A new class of defective hepatitis B virus genomes with an internal poly(dA) sequence

Virology

Volumn 239, Issue 2, 1997, Pages 402-412

  Sommer, Gunhild ^a   Günther, Stephan ^a   Sterneck, Martina ^a   Otto, Stephanie ^a   Will, Hans ^a  

^a LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHRONIC HEPATITIS; GENE AMPLIFICATION; GENE EXPRESSION; GENE SEQUENCE; GENOME; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; PATHOGENICITY; PLASMID; POLYADENYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING;

ANIMALIA; DNA VIRUSES; HEPATITIS B VIRUS; RNA VIRUSES;

EID: 0031583819     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1997.8898     Document Type: Article

References (42)

1. Ackrill A. M., Naoumov N. V., Eddleston A. L. W. F., Williams R. Comparison of pre-core/core hepatitis B virus region in liver tissue and serum from patients with chronic hepatitis B infection. J. Hepatol. 16:1992;224-227.
2. Bartenschlager R., Schaller H. Hepadnaviral assembly is initiated by polymerase binding to the encapsidation signal in the viral RNA genome. EMBO J. 11:1992;3413-3420.
3. Blum H. E. Variants of hepatitis B, C and D viruses: Molecular biology and clinical significance. Digestion. 56:1995;85-95.
4. Carman W. F. The clinical significance of surface antigen variants of hepatitis B virus. J. Viral Hepatitis. 4:1997;11-20.
5. Chen Y., Marion P. L. Amino acids essential for RNase H activity of hepadnaviruses are also required for efficient elongation of minus-strand viral DNA. J. Virol. 70:1996;6151-6156.
6. Fallows D. A., Goff S. P. Hepadnaviruses: Current models of RNA encapsidation and reverse transcription. Adv. Virus Res. 46:1996;165-194.
7. Feitelson M., Lega L., Guo J., Resti M., Rossi M. E., Azzari C., Blumberg B. S., Vierucci A. Pathogenesis of posttransfusion viral hepatitis in children with β-Thalassemia. Hepatology. 19:1994;558-568.
8. Galibert F., Mandart E., Fitoussi F., Tiollais P., Charnay P. Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned inE. coli. Nature. 281:1979;646-650.
9. Gerelsaikhan T., Tavis J. E., Bruss V. Hepatitis B virus nucleocapsid envelopment does not occur without genomic DNA synthesis. J. Virol. 70:1996;4269-4274.
10. Grabko V. I., Chistyakova L. G., Lyapustin V. N., Korobko V. G., Miroshnikov A. I. Reverse transcription, amplification and sequencing of poliovirus RNA byTaq. FEBS Lett. 387:1996;189-192.
11. Grebennikova T. V., Glukhov A. J., Chistyakova L. G., Kiselev V. I., Severin E. S. Detection of interleukin-2α RNA and determination of MDR-1 gene expression by combined reverse transcription and amplification usingThermus thermophilus. Mol. Biol. 29:1995;542-547.
12. Günther S., Baginski S., Kissel H., Reinke P., Krüger D. H., Will H., Meisel H. Accumulation and persistence of hepatitis B virus core gene deletion mutants in renal transplant patients are associated with end-stage liver disease. Hepatology. 24:1996;751-758.
13. Günther S., Li B.-C., Miska S., Krüger D. H., Meisel H., Will H. A novel method for efficient amplification of whole hepatitis B virus genomes permits rapid functional analysis and reveals deletion mutants in immunosuppressed patients. J. Virol. 69:1995;5437-5444.
14. Günther S., Netter H. J., Sommer G., Wollersheim-Kolmer M., Li B.-C., Chassot S., Iwanska A., Piwon N., Will H. Structural and functional complexity of hepatitis B virus variant genomes and virus populations. Proceedings of the IX Triennial International Symposium on Viral Hepatitis and Liver Disease. 1997a.
15. Günther S., Sommer G., Iwanska A., Will H. Heterogeneity and common features of defective hepatitis B virus genomes derived from spliced pregenomic RNA. Virology. 238:1997b;363-371.
16. Hadziyannis S. J. Hepatitis B e antigen negative chronic hepatitis B: From clinical recognition to pathogenesis and treatment. Viral Hepatitis. 1:1995;7-36.
17. Hasegawa K., Huang J., Rogers S. A., Blum H. E., Liang T. J. Enhanced replication of a hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. J. Virol. 68:1994;1651-1659.
