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Volumn 31, Issue 1, 1998, Pages 89-104

Induction of cell-mediated immunity during early stages of infection with intracellular protozoa

Author keywords

Cytokines; Leishmania; Macrophages; Nitric oxide; Toxoplasma gondii; Trypanosoma cruzi

Indexed keywords

PROTOZOA; TOXOPLASMA GONDII; TRYPANOSOMA; TRYPANOSOMA CRUZI; VERTEBRATA;

EID: 0031609199     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X1998000100012     Document Type: Article
Times cited : (28)

References (105)
  • 1
    • 0023724505 scopus 로고
    • Pathophysiology of toxoplasmosis
    • Frenkel JK (1988). Pathophysiology of toxoplasmosis. Parasitology Today, 4: 273-278.
    • (1988) Parasitology Today , vol.4 , pp. 273-278
    • Frenkel, J.K.1
  • 2
  • 3
    • 0027382381 scopus 로고
    • Host resistance to Toxoplasma gondii: A model for studying the selective induction of cell-mediated immunity by intracellular parasites
    • Gazzinelli RT, Denkers EY & Sher A (1993). Host resistance to Toxoplasma gondii: a model for studying the selective induction of cell-mediated immunity by intracellular parasites. Infectious Agents and Disease, 2: 139-149.
    • (1993) Infectious Agents and Disease , vol.2 , pp. 139-149
    • Gazzinelli, R.T.1    Denkers, E.Y.2    Sher, A.3
  • 6
    • 0030010929 scopus 로고    scopus 로고
    • IL-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes
    • Aliberti JCS, Cardoso MAG, Martins GA, Gazzinelli RT, Vieira LQ & Silva JS (1996). IL-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes. Infection and Immunity, 64: 1961-1967.
    • (1996) Infection and Immunity , vol.64 , pp. 1961-1967
    • Aliberti, J.C.S.1    Cardoso, M.A.G.2    Martins, G.A.3    Gazzinelli, R.T.4    Vieira, L.Q.5    Silva, J.S.6
  • 7
    • 0028051548 scopus 로고
    • Nitric oxide is involved in the control of Trypanosoma cruzi-induced parasitemia and directly kills parasite in vitro
    • Vespa GNR, Cunha FQ & Silva JS (1994). Nitric oxide is involved in the control of Trypanosoma cruzi-induced parasitemia and directly kills parasite in vitro. Infection and Immunity, 62: 5177-5182.
    • (1994) Infection and Immunity , vol.62 , pp. 5177-5182
    • Vespa, G.N.R.1    Cunha, F.Q.2    Silva, J.S.3
  • 9
    • 0026536194 scopus 로고
    • Susceptibility of β2-microglobulin-deficient mice to Trypanosoma cruzi infection
    • Tarleton RL, Koller BH, Latour A & Postan M (1992). Susceptibility of β2-microglobulin-deficient mice to Trypanosoma cruzi infection. Nature, 356: 338-340.
    • (1992) Nature , vol.356 , pp. 338-340
    • Tarleton, R.L.1    Koller, B.H.2    Latour, A.3    Postan, M.4
  • 10
    • 0023183276 scopus 로고
    • Suppression of polyclonal antibody production in murine Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies
    • Minoprio P, Eisen H, Joskowicz M, Pereira P & Coutinho A (1987). Suppression of polyclonal antibody production in murine Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies. Journal of Immunology, 139: 545-550.
    • (1987) Journal of Immunology , vol.139 , pp. 545-550
    • Minoprio, P.1    Eisen, H.2    Joskowicz, M.3    Pereira, P.4    Coutinho, A.5
  • 11
    • 0017225232 scopus 로고
    • Protective effects of specific antibodies in Trypanosoma cruzi infections
    • Krettli AU & Brener Z (1976). Protective effects of specific antibodies in Trypanosoma cruzi infections. Journal of Immunology, 116: 755-760.
    • (1976) Journal of Immunology , vol.116 , pp. 755-760
    • Krettli, A.U.1    Brener, Z.2
  • 13
    • 0022569904 scopus 로고
    • Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: Clinical and neuropathologic findings in 27 patients
    • Navia BA, Petito CK, Gold JWM, Cho ES, Jordan BD & Price RW (1986). Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathologic findings in 27 patients. Annals of Neurology, 19: 224-238.
