Analysis of protein-protein interactions and the effects of amino acid mutations on their energetics. The importance of water molecules in the binding epitope

Journal of Molecular Biology

Volumn 269, Issue 2, 1997, Pages 281-297

  Covell, D G ^a   Wallqvist, A ^a  

^a SAIC FREDERICK INC   (United States)

Author keywords

Barnase barstar; Binding energy; Bound water; D1.3 E5.2; D1.3 HEL; Mutations

Indexed keywords

AMINO ACID; ANTIBODY; EPITOPE; LYSOZYME; MUTANT PROTEIN; PROTEIN; WATER;

AMINO ACID SUBSTITUTION; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME BINDING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

EID: 0031556018     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1028     Document Type: Article

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