    Price, R.A.4
  • 47
    • 0031455342 scopus 로고    scopus 로고
    • Linkage and association studies between the Melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Quebec Family Study
    • Chagnon YC, Chen WJ, Pérusse L, Chagnon M, Nadeau A, Wilkison WO, Bouchard C. Linkage and association studies between the Melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Quebec Family Study. Mol Med 1997; 3: 663-73.
    • (1997) Mol Med , vol.3 , pp. 663-673
    • Chagnon, Y.C.1    Chen, W.J.2    Pérusse, L.3    Chagnon, M.4    Nadeau, A.5    Wilkison, W.O.6    Bouchard, C.7
  • 48
    • 16944362008 scopus 로고    scopus 로고
    • Genomewide search for genes influencing percent body fat in Pima Indians: Suggestive linkage at chromosome 11q21-q22
    • Norman RA, Thompson DB, Foroud T, Garvey WT, Bennett PH, Bogardus C, Ravussin E, and other members of the Pima Diabetes Gene Group. Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Am J Hum Genet 1997; 60: 166-73.
    • (1997) Am J Hum Genet , vol.60 , pp. 166-173
    • Norman, R.A.1    Thompson, D.B.2    Foroud, T.3    Garvey, W.T.4    Bennett, P.H.5    Bogardus, C.6    Ravussin, E.7
  • 50
    • 0019434793 scopus 로고
    • Genetic analysis of the Stanford LRC Family Study data: I. Structured exploratory data analysis of height and weight measurements
    • Karlin S, Williams PT, Jensen S, Farquhar JW. Genetic analysis of the Stanford LRC Family Study data: I. Structured exploratory data analysis of height and weight measurements. Am J Epidemiol 1981 ; 113: 307-24.
    • (1981) Am J Epidemiol , vol.113 , pp. 307-324
    • Karlin, S.1    Williams, P.T.2    Jensen, S.3    Farquhar, J.W.4
  • 53
    • 0031019654 scopus 로고    scopus 로고
    • Segregation analysis of fat mass and fat-free mass with age- and sex-dependent effects: The Stanislas family study
    • Lecomte E, Herbeth B, Nicaud V, Rakotovao R, Artur Y, Tiret L. Segregation analysis of fat mass and fat-free mass with age- and sex-dependent effects: the Stanislas family study. Genet Epidemiol 1997; 14: 51-62.
    • (1997) Genet Epidemiol , vol.14 , pp. 51-62
    • Lecomte, E.1    Herbeth, B.2    Nicaud, V.3    Rakotovao, R.4    Artur, Y.5    Tiret, L.6
  • 54
    • 0001207423 scopus 로고
    • Strong evidence for a major gene for obesity in the large, unselected, total community health study of Tecumseh
    • Province MA, Arnqvist P, Keller J, Higgins M, Rao DC. Strong evidence for a major gene for obesity in the large, unselected, total community health study of Tecumseh. Am J Hum Genet 1090; 47(suppl) : A143.
    • (1990) Am J Hum Genet , vol.47 , Issue.SUPPL.
    • Province, M.A.1    Arnqvist, P.2    Keller, J.3    Higgins, M.4    Rao, D.C.5
  • 56
    • 0025085568 scopus 로고
    • Common major gene inheritance of extreme overweight
    • Price RA. Ness R, Laskarzewski P. Common major gene inheritance of extreme overweight. Hum Biol 1990; 62: 747-65.
    • (1990) Hum Biol , vol.62 , pp. 747-765
    • Price, R.A.1    Ness, R.2    Laskarzewski, P.3
  • 57
    • 0026345880 scopus 로고
    • The genetic and environmental sources of body mass index variability: The muscatine ponderosity family study
    • Moll PP, Burns TL, Lauer RM. The genetic and environmental sources of body mass index variability: the muscatine ponderosity family study. Am J Hum Genet 1991 ; 49: 1243-55.
    • (1991) Am J Hum Genet , vol.49 , pp. 1243-1255
    • Moll, P.P.1    Burns, T.L.2    Lauer, R.M.3
  • 58
    • 0026061561 scopus 로고
    • Inheritance of extreme overweight in black families
    • Ness R, Laskarzewski P, Price RA. Inheritance of extreme overweight in black families. Hum Biol 1991 ;63: 39-52.
    • (1991) Hum Biol , vol.63 , pp. 39-52
    • Ness, R.1    Laskarzewski, P.2    Price, R.A.3
  • 59
    • 0031612168 scopus 로고    scopus 로고
    • The human obesity gene map: The 1997 update
    • Chagnon YC, Pérusse L, Bouchard C. The human obesity gene map: the 1997 update, Obes Res 1998; 6: 76-92.
    • (1998) Obes Res , vol.6 , pp. 76-92
    • Chagnon, Y.C.1    Pérusse, L.2    Bouchard, C.3


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