    • (1986) Annals of Neurology , vol.19 , pp. 224-238
    • Navia, B.A.1    Petito, C.K.2    Gold, J.W.M.3    Cho, E.S.4    Jordan, B.D.5    Price, R.W.6
  • 16
    • 0026673841 scopus 로고
    • Inhibition of macrophage protein kinase C-mediated protein phosphorylation by Leishmania donovani lipophosphoglycan
    • Descoteaux A, Matlashewski G & Turco SJ (1992). Inhibition of macrophage protein kinase C-mediated protein phosphorylation by Leishmania donovani lipophosphoglycan. Journal of Immunology, 149: 3008-3015.
    • (1992) Journal of Immunology , vol.149 , pp. 3008-3015
    • Descoteaux, A.1    Matlashewski, G.2    Turco, S.J.3
  • 17
    • 0027284773 scopus 로고
    • Alteration of Leishmania donovani infection levels by selective impairment of macrophage signal transduction
    • Moore KJ, Labrecque S & Matlashewski G (1993). Alteration of Leishmania donovani infection levels by selective impairment of macrophage signal transduction. Journal of Immunology, 150: 4457-4465.
    • (1993) Journal of Immunology , vol.150 , pp. 4457-4465
    • Moore, K.J.1    Labrecque, S.2    Matlashewski, G.3
  • 18
    • 0028158318 scopus 로고
    • Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4(+) T cells during initiation of infection
    • Reiner SL, Zheng SC, Wang ZE, Stowring L & Locksley RM (1994). Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4(+) T cells during initiation of infection. Journal of Experimental Medicine, 179: 447-456.
    • (1994) Journal of Experimental Medicine , vol.179 , pp. 447-456
    • Reiner, S.L.1    Zheng, S.C.2    Wang, Z.E.3    Stowring, L.4    Locksley, R.M.5
  • 19
    • 0030021084 scopus 로고    scopus 로고
    • Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
    • Carrera L, Gazzinelli RT, Badolato R, Hieny S, Müller W, Kühn R & Sacks DL (1996). Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice. Journal of Experimental Medicine, 183: 515-526.
    • (1996) Journal of Experimental Medicine , vol.183 , pp. 515-526
    • Carrera, L.1    Gazzinelli, R.T.2    Badolato, R.3    Hieny, S.4    Müller, W.5    Kühn, R.6    Sacks, D.L.7
  • 20
    • 0028935560 scopus 로고
    • Glycoinositolphospholipids of Leishmania major inhibit nitric oxide synthesis and reduce leishmanicidal activity in murine macrophages
    • Proudfoot L, O'Donnell CA & Liew FY (1995). Glycoinositolphospholipids of Leishmania major inhibit nitric oxide synthesis and reduce leishmanicidal activity in murine macrophages. European Journal of Immunology, 25: 745-750.
    • (1995) European Journal of Immunology , vol.25 , pp. 745-750
    • Proudfoot, L.1    O'Donnell, C.A.2    Liew, F.Y.3
  • 21
    • 0024412797 scopus 로고
    • Administration of monoclonal anti-IFN-γ antibodies in vivo abrogates natural resistance of H/HeN mice to infection with Leishmania major
    • Belosevic M, Finbloom DS, Van der Meide PH, Slayter MV & Nacy CA (1989). Administration of monoclonal anti-IFN-γ antibodies in vivo abrogates natural resistance of H/HeN mice to infection with Leishmania major. Journal of Immunology, 143: 266-274.
    • (1989) Journal of Immunology , vol.143 , pp. 266-274
    • Belosevic, M.1    Finbloom, D.S.2    Van Der Meide, P.H.3    Slayter, M.V.4    Nacy, C.A.5
  • 23
    • 0031570514 scopus 로고    scopus 로고
    • GPI-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of pro-inflammatory cytokines by macrophages
    • Camargo MM, Almeida IC, Pereira MES, Ferguson MAJ, Travassos LR & Gazzinelli RT (1997). GPI-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of pro-inflammatory cytokines by macrophages. Journal of Immunology, 158: 5890-5901.
    • (1997) Journal of Immunology , vol.158 , pp. 5890-5901
    • Camargo, M.M.1    Almeida, I.C.2    Pereira, M.E.S.3    Ferguson, M.A.J.4    Travassos, L.R.5    Gazzinelli, R.T.6
  • 24
    • 0027264849 scopus 로고
    • Interleukin 12 is required for the T-lymphocyte independent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzinelli RT, Hieny S, Wynn T, Wolf S & Sher A (1993). Interleukin 12 is required for the T-lymphocyte independent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proceedings of the National Academy of Sciences, USA, 90: 6115-6119.
    • (1993) Proceedings of the National Academy of Sciences, USA , vol.90 , pp. 6115-6119
    • Gazzinelli, R.T.1    Hieny, S.2    Wynn, T.3    Wolf, S.4    Sher, A.5
  • 27
    • 0027208743 scopus 로고
    • Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-α and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation
    • Gazzinelli RT, Eltoum I, Wynn TA & Sher A (1993). Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-α and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation. Journal of Immunology, 151: 3672-3681.
