A hepatitis B virus mutant with a new hepatocyte nuclear factor 1 binding site emerging in transplant-transmitted fulminant hepatitis B

Hepatology

Volumn 25, Issue 6, 1997, Pages 1507-1515

  Pult, Irmgard ^a,b   Chouard, Tanguy ^a   Wieland, Stefan ^a,c   Klemenz, Roman ^b   Yaniv, Moshe ^a   Blum, Hubert E ^a,c,d  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b INSTITUT PASTEUR   (France)

^c UNIVERSITY OF FREIBURG   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA;

ADULT; ARTICLE; BASE PAIRING; BINDING SITE; CASE REPORT; DISEASE SEVERITY; FEMALE; GENE INSERTION; HEPATITIS B; HUMAN; MOLECULAR CLONING; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STRAIN DIFFERENCE; VIRUS DNA CELL DNA INTERACTION; VIRUS INFECTIVITY; VIRUS MUTATION; VIRUS REPLICATION;

BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; DNA TRANSPOSABLE ELEMENTS; DNA, VIRAL; DNA-BINDING PROTEINS; FEMALE; GENOME, VIRAL; HEPATITIS B; HEPATITIS B VIRUS; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HUMANS; LIVER TRANSPLANTATION; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; POPULATION; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; VIRUS REPLICATION;

EID: 0030979383     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510250633     Document Type: Article

References (17)

1. Davies SE, Portmann BC, O'Grady JG, Aldis PM, Chaggar K, Alexander GJ, Williams R. Hepatic histological findings after transplantation for chronic hepatitis B virus infection, including a unique pattern of fibrosing cholestatic hepatitis. HEPATOLOGY 1991;13:150-157.
2. Phillips MJ, Cameron R, Flowers MA, Blendis LM, Greig PD, Wanless I, Sherman M, et al. Posttransplant recurrent hepatitis B viral liver disease. Viral-burden, steatoviral, and fibroviral hepatitis B. Am J Pathol 1992;140:1295-1308.
3. Mason AL, Wick M, White HM, Benner KG, Lee RG, Regenstein F, Riely CA, et al. Increased hepatocyte expression of hepatitis B virus transcription in patients with features of fibrosing cholestatic hepatitis. Gastroenterology 1993;105:237-244.
4. Blum HE. Variants of hepatitis B, C and D viruses: molecular biology and clinical significance. Digestion 1995;56:85-95.
5. Carman WF, Fagan EA, Hadziyannis S, Karayiannis P, Tassopoulos NC, Williams R, Thomas HC. Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis. HEPATOLOGY 1991;14:219-222.
6. Kojima M, Shimizu M, Tsuchimochi T, Koyasu M, Tanaka S, Iizuka H, Tanaka T, et al. Posttransfusion fulminant hepatitis B associated with precore-defective HBV mutants. Vox Sang 1991;60:34-39.
7. Kosaka Y, Takase K, Kojima M, Shimizu M, Inoue K, Yoshiba M, Tanaka S, et al. Fulminant hepatitis B: induction by hepatitis B virus mutants defective in the precore region and incapable of encoding e antigen. Gastroenterology 1991;100:1087-1094.
8. Liang TJ, Hasegawa K, Rimon N, Wands JR, Ben Porath E. A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. N Engl J Med 1991;324:1705-1709.
9. Omata M, Ehata T, Yokosuka O, Hosoda K, Ohto M. Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis. N Engl J Med 1991;324:1699-1704.
10. Terazawa S, Kojima M, Yamanaka T, Yotsumoto S, Okamoto H, Tsuda F, Miyakawa Y, et al. Hepatitis B virus mutants with precore-region defects in two babies with fulminant hepatitis and their mothers positive for antibody to hepatitis B e antigen. Pediatric Res 1991;29:5-9.
11. Yotsumoto S, Kojima M, Shoji I, Yamamoto K, Okamoto H, Mishiro S. Fulminant hepatitis related to transmission of hepatitis B variants with precore mutations between spouses. HEPATOLOGY 1992;16:31-35.
12. Aye TT, Uchida T, Becker SO, Hirashima M, Shikata T, Komine F, Moriyama M, et al. Variations of hepatitis B virus precore/core gene sequence in acute and fulminant hepatitis B. Dig Dis Sci 1994;39:1281-1287.
13. Kaneko M, Uchida T, Moriyama M, Arakawa Y, Shikata T, Gotoh K, Mima S. Probable implication of mutations of the X open reading frame in the onset of fulminant hepatitis B. J Med Virol 1995;47:204-208.
14. Sato S, Suzuki K, Akahane Y, Akamatsu K, Akiyama K, Yunomura K, Tsuda F, et al. Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis. Ann Intern Med 1995;122:241-248.
15. Fang JW, Tung FY, Davis GL, Dolson DJ, van Thiel DH, Lau JY. Fibrosing cholestatic hepatitis in a transplant recipient with hepatitis B virus precore mutant. Gastroenterology 1993;105:901-904.
16. Chen CH, Chen PJ, Chu JS, Yeh KH, Lai MY, Chen DS. Fibrosing cholestatic hepatitis in a hepatitis B surface antigen carrier after renal transplantation. Gastroenterology 1994;107:1514-1518.
17. McIvor C, Morton J, Bryant A, Cooksley WG, Durrant S, Walker N. Fatal reactivation of precore mutant hepatitis B virus associated with fibrosing cholestatic hepatitis after bone marrow transplantation. Ann Intern Med 1994;121:274-275.