18. Hilger C., Velhagen I., Zentgraf H., Schröder C. H. Diversity of hepatitis B virus X gene-related transcripts in hepatocellular carcinoma: A novel polyadenylation site on viral DNA. J. Virol. 65:1991;4284-4291.
19. Hoofnagle J. H., Di Bisceglie A. M. The treatment of chronic viral hepatitis. N. Engl. J. Med. 336:1997;347-355.
20. Jones M. D., Foulkes N. S. Reverse transcription of mRNA byThermus aquaticus. Nucleic Acids Res. 17:1989;8387-8388.
21. Junker-Niepmann M., Bartenschlager R., Schaller H. A shortcis. EMBO J. 9:1990;3389-3396.
22. Loeb D. D., Hirsch R. C., Ganem D. Sequence-independent RNA cleavages generate the primers for plus strand DNA synthesis in hepatitis B viruses: Implications for other reverse transcribing elements. EMBO J. 10:1991;3533-3540.
23. Miyakawa Y., Okamoto H., Mayumi M. The molecular basis of hepatitis B e antigen (HBeAg)-negative infections. J. Viral Hepatitis. 4:1997;1-8.
24. Myers T. W., Gelfand D. H. Reverse transcription and DNA amplification by aThermus thermophilus. Biochemistry. 30:1991;7661-7666.
25. Nassal M., Schaller H. Hepatitis B virus replication - An update. J. Viral Hepatitis. 3:1996;217-226.
26. Netter H. J., Chassot S., Chang S.-F., Cova L., Will H. Sequence heterogeneity of heron hepatitis B virus genomes determined by full-length DNA amplification and direct sequencing reveals novel and unique features. J. Gen. Virol. 78:1997;1707-1718.
27. Nowak M. A., Bonhoeffer S., Hill A. M., Boehme R., Thomas H. C., McDade H. Viral dynamics in hepatitis B virus infection. Proc. Natl. Acad. Sci. USA. 93:1996;4398-4402.
28. Okamoto H., Tsuda F., Mayumi M. Defective mutants of hepatitis B virus in the circulation of symptom-free carriers. Japan. J. Exp. Med. 57:1987;217-221.
29. Pult I., Chouard T., Wieland S., Klemenz R., Yaniv M., Blum H. E. A hepatitis B virus mutant with a new hepatocyte nuclear factor binbing site emerging in transplant-transmitted fulminant hepatitis B. Hepatology. 25:1997;1507-1515.
30. Seeger C., Ganem D., Varmus H. E. Biochemical and genetic evidence for the hepatitis B virus replication strategy. Science. 232:1986;477-484.
31. Simonsen C. C., Levinson A. D. Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids. Mol. Cell. Biol. 3:1983;2250-2258.
32. Staprans S., Loeb D. D., Ganem D. Mutations affecting hepadnavirus plus-strand DNA synthesis dissociate primer cleavage from translocation and reveal the origin of linear viral DNA. J. Virol. 65:1991;1255-1262.
33. Summers J., Mason W. S. Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate. Cell. 29:1982;403-415.
34. Tse W. T., Forget B. G. Reverse transcription and direct amplification of cellular RNA transcripts byTaq. Gene. 88:1990;293-296.
35. Tuttleman J. S., Pourcel C., Summers J. Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells. Cell. 47:1986;451-460.
36. Vartanian L.-P., Plikat U., Henry M., Mahieux R., Guillemot L., Meyerhans A., Wain-Hobson S. HIV genetic variation is directed and restricted by DNA precursor availability. J. Mol. Biol. 270:1997;139-151.
37. Wei Y., Tavis J. E., Ganem D. Relationship between viral DNA synthesis and virion envelopment in hepatitis B viruses. J. Virol. 70:1996;6455-6458.
38. Will H., Reiser W., Weimer T., Pfaff E., Büscher M., Sprengel R., Cattaneo R., Schaller H. Replication strategy of human hepatitis B virus. J. Virol. 61:1987;904-911.
39. Yaginuma K., Koike K. Identification of a promoter region for 3.6-kilobase mRNA of hepatitis B virus and specific cellular binding protein. J. Virol. 63:1989;2914-2920.
40. Yang W., Summers J. Illegitimate replication of linear hepadnavirus DNA through nonhomologous recombination. J. Virol. 69:1995;4029-4036.
41. Yuh C.-H., Chang Y.-L., Ting L.-P. Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus. J. Virol. 66:1992;4073-4084.
42. Zeuzem S., De Man R. A., Honkoop P., Roth W. K., Schalm S. W., Schmidt J. M. Dynamics of hepatitis B virus infectionin vivo. J. Hepatol. 3:1997;431-436.