    • (1993) Journal of Immunology , vol.151 , pp. 3672-3681
    • Gazzinelli, R.T.1    Eltoum, I.2    Wynn, T.A.3    Sher, A.4
  • 29
    • 0031573627 scopus 로고    scopus 로고
    • Glycoconjugates isolated from Trypanosoma uzi but not from Leismania species membranes trigger nitric oxide synthesis as well as microbicidal activity in IFN-γ-primed macrophages
    • In press
    • Camargo MM, Andrade AC, Almeida IC, Travassos LR & Gazzinelli RT (1997). Glycoconjugates isolated from Trypanosoma uzi but not from Leismania species membranes trigger nitric oxide synthesis as well as microbicidal activity in IFN-γ-primed macrophages. Journal of Immonology (In press).
    • (1997) Journal of Immonology
    • Camargo, M.M.1    Andrade, A.C.2    Almeida, I.C.3    Travassos, L.R.4    Gazzinelli, R.T.5
  • 32
    • 0030980385 scopus 로고    scopus 로고
    • Regulation of interleukin-12 by complement receptor 3 signalling
    • in press
    • Marth T & Kelsall BL (1997). Regulation of interleukin-12 by complement receptor 3 signalling. Journal of Experimental Medicine (in press).
    • (1997) Journal of Experimental Medicine
    • Marth, T.1    Kelsall, B.L.2
  • 34
    • 0023203676 scopus 로고
    • The third component of complement (C3) is responsible for the intracellular survival of Leishmania major
    • Mosser DM & Edelson PJ (1987). The third component of complement (C3) is responsible for the intracellular survival of Leishmania major. Nature, 327: 329-331.
    • (1987) Nature , vol.327 , pp. 329-331
    • Mosser, D.M.1    Edelson, P.J.2
  • 36
    • 0024384964 scopus 로고
    • Tumor necrosis factor is involved in the T-cell-independent pathway of macrophage activation in scid mice
    • Bancroft GJ, Sheehan KC, Schreiber RD & Unanue ER (1989). Tumor necrosis factor is involved in the T-cell-independent pathway of macrophage activation in scid mice. Journal of Immunology, 143: 127-130.
    • (1989) Journal of Immunology , vol.143 , pp. 127-130
    • Bancroft, G.J.1    Sheehan, K.C.2    Schreiber, R.D.3    Unanue, E.R.4
  • 37
    • 0026357870 scopus 로고
    • Natural immunity: A T-cell-independent pathway of macrophage activation, defined in scid mouse
    • Bancroft GJ, Schreiber RD & Unanue ER (1991). Natural immunity: a T-cell-independent pathway of macrophage activation, defined in scid mouse. Immunological Reviews, 124: 5-24.
    • (1991) Immunological Reviews , vol.124 , pp. 5-24
    • Bancroft, G.J.1    Schreiber, R.D.2    Unanue, E.R.3
  • 38
    • 0027241272 scopus 로고
    • Toxoplasma gondii induces a T-independent IFN-γ response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-α
    • Sher A, Oswald IP, Hieny S & Gazzinelli RT (1993). Toxoplasma gondii induces a T-independent IFN-γ response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-α. Journal of Immunology, 150: 3982-3989.
    • (1993) Journal of Immunology , vol.150 , pp. 3982-3989
    • Sher, A.1    Oswald, I.P.2    Hieny, S.3    Gazzinelli, R.T.4
  • 39
    • 0030025945 scopus 로고    scopus 로고
    • Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin-10: The role of NK cells
    • Cardillo F, Voltarelli JC, Reed SG & Silva JS (1996). Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin-10: the role of NK cells. Infection and Immunity, 64: 128-134.
    • (1996) Infection and Immunity , vol.64 , pp. 128-134
    • Cardillo, F.1    Voltarelli, J.C.2    Reed, S.G.3    Silva, J.S.4
  • 40
    • 0028973003 scopus 로고
    • IL-1β is required for IL-12 to induce production of IFN-γ by NK cells
    • Hunter CA, Chizzonite R & Remington JS (1995). IL-1β is required for IL-12 to induce production of IFN-γ by NK cells. Journal of Immunology, 155: 4347-4354.
    • (1995) Journal of Immunology , vol.155 , pp. 4347-4354
    • Hunter, C.A.1    Chizzonite, R.2    Remington, J.S.3
  • 41
    • 0028818320 scopus 로고
    • Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-γ by natural killer cells in vitro
    • . Carson WE, Ross ME, Baiocchi RA, Marien MJ, Boiani N, Grabstein K & Caligiuri M (1995). Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-γ by natural killer cells in vitro. Journal of Clinical Investigation, 96: 2578-2582.
    • (1995) Journal of Clinical Investigation , vol.96 , pp. 2578-2582
    • Carson, W.E.1    Ross, M.E.2    Baiocchi, R.A.3    Marien, M.J.4    Boiani, N.5    Grabstein, K.6    Caligiuri, M.7
  • 42
    • 0028987734 scopus 로고
    • Transforming growth factor-β inhibits interleukin-12-induced production of interferon-γ by natural killer cells: A role for transforming growth factor-β in the regulation of T cell-mediated resistance to Toxoplasma gondii
    • Hunter CA, Bermudez L, Beernink H, Waegell W & Remington JS (1995). Transforming growth factor-β inhibits interleukin-12-induced production of interferon-γ by natural killer cells: a role for transforming growth factor-β in the regulation of T cell-mediated resistance to Toxoplasma gondii. European Journal of Immunology, 25: 994-1000.
    • (1995) European Journal of Immunology , vol.25 , pp. 994-1000
    • Hunter, C.A.1    Bermudez, L.2    Beernink, H.3    Waegell, W.4    Remington, J.S.5
  • 43
    • 0026733615 scopus 로고
    • Leishmania donovani infection in scid mice: Lack of tissue response and in vivo macrophage activation correlates with failure to trigger natural-killer cell-derived gamma interferon production in vitro
    • Kaye PM & Bancroft GJ (1992). Leishmania donovani infection in scid mice: Lack of tissue response and in vivo macrophage activation correlates with failure to trigger natural-killer cell-derived gamma interferon production in vitro. Infection and Immunity, 60: 4335-4342.
    • (1992) Infection and Immunity , vol.60 , pp. 4335-4342
    • Kaye, P.M.1    Bancroft, G.J.2
  • 44
    • 0027500332 scopus 로고
    • Reconstitution of C.B.-17 SCID mice with BALB/c T cells initiates a T helper type-1 response and renders them capable of healing Leishmania major infection
    • Varkila K, Chatelain R, Leal LM & Coffman RL (1993). Reconstitution of C.B.-17 SCID mice with BALB/c T cells initiates a T helper type-1 response and renders them capable of healing Leishmania major infection. European Journal of Immunology, 23: 1531-1538.
    • (1993) European Journal of Immunology , vol.23 , pp. 1531-1538
    • Varkila, K.1    Chatelain, R.2    Leal, L.M.3    Coffman, R.L.4
  • 45
    • 0026056142 scopus 로고
    • IFN-γ modulates the early development of Th1 and Th2 responses in murine model of cutaneous leishmaniasis
    • Scott P (1991). IFN-γ modulates the early development of Th1 and Th2 responses in murine model of cutaneous leishmaniasis. Journal of Immunology, 147: 3149-3155.
    • (1991) Journal of Immunology , vol.147 , pp. 3149-3155
    • Scott, P.1
  • 47
    • 0024540908 scopus 로고
    • Reciprocal expression of interferon-gamma or IL-4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets
    • Heinzel FP, Sadick MD, Holaday BJ & Locksley RM (1989). Reciprocal expression of interferon-gamma or IL-4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. Journal of Experimental Medicine, 169: 59-72.
    • (1989) Journal of Experimental Medicine , vol.169 , pp. 59-72
    • Heinzel, F.P.1    Sadick, M.D.2    Holaday, B.J.3    Locksley, R.M.4
  • 48
    • 0025133974 scopus 로고
    • Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon γ-independent mechanism
    • Sadick MD, Heinzel FP, Holaday BJ, Pu RT, Dawkins RS & Locksley RM (1990). Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon γ-independent mechanism. Journal of Experimental Medicine, 171: 115-127.
    • (1990) Journal of Experimental Medicine , vol.171 , pp. 115-127
    • Sadick, M.D.1    Heinzel, F.P.2    Holaday, B.J.3    Pu, R.T.4    Dawkins, R.S.5    Locksley, R.M.6
  • 49
    • 0024236111 scopus 로고
    • Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens
    • Scott P, Natovitz P, Coffman RL, Pearce E & Sher A (1988). Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. Journal of Experimental Medicine, 168: 1675-1684.
    • (1988) Journal of Experimental Medicine , vol.168 , pp. 1675-1684
    • Scott, P.1    Natovitz, P.2    Coffman, R.L.3    Pearce, E.4    Sher, A.5
  • 50
    • 0023726937 scopus 로고
    • Anti-proliferative effect of IFN-γ in immunoregulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones
    • . Gajewski TF & Fitch FW (1988). Anti-proliferative effect of IFN-γ in immunoregulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. Journal of Immunology, 140: 4245-4251.
    • (1988) Journal of Immunology , vol.140 , pp. 4245-4251
    • Gajewski, T.F.1    Fitch, F.W.2
  • 52
    • 0028970060 scopus 로고
    • Interleukin-12: A pro-inflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptative immunity
    • Trinchieri G (1995). Interleukin-12: a pro-inflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptative immunity. Annual Review of Immunology, 13: 252-276.
    • (1995) Annual Review of Immunology , vol.13 , pp. 252-276
    • Trinchieri, G.1
  • 53
    • 0027336689 scopus 로고
    • Development of Th1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
    • Hsieh CS, Macatonia SE, Tripp CS, Wolf S, O'Garra A & Murphy KM (1993). Development of Th1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science, 260: 547-549.
    • (1993) Science , vol.260 , pp. 547-549
    • Hsieh, C.S.1    Macatonia, S.E.2    Tripp, C.S.3    Wolf, S.4    O'Garra, A.5    Murphy, K.M.6
  • 54
    • 0027491655 scopus 로고
    • IL-12 acts directly on CD4+ T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming
    • Seder RA, Gazzinelli RT, Sher A & Paul WE (1993). IL-12 acts directly on CD4+ T cells to enhance priming for IFN-γ production and diminishes IL-4 inhibition of such priming. Proceedings of the National Academy of Sciences, USA, 90: 10188-10192.
    • (1993) Proceedings of the National Academy of Sciences, USA , vol.90 , pp. 10188-10192
    • Seder, R.A.1    Gazzinelli, R.T.2    Sher, A.3    Paul, W.E.4
  • 57
    • 0025082313 scopus 로고
    • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • Le Gros G, Ben-Sasson SZ, Seder R, Finkelman FD & Paul WE (1990). Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. Journal of Experimental Medicine, 172: 921-929.
    • (1990) Journal of Experimental Medicine , vol.172 , pp. 921-929
    • Le Gros, G.1    Ben-Sasson, S.Z.2    Seder, R.3    Finkelman, F.D.4    Paul, W.E.5
  • 59
    • 0027255488 scopus 로고
    • Natural killer cells are a source of IFN-γ that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice
    • Schartor TM & Scott P (1993). Natural killer cells are a source of IFN-γ that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice. Journal of Experimental Medicine, 178: 567-577.
    • (1993) Journal of Experimental Medicine , vol.178 , pp. 567-577
    • Schartor, T.M.1    Scott, P.2
  • 60
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell delopment in experimental leishmaniasis
    • Scharton-Kersten T, Afonso LCC, Wysocka M, Trinchieri G & Scott P (1995). IL-12 is required for natural killer cell activation and subsequent T helper 1 cell delopment in experimental leishmaniasis. Journal of Immunology, 154: 5320-5330.
    • (1995) Journal of Immunology , vol.154 , pp. 5320-5330
    • Scharton-Kersten, T.1    Afonso, L.C.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 61
    • 0028950126 scopus 로고
    • Interleukin 12 is effective treatment for an established systemic intracellular infection: Experimental visceral leishmaniasis
    • Murray HW & Hariprashad J (1995). Interleukin 12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis. Journal of Experimental Medicine, 181: 387-391.
    • (1995) Journal of Experimental Medicine , vol.181 , pp. 387-391
    • Murray, H.W.1    Hariprashad, J.2
  • 62
    • 0029076809 scopus 로고
    • Endogenous interleukin-12 (IL-12) is required for control of Th2 CD4+ T cell responses capable of exacerbating leishmaniasis in normally resistant C57BL/6 mice
    • Heinzel FP, Rerko RM, Ahmed F & Pearlman E (1995). Endogenous interleukin-12 (IL-12) is required for control of Th2 CD4+ T cell responses capable of exacerbating leishmaniasis in normally resistant C57BL/6 mice. Journal of Immunology, 155: 730-739.
    • (1995) Journal of Immunology , vol.155 , pp. 730-739
    • Heinzel, F.P.1    Rerko, R.M.2    Ahmed, F.3    Pearlman, E.4
  • 66
    • 0030045393 scopus 로고    scopus 로고
    • Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigenspecific IFN-γ responses and increased production of helper 2 cytokines
    • Krishnan L, Guilbert LJ, Russell AS, Wegmann TG, Mosmann T & Belosevic M (1996). Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigenspecific IFN-γ responses and increased production of helper 2 cytokines. Journal of Immunology, 156: 644-652.
    • (1996) Journal of Immunology , vol.156 , pp. 644-652
    • Krishnan, L.1    Guilbert, L.J.2    Russell, A.S.3    Wegmann, T.G.4    Mosmann, T.5    Belosevic, M.6
  • 67
    • 0026776079 scopus 로고
    • Biology and biochemistry of the chemokines: A family of chemotactic and inflammatory cytokines
    • Miller MD & Krangel MS (1992). Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Critical Reviews in Immunology, 12: 17-46.
    • (1992) Critical Reviews in Immunology , vol.12 , pp. 17-46
    • Miller, M.D.1    Krangel, M.S.2
  • 69
    • 43949153331 scopus 로고
    • CC chemokines in allergic inflammation
    • Baggiolini M & Dahinden CA (1994). CC chemokines in allergic inflammation. Immunology Today, 15: 127-133.
    • (1994) Immunology Today , vol.15 , pp. 127-133
    • Baggiolini, M.1    Dahinden, C.A.2
  • 70
    • 0028202481 scopus 로고
    • The molecular biology of leukocyte chemoattractant receptors
    • Murphy PM (1994). The molecular biology of leukocyte chemoattractant receptors. Annual Review of Immunology, 12: 593-633.
    • (1994) Annual Review of Immunology , vol.12 , pp. 593-633
    • Murphy, P.M.1
  • 72
    • 0030588706 scopus 로고    scopus 로고
    • The genes for chemokines MuMig and Crg-2 are induced in protozoan and viral infections in response to IFN-γ with patterns of tissue expression that suggest nonredundant roles in vivo
    • Amichay D, Gazzinelli RT, Karupiah G, Moench T, Sher A & Farber J (1996). The genes for chemokines MuMig and Crg-2 are induced in protozoan and viral infections in response to IFN-γ with patterns of tissue expression that suggest nonredundant roles in vivo. Journal of Immunology, 157: 4511-4520.
    • (1996) Journal of Immunology , vol.157 , pp. 4511-4520
    • Amichay, D.1    Gazzinelli, R.T.2    Karupiah, G.3    Moench, T.4    Sher, A.5    Farber, J.6
  • 74
    • 0029978144 scopus 로고    scopus 로고
    • Leishmania major: Infection of human monocytes induces expression of IL-8 and MCAF
    • Badolato R, Sacks D, Savoia D & Musso T (1996). Leishmania major: infection of human monocytes induces expression of IL-8 and MCAF. Experimental Parasitology, 82: 21-26.
    • (1996) Experimental Parasitology , vol.82 , pp. 21-26
    • Badolato, R.1    Sacks, D.2    Savoia, D.3    Musso, T.4
  • 75
    • 0031105071 scopus 로고    scopus 로고
    • Leishmania major: Promastigotes induce expression of a subset of chemokine genes in murine macrophages
    • Racoosin EL & Beverley SM (1997). Leishmania major: promastigotes induce expression of a subset of chemokine genes in murine macrophages. Experimental Parasitology, 85: 283-295.
    • (1997) Experimental Parasitology , vol.85 , pp. 283-295
    • Racoosin, E.L.1    Beverley, S.M.2
  • 77
    • 0026529405 scopus 로고
    • IL-10 inhibits parasite killing and nitrogen oxide production by IFN-γ activated macrophages
    • Gazzinelli RT, Oswald IP, James S & Sher A (1992). IL-10 inhibits parasite killing and nitrogen oxide production by IFN-γ activated macrophages. Journal of Immunology, 148: 1792-1796.
    • (1992) Journal of Immunology , vol.148 , pp. 1792-1796
    • Gazzinelli, R.T.1    Oswald, I.P.2    James, S.3    Sher, A.4
  • 78
    • 0026559756 scopus 로고
    • IL-10 synergizes with IL-4 and transforming growth factor-β to inhibit macrophage cytotoxic activity
    • Oswald IP, Gazzinelli RT, Sher A & James SL (1992). IL-10 synergizes with IL-4 and transforming growth factor-β to inhibit macrophage cytotoxic activity. Journal of Immunology, 148: 3578-3582.
    • (1992) Journal of Immunology , vol.148 , pp. 3578-3582
    • Oswald, I.P.1    Gazzinelli, R.T.2    Sher, A.3    James, S.L.4
  • 80
    • 0030298134 scopus 로고    scopus 로고
    • Trypanosoma cruzi. IL-10, TNF, IFN-γ, and IL-12 regulate innate and acquired immunity to infection
    • Abrahamsohn IA & Coffman RL (1996). Trypanosoma cruzi. IL-10, TNF, IFN-γ, and IL-12 regulate innate and acquired immunity to infection. Experimental Parasitology, 84: 231-244.
    • (1996) Experimental Parasitology , vol.84 , pp. 231-244
    • Abrahamsohn, I.A.1    Coffman, R.L.2
  • 81
    • 0029959459 scopus 로고    scopus 로고
    • In the absence of endogenous IL-10 mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompaed by overproduction of IL-12, IFN-γ, and TNF-α
    • Gazzinelli RT, Wysocka M, Hieny S, Scharton-Kersten T, Cheever A, Kühn R, Müller W, Trinchieri G & Sher A (1996). In the absence of endogenous IL-10 mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompaed by overproduction of IL-12, IFN-γ, and TNF-α. Journal of Immunology, 157: 798-805.
    • (1996) Journal of Immunology , vol.157 , pp. 798-805
    • Gazzinelli, R.T.1    Wysocka, M.2    Hieny, S.3    Scharton-Kersten, T.4    Cheever, A.5    Kühn, R.6    Müller, W.7    Trinchieri, G.8    Sher, A.9
  • 83
    • 0025741792 scopus 로고
    • Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor-β (TGF-β)
    • Silva SJ, Twardzik DR & Reed SG (1991). Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor-β (TGF-β). Journal of Experimental Medicine, 174: 539-545.
    • (1991) Journal of Experimental Medicine , vol.174 , pp. 539-545
    • Silva, S.J.1    Twardzik, D.R.2    Reed, S.G.3
  • 86
    • 0024352297 scopus 로고
    • Macrophage activation by interferon-gamma from host-protective T cells is inhibited by interleukin (IL)3 and IL4 produced by disease-promoting T cells in leishmaniasis
    • Liew FY, Millott S, Li Y, Lelchuk R, Chan WL & Ziltener H (1989). Macrophage activation by interferon-gamma from host-protective T cells is inhibited by interleukin (IL)3 and IL4 produced by disease-promoting T cells in leishmaniasis. European Journal of Immunology, 19: 1227-1232.
    • (1989) European Journal of Immunology , vol.19 , pp. 1227-1232
    • Liew, F.Y.1    Millott, S.2    Li, Y.3    Lelchuk, R.4    Chan, W.L.5    Ziltener, H.6
  • 88
    • 0028853663 scopus 로고
    • Role of nitric oxide in parasitic infections
    • James S (1995). Role of nitric oxide in parasitic infections. Microbiological Reviews, 59: 533-547.
    • (1995) Microbiological Reviews , vol.59 , pp. 533-547
    • James, S.1
  • 89
    • 0028294578 scopus 로고
    • Intracellular infection by Leishmania donovaniinhibits macrophage apoptosis
    • Moore KJ & Matlashewski G (1994). Intracellular infection by Leishmania donovaniinhibits macrophage apoptosis. Journal of Immunology, 152: 2930-2937
    • (1994) Journal of Immunology , vol.152 , pp. 2930-2937
    • Moore, K.J.1    Matlashewski, G.2
  • 92
    • 0028348042 scopus 로고
    • Mitogen and antigen specific proferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates
    • Candolfi E, Hunter CA & Remington JS (1994). Mitogen and antigen specific proferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates. Infection and Immunity, 62: 1995-2001
    • (1994) Infection and Immunity , vol.62 , pp. 1995-2001
    • Candolfi, E.1    Hunter, C.A.2    Remington, J.S.3
  • 93
    • 0030062328 scopus 로고    scopus 로고
    • Contribution of nitric oxide to the host parasite equilibrium in toxoplasmosis
    • Hayashi S, Chan CC, Gazzinelli RT & Roberge FG (1996). Contribution of nitric oxide to the host parasite equilibrium in toxoplasmosis. Journal of Immunology, 156: 1476-1481.
    • (1996) Journal of Immunology , vol.156 , pp. 1476-1481
    • Hayashi, S.1    Chan, C.C.2    Gazzinelli, R.T.3    Roberge, F.G.4
  • 94
    • 0030970867 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase knockout mice are susceptible to chronic but not acute infection with avirulent strain of Toxoplasma gondii
    • Scharton-Kersten T, Yap G & Sher A (1997). Inducible nitric oxide synthase knockout mice are susceptible to chronic but not acute infection with avirulent strain of Toxoplasma gondii. Journal of Experimental Medicine, 185: 1261-1273.
    • (1997) Journal of Experimental Medicine , vol.185 , pp. 1261-1273
    • Scharton-Kersten, T.1    Yap, G.2    Sher, A.3
  • 95
    • 0025191159 scopus 로고
    • Activated macrophages destroy Leishmania major amastigotes by an L-arginine dependent killing mechanism
    • Green SJ, Meltzer MS, Hibbs JB & Nacy CA (1990). Activated macrophages destroy Leishmania major amastigotes by an L-arginine dependent killing mechanism. Journal of Immunology, 144: 278-283.
    • (1990) Journal of Immunology , vol.144 , pp. 278-283
    • Green, S.J.1    Meltzer, M.S.2    Hibbs, J.B.3    Nacy, C.A.4
  • 96
    • 0025300228 scopus 로고
    • Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine
    • Liew FY, Millott S, Parkinson C, Palmer RMJ & Moncada S (1990). Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. Journal of Immunology, 144: 4794-4797.
    • (1990) Journal of Immunology , vol.144 , pp. 4794-4797
    • Liew, F.Y.1    Millott, S.2    Parkinson, C.3    Palmer, R.M.J.4    Moncada, S.5
  • 98
    • 0027471132 scopus 로고
    • Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites
    • . Schofield L & Hackett F (1993). Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites. Journal of Experimental Medicine, 177: 145-153.
    • (1993) Journal of Experimental Medicine , vol.177 , pp. 145-153
    • Schofield, L.1    Hackett, F.2
  • 99
    • 0030039444 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol toxin of Plasmodium up-regulates intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and E-selectin expression in vascular endothelium cells and increases leukocyte and parasite cytoadherence via tyrosine kinase-dependent signal transduction
    • Schofield L, Novakovic S, Gerold P, Schwarz RT, McConville MJ & Tachado SD (1996). Glycosylphosphatidylinositol toxin of Plasmodium up-regulates intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and E-selectin expression in vascular endothelium cells and increases leukocyte and parasite cytoadherence via tyrosine kinase-dependent signal transduction. Journal of Immunology, 156: 1886-1896.
    • (1996) Journal of Immunology , vol.156 , pp. 1886-1896
    • Schofield, L.1    Novakovic, S.2    Gerold, P.3    Schwarz, R.T.4    McConville, M.J.5    Tachado, S.D.6
  • 100
    • 0030042523 scopus 로고    scopus 로고
    • Glycosytphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelium cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway
    • Tachado SD, Gerold P, McConville MJ, Baldwin T, Quilici B, Schwarz RT & Schofield L (1996). Glycosytphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelium cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway. Journal of Immunology, 156: 1897-1907.
    • (1996) Journal of Immunology , vol.156 , pp. 1897-1907
    • Tachado, S.D.1    Gerold, P.2    McConville, M.J.3    Baldwin, T.4    Quilici, B.5    Schwarz, R.T.6    Schofield, L.7
  • 101
    • 0028630691 scopus 로고
    • Glycosylphosphatidylinositol toxin of Trypanosoma brucei regulates IL-1β and TNF-α expression in macrophages by protein tyrosine kinase mediated signal transducon
    • Tachado SD & Schofield L (1994). Glycosylphosphatidylinositol toxin of Trypanosoma brucei regulates IL-1β and TNF-α expression in macrophages by protein tyrosine kinase mediated signal transducon. Biochemical and Biophysical Research Communications, 205: 984-991.
    • (1994) Biochemical and Biophysical Research Communications , vol.205 , pp. 984-991
    • Tachado, S.D.1    Schofield, L.2
  • 103
    • 0025849761 scopus 로고
    • Leishmania donovani lipophosphoglycan selectively inhibits signal transduction in macrophages
    • Descoteaux A, Turco SJ, Sacks DL & Matlashewski G (1991). Leishmania donovani lipophosphoglycan selectively inhibits signal transduction in macrophages. Journal of Immunology, 146: 2747-2753.
    • (1991) Journal of Immunology , vol.146 , pp. 2747-2753
    • Descoteaux, A.1    Turco, S.J.2    Sacks, D.L.3    Matlashewski, G.4
  • 104
    • 0025667811 scopus 로고
    • Effects of glycolipids of Leishmania parasites on human monocyte activity. Inhibition by lipophosphoglycan
    • Frankenburg S, Leibovici V, Mansbach N, Turco SJ & Rosen G (1990). Effects of glycolipids of Leishmania parasites on human monocyte activity. Inhibition by lipophosphoglycan. Journal of Immunology, 145: 4284-4289.
    • (1990) Journal of Immunology , vol.145 , pp. 4284-4289
    • Frankenburg, S.1    Leibovici, V.2    Mansbach, N.3    Turco, S.J.4    Rosen, G.5


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